Enzyme Inhibitors

Mechanism-based inactivation of human leukocyte elastase via an enzyme-induced sulfonamide fragmentation process

Enzyme Inhibitors / Humans / Drug Design / Fragmentation / Enzyme / Active site / Time Dependent / Substrate Specificity / Serine Protease / Methyl Ester / Biochemistry and cell biology / Active site / Time Dependent / Substrate Specificity / Serine Protease / Methyl Ester / Biochemistry and cell biology

Comparative study of catalase-peroxidases (KatGs)

Kinetics / Enzyme Inhibitors / Enzyme Kinetics / Peroxidase / Mycobacterium tuberculosis / Escherichia coli / Bacteria / Catalase / Enzyme / Hydrogen Peroxide / Anti-Bacterial Agents / Peroxidases / Multienzyme complexes / Cyanides / High Sensitivity / Isoniazid / Hydrogen-Ion Concentration / Histidine / Biochemistry and cell biology / Escherichia coli / Bacteria / Catalase / Enzyme / Hydrogen Peroxide / Anti-Bacterial Agents / Peroxidases / Multienzyme complexes / Cyanides / High Sensitivity / Isoniazid / Hydrogen-Ion Concentration / Histidine / Biochemistry and cell biology

Esterase and lipase in camel tick Hyalomma dromedarii (Acari: Ixodidae) during embryogenesis

Physiology / Kinetics / Enzyme Inhibitors / Animals / Camels / Egg Proteins / Enzyme / Metals / Substrate Specificity / Isoenzymes / Molecular Mass / Metal ion / Esterases / Ixodidae / Lipase / Diglycerides / Biochemistry and cell biology / Egg Proteins / Enzyme / Metals / Substrate Specificity / Isoenzymes / Molecular Mass / Metal ion / Esterases / Ixodidae / Lipase / Diglycerides / Biochemistry and cell biology

Esterase and lipase in camel tick Hyalomma dromedarii (Acari: Ixodidae) during embryogenesis

Physiology / Kinetics / Enzyme Inhibitors / Animals / Camels / Egg Proteins / Enzyme / Metals / Substrate Specificity / Isoenzymes / Molecular Mass / Metal ion / Esterases / Ixodidae / Lipase / Diglycerides / Biochemistry and cell biology / Egg Proteins / Enzyme / Metals / Substrate Specificity / Isoenzymes / Molecular Mass / Metal ion / Esterases / Ixodidae / Lipase / Diglycerides / Biochemistry and cell biology

Intracoronary Ghrelin Infusion Decreases Coronary Blood Flow in Anesthetized Pigs

Endocrinology / Enzyme Inhibitors / Ghrelin / Biological Sciences / Nitric oxide / Animals / Heart rate / Vasoconstriction / Nitric Oxide Synthase / Swine / Coronary Circulation / Coronary Blood Flow / Coronary Artery Disease / Peptide hormones / Atropine / Methyl Ester / Animals / Heart rate / Vasoconstriction / Nitric Oxide Synthase / Swine / Coronary Circulation / Coronary Blood Flow / Coronary Artery Disease / Peptide hormones / Atropine / Methyl Ester

Recombinant Plasmepsin 1 from the Human Malaria Parasite Plasmodium falciparum : Enzymatic Characterization, Active Site Inhibitor Design, and Structural Analysis

Biochemistry / Catalysis / Kinetics / Enzyme Inhibitors / Humans / Animals / Structure Analysis / Solubility / Active site / Substrate Specificity / Plasmodium falciparum / Protozoan Proteins / Amino Acid Sequence / Amino Acid Substitution Rates / Structure activity Relationship / Recombinant Proteins / Hydrogen-Ion Concentration / Biochemistry and cell biology / Molecular Structure / Molecular Sequence Data / Animals / Structure Analysis / Solubility / Active site / Substrate Specificity / Plasmodium falciparum / Protozoan Proteins / Amino Acid Sequence / Amino Acid Substitution Rates / Structure activity Relationship / Recombinant Proteins / Hydrogen-Ion Concentration / Biochemistry and cell biology / Molecular Structure / Molecular Sequence Data

HaRas activates the NADPH oxidase complex in human neuroblastoma cells via extracellular signal-regulated kinase 1/2 pathway

Neurochemistry / Enzyme Inhibitors / Signal Transduction / Humans / Reactive Oxygen Species / Phosphorylation / Mitogen Activated Protein Kinase / NADPH oxidase / Neuroblastoma / Transfection / Amino Acid Substitution Rates / Neurosciences / Oxidation-Reduction / Superoxides / Protein Transport / Cell Membrane / Phosphorylation / Mitogen Activated Protein Kinase / NADPH oxidase / Neuroblastoma / Transfection / Amino Acid Substitution Rates / Neurosciences / Oxidation-Reduction / Superoxides / Protein Transport / Cell Membrane

HaRas activates the NADPH oxidase complex in human neuroblastoma cells via extracellular signal-regulated kinase 1/2 pathway

Neurochemistry / Enzyme Inhibitors / Signal Transduction / Humans / Reactive Oxygen Species / Phosphorylation / Mitogen Activated Protein Kinase / NADPH oxidase / Neuroblastoma / Transfection / Amino Acid Substitution Rates / Neurosciences / Oxidation-Reduction / Superoxides / Protein Transport / Cell Membrane / Phosphorylation / Mitogen Activated Protein Kinase / NADPH oxidase / Neuroblastoma / Transfection / Amino Acid Substitution Rates / Neurosciences / Oxidation-Reduction / Superoxides / Protein Transport / Cell Membrane

met oncogene activation qualifies spontaneous canine osteosarcoma as a suitable pre‐clinical model of human osteosarcoma

Pathology / Cancer / Immunohistochemistry / Enzyme Inhibitors / RNA interference / Dogs / Humans / Models / Animals / Osteosarcoma / The / Clinical Sciences / Neoplasm Invasiveness / Antineoplastic Agents / Receptor Tyrosine Kinase / Dogs / Humans / Models / Animals / Osteosarcoma / The / Clinical Sciences / Neoplasm Invasiveness / Antineoplastic Agents / Receptor Tyrosine Kinase

HaRas activates the NADPH oxidase complex in human neuroblastoma cells via extracellular signal-regulated kinase 1/2 pathway

Neurochemistry / Enzyme Inhibitors / Signal Transduction / Humans / Reactive Oxygen Species / Phosphorylation / Mitogen Activated Protein Kinase / NADPH oxidase / Neuroblastoma / Transfection / Amino Acid Substitution Rates / Neurosciences / Oxidation-Reduction / Superoxides / Protein Transport / Cell Membrane / Phosphorylation / Mitogen Activated Protein Kinase / NADPH oxidase / Neuroblastoma / Transfection / Amino Acid Substitution Rates / Neurosciences / Oxidation-Reduction / Superoxides / Protein Transport / Cell Membrane

Intramembrane proteolytic cleavage by human signal peptide peptidase like 3 and malaria signal peptide peptidase

Physiology / Membrane Proteins / Enzyme Inhibitors / Humans / Animals / Cell Death / Hepatitis C Virus / Medical Physiology / Molecular cloning / Active site / Plasmodium falciparum / Protozoan Proteins / MHC class I / Biochemistry and cell biology / Proteolytic activity / Cell Death / Hepatitis C Virus / Medical Physiology / Molecular cloning / Active site / Plasmodium falciparum / Protozoan Proteins / MHC class I / Biochemistry and cell biology / Proteolytic activity

Phenotypic Heterogeneity in Lung Capillary and Extra-Alveolar Endothelial Cells. Increased Extra-Alveolar Endothelial Permeability is Sufficient to Decrease Compliance

Enzyme Inhibitors / Endothelial Cells / Animals / Male / Acute respiratory distress syndrome / Carcinogens / Lung / Clinical Sciences / Rats / Endothelial cell / Surgical / Vascular Permeability / Respiratory Mechanics / Pulmonary Edema / Carcinogens / Lung / Clinical Sciences / Rats / Endothelial cell / Surgical / Vascular Permeability / Respiratory Mechanics / Pulmonary Edema

Mg-Dependent Ecto-ATPase Activity inLeishmania tropica

Calcium / Enzyme Inhibitors / Magnesium / Animals / Organophosphorus Compounds / Alkaline phosphatase / Enzyme / Substrate Specificity / Reaction Rate / Hydrogen-Ion Concentration / Nucleotides / Biochemistry and cell biology / Leishmania Tropica / Adenosine Triphosphate / Alkaline phosphatase / Enzyme / Substrate Specificity / Reaction Rate / Hydrogen-Ion Concentration / Nucleotides / Biochemistry and cell biology / Leishmania Tropica / Adenosine Triphosphate

Giardia lamblia: Characterization of ecto-phosphatase activities

Microbiology / Enzyme Inhibitors / Experimental parasitology / Animals / Molybdenum / Experimental / Substrate Specificity / Amino Acid Profile / Veterinary Sciences / Hydrogen-Ion Concentration / Sodium Fluoride / Experimental / Substrate Specificity / Amino Acid Profile / Veterinary Sciences / Hydrogen-Ion Concentration / Sodium Fluoride

A novel plant peptidyl-prolyl-cis-trans-isomerase (PPIase): cDNA cloning, structural analysis, enzymatic activity and expression

Genetics / Plant Biology / Enzyme Inhibitors / Plant Molecular Biology / Tacrolimus / Escherichia coli / Structure Analysis / Molecular cloning / Seeds / Calmodulin / Amino Acid Profile / Heat Shock Proteins / Amino Acid Sequence / Open Reading Frame / Triticum / Gene Family / Protein Binding / Embryos / Enzymatic Activity / Sirolimus / DNA binding proteins / Binding Site / Biochemistry and cell biology / Escherichia coli / Structure Analysis / Molecular cloning / Seeds / Calmodulin / Amino Acid Profile / Heat Shock Proteins / Amino Acid Sequence / Open Reading Frame / Triticum / Gene Family / Protein Binding / Embryos / Enzymatic Activity / Sirolimus / DNA binding proteins / Binding Site / Biochemistry and cell biology

Dynasore, a dynamin inhibitor, inhibits Trypanosoma cruzi entry into peritoneal macrophages

Engineering / Physics / Chemistry / Electron Microscopy / Biology / Scanning Electron Microscopy / Enzyme Inhibitors / Medicine / Multidisciplinary / Cell line / Endocytosis / Animals / PLoS one / Hydrazones / Trypanosoma Cruzi / Phagocytosis / Indexation / Plasma Membrane / Scanning Electron Microscopy / Enzyme Inhibitors / Medicine / Multidisciplinary / Cell line / Endocytosis / Animals / PLoS one / Hydrazones / Trypanosoma Cruzi / Phagocytosis / Indexation / Plasma Membrane
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