Enzyme Inhibitors - Page 5

Chemical Proteomics Discloses Petrosapongiolide M, an Antiinflammatory Marine Sesterterpene, as a Proteasome Inhibitor

Mass Spectrometry / Proteomics / Enzyme Inhibitors / Cell line / Humans / Anti-inflammatory agents / CHEMICAL SCIENCES / Protein Binding / Oleanolic acid / PROTEASOME INHIBITOR / Anti-inflammatory agents / CHEMICAL SCIENCES / Protein Binding / Oleanolic acid / PROTEASOME INHIBITOR

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Endogenous neurosteroids modulate epileptogenesis in a model of temporal lobe epilepsy

Psychology / Immunohistochemistry / Enzyme Inhibitors / STEROIDS / Hippocampus / Temporal Lobe / Animals / Male / Temporal Lobe Epilepsy / Glial Cell / Neurons / Enzyme / Clinical Sciences / Experimental / Rats / Pilocarpine / Time Factors / Finasteride / Experimental Neurology / Status Epilepticus / Neurosciences / Temporal Lobe / Animals / Male / Temporal Lobe Epilepsy / Glial Cell / Neurons / Enzyme / Clinical Sciences / Experimental / Rats / Pilocarpine / Time Factors / Finasteride / Experimental Neurology / Status Epilepticus / Neurosciences

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Increase in endoplasmic reticulum-associated tissue transglutaminase and enzymatic activation in a cellular model of Parkinson\'s disease

Neurobiology Of Disease / Drug interactions / Enzyme Inhibitors / Transmission Electron Microscopy / Neurobiology / Cell Differentiation / Humans / Endoplasmic Reticulum / Tunicamycin / ER stress / Neurons / Human Brain / Enzyme / Clinical Sciences / Neuroblastoma / Cellular Automaton Model / Degeneration / Retinoic Acid / Tretinoin / Membrane Protein / Enzymatic Activity / Cytoplasm / Neurosciences / Transglutaminases / Cell Differentiation / Humans / Endoplasmic Reticulum / Tunicamycin / ER stress / Neurons / Human Brain / Enzyme / Clinical Sciences / Neuroblastoma / Cellular Automaton Model / Degeneration / Retinoic Acid / Tretinoin / Membrane Protein / Enzymatic Activity / Cytoplasm / Neurosciences / Transglutaminases

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Gamma interferon-mediated superinduction of B7-H1 in PTEN-deficient glioblastoma: a paradoxical mechanism of immune evasion

Cognitive Science / Enzyme Inhibitors / Apoptosis / Signal Transduction / Humans / Glioblastoma / Immune Evasion / T lymphocytes / Lymphocytes / Antineoplastic Agents / Neurosciences / Brain Neoplasms / Interferon gamma / Glioblastoma / Immune Evasion / T lymphocytes / Lymphocytes / Antineoplastic Agents / Neurosciences / Brain Neoplasms / Interferon gamma

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Inhibition of Plasmepsin V Activity Demonstrates Its Essential Role in Protein Export, PfEMP1 Display, and Survival of Malaria Parasites

Microbiology / Medicinal Chemistry / Molecular Biology / Biology / Malaria / Enzyme Inhibitors / Public Health / Biological Sciences / Humans / Protease / Endoplasmic Reticulum / Host Parasite Interaction / Protozoan Proteins / Erythrocytes / Protein Transport / Enzyme Inhibitors / Public Health / Biological Sciences / Humans / Protease / Endoplasmic Reticulum / Host Parasite Interaction / Protozoan Proteins / Erythrocytes / Protein Transport

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Corallopyronin A Specifically Targets and Depletes Essential Obligate Wolbachia Endobacteria From Filarial Nematodes In Vivo

Symbiosis / Enzyme Inhibitors / Infectious Diseases / Biological Sciences / Cell line / Mice / Female / Animals / Bacteria / Wolbachia / Infectious / Filariasis / Molecular Conformation / Lactones / Aedes / Mice / Female / Animals / Bacteria / Wolbachia / Infectious / Filariasis / Molecular Conformation / Lactones / Aedes

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Gastric mucosal resistance to acute injury in experimental portal hypertension

Enzyme Inhibitors / Portal hypertension / Nitric oxide / Animals / Male / Anesthesia / Rats / Nitric Oxide Synthase / Isoenzymes / Prostaglandins / Portal vein / Anesthesia / Rats / Nitric Oxide Synthase / Isoenzymes / Prostaglandins / Portal vein

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Extracellular signal-regulated kinase and GEF-H1 mediate depolarization-induced Rho activation and paracellular permeability increase

Physiology / Calcium / Enzyme Inhibitors / Flavonoids / Dogs / Nitriles / Permeability / Animals / Potassium / Phosphorylation / Medical Physiology / Organophosphorus Compounds / Epithelial cells / Time Factors / Swine / Transfection / Alanine / Protein Kinase Inhibitors / Biochemistry and cell biology / Ouabain / Nitriles / Permeability / Animals / Potassium / Phosphorylation / Medical Physiology / Organophosphorus Compounds / Epithelial cells / Time Factors / Swine / Transfection / Alanine / Protein Kinase Inhibitors / Biochemistry and cell biology / Ouabain

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Transient Focal Ischemia Increases Endothelial Nitric Oxide Synthase in Cerebral Blood Vessels

Pathology / Microcirculation / Immunohistochemistry / Enzyme Inhibitors / Gene expression / Quantitative analysis / Western blotting / Pathophysiology / Stroke / Brain / Nitric oxide / Animals / Male / Parietal Cortex / Alkaline phosphatase / Clinical Sciences / Rats / Nitric Oxide Synthase / Parietal Lobe / Rat / Cerebral Ischemia / Blood Vessels / Wistar Rats / Quantitative Analysis / Neurosciences / Blood Vessel / Methyl Ester / Middle Cerebral Artery / Immunoblotting / Quantitative analysis / Western blotting / Pathophysiology / Stroke / Brain / Nitric oxide / Animals / Male / Parietal Cortex / Alkaline phosphatase / Clinical Sciences / Rats / Nitric Oxide Synthase / Parietal Lobe / Rat / Cerebral Ischemia / Blood Vessels / Wistar Rats / Quantitative Analysis / Neurosciences / Blood Vessel / Methyl Ester / Middle Cerebral Artery / Immunoblotting

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Inhibition of matrix metalloproteinase activity in vivo protects against vascular hyporeactivity in endotoxemia

Engineering / Chemical Engineering / Physiology / Nutrition and Dietetics / Food Science / Fear / Compliance / Cytokines / Neurobiology of Learning and Memory / Prostate Cancer / Enzyme Inhibitors / Mast Cells / Flavonoids / Dental Materials / Extracellular Matrix / Catheterization / Anxiety / Signal Transduction / Memory / Biological Sciences / Heart Failure / Classical Conditioning / Hearing / Humans / Protein Kinases / Hemodynamics / Mice / Cues / Female / Animals / Male / American / Fibrosis / Medical Physiology / Mitogen Activated Protein Kinase / Clinical Sciences / Nutritional Biochemistry / Rats / Myocardial Infarction / Myocardium / Protease Inhibitors / Public health systems and services research / Analysis of Variance / Time Factors / Vaccinium / Tumor necrosis factor-alpha / Circulation / Matrix Metalloproteinases / Food Sciences / ANXIETY / Hydroxyproline / Ventricular Remodeling / Somatic Cell Count / MAP Kinase / Aorta / Heart Ventricles / Hydroxamic Acids / Angiotensin Converting Enzyme Inhibitors / Catabolism / Biochemistry and cell biology / Adenocarcinoma / Captopril / Lisinopril / 4-Tetrahydroisoquinolines / Matrix Metalloproteinase / Electroshock / Fear / Compliance / Cytokines / Neurobiology of Learning and Memory / Prostate Cancer / Enzyme Inhibitors / Mast Cells / Flavonoids / Dental Materials / Extracellular Matrix / Catheterization / Anxiety / Signal Transduction / Memory / Biological Sciences / Heart Failure / Classical Conditioning / Hearing / Humans / Protein Kinases / Hemodynamics / Mice / Cues / Female / Animals / Male / American / Fibrosis / Medical Physiology / Mitogen Activated Protein Kinase / Clinical Sciences / Nutritional Biochemistry / Rats / Myocardial Infarction / Myocardium / Protease Inhibitors / Public health systems and services research / Analysis of Variance / Time Factors / Vaccinium / Tumor necrosis factor-alpha / Circulation / Matrix Metalloproteinases / Food Sciences / ANXIETY / Hydroxyproline / Ventricular Remodeling / Somatic Cell Count / MAP Kinase / Aorta / Heart Ventricles / Hydroxamic Acids / Angiotensin Converting Enzyme Inhibitors / Catabolism / Biochemistry and cell biology / Adenocarcinoma / Captopril / Lisinopril / 4-Tetrahydroisoquinolines / Matrix Metalloproteinase / Electroshock

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Bleomycin induces cellular senescence in alveolar epithelial cells

Regeneration / Immunohistochemistry / Enzyme Inhibitors / Cell line / Cell morphology / Interstitial Lung Disease / Pulmonary fibrosis / Mice / Animals / Lung / Rats / Epithelial cells / Time Dependent / Time Factors / Bleomycin / Cell Size / Immunoblotting / Interstitial Lung Disease / Pulmonary fibrosis / Mice / Animals / Lung / Rats / Epithelial cells / Time Dependent / Time Factors / Bleomycin / Cell Size / Immunoblotting

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Tryptophan 2,3-Dioxygenase (TDO) Inhibitors. 3-(2-(Pyridyl)ethenyl)indoles as Potential Anticancer Immunomodulators

Organic Chemistry / Medicinal Chemistry / Kinetics / Enzyme Inhibitors / Cell line / Humans / Mice / Animals / Drug Design / Medicinal / Neoplasms / Structure activity Relationship / Biological Availability / Antineoplastic Agents / Humans / Mice / Animals / Drug Design / Medicinal / Neoplasms / Structure activity Relationship / Biological Availability / Antineoplastic Agents

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Ku Entry into DNA Inhibits Inward DNA Transactions in Vitro

Enzyme Inhibitors / Biological Chemistry / DNA damage / DNA repair / Biological Sciences / DNA / Humans / Plasmids / CHEMICAL SCIENCES / HeLa cells / Base Sequence / Protein Binding / DNA binding proteins / Nucleic Acid Conformation / DNA / Humans / Plasmids / CHEMICAL SCIENCES / HeLa cells / Base Sequence / Protein Binding / DNA binding proteins / Nucleic Acid Conformation

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Lysyl oxidases play a causal role in vascular remodeling in clinical and experimental pulmonary arterial hypertension

Enzyme Inhibitors / Pulmonary Hypertension / Humans / Anoxia / Collagen / Mice / Female / Animals / Male / Young Adult / Clinical Sciences / Middle Aged / Elastin / Rats / Adult / Isoenzymes / Human Fibroblasts / Case Control Studies / Pulmonary Artery / Mice / Female / Animals / Male / Young Adult / Clinical Sciences / Middle Aged / Elastin / Rats / Adult / Isoenzymes / Human Fibroblasts / Case Control Studies / Pulmonary Artery

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Human Hydroxysteroid (17-β) Dehydrogenase 1 Expression Enhances Estrogen Sensitivity of MCF-7 Breast Cancer Cell Xenografts

Endocrinology / Enzyme Inhibitors / Biological Sciences / Humans / Mice / Female / Animals / Estrogens / Breast Cancer Cells / Estrogen receptor alpha / Female / Animals / Estrogens / Breast Cancer Cells / Estrogen receptor alpha

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Novel Hydroxysteroid (17β) Dehydrogenase 1 Inhibitors Reverse Estrogen-Induced Endometrial Hyperplasia in Transgenic Mice

Enzyme Inhibitors / Transgenic Mice / Humans / Mice / Female / Animals / American / Estrogens / Uterus / Progestins / Estradiol / Endometrial Hyperplasia / Animals / American / Estrogens / Uterus / Progestins / Estradiol / Endometrial Hyperplasia

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