Enzyme Inhibitors

Lifespan Extension in a Semelparous Chordate Occurs via Developmental Growth Arrest Just Prior to Meiotic Entry

Aging / Enzyme Inhibitors / Multidisciplinary / Signal Transduction / Longevity / Meiosis / Animals / PLoS one / Meiosis / Animals / PLoS one

Glucocorticoid Metabolism in Proximal Tubules Modulates Angiotensin II-Induced Electrolyte Transport

Enzyme Inhibitors / Animals / Corticosterone / Rats / Wistar Rats / Angiotensin II / Proximal Tubule / Glucocorticoids / Angiotensin II / Proximal Tubule / Glucocorticoids

Bitter melon juice activates cellular energy sensor AMP-activated protein kinase causing apoptotic death of human pancreatic carcinoma cells

Immunohistochemistry / Enzyme Inhibitors / Apoptosis / Humans / Protein Kinases / Mice / Animals / Male / Caspase / Carcinogenesis / Plant extracts / Momordica / Cell Proliferation / Cell Survival / Enzyme Linked Immunosorbent Assay / Mice / Animals / Male / Caspase / Carcinogenesis / Plant extracts / Momordica / Cell Proliferation / Cell Survival / Enzyme Linked Immunosorbent Assay

Cholesterol-3-beta, 5-alpha, 6-beta-triol induced PI(3)K-Akt-eNOS-dependent cyclooxygenase-2 expression in endothelial cells

RNA / Enzyme Inhibitors / Gene expression / Western blotting / Humans / Endothelial Cells / Cholesterol / Nitric oxide / NF-kappa B / mRna expression levels / Time Dependent / Endothelial cell / Protein Expression / Protein Phosphorylation / Chromones / Cell Survival / Endothelial Cells / Cholesterol / Nitric oxide / NF-kappa B / mRna expression levels / Time Dependent / Endothelial cell / Protein Expression / Protein Phosphorylation / Chromones / Cell Survival

Extracellular signal-regulated kinase and GEF-H1 mediate depolarization-induced Rho activation and paracellular permeability increase

Physiology / Calcium / Enzyme Inhibitors / Flavonoids / Dogs / Nitriles / Permeability / Animals / Potassium / Phosphorylation / Medical Physiology / Organophosphorus Compounds / Epithelial cells / Time Factors / Swine / Transfection / Alanine / Protein Kinase Inhibitors / Biochemistry and cell biology / Ouabain / Nitriles / Permeability / Animals / Potassium / Phosphorylation / Medical Physiology / Organophosphorus Compounds / Epithelial cells / Time Factors / Swine / Transfection / Alanine / Protein Kinase Inhibitors / Biochemistry and cell biology / Ouabain

Differential inhibition of mesangial MAP kinase cascade by cyclic nucleotides

Enzyme Inhibitors / Signal Transduction / Protein Kinases / Kidney / cyclic AMP / Animals / Peptides / Mitogen Activated Protein Kinase / Clinical Sciences / Rats / Cyclic nucleotides / Endothelin-1 / MAP Kinase / cyclic GMP / Animals / Peptides / Mitogen Activated Protein Kinase / Clinical Sciences / Rats / Cyclic nucleotides / Endothelin-1 / MAP Kinase / cyclic GMP

Cyclic nucleotide phosphodiesterase 3A–deficient mice as a model of female infertility

Enzyme Inhibitors / Humans / Meiosis / Mice / cyclic AMP / Female / Ovulation / Animals / Clinical / Phosphodiesterase Inhibitors / Isoenzymes / Cyclic nucleotides / Ovary / Oocytes / Female Infertility / Clinical Investigation / Female / Ovulation / Animals / Clinical / Phosphodiesterase Inhibitors / Isoenzymes / Cyclic nucleotides / Ovary / Oocytes / Female Infertility / Clinical Investigation

Inhibition of Plasmepsin V Activity Demonstrates Its Essential Role in Protein Export, PfEMP1 Display, and Survival of Malaria Parasites

Microbiology / Medicinal Chemistry / Molecular Biology / Biology / Malaria / Enzyme Inhibitors / Public Health / Biological Sciences / Humans / Protease / Endoplasmic Reticulum / Host Parasite Interaction / Protozoan Proteins / Erythrocytes / Protein Transport / Enzyme Inhibitors / Public Health / Biological Sciences / Humans / Protease / Endoplasmic Reticulum / Host Parasite Interaction / Protozoan Proteins / Erythrocytes / Protein Transport

Propecia-induced spermatogenic failure: a report of two cases

Enzyme Inhibitors / Humans / Fertility and Sterility / Male / Azoospermia / Clinical Sciences / Adult / Public health systems and services research / Finasteride / Clinical Sciences / Adult / Public health systems and services research / Finasteride

Peptide inhibitors of N-succinyl diaminopimelic acid aminotransferase (DAP-AT): A novel class of antimicrobial compounds

Organic Chemistry / Kinetics / Enzyme Inhibitors / Escherichia coli / Anti-Bacterial Agents / Substrate Specificity / Bioorganic and medicinal Chemistry / Structure activity Relationship / Glutamate Dehydrogenase / Molecular Structure / Transaminases / Substrate Specificity / Bioorganic and medicinal Chemistry / Structure activity Relationship / Glutamate Dehydrogenase / Molecular Structure / Transaminases

Pyrazolopyrimidines Establish MurC as a Vulnerable Target in Pseudomonas aeruginosa and Escherichia coli

Enzyme Inhibitors / Biological Sciences / Humans / Protein Kinases / Escherichia coli / Pseudomonas aeruginosa / CHEMICAL SCIENCES / Anti-Bacterial Agents / Microbial Sensitivity Tests / Pseudomonas Aeruginosa / Alanine / Pyrazoles / Structure activity Relationship / Molecular Structure / Pseudomonas aeruginosa / CHEMICAL SCIENCES / Anti-Bacterial Agents / Microbial Sensitivity Tests / Pseudomonas Aeruginosa / Alanine / Pyrazoles / Structure activity Relationship / Molecular Structure

Chemical genetics identifies Rab geranylgeranyl transferase as an apoptotic target of farnesyl transferase inhibitors

Genetics / Caenorhabditis elegans / Enzyme Inhibitors / Apoptosis / Gene expression / Caspases / RNA interference / Humans / Germ Cells / Mutagenesis / Animals / Neoplasms / Cancer Cell / Calcium Binding Proteins / Antineoplastic Agents / Neurosciences / Caspases / RNA interference / Humans / Germ Cells / Mutagenesis / Animals / Neoplasms / Cancer Cell / Calcium Binding Proteins / Antineoplastic Agents / Neurosciences

Symmetric adamantyl-diureas as soluble epoxide hydrolase inhibitors

Organic Chemistry / Enzyme Inhibitors / Humans / Urea / Adamantane

Förster resonance energy transfer competitive displacement assay for human soluble epoxide hydrolase

Analytical Chemistry / Fluorescence / Enzyme Inhibitors / Macromolecular X-Ray Crystallography / Fluorescence Resonance Energy Transfer / Humans / Tryptophan / Solubility / Analytical Biochemistry / Biological Assay / Biochemistry and cell biology / Humans / Tryptophan / Solubility / Analytical Biochemistry / Biological Assay / Biochemistry and cell biology

Transrepression of Estrogen Receptor β Signaling by Nuclear Factor-κB in Ovarian Granulosa Cells

Enzyme Inhibitors / Molecular endocrinology / Signal Transduction / Estrogen Receptor / Biological Sciences / Cell line / Humans / Female / Animals / NF-kappa B / Estrogens / Glucocorticoids / Response Elements / Estrogen receptor-beta / Estrogen receptor alpha / Cell line / Humans / Female / Animals / NF-kappa B / Estrogens / Glucocorticoids / Response Elements / Estrogen receptor-beta / Estrogen receptor alpha

Transrepression of estrogen receptor beta signaling by nuclear factor-kappab in ovarian granulosa cells

Enzyme Inhibitors / Molecular endocrinology / Signal Transduction / Estrogen Receptor / Biological Sciences / Cell line / Humans / Female / Animals / NF-kappa B / Estrogens / Glucocorticoids / Response Elements / Estrogen receptor-beta / Estrogen receptor alpha / Cell line / Humans / Female / Animals / NF-kappa B / Estrogens / Glucocorticoids / Response Elements / Estrogen receptor-beta / Estrogen receptor alpha

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