Enzyme Inhibitors

Adenine phosphoribosyltransferase deficiency in children

Kidney diseases / Enzyme Inhibitors / Adolescent / Humans / Child / Female / Animals / Inborn errors of metabolism / Male / Young Adult / Infant / Pediatric Nephrology / Pediatric / Phenotype / Recurrence / Clinical Sciences / Urolithiasis / Retrospective Studies / Prognosis / Biological markers / Disease Progression / Adenine / Allopurinol / Predictive value of tests / Female / Animals / Inborn errors of metabolism / Male / Young Adult / Infant / Pediatric Nephrology / Pediatric / Phenotype / Recurrence / Clinical Sciences / Urolithiasis / Retrospective Studies / Prognosis / Biological markers / Disease Progression / Adenine / Allopurinol / Predictive value of tests

A lepidopteran pacifastin member: Cloning, gene structure, recombinant production, transcript profiling and in vitro activity

Zoology / Enzyme Inhibitors / Fungi / Gene expression / Sequence alignment / Escherichia coli / Animals / Proteins / Gene Structure / Enzyme / Molecular cloning / Insect Biochemistry and Molecular Biology / Amino Acid Sequence / Molecular Identification / Recombinant Proteins / Entomopathogenic Fungi / Insect Biochemistry / Biochemistry and cell biology / Bombyx mori / Escherichia coli / Animals / Proteins / Gene Structure / Enzyme / Molecular cloning / Insect Biochemistry and Molecular Biology / Amino Acid Sequence / Molecular Identification / Recombinant Proteins / Entomopathogenic Fungi / Insect Biochemistry / Biochemistry and cell biology / Bombyx mori

Ceramide kinase deficiency impairs microendothelial cell angiogenesis in vitro

Enzyme Inhibitors / Signal Transduction / Microvascular Physiology / Capillaries / Mice / Animals / Vascular endothelium / Fibroblast Growth Factor / Clinical Sciences / Endothelial cell / Dermis / Cell Proliferation / Tumor Necrosis Factor–α (TNF) / Sphingosine 1-phosphate / Ceramides / Vascular Endothelial Growth Factor / Animals / Vascular endothelium / Fibroblast Growth Factor / Clinical Sciences / Endothelial cell / Dermis / Cell Proliferation / Tumor Necrosis Factor–α (TNF) / Sphingosine 1-phosphate / Ceramides / Vascular Endothelial Growth Factor

Vascular endothelial growth factor production in polymyalgia rheumatica

Immunology / Calcium / Immunohistochemistry / Enzyme Inhibitors / Vascular biology / Hepatology / Biological Sciences / Cell line / Thrombin / Pregnancy / Humans / Glioma / Female / Animals / Calcium Signaling / Arthritis / Lung / Mitogen Activated Protein Kinase / Integrins / Clinical Sciences / Human reproduction / Rats / Adult / Public health systems and services research / Western blot / Transforming Growth Factor Beta / Protein isoforms / Human Fibroblasts / MAP Kinase / Recombinant Proteins / Polymyalgia Rheumatica / Tissue Factor / Gangliosides / Factor Xa / Vascular Endothelial Growth Factor / Biology Reproduction / Intracellular Calcium / Isomerism / Hepatology / Biological Sciences / Cell line / Thrombin / Pregnancy / Humans / Glioma / Female / Animals / Calcium Signaling / Arthritis / Lung / Mitogen Activated Protein Kinase / Integrins / Clinical Sciences / Human reproduction / Rats / Adult / Public health systems and services research / Western blot / Transforming Growth Factor Beta / Protein isoforms / Human Fibroblasts / MAP Kinase / Recombinant Proteins / Polymyalgia Rheumatica / Tissue Factor / Gangliosides / Factor Xa / Vascular Endothelial Growth Factor / Biology Reproduction / Intracellular Calcium / Isomerism

Purification, Characterization and Partial Amino Acid Sequencing of Hydroxycinnamoyl-CoA: Tyramine N-(hydroxycinnamoyl)transferase from Tobacco Cell-Suspension Cultures

Engineering / Biochemistry / Technology / Chromatography / Kinetics / Hydroxyapatite / Tobacco / Calcium / Enzyme Inhibitors / Biological Chemistry / Snake venoms / Western blotting / Biological Sciences / Humans / Sequence alignment / Liver / Circular Dichroism / Animals / Male / Anura / Plants / Rat Brain / Trypsin / Proteins / Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis / Organophosphorus Compounds / tESTIS / High Pressure Liquid Chromatography / Goats / CHEMICAL SCIENCES / European / Amino Acids / Rats / Guanosine Triphosphate / Substrate Specificity / Cooperativity / Molecular Mass / Molecular weight / Nerve Growth Factor / Hydroxyapatites / Amino Acid Sequence / Durapatite / Hydrogen-Ion Concentration / PLANT PROTEINS / Binding Site / Conformational Change / Gtp Binding Proteins / Molecular and Cellular Biochemistry / Biochemistry and cell biology / Cell Suspension Culture / Ouabain / Ammonium Sulphate / Hydroxyapatite / Tobacco / Calcium / Enzyme Inhibitors / Biological Chemistry / Snake venoms / Western blotting / Biological Sciences / Humans / Sequence alignment / Liver / Circular Dichroism / Animals / Male / Anura / Plants / Rat Brain / Trypsin / Proteins / Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis / Organophosphorus Compounds / tESTIS / High Pressure Liquid Chromatography / Goats / CHEMICAL SCIENCES / European / Amino Acids / Rats / Guanosine Triphosphate / Substrate Specificity / Cooperativity / Molecular Mass / Molecular weight / Nerve Growth Factor / Hydroxyapatites / Amino Acid Sequence / Durapatite / Hydrogen-Ion Concentration / PLANT PROTEINS / Binding Site / Conformational Change / Gtp Binding Proteins / Molecular and Cellular Biochemistry / Biochemistry and cell biology / Cell Suspension Culture / Ouabain / Ammonium Sulphate

Synthesis and biological evaluation of unprecedented classes of spiro-β-lactams and azido-β-lactams as acyl-CoA:cholesterol acyltransferase inhibitors

Organic Chemistry / Catalysis / Kinetics / Enzyme Inhibitors / Pharmaceutical Chemistry / Humans / Cholesterol / Drug Design / Absorption / Beta Lactams / Molecular Conformation / Bioorganic and medicinal Chemistry / Humans / Cholesterol / Drug Design / Absorption / Beta Lactams / Molecular Conformation / Bioorganic and medicinal Chemistry

Case 11-2013

Pain / Magnetic Resonance Imaging / Atherosclerosis / Prostate Cancer / Enzyme Inhibitors / Adolescent / England / Movement disorders / Spleen / Pregnancy / Humans / Liver / Placenta / Ischemia / Septic Shock / Weight Loss / Female / Renal cell Carcinoma / Male / Cytomegalovirus / Anemia / Thrombocytopenia / Streptococcus Pyogenes / Prostate / Differential Diagnosis / Diabetic Foot / Levodopa / Dystonia / Osteomyelitis / Leg Ulcer / Newborn Infant / Aged / Middle Aged / Anti-Bacterial Agents / Adult / Fever / New England / Leg / Prognosis / Hand / Hypotension / Finasteride / Pressure Ulcer / Cytomegalovirus Infections / Calciphylaxis / Clindamycin / Type 2 Diabetes Mellitus / X ray Computed Tomography / Abscess / Urinary retention / New England Journalof Medicine / Renal disease / Abdominal Pain / Prostate Specific Antigen / Nephrectomy / Acute Appendicitis / Right Handed / Cellulitis / Adolescent / England / Movement disorders / Spleen / Pregnancy / Humans / Liver / Placenta / Ischemia / Septic Shock / Weight Loss / Female / Renal cell Carcinoma / Male / Cytomegalovirus / Anemia / Thrombocytopenia / Streptococcus Pyogenes / Prostate / Differential Diagnosis / Diabetic Foot / Levodopa / Dystonia / Osteomyelitis / Leg Ulcer / Newborn Infant / Aged / Middle Aged / Anti-Bacterial Agents / Adult / Fever / New England / Leg / Prognosis / Hand / Hypotension / Finasteride / Pressure Ulcer / Cytomegalovirus Infections / Calciphylaxis / Clindamycin / Type 2 Diabetes Mellitus / X ray Computed Tomography / Abscess / Urinary retention / New England Journalof Medicine / Renal disease / Abdominal Pain / Prostate Specific Antigen / Nephrectomy / Acute Appendicitis / Right Handed / Cellulitis

Extracellular purines from cells of seminiferous tubules

Kinetics / Enzyme Inhibitors / Male Reproduction Health / Adenosine / Molecular and cellular biology / Germ Cells / Animals / Male / Sertoli cells / Phosphodiesterase Inhibitors / Rats / Wistar Rats / Sertoli Cell / Adenine / Extracellular Space / Germ Cell / Molecular and Cellular Biochemistry / Nucleotides / Biochemistry and cell biology / Adenosine Triphosphate / Adenosine Diphosphate / Seminiferous tubules / Germ Cells / Animals / Male / Sertoli cells / Phosphodiesterase Inhibitors / Rats / Wistar Rats / Sertoli Cell / Adenine / Extracellular Space / Germ Cell / Molecular and Cellular Biochemistry / Nucleotides / Biochemistry and cell biology / Adenosine Triphosphate / Adenosine Diphosphate / Seminiferous tubules

Efficacy of Proveblue (Methylene Blue) in an Experimental Cerebral Malaria Murine Model

Microbiology / Medical Microbiology / Enzyme Inhibitors / Mice / Female / Animals / Methylene Blue / Antimalarials / Combination drug therapy / Cerebral Malaria / Plasmodium berghei / Animals / Methylene Blue / Antimalarials / Combination drug therapy / Cerebral Malaria / Plasmodium berghei

Plasma concentration of myeloperoxidase enzyme in pre- and post-climacterial people: related superoxide anion generation

Enzyme Inhibitors / Cardiovascular Risk / Free Radical / Peroxidase / Humans / Testosterone / Female / Male / Enzyme / Aged / Middle Aged / Neutrophils / Experimental / Older Women / Adult / Sterols / Superoxide Anion / Myeloperoxidase / Superoxides / aniline Compounds / Indomethacin / Testosterone / Female / Male / Enzyme / Aged / Middle Aged / Neutrophils / Experimental / Older Women / Adult / Sterols / Superoxide Anion / Myeloperoxidase / Superoxides / aniline Compounds / Indomethacin

Chemical genetics identifies Rab geranylgeranyl transferase as an apoptotic target of farnesyl transferase inhibitors

Genetics / Caenorhabditis elegans / Enzyme Inhibitors / Apoptosis / Gene expression / Caspases / RNA interference / Humans / Germ Cells / Mutagenesis / Animals / Neoplasms / Cancer Cell / Calcium Binding Proteins / Antineoplastic Agents / Neurosciences / Caspases / RNA interference / Humans / Germ Cells / Mutagenesis / Animals / Neoplasms / Cancer Cell / Calcium Binding Proteins / Antineoplastic Agents / Neurosciences

3-Aminobenzamide, a Poly ADP Ribose Polymerase Inhibitor, Attenuates Renal Ischemia/Reperfusion Injury

Nonparametric Statistics / Immunohistochemistry / Enzyme Inhibitors / Oxidative Stress / Probability / Ischemia Reperfusion Injury / Animals / Renal failure / Male / Blood Urea Nitrogen / Clinical Sciences / Rats / Renal / Reperfusion injury / Creatinine / Benzamides / Ischemia Reperfusion Injury / Animals / Renal failure / Male / Blood Urea Nitrogen / Clinical Sciences / Rats / Renal / Reperfusion injury / Creatinine / Benzamides

3-Aminobenzamide, a Poly ADP Ribose Polymerase Inhibitor, Attenuates Renal Ischemia/Reperfusion Injury

Nonparametric Statistics / Immunohistochemistry / Enzyme Inhibitors / Oxidative Stress / Probability / Ischemia Reperfusion Injury / Animals / Renal failure / Male / Blood Urea Nitrogen / Clinical Sciences / Rats / Renal / Reperfusion injury / Creatinine / Benzamides / Ischemia Reperfusion Injury / Animals / Renal failure / Male / Blood Urea Nitrogen / Clinical Sciences / Rats / Renal / Reperfusion injury / Creatinine / Benzamides

Case 11-2013

Pain / Magnetic Resonance Imaging / Atherosclerosis / Prostate Cancer / Enzyme Inhibitors / Adolescent / England / Movement disorders / Spleen / Pregnancy / Humans / Liver / Placenta / Ischemia / Septic Shock / Weight Loss / Female / Renal cell Carcinoma / Male / Cytomegalovirus / Anemia / Thrombocytopenia / Streptococcus Pyogenes / Prostate / Differential Diagnosis / Diabetic Foot / Levodopa / Dystonia / Osteomyelitis / Leg Ulcer / Newborn Infant / Aged / Middle Aged / Anti-Bacterial Agents / Adult / Fever / New England / Leg / Prognosis / Hand / Hypotension / Finasteride / Pressure Ulcer / Cytomegalovirus Infections / Calciphylaxis / Clindamycin / Type 2 Diabetes Mellitus / X ray Computed Tomography / Abscess / Urinary retention / New England Journalof Medicine / Renal disease / Abdominal Pain / Prostate Specific Antigen / Nephrectomy / Acute Appendicitis / Right Handed / Cellulitis / Adolescent / England / Movement disorders / Spleen / Pregnancy / Humans / Liver / Placenta / Ischemia / Septic Shock / Weight Loss / Female / Renal cell Carcinoma / Male / Cytomegalovirus / Anemia / Thrombocytopenia / Streptococcus Pyogenes / Prostate / Differential Diagnosis / Diabetic Foot / Levodopa / Dystonia / Osteomyelitis / Leg Ulcer / Newborn Infant / Aged / Middle Aged / Anti-Bacterial Agents / Adult / Fever / New England / Leg / Prognosis / Hand / Hypotension / Finasteride / Pressure Ulcer / Cytomegalovirus Infections / Calciphylaxis / Clindamycin / Type 2 Diabetes Mellitus / X ray Computed Tomography / Abscess / Urinary retention / New England Journalof Medicine / Renal disease / Abdominal Pain / Prostate Specific Antigen / Nephrectomy / Acute Appendicitis / Right Handed / Cellulitis

Extracellular Matrix Rigidity Promotes Invadopodia Activity

Enzyme Inhibitors / Extracellular Matrix / Signal Transduction / Biological Sciences / Humans / Gelatin / Actin Cytoskeleton / Integrins / Focal Adhesion Kinase / Gelatin / Actin Cytoskeleton / Integrins / Focal Adhesion Kinase

Inhibitory activity of 6-O-angeloylprenolin fromCentipeda minima on farnesyl protein transferase

Enzyme Inhibitors / Magnetic Resonance Spectroscopy / Methanol / Asteraceae / Affinity chromatography / Sesquiterpenes / High Pressure Liquid Chromatography / Plant extracts / Quntitative Thin Layer Chromatography / Lactones / Solvents / Sesquiterpenes / High Pressure Liquid Chromatography / Plant extracts / Quntitative Thin Layer Chromatography / Lactones / Solvents
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