Enzyme Inhibitors

Oligonucleotide N3′→P5′ phosphoramidates as efficient telomerase inhibitors

Enzyme Inhibitors / Cell Division / Telomerase / Cell line / Humans / Female / Oncogene / Enzyme / Clinical Sciences / Amides / Telomere / Cell Proliferation / Reverse Transcriptase / Antineoplastic Agents / Oligonucleotides / Oligonucleotide / Female / Oncogene / Enzyme / Clinical Sciences / Amides / Telomere / Cell Proliferation / Reverse Transcriptase / Antineoplastic Agents / Oligonucleotides / Oligonucleotide

Intra-arterial AICA-riboside administration induces NO-dependent vasodilation in vivo in human skeletal muscle

Skeletal muscle biology / Enzyme Inhibitors / Biological Sciences / Ischemia Reperfusion Injury / Humans / Caffeine / Hemodynamics / Nitric oxide / Female / Male / Young Adult / American / Animal Model / In Vivo / Skeletal Muscle / Adult / Blood Flow / Free Fatty Acid / Vasodilatation / Glucose Uptake / Vasodilation / Healthy Subjects / Forearm / Brachial artery / Caffeine / Hemodynamics / Nitric oxide / Female / Male / Young Adult / American / Animal Model / In Vivo / Skeletal Muscle / Adult / Blood Flow / Free Fatty Acid / Vasodilatation / Glucose Uptake / Vasodilation / Healthy Subjects / Forearm / Brachial artery

Protein kinaseCδ-calmodulin crosstalk regulates epidermal growth factor receptor exit from early endosomes

Molecular Biology / Fluorescence Microscopy / Enzyme Inhibitors / Confocal Microscopy / Western blotting / Biological Sciences / Humans / Mice / Endocytosis / Animals / Temperature / Mitogen Activated Protein Kinase / Epidermal Growth Factor Receptor / Time Factors / HeLa cells / Calmodulin / Transfection / Protein isoforms / Subcellular Fractions / Endosomes / Protein Transport / Gene Expression Regulation / Down-Regulation / Biological Sciences / Humans / Mice / Endocytosis / Animals / Temperature / Mitogen Activated Protein Kinase / Epidermal Growth Factor Receptor / Time Factors / HeLa cells / Calmodulin / Transfection / Protein isoforms / Subcellular Fractions / Endosomes / Protein Transport / Gene Expression Regulation / Down-Regulation

Protein kinaseCdelta-calmodulin crosstalk regulates epidermal growth factor receptor exit from early endosomes

Molecular Biology / Fluorescence Microscopy / Enzyme Inhibitors / Confocal Microscopy / Western blotting / Biological Sciences / Humans / Mice / Endocytosis / Animals / Temperature / Mitogen Activated Protein Kinase / Epidermal Growth Factor Receptor / Time Factors / HeLa cells / Calmodulin / Transfection / Protein isoforms / Subcellular Fractions / Endosomes / Protein Transport / Gene Expression Regulation / Down-Regulation / Biological Sciences / Humans / Mice / Endocytosis / Animals / Temperature / Mitogen Activated Protein Kinase / Epidermal Growth Factor Receptor / Time Factors / HeLa cells / Calmodulin / Transfection / Protein isoforms / Subcellular Fractions / Endosomes / Protein Transport / Gene Expression Regulation / Down-Regulation

The Clinical Phenotype of Succinic Semialdehyde Dehydrogenase Deficiency (4-Hydroxybutyric Aciduria): Case Reports of 23 New Patients

Pediatrics / Enzyme Inhibitors / Adolescent / Intellectual Disability / Case Report / Humans / Child / Female / Inborn errors of metabolism / Male / Infant / Developmental disabilities / Differential Diagnosis / Adult / Vigabatrin / Gamma-Aminobutyric Acid / Motor Skills / Humans / Child / Female / Inborn errors of metabolism / Male / Infant / Developmental disabilities / Differential Diagnosis / Adult / Vigabatrin / Gamma-Aminobutyric Acid / Motor Skills

Cytotoxic Prenylxanthones from Garcinia bracteata

Natural Products / Mass Spectrometry / Enzyme Inhibitors / Medicinal Plants / Magnetic Resonance Spectroscopy / Macromolecular X-Ray Crystallography / Biological Sciences / Humans / CHEMICAL SCIENCES / Natural / KB cells / Plant Leaves / Macromolecular X-Ray Crystallography / Biological Sciences / Humans / CHEMICAL SCIENCES / Natural / KB cells / Plant Leaves

Mitochondrial arginase II constrains endothelial NOS-3 activity

Physiology / Enzyme Inhibitors / Mitochondria / Elasticity / Endothelial Cells / Mice / Nitric oxide / Animals / Male / American / Acetylcholine / Medical Physiology / Vasoconstriction / Phenylephrine / Aorta / Vasodilation / Pulsatile Flow / Mice / Nitric oxide / Animals / Male / American / Acetylcholine / Medical Physiology / Vasoconstriction / Phenylephrine / Aorta / Vasodilation / Pulsatile Flow

Plasma concentration of myeloperoxidase enzyme in pre- and post-climacterial people: related superoxide anion generation

Enzyme Inhibitors / Cardiovascular Risk / Free Radical / Peroxidase / Humans / Testosterone / Female / Male / Enzyme / Aged / Middle Aged / Neutrophils / Experimental / Older Women / Adult / Sterols / Superoxide Anion / Myeloperoxidase / Superoxides / aniline Compounds / Indomethacin / Testosterone / Female / Male / Enzyme / Aged / Middle Aged / Neutrophils / Experimental / Older Women / Adult / Sterols / Superoxide Anion / Myeloperoxidase / Superoxides / aniline Compounds / Indomethacin

The Inhaled Glucocorticoid Fluticasone Propionate Efficiently Inactivates Cytochrome P450 3A5, a Predominant Lung P450 Enzyme

Inorganic Chemistry / Organic Chemistry / Enzyme Inhibitors / Humans / Lung / Enzyme / Time Factors / Structure activity Relationship / Recombinant Proteins / Food and Chemical Toxicology / Glucocorticoids / Fluticasone propionate / Enzyme / Time Factors / Structure activity Relationship / Recombinant Proteins / Food and Chemical Toxicology / Glucocorticoids / Fluticasone propionate

MD-2 controls bacterial lipopolysaccharide hyporesponsiveness in human intestinal epithelial cells

Immune response / Flow Cytometry / Life Sciences / Enzyme Inhibitors / Gene expression / Toll like receptor signaling / Lipopolysaccharide / Humans / NF-kappa B / Intestines / Caco-2 cells / Gram-negative bacteria / Lipopolysaccharides / Epithelial cells / Monocytes / Pyridines / Transfection / Imidazoles / Prostaglandin E2 / Biochemistry and cell biology / Interleukin / Toll like receptor signaling / Lipopolysaccharide / Humans / NF-kappa B / Intestines / Caco-2 cells / Gram-negative bacteria / Lipopolysaccharides / Epithelial cells / Monocytes / Pyridines / Transfection / Imidazoles / Prostaglandin E2 / Biochemistry and cell biology / Interleukin

Anti-hepatitis C virus activity of Acacia confusa extract via suppressing cyclooxygenase-2

Medical Microbiology / Enzyme Inhibitors / Humans / Hepatocellular Carcinoma / Hepatitis C Virus / Selection Index / Acacia / Plant extracts / Antiviral / Nuclear Factor-kappaB / Logistic Model / chronic hepatitis C / Antiviral Agents / Interferon Alpha / Selection Index / Acacia / Plant extracts / Antiviral / Nuclear Factor-kappaB / Logistic Model / chronic hepatitis C / Antiviral Agents / Interferon Alpha

How does cyanide inhibit superoxide reductase? Insight from synthetic FeIIIN4S model complexes

Enzyme Inhibitors / Multidisciplinary / Oxidoreductases / Molecular Conformation / Cyanides / Model Complexity / Ligands / Ferric Compounds / Model Complexity / Ligands / Ferric Compounds

Unusual location and characterization of Cu/Zn-containing superoxide dismutase from filamentous fungus Humicola lutea

Microbiology / Medical Microbiology / Archives / Enzyme Inhibitors / Mitochondria / Western blotting / Cell Fractionation / Superoxide Dismutase / Enzyme / Glycosylation / Protein Sequence Analysis / Model System / Filamentous fungi / Enzyme activity / Molecular Mass / Molecular weight / Amino Acid Sequence / Ascomycota / Superoxide Anion / Electrophoretic Mobility / Western blotting / Cell Fractionation / Superoxide Dismutase / Enzyme / Glycosylation / Protein Sequence Analysis / Model System / Filamentous fungi / Enzyme activity / Molecular Mass / Molecular weight / Amino Acid Sequence / Ascomycota / Superoxide Anion / Electrophoretic Mobility

Classifying Molecules Using a Sparse Probabilistic Kernel Binary Classifier

Algorithms / Computational Biology / Drug Discovery / Enzyme Inhibitors / THEORETICAL AND COMPUTATIONAL CHEMISTRY

4-Hydroxynonenal-Induced MEL Cell Differentiation Involves PKC Activity Translocation

Enzyme Inhibitors / Cell Division / Cell Differentiation / Mice / Animals / Biochemical / Hemoglobins / Maleimides / Biochemistry and cell biology / Biochemical / Hemoglobins / Maleimides / Biochemistry and cell biology

Nitric oxide depresses GABAA receptor function via coactivation of cGMP-dependent kinase and phosphodiesterase

Enzyme Inhibitors / Nitric oxide / Animals / Retina / Phosphodiesterase Inhibitors / Rats / Penicillamine / Protein Kinase / Guanylate Cyclase / cyclic GMP / Rats / Penicillamine / Protein Kinase / Guanylate Cyclase / cyclic GMP
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