Enzyme Inhibitors - Page 3

Dynasore, a Dynamin Inhibitor, Inhibits Trypanosoma cruzi Entry into Peritoneal Macrophages

Engineering / Physics / Chemistry / Electron Microscopy / Biology / Scanning Electron Microscopy / Enzyme Inhibitors / Medicine / Multidisciplinary / Cell line / Endocytosis / Animals / PLoS one / Hydrazones / Trypanosoma Cruzi / Phagocytosis / Indexation / Plasma Membrane / Scanning Electron Microscopy / Enzyme Inhibitors / Medicine / Multidisciplinary / Cell line / Endocytosis / Animals / PLoS one / Hydrazones / Trypanosoma Cruzi / Phagocytosis / Indexation / Plasma Membrane

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Leptin induces, via ERK1/ERK2 signal, functional activation of estrogen receptor alpha in MCF-7 cells

RNA / Immunohistochemistry / Enzyme Inhibitors / Biological Chemistry / Flavonoids / Signal Transduction / Biological Sciences / Adipose tissue / Humans / Biological / Leptin / Mitogen Activated Protein Kinase / CHEMICAL SCIENCES / Cell nucleus / HeLa cells / Disease Progression / Transfection / Ligands / Down-Regulation / Estrogen receptor alpha / Signal Transduction / Biological Sciences / Adipose tissue / Humans / Biological / Leptin / Mitogen Activated Protein Kinase / CHEMICAL SCIENCES / Cell nucleus / HeLa cells / Disease Progression / Transfection / Ligands / Down-Regulation / Estrogen receptor alpha

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Dynasore, a Dynamin Inhibitor, Inhibits Trypanosoma cruzi Entry into Peritoneal Macrophages

Engineering / Physics / Chemistry / Electron Microscopy / Biology / Scanning Electron Microscopy / Enzyme Inhibitors / Medicine / Multidisciplinary / Cell line / Endocytosis / Animals / PLoS one / Hydrazones / Trypanosoma Cruzi / Phagocytosis / Indexation / Plasma Membrane / Scanning Electron Microscopy / Enzyme Inhibitors / Medicine / Multidisciplinary / Cell line / Endocytosis / Animals / PLoS one / Hydrazones / Trypanosoma Cruzi / Phagocytosis / Indexation / Plasma Membrane

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HDAC Inhibitors Correct Frataxin Deficiency in a Friedreich Ataxia Mouse Model

Enzyme Inhibitors / Gene expression / Multidisciplinary / Cerebellum / Mice / Animals / Histone Modification / PLoS one / Chromatin / Introns / Histones / Mouse Model / Microarray Analysis / Myocardium / Chromatin Immunoprecipitation / Western blot / Acetylation / Neurodegenerative Disease / Histone deacetylase inhibitor / Nervous System / Autosomal Recessive / Acute Toxicity / Cardiac Disease / Friedreich Ataxia / Gene expression profiling / Histone deacetylase inhibitors / Iron binding proteins / Animals / Histone Modification / PLoS one / Chromatin / Introns / Histones / Mouse Model / Microarray Analysis / Myocardium / Chromatin Immunoprecipitation / Western blot / Acetylation / Neurodegenerative Disease / Histone deacetylase inhibitor / Nervous System / Autosomal Recessive / Acute Toxicity / Cardiac Disease / Friedreich Ataxia / Gene expression profiling / Histone deacetylase inhibitors / Iron binding proteins

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Vascular endothelial growth factor production in polymyalgia rheumatica

Immunology / Calcium / Immunohistochemistry / Enzyme Inhibitors / Vascular biology / Hepatology / Biological Sciences / Cell line / Thrombin / Pregnancy / Humans / Glioma / Female / Animals / Calcium Signaling / Arthritis / Lung / Mitogen Activated Protein Kinase / Integrins / Clinical Sciences / Human reproduction / Rats / Adult / Public health systems and services research / Western blot / Transforming Growth Factor Beta / Protein isoforms / Human Fibroblasts / MAP Kinase / Recombinant Proteins / Polymyalgia Rheumatica / Tissue Factor / Gangliosides / Factor Xa / Vascular Endothelial Growth Factor / Biology Reproduction / Intracellular Calcium / Isomerism / Hepatology / Biological Sciences / Cell line / Thrombin / Pregnancy / Humans / Glioma / Female / Animals / Calcium Signaling / Arthritis / Lung / Mitogen Activated Protein Kinase / Integrins / Clinical Sciences / Human reproduction / Rats / Adult / Public health systems and services research / Western blot / Transforming Growth Factor Beta / Protein isoforms / Human Fibroblasts / MAP Kinase / Recombinant Proteins / Polymyalgia Rheumatica / Tissue Factor / Gangliosides / Factor Xa / Vascular Endothelial Growth Factor / Biology Reproduction / Intracellular Calcium / Isomerism

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Src Kinase Inhibition Improves Acute Outcomes After Experimental Intracerebral Hemorrhage

Behavior / Treatment Outcome / Enzyme Inhibitors / Apoptosis / Stroke / Glucose Metabolism / Animals / Male / Cell Death / Kinase inhibitor / Clinical Sciences / Apoptose / Src kinase / Rats / Blood Flow / Intracerebral Hemorrhage / Pyrazoles / Cerebral Hemorrhage / Neurosciences / Direct Injection / Matrix Metalloproteinase / Glucose Metabolism / Animals / Male / Cell Death / Kinase inhibitor / Clinical Sciences / Apoptose / Src kinase / Rats / Blood Flow / Intracerebral Hemorrhage / Pyrazoles / Cerebral Hemorrhage / Neurosciences / Direct Injection / Matrix Metalloproteinase

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Sugar amino acid based peptide epoxyketones as potential proteasome inhibitors

Organic Chemistry / Enzyme Inhibitors / Bioorganic Chemistry / Cell line / Humans / Proteasome / Amino Acids / Active site / Amino Acid Profile / Bioorganic / PROTEASOME INHIBITOR / Proteasome / Amino Acids / Active site / Amino Acid Profile / Bioorganic / PROTEASOME INHIBITOR

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Muscarinic acetylcholine receptor activation induces Ca2+ mobilization and Na+/K+-ATPase activity inhibition in eel enterocytes

Endocrinology / Cognitive Science / Long Term Potentiation / Calcium / Enzyme Inhibitors / Multidisciplinary / Animal Production / Cytoskeleton / Patch-clamp and imaging techniques / Western blotting / Signal Transduction / Cannabinoids / Hippocampus / Tacrolimus / Humans / Cerebellum / Permeability / Mice / Animals / Metabotropic Glutamate Receptors / Calcium channels / Intestinal barrier function / Male / EELS / Calcium Signaling / Phosphorylation / Neurons / Single Cell / Clinical Sciences / Rats / Glutamine / Sodium / Analysis of Variance / SYNAPSES / Epithelial Attachment / Cellular and Molecular Neuroscience / Purkinje Cells / Veterinary Sciences / Action potential / Primary Culture / Calcineurin inhibitors / Nifedipine / Sirolimus / Second Messengers / Neurosciences / Plasma Membrane / Endosomes / Intracellular Calcium / Enterocytes / Calcium Channel Blockers / Phospholipase C / Multidisciplinary / Animal Production / Cytoskeleton / Patch-clamp and imaging techniques / Western blotting / Signal Transduction / Cannabinoids / Hippocampus / Tacrolimus / Humans / Cerebellum / Permeability / Mice / Animals / Metabotropic Glutamate Receptors / Calcium channels / Intestinal barrier function / Male / EELS / Calcium Signaling / Phosphorylation / Neurons / Single Cell / Clinical Sciences / Rats / Glutamine / Sodium / Analysis of Variance / SYNAPSES / Epithelial Attachment / Cellular and Molecular Neuroscience / Purkinje Cells / Veterinary Sciences / Action potential / Primary Culture / Calcineurin inhibitors / Nifedipine / Sirolimus / Second Messengers / Neurosciences / Plasma Membrane / Endosomes / Intracellular Calcium / Enterocytes / Calcium Channel Blockers / Phospholipase C

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Delivery of antimicrobials into parasites

Enzyme Inhibitors / Toxoplasma / Multidisciplinary / Toxoplasmosis / Toxoplasma gondii / Mice / Female / Animals / Oxidoreductases / Drug Delivery Systems / Enzyme / TRICLOSAN / Model System / Amino Acid Profile / Amino Acid Sequence / Recombinant Proteins / Enzymatic Activity / Mice / Female / Animals / Oxidoreductases / Drug Delivery Systems / Enzyme / TRICLOSAN / Model System / Amino Acid Profile / Amino Acid Sequence / Recombinant Proteins / Enzymatic Activity

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Unusual location and characterization of Cu/Zn-containing superoxide dismutase from filamentous fungus Humicola lutea

Microbiology / Medical Microbiology / Archives / Enzyme Inhibitors / Mitochondria / Western blotting / Cell Fractionation / Superoxide Dismutase / Enzyme / Glycosylation / Protein Sequence Analysis / Model System / Filamentous fungi / Enzyme activity / Molecular Mass / Molecular weight / Amino Acid Sequence / Ascomycota / Superoxide Anion / Electrophoretic Mobility / Western blotting / Cell Fractionation / Superoxide Dismutase / Enzyme / Glycosylation / Protein Sequence Analysis / Model System / Filamentous fungi / Enzyme activity / Molecular Mass / Molecular weight / Amino Acid Sequence / Ascomycota / Superoxide Anion / Electrophoretic Mobility

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Evidence for mitochondrial-derived alternative oxidase in the apicomplexan parasite Cryptosporidium parvum: a potential anti-microbial agent target

Microbiology / Zoology / Enzyme Inhibitors / Toxoplasma / Mitochondria / Toxoplasma gondii / Protein Targeting / Phylogeny / Sequence alignment / Animals / Oxidoreductases / Phylogenetic analysis / Genome / Plasmodium falciparum / For / Amino Acid Profile / Veterinary Sciences / Anti microbial / Amino Acid Sequence / PLANT PROTEINS / Gene Transfer / Alternative Oxidase / Mitochondrial Proteins / Toxoplasma gondii / Protein Targeting / Phylogeny / Sequence alignment / Animals / Oxidoreductases / Phylogenetic analysis / Genome / Plasmodium falciparum / For / Amino Acid Profile / Veterinary Sciences / Anti microbial / Amino Acid Sequence / PLANT PROTEINS / Gene Transfer / Alternative Oxidase / Mitochondrial Proteins

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Hypoxia sustains glioblastoma radioresistance through ERKs/DNA-PKcs/HIF-1α functional interplay

Oncology / Enzyme Inhibitors / Humans / Nitriles / Glioblastoma / Oxygen / Radiation Tolerance / Benzamides / Oxygen / Radiation Tolerance / Benzamides

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PDGF signal transduction inhibition ameliorates experimental mesangial proliferative glomerulonephritis1

Enzyme Inhibitors / Extracellular Matrix / Cell Division / Signal Transduction / Cell line / Smooth muscle / Kidney / Collagen / Animals / Male / Fibroblast Growth Factor / Clinical Sciences / Rats / Wistar Rats / Cell Proliferation / Growth Factor / Renal disease / Benzamides / Receptor Tyrosine Kinase / Smooth muscle / Kidney / Collagen / Animals / Male / Fibroblast Growth Factor / Clinical Sciences / Rats / Wistar Rats / Cell Proliferation / Growth Factor / Renal disease / Benzamides / Receptor Tyrosine Kinase

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Protein Kinase A Activation Promotes Plasma Membrane Insertion of DCC from an Intracellular Pool: A Novel Mechanism Regulating Commissural Axon Extension

Neuroscience / Enzyme Inhibitors / Molecular Mechanics / cyclic AMP / Animals / Spinal Cord / P-glycoprotein / Axon Guidance / The / Rats / Exocytosis / Cell Surface Markers / Axons / Plasma Membrane / Protein Transport / Cell Adhesion Molecules / Axon Outgrowth / Spinal Cord / P-glycoprotein / Axon Guidance / The / Rats / Exocytosis / Cell Surface Markers / Axons / Plasma Membrane / Protein Transport / Cell Adhesion Molecules / Axon Outgrowth

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Protein kinase A activation promotes plasma membrane insertion of DCC from an intracellular pool: A novel mechanism regulating commissural axon extension

Neuroscience / Enzyme Inhibitors / Molecular Mechanics / cyclic AMP / Animals / Spinal Cord / P-glycoprotein / Axon Guidance / The / Rats / Exocytosis / Cell Surface Markers / Axons / Plasma Membrane / Protein Transport / Cell Adhesion Molecules / Axon Outgrowth / Spinal Cord / P-glycoprotein / Axon Guidance / The / Rats / Exocytosis / Cell Surface Markers / Axons / Plasma Membrane / Protein Transport / Cell Adhesion Molecules / Axon Outgrowth

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Adenine Phosphoribosyltransferase Deficiency

Kidney diseases / Enzyme Inhibitors / Adolescent / Humans / Child / Female / Animals / Inborn errors of metabolism / Male / Young Adult / Infant / Pediatric Nephrology / Pediatric / Phenotype / Recurrence / Clinical Sciences / Urolithiasis / Retrospective Studies / Prognosis / Biological markers / Disease Progression / Adenine / Allopurinol / Predictive value of tests / Female / Animals / Inborn errors of metabolism / Male / Young Adult / Infant / Pediatric Nephrology / Pediatric / Phenotype / Recurrence / Clinical Sciences / Urolithiasis / Retrospective Studies / Prognosis / Biological markers / Disease Progression / Adenine / Allopurinol / Predictive value of tests

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