Structure activity Relationship - Page 5

Quinuclidine Derivatives as Potential Antiparasitics

Microbiology / Medical Microbiology / Animals / Enzyme / Rats / Trypanosoma Cruzi / Trypanosoma brucei / Trypanosoma brucei brucei / Plasmodium falciparum / Antimicrobial agents / Sterols / Structure activity Relationship / Recombinant Proteins / Drug Targeting / Leishmania Major / Plasma Membrane / Area of Interest / Molecular Structure / Trypanosoma Cruzi / Trypanosoma brucei / Trypanosoma brucei brucei / Plasmodium falciparum / Antimicrobial agents / Sterols / Structure activity Relationship / Recombinant Proteins / Drug Targeting / Leishmania Major / Plasma Membrane / Area of Interest / Molecular Structure

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Identification of 2-nonynoic acid, a cosmetic component, as a potential trigger of primary biliary cirrhosis

Immunology / Autoimmunity / Humans / Female / Male / Quantitative Structure Activity Relationship / Cosmetics / Molecular Mimicry / Occupational Exposure / Indexation / Structure activity Relationship / Primary Biliary Cirrhosis / Methyl Ester / Chemical Structure / Autoantibodies / Quantitative Structure Activity Relationship / Cosmetics / Molecular Mimicry / Occupational Exposure / Indexation / Structure activity Relationship / Primary Biliary Cirrhosis / Methyl Ester / Chemical Structure / Autoantibodies

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Structural and functional characterisation of an influenza virus RNA polymerase-genomic RNA complex

Microbiology / Zoology / Immunology / Molecular Biology / Structural Biology / Biomaterials / Tissue Engineering / Medical Microbiology / Virology / Wastewater Treatment / Hydrogels / Transcription Factors / Multidisciplinary / Extracellular Matrix / Animal Production / Molecular Mechanics / Enzyme Kinetics / Immunogenetics / Catalytic Mechanism / Biological Sciences / Protein Structure and Function / Crystal structure / Molecular Immunology / Heparin / Sequence alignment / Basement Membrane / Biological Wastewater Treatment / Mice / Animals / Blood / Polymerase Chain Reaction / Physical sciences / Special functions / Detoxification / Fisheries Sciences / Fibroblast Growth Factor / Glycosaminoglycan / Transcription Factor / Enzyme / Clinical Sciences / Active site / Polyvinyl alcohol / Poly Vinyl Alcohol / Amino Acid Profile / Veterinary Sciences / Biological activity / Amino Acid Sequence / Base Sequence / Materials Testing / Growth Factor / Structure activity Relationship / Protein Binding / D structure / Biocompatible Materials / Cell Surface Markers / Cardiovascular Magnetic Resonance / Site-directed Mutagenesis / Binding Site / Biochemistry and cell biology / Biomechanical Phenomena / Biomaterials / Tissue Engineering / Medical Microbiology / Virology / Wastewater Treatment / Hydrogels / Transcription Factors / Multidisciplinary / Extracellular Matrix / Animal Production / Molecular Mechanics / Enzyme Kinetics / Immunogenetics / Catalytic Mechanism / Biological Sciences / Protein Structure and Function / Crystal structure / Molecular Immunology / Heparin / Sequence alignment / Basement Membrane / Biological Wastewater Treatment / Mice / Animals / Blood / Polymerase Chain Reaction / Physical sciences / Special functions / Detoxification / Fisheries Sciences / Fibroblast Growth Factor / Glycosaminoglycan / Transcription Factor / Enzyme / Clinical Sciences / Active site / Polyvinyl alcohol / Poly Vinyl Alcohol / Amino Acid Profile / Veterinary Sciences / Biological activity / Amino Acid Sequence / Base Sequence / Materials Testing / Growth Factor / Structure activity Relationship / Protein Binding / D structure / Biocompatible Materials / Cell Surface Markers / Cardiovascular Magnetic Resonance / Site-directed Mutagenesis / Binding Site / Biochemistry and cell biology / Biomechanical Phenomena

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N-Aryl-gamma-lactams as integrin alphavbeta3 antagonists

Organic Chemistry / Humans / Animals / Molecular Conformation / Bioorganic and medicinal Chemistry / Structure activity Relationship / Ligands / Structure activity Relationship / Ligands

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Antioxidant activity and phenolic composition of sumac (Rhus coriaria L.) extracts

Engineering / Analytical Chemistry / Organic Chemistry / Nutrition and Dietetics / Plant Biology / Medicinal Plants / Food Chemistry / Flavonoids / Multidisciplinary / Free Radical / Functional Foods / Antioxidants / Black Tea / Gallic acid / High Pressure Liquid Chromatography / CHEMICAL SCIENCES / Antioxidant Activity / Liquid Chromatography / Electrospray Ionization Mass Spectrometry / Phenols / Ethyl Acetate / Phenolic compound / Mediterranean region / Lavandula / Food Sciences / Agricultural and Food Chemistry / Corylus / Structure activity Relationship / Organic and Conventional Agriculture / Total Phenolics / Chlorogenic Acid / Superoxides / Palabras Clave: BIM / Plant Leaves / Medicinal Plants / Food Chemistry / Flavonoids / Multidisciplinary / Free Radical / Functional Foods / Antioxidants / Black Tea / Gallic acid / High Pressure Liquid Chromatography / CHEMICAL SCIENCES / Antioxidant Activity / Liquid Chromatography / Electrospray Ionization Mass Spectrometry / Phenols / Ethyl Acetate / Phenolic compound / Mediterranean region / Lavandula / Food Sciences / Agricultural and Food Chemistry / Corylus / Structure activity Relationship / Organic and Conventional Agriculture / Total Phenolics / Chlorogenic Acid / Superoxides / Palabras Clave: BIM / Plant Leaves

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New clerodane diterpenoids from Laetia procera (Poepp.) Eichler (Flacourtiaceae), with antiplasmodial and antileishmanial activities

Organic Chemistry / Leishmania / Magnetic Resonance Spectroscopy / Humans / Animals / Selection Index / Magnolia / Diterpenes / Plasmodium falciparum / Antimalarials / Bioorganic and medicinal Chemistry / Structure activity Relationship / Molecular Structure / Selection Index / Magnolia / Diterpenes / Plasmodium falciparum / Antimalarials / Bioorganic and medicinal Chemistry / Structure activity Relationship / Molecular Structure

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Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs

Organic Chemistry / Fungi / Molecular modeling / Bacteria / Antifungal Activity / Structure Elucidation / Anti-Bacterial Agents / Antifungal Agents / Microbial Sensitivity Tests / Bioorganic and medicinal Chemistry / Thiazoles / Structure activity Relationship / Isomerism / Structure Elucidation / Anti-Bacterial Agents / Antifungal Agents / Microbial Sensitivity Tests / Bioorganic and medicinal Chemistry / Thiazoles / Structure activity Relationship / Isomerism

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Vanadium polypyridyl compounds as potential antiparasitic and antitumoral agents: New achievements

Inorganic Chemistry / Leishmania / Inorganic / Apoptosis / DNA / Humans / Chagas disease / Vanadium / Trypanosoma Cruzi / Trypanocidal Agents / Inorganic Biochemistry / Structure activity Relationship / Cell Survival / Antineoplastic Agents / Humans / Chagas disease / Vanadium / Trypanosoma Cruzi / Trypanocidal Agents / Inorganic Biochemistry / Structure activity Relationship / Cell Survival / Antineoplastic Agents

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Novel sulfonylurea derivatives as H3 receptor antagonists. Preliminary SAR studies

Organic Chemistry / SEM / Humans / Structure activity Relationship

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Antiplasmodial and Leishmanicidal Activities of 2-Cyano-3-(4-phenylpiperazine-1-carboxamido) Quinoxaline 1,4-Dioxide Derivatives

Organic Chemistry / Catalysis / Cercopithecus aethiops / Animals / Molecules / Plasmodium falciparum / Leishmania infantum / Structure activity Relationship / Vero cells / Solvents / Plasmodium falciparum / Leishmania infantum / Structure activity Relationship / Vero cells / Solvents

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Preparation and Pharmacological Characterization of trans -2-Amino-5(6)-fluoro-6(5)-hydroxy-1-phenyl-2,3-dihydro-1 H -indenes as D 2 -like Dopamine Receptor Agonists

Organic Chemistry / Medicinal Chemistry / cyclic AMP / Animals / dopamine receptor D4 / Rats / Swine / Radioligand Assay / Medicinal / Structure activity Relationship / cyclic GMP / Rats / Swine / Radioligand Assay / Medicinal / Structure activity Relationship / cyclic GMP

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S-Euglobals: Biomimetic synthesis, antileishmanial, antimalarial, and antimicrobial activities

Organic Chemistry / Magnetic Resonance Spectroscopy / Cell line / Animals / Antimicrobial activity / Staphylococcus aureus / Terpenes / Antibacterial activity / Anti-Bacterial Agents / Cytotoxic Activity / Biomimetic materials / Plasmodium falciparum / Bioorganic and medicinal Chemistry / Structure activity Relationship / Phloroglucinol / Methicillin Resistant Staphylococcus Aureus / Molecular Structure / Staphylococcus aureus / Terpenes / Antibacterial activity / Anti-Bacterial Agents / Cytotoxic Activity / Biomimetic materials / Plasmodium falciparum / Bioorganic and medicinal Chemistry / Structure activity Relationship / Phloroglucinol / Methicillin Resistant Staphylococcus Aureus / Molecular Structure

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2-(2,4-dihydroxyphenyl)-5-(E)-propenylbenzofuran promotes endothelial nitric oxide synthase activity in human endothelial cells

Calcium / Signal Transduction / Humans / Nitric oxide / Lignans / Phosphorylation / BIOCHEMICAL PHARMACOLOGY / Structure activity Relationship / Chelating Agents / Furans / Intracellular Space / Phosphorylation / BIOCHEMICAL PHARMACOLOGY / Structure activity Relationship / Chelating Agents / Furans / Intracellular Space

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Non-Peptide αvβ3 antagonists. Part 3: Identification of potent RGD mimetics incorporating novel β-Amino acids as aspartic acid replacements

Organic Chemistry / Dogs / Osteoporosis / Humans / Animals / D-Aspartic Acid / Amino Acids / Molecular Mimicry / Amino Acid Profile / Bioorganic and medicinal Chemistry / Structure activity Relationship / Protein Binding / Physicochemical Properties / D-Aspartic Acid / Amino Acids / Molecular Mimicry / Amino Acid Profile / Bioorganic and medicinal Chemistry / Structure activity Relationship / Protein Binding / Physicochemical Properties

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Acyl sulfonamide anti-proliferatives. Part 2: Activity of heterocyclic sulfonamide derivatives

Organic Chemistry / Humans / Bioorganic and medicinal Chemistry / Cell Proliferation / Structure activity Relationship / Vascular Endothelial Growth Factor

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Anti-tumor agents 255: Novel glycyrrhetinic acid–dehydrozingerone conjugates as cytotoxic agents

Organic Chemistry / Drug Discovery / Humans / Ursolic Acid / Cytotoxic Activity / Neoplasms / Bioorganic and medicinal Chemistry / Structure activity Relationship / Antineoplastic Agents / Cytotoxins / Molecular Structure / Neoplasms / Bioorganic and medicinal Chemistry / Structure activity Relationship / Antineoplastic Agents / Cytotoxins / Molecular Structure

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