Antimalarials - Page 10

Efficacy and effectiveness of dihydroartemisinin-piperaquine versus artesunate-mefloquine in falciparum malaria: an open-label randomised comparison

Survival Analysis / Treatment Outcome / Adolescent / Myanmar / Humans / Child / Multidrug Resistance / Female / Animals / Male / Infant / Randomised Controlled Trial / Recurrence / Sesquiterpenes / Lancet / Kaplan-Meier / Plasmodium falciparum / Antimalarials / Combination drug therapy / Quinolines / Context of Use / Age Groups / Mefloquine / Relative Risk / Child / Multidrug Resistance / Female / Animals / Male / Infant / Randomised Controlled Trial / Recurrence / Sesquiterpenes / Lancet / Kaplan-Meier / Plasmodium falciparum / Antimalarials / Combination drug therapy / Quinolines / Context of Use / Age Groups / Mefloquine / Relative Risk

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Effi cacy and eff ectiveness of dihydroartemisinin-piperaquine versus artesunate-mefl oquine in falciparum malaria: an open-label randomised comparison

Survival Analysis / Treatment Outcome / Adolescent / Myanmar / Humans / Child / Multidrug Resistance / Female / Animals / Male / Infant / Randomised Controlled Trial / Recurrence / Sesquiterpenes / Lancet / Kaplan-Meier / Plasmodium falciparum / Antimalarials / Combination drug therapy / Quinolines / Context of Use / Age Groups / Mefloquine / Relative Risk / Child / Multidrug Resistance / Female / Animals / Male / Infant / Randomised Controlled Trial / Recurrence / Sesquiterpenes / Lancet / Kaplan-Meier / Plasmodium falciparum / Antimalarials / Combination drug therapy / Quinolines / Context of Use / Age Groups / Mefloquine / Relative Risk

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Biological activities of extracts from endophytic fungi isolated from Garcinia plants

Immunology / Medical Microbiology / Fungi / Antioxidants / Cercopithecus aethiops / Cell line / Humans / Animals / Endophytic Fungi / Antimalarials / Biological activity / Antineoplastic Agents / Antiviral Agents / Cell line / Humans / Animals / Endophytic Fungi / Antimalarials / Biological activity / Antineoplastic Agents / Antiviral Agents

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4- N -, 4- S -, and 4- O -Chloroquine Analogues: Influence of Side Chain Length and Quinolyl Nitrogen p K a on Activity vs Chloroquine Resistant Malaria

Organic Chemistry / Medicinal Chemistry / Fluorescent Dyes and Reagents / Animals / Drug Resistance / Nitrogen / Medicinal / Plasmodium falciparum / Antimalarials / Chloroquine / Structure activity Relationship / Organic Chemicals / "Intercalating Agents" / Nitrogen / Medicinal / Plasmodium falciparum / Antimalarials / Chloroquine / Structure activity Relationship / Organic Chemicals / "Intercalating Agents"

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Identification of a nucleoside/nucleobase transporter from Plasmodium falciparum, a novel target for anti-malarial chemotherapy

Kinetics / Biological Sciences / Phylogeny / Xenopus / Animals / Biochemical / CHEMICAL SCIENCES / Molecular cloning / Protein Secondary Structure Prediction / Time Factors / Substrate Specificity / Plasmodium falciparum / Antimalarials / Protozoan Proteins / Amino Acid Sequence / Nucleosides / Cations / Hydrogen-Ion Concentration / Adenine / Biochemical / CHEMICAL SCIENCES / Molecular cloning / Protein Secondary Structure Prediction / Time Factors / Substrate Specificity / Plasmodium falciparum / Antimalarials / Protozoan Proteins / Amino Acid Sequence / Nucleosides / Cations / Hydrogen-Ion Concentration / Adenine

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Preliminary pharmaceutical development of antimalarial–antibiotic cotherapy as a pre-referral paediatric treatment of fever in malaria endemic areas

Malaria / Pharmaceutical Technology / Powder Diffraction / Crystallization / Pharmaceutical Chemistry / Macromolecular X-Ray Crystallography / Pharmaceutics / Humans / Animals / Endemic Diseases / Solubility / Anti-Bacterial Agents / Antimalarials / Tablets / Age Factors / Rabbits / Azithromycin / Capsules / Excipients / Biological Availability / Macromolecular X-Ray Crystallography / Pharmaceutics / Humans / Animals / Endemic Diseases / Solubility / Anti-Bacterial Agents / Antimalarials / Tablets / Age Factors / Rabbits / Azithromycin / Capsules / Excipients / Biological Availability

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G6PD deficiency in Latin America: systematic review on prevalence and variants

Medical Microbiology / Latin America / Humans / Female / Male / Caribbean region / Prevalence / Antimalarials / Primaquine / Hemolysis / Caribbean region / Prevalence / Antimalarials / Primaquine / Hemolysis

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Spatial distribution of G6PD deficiency variants across malaria-endemic regions

Spatial Analysis / Global Health / Medical Microbiology / Malaria / Risk assessment / Humans / Antimalarials / Genetic variation / Risk Assessment / Primaquine / Humans / Antimalarials / Genetic variation / Risk Assessment / Primaquine

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Spatial distribution of G6PD deficiency variants across malaria-endemic regions - Supplementary Information 4

Spatial Analysis / Global Health / Medical Microbiology / Malaria / Risk assessment / Humans / Antimalarials / Genetic variation / Risk Assessment / Primaquine / Humans / Antimalarials / Genetic variation / Risk Assessment / Primaquine

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Spatial distribution of G6PD deficiency variants across malaria-endemic regions - Supplementary Information 1-2

Spatial Analysis / Global Health / Medical Microbiology / Malaria / Risk assessment / Humans / Antimalarials / Genetic variation / Risk Assessment / Primaquine / Humans / Antimalarials / Genetic variation / Risk Assessment / Primaquine

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New Antimalarial Hits from Dacryodes edulis (Burseraceae) - Part I: Isolation, In Vitro Activity, In Silico â€œdrug-likenessâ€� and Pharmacokinetic Profiles

Drug interactions / Multidisciplinary / Cell line / Animals / PLoS one / Plant extracts / Epithelial cells / Plasmodium falciparum / Antimalarials / Toxicity Tests / Quinine / Plant extracts / Epithelial cells / Plasmodium falciparum / Antimalarials / Toxicity Tests / Quinine

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A Specific Inhibitor of PfCDPK4 Blocks Malaria Transmission: Chemical-genetic Validation

Enzyme Inhibitors / Infectious Diseases / Biological Sciences / Protein Kinases / Mice / Animals / Flagella / Plasmodium falciparum / Antimalarials / Protozoan Proteins / Animals / Flagella / Plasmodium falciparum / Antimalarials / Protozoan Proteins

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Intervals to Plasmodium falciparum recurrence after anti-malarial treatment in pregnancy: a longitudinal prospective cohort

Medical Microbiology / Malaria / Thailand / Adolescent / Prospective studies / Pregnancy / Humans / Female / Polymerase Chain Reaction / Young Adult / Recurrence / Longitudinal Studies / Genotype / Adult / Time Factors / Plasmodium falciparum / Antimalarials / Protozoan Proteins / Pregnancy / Humans / Female / Polymerase Chain Reaction / Young Adult / Recurrence / Longitudinal Studies / Genotype / Adult / Time Factors / Plasmodium falciparum / Antimalarials / Protozoan Proteins

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Hydroperoxide and Endoperoxide Lactones from Photooxygenation of 3-Alkylidenedihydrofuran-2,4-diones

Inorganic Chemistry / Organic Chemistry / Photochemistry / Hydrogen Peroxide / Antimalarials / Alkenes / Oxidation-Reduction / Furans / Lactones / Butyrolactone / Alkenes / Oxidation-Reduction / Furans / Lactones / Butyrolactone

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In vitro antileishmanial, antiplasmodial and cytotoxic activities of phenolics and triterpenoids from Baccharis dracunculifolia D. C. (Asteraceae)

Complementary and Alternative Medicine / Plant Biology / Cytotoxicity / Propolis / Cercopithecus aethiops / Animals / Ursolic Acid / Phenols / Plant extracts / Cytotoxic Activity / Plasmodium falciparum / Antimalarials / Fitoterapia / Microbial Sensitivity Tests / Phytochemicals / Trypanocidal Agents / Vero cells / Triterpenoids / Baccharis / Triterpenes / Plant Leaves / Animals / Ursolic Acid / Phenols / Plant extracts / Cytotoxic Activity / Plasmodium falciparum / Antimalarials / Fitoterapia / Microbial Sensitivity Tests / Phytochemicals / Trypanocidal Agents / Vero cells / Triterpenoids / Baccharis / Triterpenes / Plant Leaves

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Helicases − feasible antimalarial drug target for Plasmodium falciparum

Humans / Animals / Plasmodium falciparum / Antimalarials / Biochemistry and cell biology

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