Antimalarials

Antiplasmodial Alkaloids from Desmos rostrata

Natural Products / Medicinal Plants / Vietnam / Biological Sciences / Humans / Animals / Alkaloids / CHEMICAL SCIENCES / Plasmodium falciparum / Antimalarials / Natural / KB cells / Molecular Structure / Animals / Alkaloids / CHEMICAL SCIENCES / Plasmodium falciparum / Antimalarials / Natural / KB cells / Molecular Structure

Mefloquine pharmacokinetics and mefloquine-artesunate effectiveness in Peruvian patients with uncomplicated Plasmodium falciparum malaria

Medical Microbiology / Malaria / Peru / Treatment Outcome / Adolescent / Humans / Female / Animals / Blood sampling / Male / Young Adult / High Performance Liquid Chromatography / High Pressure Liquid Chromatography / Middle Aged / Adult / Ethnic Group / Time Factors / Plasmodium falciparum / Antimalarials / Combination drug therapy / Mefloquine / Humans / Female / Animals / Blood sampling / Male / Young Adult / High Performance Liquid Chromatography / High Pressure Liquid Chromatography / Middle Aged / Adult / Ethnic Group / Time Factors / Plasmodium falciparum / Antimalarials / Combination drug therapy / Mefloquine

Potent Plasmodium falciparum Gametocytocidal Activity of Diaminonaphthoquinones, Lead Antimalarial Chemotypes Identified in an Antimalarial Compound Screen

Microbiology / Medical Microbiology / Humans / Naphthoquinones / Plasmodium falciparum / Antimalarials / Imidazoles / Structure activity Relationship / Antimalarials / Imidazoles / Structure activity Relationship

An Endoperoxide-Based Hybrid Approach to Deliver Falcipain Inhibitors Inside Malaria Parasites

Organic Chemistry / Malaria / Humans / Drug Resistance / Plasmodium falciparum / Antimalarials / Cysteine endopeptidases / Chloroquine / Structure activity Relationship / Erythrocytes / Hemoglobins / Cysteine Proteinase Inhibitors / Antimalarials / Cysteine endopeptidases / Chloroquine / Structure activity Relationship / Erythrocytes / Hemoglobins / Cysteine Proteinase Inhibitors

Antimalarial Exposure Delays Plasmodium falciparum Intra-Erythrocytic Cycle and Drives Drug Transporter Genes Expression

Cell Cycle / Gene expression / Multidisciplinary / Drug Resistance / Membrane transport proteins / PLoS one / Plasmodium falciparum / Antimalarials / Combination drug therapy / Protozoan Proteins / Erythrocytes / Non linear regression / Mefloquine / Gene Expression Regulation / PLoS one / Plasmodium falciparum / Antimalarials / Combination drug therapy / Protozoan Proteins / Erythrocytes / Non linear regression / Mefloquine / Gene Expression Regulation

CYP2C8 polymorphism frequencies among malaria patients in Zanzibar

Polymorphism / Tanzania / Humans / Pharmacogenetics / Female / Male / Infant / European / Prevalence / Antimalarials / Amodiaquine / Male / Infant / European / Prevalence / Antimalarials / Amodiaquine

A comprehensive survey of polymorphisms conferring anti-malarial resistance in Plasmodium falciparum across Pakistan

Medical Microbiology / Pakistan / Malaria / Adolescent / Humans / Child / Female / Drug Resistance / Male / Polymerase Chain Reaction / Young Adult / Infant / Gene Dosage / Aged / Middle Aged / Genotype / Adult / Plasmodium falciparum / Antimalarials / Protozoan Proteins / Amino Acid Substitution Rates / Child / Female / Drug Resistance / Male / Polymerase Chain Reaction / Young Adult / Infant / Gene Dosage / Aged / Middle Aged / Genotype / Adult / Plasmodium falciparum / Antimalarials / Protozoan Proteins / Amino Acid Substitution Rates

CoMSIA and POM analyses of anti-malarial activity of synthetic prodiginines

Organic Chemistry / Quantitative Structure Activity Relationship / Prodigiosin / Antimalarials / Molecular Structure

2-Acylamino-5-chlorobenzophenones with enhanced selectivity towards malaria parasites

Organic Chemistry / Malaria / Humans / Animals / Benzophenones / HeLa cells / Plasmodium falciparum / Antimalarials / HeLa cells / Plasmodium falciparum / Antimalarials

2-(Arylpropionylamino)- and 2-(arylacryloylamino)benzophenones: farnesyltransferase inhibition and antimalarial activity

Mass Spectrometry / Magnetic Resonance Spectroscopy / Humans / Escherichia coli / Animals / Pharmazie / Benzophenones / Plasmodium falciparum / Antimalarials / Thiazoles / Structure activity Relationship / Pharmazie / Benzophenones / Plasmodium falciparum / Antimalarials / Thiazoles / Structure activity Relationship

Transient Lesion in the Splenium of the Corpus Callosum in Acute Uncomplicated Falciparum Malaria

Magnetic Resonance Imaging / Thailand / Prospective studies / Humans / Corpus Callosum / Male / Young Adult / Follow-up studies / Thrombocytopenia / Middle Aged / Adult / Antimalarials / Combination drug therapy / Chloroquine / Primaquine / Hemolysis / Male / Young Adult / Follow-up studies / Thrombocytopenia / Middle Aged / Adult / Antimalarials / Combination drug therapy / Chloroquine / Primaquine / Hemolysis

Applying malaria parasite’s heme detoxification system for screening potential antimalarial drugs

Analytical Chemistry / Malaria / Animals / Detoxification / Heme / Plasmodium falciparum / Antimalarials / Analytical Biochemistry / Biochemistry and cell biology / Plasmodium falciparum / Antimalarials / Analytical Biochemistry / Biochemistry and cell biology

Effect of Antimalarial Drugs on Plasmodium falciparum Gametocytes

Microbiology / Biological Sciences / Female / Animals / Male / Infectious / Plasmodium falciparum / Antimalarials / Infectious / Plasmodium falciparum / Antimalarials

Plasmodium falciparum neutral aminopeptidases: new targets for anti-malarials

Biological Sciences / Humans / CHEMICAL SCIENCES / Plasmodium falciparum / Antimalarials

Cardiac complication after experimental human malaria infection: a case report

Medical Microbiology / Malaria / Treatment Outcome / Case Report / Humans / Female / Animals / Vaccination / Human Experimentation / Experimental Infection / Acute Coronary Syndrome / Adult / Plasmodium falciparum / Antimalarials / Combination drug therapy / Chest Pain / Malaria Vaccines / Female / Animals / Vaccination / Human Experimentation / Experimental Infection / Acute Coronary Syndrome / Adult / Plasmodium falciparum / Antimalarials / Combination drug therapy / Chest Pain / Malaria Vaccines

Adaptive Copy Number Evolution in Malaria Parasites

Genetics / Geography / Polymorphism / Molecular Evolution / Thailand / LAOS / Humans / Animals / Drug Resistance / Polymerase Chain Reaction / Parallel Evolution / Gene Dosage / Enzyme / Positive Selection / Plasmodium falciparum / Antimalarials / Linkage Disequilibrium / PLoS Genetics / LAOS / Humans / Animals / Drug Resistance / Polymerase Chain Reaction / Parallel Evolution / Gene Dosage / Enzyme / Positive Selection / Plasmodium falciparum / Antimalarials / Linkage Disequilibrium / PLoS Genetics

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