Antimalarials

Antimalarial Activity of Sesquiterpene Lactones from Vernonia cinerea

Magnetic Resonance Spectroscopy / Animals / Drug Resistance / Sesquiterpenes / Plant extracts / Plasmodium falciparum / Antimalarials / Sensitivity and Specificity / Chloroquine / Structure activity Relationship / Lactones / Molecular Structure / Plasmodium falciparum / Antimalarials / Sensitivity and Specificity / Chloroquine / Structure activity Relationship / Lactones / Molecular Structure

Efficacy and effectiveness of dihydroartemisinin-piperaquine versus artesunate-mefloquine in falciparum malaria: an open-label randomised comparison

Survival Analysis / Treatment Outcome / Adolescent / Myanmar / Humans / Child / Multidrug Resistance / Female / Animals / Male / Infant / Randomised Controlled Trial / Recurrence / Sesquiterpenes / Lancet / Kaplan-Meier / Plasmodium falciparum / Antimalarials / Combination drug therapy / Quinolines / Context of Use / Age Groups / Mefloquine / Relative Risk / Child / Multidrug Resistance / Female / Animals / Male / Infant / Randomised Controlled Trial / Recurrence / Sesquiterpenes / Lancet / Kaplan-Meier / Plasmodium falciparum / Antimalarials / Combination drug therapy / Quinolines / Context of Use / Age Groups / Mefloquine / Relative Risk

In vivo antimalarial activities of ethanolic crude extracts and fractions of leaf and root of Carpolobia lutea

Water / Pakistan / Malaria / Survival / Mice / Female / Animals / Male / Ethanol / Plant Roots / Plant extracts / Antimalarials / Chloroquine / Plasmodium berghei / Solvents / Plant Leaves / Female / Animals / Male / Ethanol / Plant Roots / Plant extracts / Antimalarials / Chloroquine / Plasmodium berghei / Solvents / Plant Leaves

N -Aryl-2-aminobenzimidazoles: Novel, Efficacious, Antimalarial Lead Compounds

Pharmacology / Chemistry / Organic Chemistry / Pharmacy / Medicinal Chemistry / Malaria / Humans / Animals / Rats / Hepatocytes / Plasmodium falciparum / Antimalarials / Benzimidazoles / Structure activity Relationship / Plasmodium berghei / Malaria / Humans / Animals / Rats / Hepatocytes / Plasmodium falciparum / Antimalarials / Benzimidazoles / Structure activity Relationship / Plasmodium berghei

Antimalarial quinolones: Synthesis, potency, and mechanistic studies

Microbiology / Experimental parasitology / Humans / Multidrug Resistance / Animals / Drug Resistance / Quinolones / Experimental / Mode of action / Cytochrome B / Plasmodium falciparum / Antimalarials / Combination drug therapy / Veterinary Sciences / Erythrocytes / Oxygen Consumption / Drug Resistance / Quinolones / Experimental / Mode of action / Cytochrome B / Plasmodium falciparum / Antimalarials / Combination drug therapy / Veterinary Sciences / Erythrocytes / Oxygen Consumption

In Vitro and In Vivo Properties of Ellagic Acid in Malaria Treatment

Microbiology / Medical Microbiology / Plasmodium / Infectious Disease / Mice / Female / Animals / Antioxidant Activity / ATOVAQUONE / Plasmodium falciparum / Antimalarials / Antimicrobial agents / Combination drug therapy / Plant production / Molecular weight / Mechanism of action / Chloroquine / Active Ingredient / Erythrocytes / Effective Dose / Mefloquine / Molecular Structure / Female / Animals / Antioxidant Activity / ATOVAQUONE / Plasmodium falciparum / Antimalarials / Antimicrobial agents / Combination drug therapy / Plant production / Molecular weight / Mechanism of action / Chloroquine / Active Ingredient / Erythrocytes / Effective Dose / Mefloquine / Molecular Structure

In vitro antiplasmodial activity, cytotoxicity and chemical profiles of sponge species of Cuban coasts

Malaria / Porifera / STEROIDS / Multidisciplinary / Cuba / Humans / Mice / Animals / Natural Product / Alkaloids / HeLa cells / Plasmodium falciparum / Antimalarials / Antineoplastic Agents / Plasmodium berghei / Triterpenes / Oceans and Seas / Humans / Mice / Animals / Natural Product / Alkaloids / HeLa cells / Plasmodium falciparum / Antimalarials / Antineoplastic Agents / Plasmodium berghei / Triterpenes / Oceans and Seas

G6PD deficiency in Latin America: systematic review on prevalence and variants

Medical Microbiology / Latin America / Humans / Female / Male / Caribbean region / Prevalence / Antimalarials / Primaquine / Hemolysis / Caribbean region / Prevalence / Antimalarials / Primaquine / Hemolysis

Antiplasmodial activity of Aspidosperma indole alkaloids

Complementary and Alternative Medicine / Plant Biology / Phytomedicine / Cell line / Humans / Animals / Drug Resistance / Alkaloids / Plant extracts / Plasmodium falciparum / Antimalarials / Toxicity Tests / Quinolines / Chloroquine / Structure activity Relationship / Indole Alkaloids / Molecular Structure / Animals / Drug Resistance / Alkaloids / Plant extracts / Plasmodium falciparum / Antimalarials / Toxicity Tests / Quinolines / Chloroquine / Structure activity Relationship / Indole Alkaloids / Molecular Structure

Potent Plasmodium falciparum Gametocytocidal Activity of Diaminonaphthoquinones, Lead Antimalarial Chemotypes Identified in an Antimalarial Compound Screen

Microbiology / Medical Microbiology / Humans / Naphthoquinones / Plasmodium falciparum / Antimalarials / Imidazoles / Structure activity Relationship / Antimalarials / Imidazoles / Structure activity Relationship

Antiprotozoal quinones. IV. 2-Amino-1,4-naphthoquinone imines as potential antimalarials

Organic Chemistry / Medicinal Chemistry / Malaria / Mice / Animals / Antimalarials

Comparative Ex Vivo Activity of Novel Endoperoxides in Multidrug-Resistant Plasmodium falciparum and P. vivax

Microbiology / Medical Microbiology / Plasmodium falciparum / Antimalarials / Microbial Sensitivity Tests / Quinolines / Chloroquine / Adamantane / Amodiaquine / Plasmodium Vivax / Quinolines / Chloroquine / Adamantane / Amodiaquine / Plasmodium Vivax

In vivo efficacy of artemether-lumefantrine against uncomplicated Plasmodium falciparum malaria in Central Ethiopia

Medical Microbiology / Malaria / Survival Analysis / Treatment Outcome / Ethiopia / Adolescent / Humans / Child / Female / Male / Polymerase Chain Reaction / Young Adult / Plasmodium falciparum / Antimalarials / Adolescent / Humans / Child / Female / Male / Polymerase Chain Reaction / Young Adult / Plasmodium falciparum / Antimalarials

In Vivo Efficacy of Artemether-Lumefantrine and Chloroquine against Plasmodium vivax: A Randomized Open Label Trial in Central Ethiopia

Survival Analysis / Treatment Outcome / Ethiopia / Adolescent / Multidisciplinary / Prospective studies / Humans / Child / Female / Male / Young Adult / Infant / PLoS one / Aged / Middle Aged / Genotype / Adult / Antimalarials / Chloroquine / Plasmodium Vivax / Primaquine / Prospective studies / Humans / Child / Female / Male / Young Adult / Infant / PLoS one / Aged / Middle Aged / Genotype / Adult / Antimalarials / Chloroquine / Plasmodium Vivax / Primaquine

Antiplasmodial Quinones from Pentas longiflora and Pentas lanceolata

Complementary and Alternative Medicine / Plant Biology / Pharmacognosy / Drug Resistance / Quinones / Rubiaceae / Plant Roots / Anthraquinones / Plant extracts / Plasmodium falciparum / Antimalarials / Rubiaceae / Plant Roots / Anthraquinones / Plant extracts / Plasmodium falciparum / Antimalarials

Antiplasmodial Quinones from Pentas longiflora and Pentas lanceolata

Complementary and Alternative Medicine / Plant Biology / Pharmacognosy / Drug Resistance / Quinones / Rubiaceae / Plant Roots / Anthraquinones / Plant extracts / Plasmodium falciparum / Antimalarials / Rubiaceae / Plant Roots / Anthraquinones / Plant extracts / Plasmodium falciparum / Antimalarials

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