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Antimalarials
Antimalarials
Antiplasmodial Alkaloids from Desmos rostrata
Natural Products / Medicinal Plants / Vietnam / Biological Sciences / Humans / Animals / Alkaloids / CHEMICAL SCIENCES / Plasmodium falciparum / Antimalarials / Natural / KB cells / Molecular Structure / Animals / Alkaloids / CHEMICAL SCIENCES / Plasmodium falciparum / Antimalarials / Natural / KB cells / Molecular Structure
Antiplasmodial Alkaloids from Desmos rostrata
Natural Products / Medicinal Plants / Vietnam / Biological Sciences / Humans / Animals / Alkaloids / CHEMICAL SCIENCES / Plasmodium falciparum / Antimalarials / Natural / KB cells / Molecular Structure / Animals / Alkaloids / CHEMICAL SCIENCES / Plasmodium falciparum / Antimalarials / Natural / KB cells / Molecular Structure
Severe Plasmodium vivax Malaria: A Report on Serial Cases from Bikaner in Northwestern India
Adolescent / India / Humans / Female / Animals / Renal failure / Male / Polymerase Chain Reaction / Acute respiratory distress syndrome / Young Adult / Jaundice / Middle Aged / Immune system / Adult / Antimalarials / World Health Organization / Diagnostic Test / Large Scale / Observational Study / Cerebral Malaria / Epidemiologic Studies / Plasmodium Vivax / The American / Severity of Illness Index / Renal failure / Male / Polymerase Chain Reaction / Acute respiratory distress syndrome / Young Adult / Jaundice / Middle Aged / Immune system / Adult / Antimalarials / World Health Organization / Diagnostic Test / Large Scale / Observational Study / Cerebral Malaria / Epidemiologic Studies / Plasmodium Vivax / The American / Severity of Illness Index
Fumagillin and Fumarranol Interact with P. falciparum Methionine Aminopeptidase 2 and Inhibit Malaria Parasite Growth In Vitro and In Vivo
Organic Chemistry / Malaria / Saccharomyces cerevisiae / Humans / Sequence alignment / Escherichia coli / Mice / Female / Animals / Sesquiterpenes / Plasmodium falciparum / Antimalarials / Protozoan Proteins / Cell Proliferation / Amino Acid Sequence / Chemistry Biology / Recombinant Proteins / Protein Binding / Biochemistry and cell biology / Molecular Sequence Data / Escherichia coli / Mice / Female / Animals / Sesquiterpenes / Plasmodium falciparum / Antimalarials / Protozoan Proteins / Cell Proliferation / Amino Acid Sequence / Chemistry Biology / Recombinant Proteins / Protein Binding / Biochemistry and cell biology / Molecular Sequence Data
Fumagillin and Fumarranol Interact with P. falciparum Methionine Aminopeptidase 2 and Inhibit Malaria Parasite Growth In Vitro and In Vivo
Organic Chemistry / Malaria / Saccharomyces cerevisiae / Humans / Sequence alignment / Escherichia coli / Mice / Female / Animals / Sesquiterpenes / Plasmodium falciparum / Antimalarials / Protozoan Proteins / Cell Proliferation / Amino Acid Sequence / Chemistry Biology / Recombinant Proteins / Protein Binding / Biochemistry and cell biology / Molecular Sequence Data / Escherichia coli / Mice / Female / Animals / Sesquiterpenes / Plasmodium falciparum / Antimalarials / Protozoan Proteins / Cell Proliferation / Amino Acid Sequence / Chemistry Biology / Recombinant Proteins / Protein Binding / Biochemistry and cell biology / Molecular Sequence Data
Fumagillin and Fumarranol Interact with P. falciparum Methionine Aminopeptidase 2 and Inhibit Malaria Parasite Growth In Vitro and In Vivo
Organic Chemistry / Malaria / Saccharomyces cerevisiae / Humans / Sequence alignment / Escherichia coli / Mice / Female / Animals / Sesquiterpenes / Plasmodium falciparum / Antimalarials / Protozoan Proteins / Cell Proliferation / Amino Acid Sequence / Chemistry Biology / Recombinant Proteins / Protein Binding / Biochemistry and cell biology / Molecular Sequence Data / Escherichia coli / Mice / Female / Animals / Sesquiterpenes / Plasmodium falciparum / Antimalarials / Protozoan Proteins / Cell Proliferation / Amino Acid Sequence / Chemistry Biology / Recombinant Proteins / Protein Binding / Biochemistry and cell biology / Molecular Sequence Data
Fumagillin and Fumarranol Interact with P. falciparum Methionine Aminopeptidase 2 and Inhibit Malaria Parasite Growth In Vitro and In Vivo
Organic Chemistry / Malaria / Saccharomyces cerevisiae / Humans / Sequence alignment / Escherichia coli / Mice / Female / Animals / Sesquiterpenes / Plasmodium falciparum / Antimalarials / Protozoan Proteins / Cell Proliferation / Amino Acid Sequence / Chemistry Biology / Recombinant Proteins / Protein Binding / Biochemistry and cell biology / Molecular Sequence Data / Escherichia coli / Mice / Female / Animals / Sesquiterpenes / Plasmodium falciparum / Antimalarials / Protozoan Proteins / Cell Proliferation / Amino Acid Sequence / Chemistry Biology / Recombinant Proteins / Protein Binding / Biochemistry and cell biology / Molecular Sequence Data
Fumagillin and Fumarranol Interact with P. falciparum Methionine Aminopeptidase 2 and Inhibit Malaria Parasite Growth In Vitro and In Vivo
Organic Chemistry / Malaria / Saccharomyces cerevisiae / Humans / Sequence alignment / Escherichia coli / Mice / Female / Animals / Sesquiterpenes / Plasmodium falciparum / Antimalarials / Protozoan Proteins / Cell Proliferation / Amino Acid Sequence / Chemistry Biology / Recombinant Proteins / Protein Binding / Biochemistry and cell biology / Molecular Sequence Data / Escherichia coli / Mice / Female / Animals / Sesquiterpenes / Plasmodium falciparum / Antimalarials / Protozoan Proteins / Cell Proliferation / Amino Acid Sequence / Chemistry Biology / Recombinant Proteins / Protein Binding / Biochemistry and cell biology / Molecular Sequence Data
Fumagillin and Fumarranol Interact with P. falciparum Methionine Aminopeptidase 2 and Inhibit Malaria Parasite Growth In Vitro and In Vivo
Organic Chemistry / Malaria / Saccharomyces cerevisiae / Humans / Sequence alignment / Escherichia coli / Mice / Female / Animals / Sesquiterpenes / Plasmodium falciparum / Antimalarials / Protozoan Proteins / Cell Proliferation / Amino Acid Sequence / Chemistry Biology / Recombinant Proteins / Protein Binding / Biochemistry and cell biology / Molecular Sequence Data / Escherichia coli / Mice / Female / Animals / Sesquiterpenes / Plasmodium falciparum / Antimalarials / Protozoan Proteins / Cell Proliferation / Amino Acid Sequence / Chemistry Biology / Recombinant Proteins / Protein Binding / Biochemistry and cell biology / Molecular Sequence Data
Protein Farnesyltransferase and Protein Prenylation in Plasmodium falciparum
Enzyme Inhibitors / Biological Chemistry / Biological Sciences / Animals / Biological / Enzyme / CHEMICAL SCIENCES / Diterpenes / Substrate Specificity / Plasmodium falciparum / Antimalarials / Amino Acid Profile / Protozoan Proteins / Enzyme / CHEMICAL SCIENCES / Diterpenes / Substrate Specificity / Plasmodium falciparum / Antimalarials / Amino Acid Profile / Protozoan Proteins
Antimalarial Agents from Plants. III. Trichothecenes from Ficus fistulosa and Rhaphidophora decursiva
Complementary and Alternative Medicine / Plant Biology / Pharmacognosy / In Vitro / Animals / STEM / Araceae / Ficus / Bark / Isolation / Plant extracts / Plasmodium falciparum / Antimalarials / Biological activity / Extract / Active Ingredient / Planta / Molecular Structure / Plant Leaves / Terpenoid / STEM / Araceae / Ficus / Bark / Isolation / Plant extracts / Plasmodium falciparum / Antimalarials / Biological activity / Extract / Active Ingredient / Planta / Molecular Structure / Plant Leaves / Terpenoid
Antimalarial Compounds from Rhaphidophora d ecursiva
Natural Products / Medicinal Plants / Vietnam / Magnetic Resonance Spectroscopy / Biological Sciences / Animals / CHEMICAL SCIENCES / Plasmodium falciparum / Antimalarials / Natural / Molecular Conformation / Plant Leaves / Animals / CHEMICAL SCIENCES / Plasmodium falciparum / Antimalarials / Natural / Molecular Conformation / Plant Leaves
Preclinical drug metabolism and pharmacokinetic evaluation of GW844520, a novel anti-malarial mitochondrial electron transport inhibitor
Metabolism / Evaluation / Pharmacokinetics / Drug metabolism / Mitochondria / Dogs / Cell line / Transport / Humans / Permeability / Mice / Pharmaceutical Sciences / Female / Animals / Male / Electron Transport / Bioavailability / Clearance / Rats / Hepatocytes / Antimalarials / Biotransformation / Macaca fascicularis / Protein Binding / Dogs / Cell line / Transport / Humans / Permeability / Mice / Pharmaceutical Sciences / Female / Animals / Male / Electron Transport / Bioavailability / Clearance / Rats / Hepatocytes / Antimalarials / Biotransformation / Macaca fascicularis / Protein Binding
A clinical drug library screen identifies astemizole as an antimalarial agent
Humans / Mice / Animals / Drug Resistance / Plasmodium falciparum / Antimalarials / Plasmodium yoelii / Chloroquine / Biochemistry and cell biology / Antimalarials / Plasmodium yoelii / Chloroquine / Biochemistry and cell biology
A clinical drug library screen identifies astemizole as an antimalarial agent
Humans / Mice / Animals / Drug Resistance / Plasmodium falciparum / Antimalarials / Plasmodium yoelii / Chloroquine / Biochemistry and cell biology / Antimalarials / Plasmodium yoelii / Chloroquine / Biochemistry and cell biology
Dual Molecules as New Antimalarials
Animals / Plasmodium falciparum / Antimalarials / High School Chemistry / Biological activity / Structure activity Relationship / Choline / Pentamidine / Biochemistry and cell biology / Structure activity Relationship / Choline / Pentamidine / Biochemistry and cell biology
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