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Antimalarials

No Evidence of Delayed Parasite Clearance after Oral Artesunate Treatment of Uncomplicated Falciparum Malaria in Mali

Mali / Humans / Child / Female / Male / Infant / Antimalarials / The American / Child preschool / Infant / Antimalarials / The American / Child preschool

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Open label randomized comparison of dihydroartemisinin-piperaquine and artesunate-amodiaquine for the treatment of uncomplicated Plasmodium falciparum malaria in central Vietnam

Tropical Medicine / Treatment / Treatment Outcome / Vietnam / Adolescent / Comparative Study / Tropical medicine (Health Sciences) / Humans / Child / Female / Therapy / Drug Resistance / Classification / Male / Young Adult / Middle Aged / Adult / Public health systems and services research / Plasmodium falciparum / Antimalarials / Combination drug therapy / Quinolines / Pilot Projects / Genotypes / Amodiaquine / Age Groups / Multiple Drug Resistance / Child preschool / Comparative Study / Tropical medicine (Health Sciences) / Humans / Child / Female / Therapy / Drug Resistance / Classification / Male / Young Adult / Middle Aged / Adult / Public health systems and services research / Plasmodium falciparum / Antimalarials / Combination drug therapy / Quinolines / Pilot Projects / Genotypes / Amodiaquine / Age Groups / Multiple Drug Resistance / Child preschool

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A comprehensive survey of polymorphisms conferring anti-malarial resistance in Plasmodium falciparum across Pakistan

Medical Microbiology / Pakistan / Malaria / Adolescent / Humans / Child / Female / Drug Resistance / Male / Polymerase Chain Reaction / Young Adult / Infant / Gene Dosage / Aged / Middle Aged / Genotype / Adult / Plasmodium falciparum / Antimalarials / Protozoan Proteins / Amino Acid Substitution Rates / Child preschool / Child / Female / Drug Resistance / Male / Polymerase Chain Reaction / Young Adult / Infant / Gene Dosage / Aged / Middle Aged / Genotype / Adult / Plasmodium falciparum / Antimalarials / Protozoan Proteins / Amino Acid Substitution Rates / Child preschool

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Design and Synthesis of Endoperoxide Antimalarial Prodrug Models

English / Prodrugs / Drug Design / Chalcones / CHEMICAL SCIENCES / Antimalarials / Cysteine Proteinase Inhibitors / Antimalarials / Cysteine Proteinase Inhibitors

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An Endoperoxide-Based Hybrid Approach to Deliver Falcipain Inhibitors Inside Malaria Parasites

Organic Chemistry / Malaria / Humans / Drug Resistance / Hybrids / Plasmodium falciparum / Antimalarials / Cysteine endopeptidases / Chloroquine / Structure activity Relationship / Erythrocytes / Hemoglobins / Cysteine Proteinase Inhibitors / Plasmodium falciparum / Antimalarials / Cysteine endopeptidases / Chloroquine / Structure activity Relationship / Erythrocytes / Hemoglobins / Cysteine Proteinase Inhibitors

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Aminocyclopropanes as precursors of endoperoxides with antimalarial activity

Organic Chemistry / Macromolecular X-Ray Crystallography / Amines / Amides / Plasmodium falciparum / Antimalarials / Structure activity Relationship / Oxidation-Reduction / Molecular Structure / Antimalarials / Structure activity Relationship / Oxidation-Reduction / Molecular Structure

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Protein Farnesyltransferase and Protein Prenylation in Plasmodium falciparum

Enzyme Inhibitors / Biological Chemistry / Biological Sciences / Animals / Biological / Enzyme / CHEMICAL SCIENCES / Diterpenes / Substrate Specificity / Plasmodium falciparum / Antimalarials / Amino Acid Profile / Protozoan Proteins / Enzyme / CHEMICAL SCIENCES / Diterpenes / Substrate Specificity / Plasmodium falciparum / Antimalarials / Amino Acid Profile / Protozoan Proteins

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Protein Farnesyltransferase Inhibitors Exhibit Potent Antimalarial Activity

Organic Chemistry / Medicinal Chemistry / Fluorescence Microscopy / Malaria / Treatment / In Vitro / Humans / Mice / Female / Animals / Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis / Quinolones / In Vivo / Rats / Medicinal / Plasmodium falciparum / Antimalarials / Structure activity Relationship / Erythrocytes / Chemical Synthesis / Plasmodium berghei / In Vitro / Humans / Mice / Female / Animals / Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis / Quinolones / In Vivo / Rats / Medicinal / Plasmodium falciparum / Antimalarials / Structure activity Relationship / Erythrocytes / Chemical Synthesis / Plasmodium berghei

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Protein farnesyltransferase inhibitors exhibit potent antimalarial activity

Organic Chemistry / Medicinal Chemistry / Fluorescence Microscopy / Malaria / Treatment / In Vitro / Humans / Mice / Female / Animals / Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis / Quinolones / In Vivo / Rats / Medicinal / Plasmodium falciparum / Antimalarials / Structure activity Relationship / Erythrocytes / Chemical Synthesis / Plasmodium berghei / In Vitro / Humans / Mice / Female / Animals / Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis / Quinolones / In Vivo / Rats / Medicinal / Plasmodium falciparum / Antimalarials / Structure activity Relationship / Erythrocytes / Chemical Synthesis / Plasmodium berghei

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Synthesis and antimalarial and antituberculosis activities of a series of natural and unnatural 4-methoxy-6-styryl-pyran-2-ones, dihydro analogues and photo-dimers

Organic Chemistry / Light / Coumarins / Plasmodium falciparum / Antimalarials / Bioorganic and medicinal Chemistry / Molecular Structure / Dimerization / Bioorganic and medicinal Chemistry / Molecular Structure / Dimerization

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Thiamin deficiency and uncomplicated falciparum malaria in Laos

Tropical Medicine / Treatment Outcome / Adolescent / Tropical medicine (Health Sciences) / LAOS / Humans / Child / Female / Male / Infant / Sesquiterpenes / Aged / Middle Aged / Pyrimethamine / Sulfadoxine / Adult / Public health systems and services research / Antimalarials / Deficiency / Combination drug therapy / Chloroquine / Deficit / Erythrocytes / Child preschool / Humans / Child / Female / Male / Infant / Sesquiterpenes / Aged / Middle Aged / Pyrimethamine / Sulfadoxine / Adult / Public health systems and services research / Antimalarials / Deficiency / Combination drug therapy / Chloroquine / Deficit / Erythrocytes / Child preschool

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Antiplasmodial activity of aporphine alkaloids and sesquiterpene lactones from Liriodendron tulipifera L

Complementary and Alternative Medicine / Plant Biology / Malaria / Ethnopharmacology / Pharmacognosy / Cytotoxicity / Phytotherapy / Antimalarial / United States / Alkaloids / Sesquiterpenes / Lancet / Plant extracts / Liriodendron / Antimalarials / Lactones / Plant Leaves / Terpenoid / Cytotoxicity / Phytotherapy / Antimalarial / United States / Alkaloids / Sesquiterpenes / Lancet / Plant extracts / Liriodendron / Antimalarials / Lactones / Plant Leaves / Terpenoid

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Bioactive alkaloids from Brunsvigia radulosa

Phytochemistry / Medicinal Plants / Magnetic Resonance Spectroscopy / Biological Sciences / Mice / Animals / Alkaloids / CHEMICAL SCIENCES / Plasmodium falciparum / Antimalarials / Animals / Alkaloids / CHEMICAL SCIENCES / Plasmodium falciparum / Antimalarials

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N -Aryl-2-aminobenzimidazoles: Novel, Efficacious, Antimalarial Lead Compounds

Pharmacology / Chemistry / Organic Chemistry / Pharmacy / Medicinal Chemistry / Malaria / Humans / Animals / Rats / Hepatocytes / Plasmodium falciparum / Antimalarials / Benzimidazoles / Structure activity Relationship / Plasmodium berghei / Malaria / Humans / Animals / Rats / Hepatocytes / Plasmodium falciparum / Antimalarials / Benzimidazoles / Structure activity Relationship / Plasmodium berghei

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Amino derivatives of indolone-N-oxide: Preparation and antiplasmodial properties

Organic Chemistry / Mass Spectrometry / Magnetic Resonance Spectroscopy / Animals / Plasmodium falciparum / Antimalarials / Oxides / Antimalarials / Oxides

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A comprehensive survey of polymorphisms conferring anti-malarial resistance in Plasmodium falciparum across Pakistan

Medical Microbiology / Pakistan / Malaria / Adolescent / Humans / Child / Female / Drug Resistance / Male / Polymerase Chain Reaction / Young Adult / Infant / Gene Dosage / Aged / Middle Aged / Genotype / Adult / Plasmodium falciparum / Antimalarials / Protozoan Proteins / Amino Acid Substitution Rates / Child preschool / Child / Female / Drug Resistance / Male / Polymerase Chain Reaction / Young Adult / Infant / Gene Dosage / Aged / Middle Aged / Genotype / Adult / Plasmodium falciparum / Antimalarials / Protozoan Proteins / Amino Acid Substitution Rates / Child preschool

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