Antimalarials - Page 8

The antimalarial action of desferal involves a direct access route to erythrocytic (Plasmodium falciparum) parasites

Kinetics / Humans / Animals / Plasmodium falciparum / Antimalarials / Erythrocyte Membrane / Erythrocytes / Drug Carriers / Clinical Investigation / Molecular Structure / Erythrocyte Membrane / Erythrocytes / Drug Carriers / Clinical Investigation / Molecular Structure

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Antiparasitic activities of novel ruthenium/lapachol complexes

Inorganic Chemistry / Leishmania / Macromolecular X-Ray Crystallography / Humans / Mice / Animals / Naphthoquinones / Plasmodium falciparum / Antimalarials / Molecular Conformation / Trypanocidal Agents / Inorganic Biochemistry / Animals / Naphthoquinones / Plasmodium falciparum / Antimalarials / Molecular Conformation / Trypanocidal Agents / Inorganic Biochemistry

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Antiparasitic activities of novel ruthenium/lapachol complexes

Inorganic Chemistry / Leishmania / Macromolecular X-Ray Crystallography / Humans / Mice / Animals / Naphthoquinones / Plasmodium falciparum / Antimalarials / Molecular Conformation / Trypanocidal Agents / Inorganic Biochemistry / Animals / Naphthoquinones / Plasmodium falciparum / Antimalarials / Molecular Conformation / Trypanocidal Agents / Inorganic Biochemistry

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Identification of a nucleoside/nucleobase transporter from Plasmodium falciparum, a novel target for anti-malarial chemotherapy

Kinetics / Biological Sciences / Phylogeny / Xenopus / Animals / Biochemical / CHEMICAL SCIENCES / Molecular cloning / Protein Secondary Structure Prediction / Time Factors / Substrate Specificity / Plasmodium falciparum / Antimalarials / Protozoan Proteins / Amino Acid Sequence / Nucleosides / Cations / Hydrogen-Ion Concentration / Adenine / Biochemical / CHEMICAL SCIENCES / Molecular cloning / Protein Secondary Structure Prediction / Time Factors / Substrate Specificity / Plasmodium falciparum / Antimalarials / Protozoan Proteins / Amino Acid Sequence / Nucleosides / Cations / Hydrogen-Ion Concentration / Adenine

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Impaired fitness of drug-resistant malaria parasites: evidence and implication on drug-deployment policies

Malaria / Folic acid / Plasmodium / Humans / Mutation / Animals / Drug Resistance / Host-parasite interactions / Biological evolution / Clinical Sciences / Antimalarials / Animals / Drug Resistance / Host-parasite interactions / Biological evolution / Clinical Sciences / Antimalarials

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Evidence of Plasmodium falciparum malaria resistant to atovaquone and proguanil hydrochloride: case reports

British medical history / Case Report / Humans / Female / Drug Resistance / Male / Infant / Naphthoquinones / High Pressure Liquid Chromatography / Public health systems and services research / ATOVAQUONE / Plasmodium falciparum / Antimalarials / BMJ / Tablets / Combination drug therapy / Male / Infant / Naphthoquinones / High Pressure Liquid Chromatography / Public health systems and services research / ATOVAQUONE / Plasmodium falciparum / Antimalarials / BMJ / Tablets / Combination drug therapy

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Case report: An unusual late relapse of Plasmodium vivax malaria

Case Report / Humans / Infection Control / Animals / Male / Polymerase Chain Reaction / Differential Diagnosis / Recurrence / Middle Aged / Antimalarials / Blood Transfusion / Chloroquine / Plasmodium Vivax / Primaquine / The American / Polymerase Chain Reaction / Differential Diagnosis / Recurrence / Middle Aged / Antimalarials / Blood Transfusion / Chloroquine / Plasmodium Vivax / Primaquine / The American

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Antimalarial Pyrido[1,2- a ]benzimidazoles

Organic Chemistry / Medicinal Chemistry / Malaria / Humans / Mice / Animals / Male / Rats / Plasmodium falciparum / Antimalarials / Pyridines / Benzimidazoles / Structure activity Relationship / Plasmodium berghei / Animals / Male / Rats / Plasmodium falciparum / Antimalarials / Pyridines / Benzimidazoles / Structure activity Relationship / Plasmodium berghei

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Preclinical drug metabolism and pharmacokinetic evaluation of GW844520, a novel anti-malarial mitochondrial electron transport inhibitor

Drug metabolism / Dogs / Cell line / Humans / Mice / Pharmaceutical Sciences / Female / Animals / Male / Electron Transport / Rats / Hepatocytes / Antimalarials / Biotransformation / Macaca fascicularis / Protein Binding / Pharmaceutical Sciences / Female / Animals / Male / Electron Transport / Rats / Hepatocytes / Antimalarials / Biotransformation / Macaca fascicularis / Protein Binding

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No Evidence of Delayed Parasite Clearance after Oral Artesunate Treatment of Uncomplicated Falciparum Malaria in Mali

Mali / Humans / Child / Female / Male / Infant / Antimalarials / The American / Infant / Antimalarials / The American

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Antiplasmodial activity of extracts from seven medicinal plants used in malaria treatment in Cameroon

Complementary and Alternative Medicine / Plant Biology / Cameroon / Ethnopharmacology / Medicinal Plants / Phytotherapy / Animals / Plant extracts / Angiosperms / Euphorbiaceae / Plasmodium falciparum / Antimalarials / Cysteine endopeptidases / Biological activity / Erythrocytes / Annonaceae / Moraceae / Medicinal Plant / Phytotherapy / Animals / Plant extracts / Angiosperms / Euphorbiaceae / Plasmodium falciparum / Antimalarials / Cysteine endopeptidases / Biological activity / Erythrocytes / Annonaceae / Moraceae / Medicinal Plant

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Preliminary pharmaceutical development of antimalarial-antibiotic cotherapy as a pre-referral paediatric treatment of fever in malaria endemic areas

Malaria / Pharmaceutical Technology / Powder Diffraction / Crystallization / Pharmaceutical Chemistry / Macromolecular X-Ray Crystallography / Pharmaceutics / Humans / Animals / Endemic Diseases / Solubility / Anti-Bacterial Agents / Antimalarials / Tablets / Age Factors / Rabbits / Azithromycin / Capsules / Excipients / Biological Availability / Macromolecular X-Ray Crystallography / Pharmaceutics / Humans / Animals / Endemic Diseases / Solubility / Anti-Bacterial Agents / Antimalarials / Tablets / Age Factors / Rabbits / Azithromycin / Capsules / Excipients / Biological Availability

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N -Aryl-2-aminobenzimidazoles: Novel, Efficacious, Antimalarial Lead Compounds

Pharmacology / Chemistry / Organic Chemistry / Pharmacy / Medicinal Chemistry / Malaria / Humans / Animals / Rats / Hepatocytes / Plasmodium falciparum / Antimalarials / Benzimidazoles / Structure activity Relationship / Plasmodium berghei / Malaria / Humans / Animals / Rats / Hepatocytes / Plasmodium falciparum / Antimalarials / Benzimidazoles / Structure activity Relationship / Plasmodium berghei

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Statistical Model To Evaluate In Vivo Activities of Antimalarial Drugs in a Plasmodium cynomolgi-Macaque Model for Plasmodium vivax Malaria

Microbiology / Medical Microbiology / Drug development / Prodrugs / Mixed Effects Models / Female / Animals / Drug Resistance / Male / Animal Model / South America / Animal Experimentation / Antimalarials / Rhesus macaques / Antimicrobial agents / Macaca Mulatta / Sub Saharan Africa / Statistical Model / Mechanism of action / Host Range / Plasmodium Vivax / Treatment Effect / Female / Animals / Drug Resistance / Male / Animal Model / South America / Animal Experimentation / Antimalarials / Rhesus macaques / Antimicrobial agents / Macaca Mulatta / Sub Saharan Africa / Statistical Model / Mechanism of action / Host Range / Plasmodium Vivax / Treatment Effect

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Dual Molecules as New Antimalarials

Animals / Plasmodium falciparum / Antimalarials / High School Chemistry / Biological activity / Structure activity Relationship / Choline / Pentamidine / Biochemistry and cell biology / Structure activity Relationship / Choline / Pentamidine / Biochemistry and cell biology

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Transgenic Anopheles gambiae Expressing an Antimalarial Peptide Suffer No Significant Fitness Cost

Fertility / Multidisciplinary / Longevity / Sex ratio / Female / Animals / Male / Peptides / Feeding Behavior / PLoS one / Anopheles gambiae / Larva / Antimalarials / Genetic Fitness / Animals / Male / Peptides / Feeding Behavior / PLoS one / Anopheles gambiae / Larva / Antimalarials / Genetic Fitness

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