Macromolecular X-Ray Crystallography - Page 8

Antimicrobial Compounds from Petalostemum purpureum

Natural Products / Fungi / Magnetic Resonance Spectroscopy / Flavonoids / Macromolecular X-Ray Crystallography / Biological Sciences / Methylation / High Performance Liquid Chromatography / Gram Positive Bacteria / CHEMICAL SCIENCES / Gram-negative bacteria / Anti-Bacterial Agents / Plant extracts / Natural / Acetylation / Microbial Sensitivity Tests / Biological Sciences / Methylation / High Performance Liquid Chromatography / Gram Positive Bacteria / CHEMICAL SCIENCES / Gram-negative bacteria / Anti-Bacterial Agents / Plant extracts / Natural / Acetylation / Microbial Sensitivity Tests

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A Common Single Nucleotide Polymorphism in Endoplasmic Reticulum Aminopeptidase 2 Induces a Specificity Switch That Leads to Altered Antigen Processing

Immunology / Immunology of the Gut / Macromolecular X-Ray Crystallography / Humans / Endoplasmic Reticulum / Antigen Presentation / HeLa cells / Substrate Specificity / Genetic variation / Amino Acid Sequence / Molecular Sequence Data / Antigen Presentation / HeLa cells / Substrate Specificity / Genetic variation / Amino Acid Sequence / Molecular Sequence Data

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Engineering the Exo-loop of Trichoderma reesei Cellobiohydrolase, Cel7A. A comparison with Phanerochaete chrysosporium Cel7D

Molecular Biology / Protein Engineering / Macromolecular X-Ray Crystallography / Glycoside hydrolase / Molecular / Crystal structure / Sequence alignment / Mutation / Trichoderma / Enzyme / Hydrogen Bond / Active site / Protein Secondary Structure Prediction / Amino Acid Sequence / Protein Denaturation / Conformational Change / Microcrystalline Cellulose / Biochemistry and cell biology / Molecular Sequence Data / Crystal structure / Sequence alignment / Mutation / Trichoderma / Enzyme / Hydrogen Bond / Active site / Protein Secondary Structure Prediction / Amino Acid Sequence / Protein Denaturation / Conformational Change / Microcrystalline Cellulose / Biochemistry and cell biology / Molecular Sequence Data

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A Structural Model of Transcription Elongation

Science / RNA polymerase / Gene expression / Multidisciplinary / Macromolecular X-Ray Crystallography / Transcription / DNA / Mutation / Nucleic acid hybridization / Bacteria / DNA hybridization / Mechanism / Elongation / Enzyme activity / Protein Conformation / Crystalline Structure / Nucleic Acid Conformation / Structural model / Nucleic Acid / single stranded DNA / Functional Properties / Transcription / DNA / Mutation / Nucleic acid hybridization / Bacteria / DNA hybridization / Mechanism / Elongation / Enzyme activity / Protein Conformation / Crystalline Structure / Nucleic Acid Conformation / Structural model / Nucleic Acid / single stranded DNA / Functional Properties

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Trapping of a Transcription Complex Using a New Nucleotide Analogue: AMP Aluminium Fluoride

Molecular Biology / RNA polymerase / Macromolecular X-Ray Crystallography / Transcription / Crystal structure / Fluorides / X ray diffraction / Bound States / Sinorhizobium meliloti / S100 protein family / Protein Binding / Organometallic Compounds / AAA / Nucleotides / Biochemistry and cell biology / Adenosine monophosphate / Adenosine Diphosphate / Fluorides / X ray diffraction / Bound States / Sinorhizobium meliloti / S100 protein family / Protein Binding / Organometallic Compounds / AAA / Nucleotides / Biochemistry and cell biology / Adenosine monophosphate / Adenosine Diphosphate

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Organometallic 3-(1 H -Benzimidazol-2-yl)-1 H -pyrazolo[3,4- b ]pyridines as Potential Anticancer Agents

Chemical Engineering / Chemistry / Inorganic Chemistry / Cell Cycle / Inorganic / Macromolecular X-Ray Crystallography / Humans / Neoplasms / Pyridines / Organometallic Compounds / Cell Survival / Antineoplastic Agents / Macromolecular X-Ray Crystallography / Humans / Neoplasms / Pyridines / Organometallic Compounds / Cell Survival / Antineoplastic Agents

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N -Propargylamides via the Asymmetric Michael Addition of B -Alkynyl-10-TMS-9- borabicyclo[3.3.2]decanes to N -Acylimines

Macromolecular X-Ray Crystallography / CHEMICAL SCIENCES / Amides / Ephedrine / Boron Compounds / Alkynes / Molecular Structure / Alkynes / Molecular Structure

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Two enantiomerically pure cyclic arenesulfonamide hydrochloride salts

Inorganic Chemistry / Macromolecular X-Ray Crystallography / Hydrogen Bonding / Salts / Thiazines

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Insights into Aurora-A Kinase Activation Using Unnatural Amino Acids Incorporated by Chemical Modification

Biology / Medicine / Macromolecular X-Ray Crystallography / Biological Sciences / Humans / Phosphorylation / CHEMICAL SCIENCES / Amino Acids / Phosphorylation / CHEMICAL SCIENCES / Amino Acids

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Poly Specific trans -Acyltransferase Machinery Revealed via Engineered Acyl-CoA Synthetases

Natural Products / Biosynthesis of Natural Products / Macromolecular X-Ray Crystallography / Biological Sciences / High Performance Liquid Chromatography / CHEMICAL SCIENCES / Molecular cloning / Substrate Specificity / Polyketides / Genetic variation / Enzyme Engineering / Recombinant Proteins / CHEMICAL SCIENCES / Molecular cloning / Substrate Specificity / Polyketides / Genetic variation / Enzyme Engineering / Recombinant Proteins

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Autoproteolysis and Intramolecular Dissociation of Yersinia YscU Precedes Secretion of Its C-Terminal Polypeptide YscUCC

Kinetics / Calcium / Multidisciplinary / Macromolecular X-Ray Crystallography / Protein Stability / Mutation / Temperature / Peptides / PLoS one / CHEMICAL SCIENCES / Densitometry / Hydrogen-Ion Concentration / Yersinia pseudotuberculosis / Mutation / Temperature / Peptides / PLoS one / CHEMICAL SCIENCES / Densitometry / Hydrogen-Ion Concentration / Yersinia pseudotuberculosis

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Physicochemical and biopharmaceutical characterization ofendo-2-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2,3-dihydro-1H-benz[e]isoindol-1-one (CR3124) a novel potent 5-HT3 receptor antagonist

Water / NMR Spectroscopy / Crystallization / Macromolecular X-Ray Crystallography / Molecular Dynamics / Crystal structure / Humans / Differential scanning calorimetry / Permeability / Pharmaceutical Sciences / Solubility / Intestinal absorption / Caco-2 cells / Molecular Conformation / Crystalline Structure / Serotonin antagonists / Crystal structure / Humans / Differential scanning calorimetry / Permeability / Pharmaceutical Sciences / Solubility / Intestinal absorption / Caco-2 cells / Molecular Conformation / Crystalline Structure / Serotonin antagonists

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Protein Sequences Yield a Proteomic Code

Caenorhabditis elegans / Protein Folding / Proteomics / Polymers / Macromolecular X-Ray Crystallography / Escherichia coli / Animals / Peptides / Proteins / Protein Conformation / Amino Acid Sequence / Proteome / Biochemistry and cell biology / Molecular Sequence Data / Escherichia coli / Animals / Peptides / Proteins / Protein Conformation / Amino Acid Sequence / Proteome / Biochemistry and cell biology / Molecular Sequence Data

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Aminocyclopropanes as precursors of endoperoxides with antimalarial activity

Organic Chemistry / Macromolecular X-Ray Crystallography / Amines / Amides / Plasmodium falciparum / Antimalarials / Structure activity Relationship / Oxidation-Reduction / Molecular Structure / Antimalarials / Structure activity Relationship / Oxidation-Reduction / Molecular Structure

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New Supramolecular Au I –Cu I Complex as Potential Luminescent Label for Proteins

Chemical Engineering / Inorganic Chemistry / Magnetic Resonance Spectroscopy / Macromolecular X-Ray Crystallography / Antibodies / Humans / Gold / Copper / Animals / Proteins / Rabbits / Molecular Structure / Chymotrypsin / Serum albumin / Humans / Gold / Copper / Animals / Proteins / Rabbits / Molecular Structure / Chymotrypsin / Serum albumin

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6-Amino-4-(pyrimidin-4-yl)pyridones: Novel glycogen synthase kinase-3β inhibitors

Organic Chemistry / Pharmacokinetics / Macromolecular X-Ray Crystallography / In Vitro / Humans / High throughput screening / Central Nervous System / In Vivo / Rat / Bioorganic and medicinal Chemistry / Structure activity Relationship / Chemical Synthesis / Protein Kinase Inhibitors / Molecular Structure / High throughput screening / Central Nervous System / In Vivo / Rat / Bioorganic and medicinal Chemistry / Structure activity Relationship / Chemical Synthesis / Protein Kinase Inhibitors / Molecular Structure

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