Macromolecular X-Ray Crystallography - Page 7

New Supramolecular Au I –Cu I Complex as Potential Luminescent Label for Proteins

Chemical Engineering / Inorganic Chemistry / Magnetic Resonance Spectroscopy / Macromolecular X-Ray Crystallography / Antibodies / Humans / Gold / Copper / Animals / Proteins / Rabbits / Molecular Structure / Chymotrypsin / Serum albumin / Humans / Gold / Copper / Animals / Proteins / Rabbits / Molecular Structure / Chymotrypsin / Serum albumin

Download

New Supramolecular Au I –Cu I Complex as Potential Luminescent Label for Proteins

Chemical Engineering / Inorganic Chemistry / Magnetic Resonance Spectroscopy / Macromolecular X-Ray Crystallography / Antibodies / Humans / Gold / Copper / Animals / Proteins / Rabbits / Molecular Structure / Chymotrypsin / Serum albumin / Humans / Gold / Copper / Animals / Proteins / Rabbits / Molecular Structure / Chymotrypsin / Serum albumin

Download

“Jumping Crystals”: Oxygen-Evolving Metal-Nitroxide Complexes

Chemical Engineering / Inorganic Chemistry / Inorganic / Macromolecular X-Ray Crystallography / Motion / Metals / Magnetics / Oxygen / Imidazoles / Nitrogen Oxides / Ligands / Molecular Structure / Metals / Magnetics / Oxygen / Imidazoles / Nitrogen Oxides / Ligands / Molecular Structure

Download

Preliminary pharmaceutical development of antimalarial–antibiotic cotherapy as a pre-referral paediatric treatment of fever in malaria endemic areas

Malaria / Pharmaceutical Technology / Powder Diffraction / Crystallization / Pharmaceutical Chemistry / Macromolecular X-Ray Crystallography / Pharmaceutics / Humans / Animals / Endemic Diseases / Solubility / Anti-Bacterial Agents / Antimalarials / Tablets / Age Factors / Rabbits / Azithromycin / Capsules / Excipients / Biological Availability / Macromolecular X-Ray Crystallography / Pharmaceutics / Humans / Animals / Endemic Diseases / Solubility / Anti-Bacterial Agents / Antimalarials / Tablets / Age Factors / Rabbits / Azithromycin / Capsules / Excipients / Biological Availability

Download

Engineering the Exo-loop of Trichoderma reesei Cellobiohydrolase, Cel7A. A comparison with Phanerochaete chrysosporium Cel7D

Molecular Biology / Protein Engineering / Macromolecular X-Ray Crystallography / Molecular / Sequence alignment / Mutation / Trichoderma / Enzyme / Hydrogen Bond / Active site / Protein Secondary Structure Prediction / Amino Acid Sequence / Protein Denaturation / Conformational Change / Microcrystalline Cellulose / Biochemistry and cell biology / Mutation / Trichoderma / Enzyme / Hydrogen Bond / Active site / Protein Secondary Structure Prediction / Amino Acid Sequence / Protein Denaturation / Conformational Change / Microcrystalline Cellulose / Biochemistry and cell biology

Download

Structural Insights into Antibody Recognition of Mycobacterial Polysaccharides

Molecular Biology / Macromolecular X-Ray Crystallography / Molecular / Tuberculosis / Mycobacterium / Mice / Animals / Monoclonal Antibodies / Lipopolysaccharides / Amino Acid Sequence / Protein Binding / Biochemistry and cell biology / Branch point / Mice / Animals / Monoclonal Antibodies / Lipopolysaccharides / Amino Acid Sequence / Protein Binding / Biochemistry and cell biology / Branch point

Download

Homoleptic diphosphacyclobutadiene complexes [M(Î· 4-P2C2R2)2]x- (M=Fe, Co; X=0, 1)

Mass Spectrometry / Cyclic Voltammetry / Magnetic Resonance Spectroscopy / Macromolecular X-Ray Crystallography / Phosphorus / Iron / Cobalt / Organophosphorus Compounds / CHEMICAL SCIENCES / Metal ion / Molecular Conformation / Organometallic Compounds / X Ray Crystallography / Oxidation-Reduction / Molecular Structure / Iron / Cobalt / Organophosphorus Compounds / CHEMICAL SCIENCES / Metal ion / Molecular Conformation / Organometallic Compounds / X Ray Crystallography / Oxidation-Reduction / Molecular Structure

Download

Discovery of 5-[[4-[(2,3-Dimethyl-2 H -indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide (Pazopanib), a Novel and Potent Vascular Endothelial Growth Factor Receptor Inhibitor †

Organic Chemistry / Medicinal Chemistry / Pharmacokinetics / Macromolecular X-Ray Crystallography / Cell line / In Vitro / Humans / Cancer Therapy / Mice / Animals / VEGFR / In Vivo / Endothelial cell / Isoenzymes / Medicinal / Neoplasms / Biological activity / Isozyme / Protein Kinase Inhibitors / Molecular Structure / Vascular Endothelial Growth Factor / Growth factor receptor / Vascular endothelial growth factor receptor / In Vitro / Humans / Cancer Therapy / Mice / Animals / VEGFR / In Vivo / Endothelial cell / Isoenzymes / Medicinal / Neoplasms / Biological activity / Isozyme / Protein Kinase Inhibitors / Molecular Structure / Vascular Endothelial Growth Factor / Growth factor receptor / Vascular endothelial growth factor receptor

Download

Asteropsin A: An unusual cystine-crosslinked peptide from porifera enhances neuronal Ca2+ influx

Protein Folding / Kinetics / Calcium / Magnetic Resonance Spectroscopy / Porifera / Macromolecular X-Ray Crystallography / Biological Sciences / Cerebral Cortex / Mice / Animals / Physical sciences / Peptides / Neurons / Voltage-Gated Sodium Channels / Primary Cell Culture / Protein Conformation / Amino Acid Sequence / Ion Transport / Action Potentials / Biochemistry and cell biology / Macromolecular X-Ray Crystallography / Biological Sciences / Cerebral Cortex / Mice / Animals / Physical sciences / Peptides / Neurons / Voltage-Gated Sodium Channels / Primary Cell Culture / Protein Conformation / Amino Acid Sequence / Ion Transport / Action Potentials / Biochemistry and cell biology

Download

Response to Copper Stress in Streptomyces lividans Extends beyond Genes under Direct Control of a Copper-sensitive Operon Repressor Protein (CsoR)

Biological Chemistry / Macromolecular X-Ray Crystallography / Biological Sciences / Copper / CHEMICAL SCIENCES / Physiological Stress Markers

Download

Copper (II) Complexes of [1,2,4]Triazolo [1,5-a]Pyrimidine Derivatives as Potential Anti-Parasitic Agents

Drug metabolism / Macrophages / Leishmania / Magnetic Resonance Spectroscopy / Macromolecular X-Ray Crystallography / Energy Metabolism / Cercopithecus aethiops / Copper / Mice / Animals / Drug Design / Trypanosoma Cruzi / Triazoles / NAD / Organometallic Compounds / Vero cells / Energy Metabolism / Cercopithecus aethiops / Copper / Mice / Animals / Drug Design / Trypanosoma Cruzi / Triazoles / NAD / Organometallic Compounds / Vero cells

Download

Mechanism of phosphoryl transfer by nucleoside diphosphate kinase

Catalysis / Kinetics / Macromolecular X-Ray Crystallography / Phosphorus / Animals / Dictyostelium / Active site / Lysine / Nucleoside Diphosphate Kinase / Protein Conformation / Structure activity Relationship / Hydrogen-Ion Concentration / Asparagine / Site-directed Mutagenesis / Tyrosine / Biochemistry and cell biology / Adenosine Triphosphate / Dictyostelium / Active site / Lysine / Nucleoside Diphosphate Kinase / Protein Conformation / Structure activity Relationship / Hydrogen-Ion Concentration / Asparagine / Site-directed Mutagenesis / Tyrosine / Biochemistry and cell biology / Adenosine Triphosphate

Download

Discovery of 5-[[4-[(2,3-Dimethyl-2 H -indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide (Pazopanib), a Novel and Potent Vascular Endothelial Growth Factor Receptor Inhibitor †

Organic Chemistry / Medicinal Chemistry / Pharmacokinetics / Macromolecular X-Ray Crystallography / Cell line / In Vitro / Humans / Cancer Therapy / Mice / Animals / VEGFR / In Vivo / Endothelial cell / Isoenzymes / Medicinal / Neoplasms / Biological activity / Isozyme / Protein Kinase Inhibitors / Molecular Structure / Vascular Endothelial Growth Factor / Growth factor receptor / Vascular endothelial growth factor receptor / In Vitro / Humans / Cancer Therapy / Mice / Animals / VEGFR / In Vivo / Endothelial cell / Isoenzymes / Medicinal / Neoplasms / Biological activity / Isozyme / Protein Kinase Inhibitors / Molecular Structure / Vascular Endothelial Growth Factor / Growth factor receptor / Vascular endothelial growth factor receptor

Download

N-(Sulfonamido)alkyl[tetrahydro-1H-benzo[e]indol-2-yl]amines: potent antagonists of human neuropeptide Y Y5 receptor

Organic Chemistry / Macromolecular X-Ray Crystallography / Humans / Neuropeptide Y / Bioorganic and medicinal Chemistry / Molecular Structure

Download

Homoleptic diphosphacyclobutadiene complexes [M(Î· 4-P2C2R2)2]x- (M=Fe, Co; X=0, 1)

Mass Spectrometry / Cyclic Voltammetry / Magnetic Resonance Spectroscopy / Macromolecular X-Ray Crystallography / Phosphorus / Iron / Cobalt / Organophosphorus Compounds / CHEMICAL SCIENCES / Metal ion / Molecular Conformation / Organometallic Compounds / X Ray Crystallography / Oxidation-Reduction / Molecular Structure / Iron / Cobalt / Organophosphorus Compounds / CHEMICAL SCIENCES / Metal ion / Molecular Conformation / Organometallic Compounds / X Ray Crystallography / Oxidation-Reduction / Molecular Structure

Download

Engineering the Exo-loop of Trichoderma reesei Cellobiohydrolase, Cel7A. A comparison with Phanerochaete chrysosporium Cel7D

Molecular Biology / Protein Engineering / Macromolecular X-Ray Crystallography / Molecular / Sequence alignment / Mutation / Trichoderma / Enzyme / Hydrogen Bond / Active site / Protein Secondary Structure Prediction / Amino Acid Sequence / Protein Denaturation / Conformational Change / Microcrystalline Cellulose / Biochemistry and cell biology / Molecular Sequence Data / Mutation / Trichoderma / Enzyme / Hydrogen Bond / Active site / Protein Secondary Structure Prediction / Amino Acid Sequence / Protein Denaturation / Conformational Change / Microcrystalline Cellulose / Biochemistry and cell biology / Molecular Sequence Data

Download