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Macromolecular X-Ray Crystallography
Macromolecular X-Ray Crystallography
Curvularides A-E: Antifungal Hybrid Peptide-Polyketides from the Endophytic Fungus Curvularia geniculata
Fungi / Macromolecular X-Ray Crystallography / Animals / Fluconazole / Candida albicans / Peptides / CHEMICAL SCIENCES / Chimera / Antifungal Agents / Peptides / CHEMICAL SCIENCES / Chimera / Antifungal Agents
Uracil-DNA glycosylase-DNA substrate and product structures: Conformational strain promotes catalytic efficiency by coupled stereoelectronic effects
Catalysis / Mitochondria / DNA repair / Multidisciplinary / Macromolecular X-Ray Crystallography / DNA / Humans / Protein Secondary Structure Prediction / Protein Conformation / Amino Acid Sequence / Recombinant Proteins / Nucleic Acid Conformation / Uracil Dna Glycosylase / DNA / Humans / Protein Secondary Structure Prediction / Protein Conformation / Amino Acid Sequence / Recombinant Proteins / Nucleic Acid Conformation / Uracil Dna Glycosylase
Novel dimeric interface and electrostatic recognition in bacterial Cu,Zn superoxide dismutase
Protein Folding / Multidisciplinary / Macromolecular X-Ray Crystallography / Amyotrophic Lateral Sclerosis / Free Radical / Humans / Differential scanning calorimetry / Escherichia coli / Animals / Fishes / Superoxide Dismutase / Enzyme / Cattle / Antioxidant enzyme / Molecular cloning / Active site / Protein Secondary Structure Prediction / Neurodegenerative Disease / Amino Acid Sequence / Recombinant Proteins / Dimerization / Disulfide bond / Photobacterium / Humans / Differential scanning calorimetry / Escherichia coli / Animals / Fishes / Superoxide Dismutase / Enzyme / Cattle / Antioxidant enzyme / Molecular cloning / Active site / Protein Secondary Structure Prediction / Neurodegenerative Disease / Amino Acid Sequence / Recombinant Proteins / Dimerization / Disulfide bond / Photobacterium
Aggregation propensities of superoxide dismutase G93 hotspot mutants mirror ALS clinical phenotypes
Small angle X-ray and neutron scattering / Multidisciplinary / Macromolecular X-Ray Crystallography / Amyotrophic Lateral Sclerosis / Humans / Mutation / Copper / Superoxide Dismutase / Phenotype / Solutions / Acids / Edetic Acid / Mutation / Copper / Superoxide Dismutase / Phenotype / Solutions / Acids / Edetic Acid
Preparation and characterization of novel polyimide-silica hybrids
Engineering / Materials Engineering / Chemical Engineering / Condensed Matter Physics / Thermodynamics / Inorganic Chemistry / Organic Chemistry / Biomedical Engineering / Membrane Science / Agent Based / Powder Diffraction / Atomic Force Microscopy / Macromolecular X-Ray Crystallography / Polymer / Differential scanning calorimetry / Reaction Time / Benzodiazepines / Contact angle / Laminar Flow / Phase Change / Solubility / Phase Change Material / Thermogravimetry / polymer science and Engineering / CHEMICAL SCIENCES / Composite Structure / Thermal Analysis / Spectrum / Pressure Drop / Polyethylene Glycol / Fourier transform infrared spectroscopy / Thermal Properties / Flow Rate / Aqueous Solution / Industrial Chemistry/Chemical Engineering / Low molecular weight / Biochemistry and cell biology / Molecular Structure / Inorganic Chemistry / Organic Chemistry / Biomedical Engineering / Membrane Science / Agent Based / Powder Diffraction / Atomic Force Microscopy / Macromolecular X-Ray Crystallography / Polymer / Differential scanning calorimetry / Reaction Time / Benzodiazepines / Contact angle / Laminar Flow / Phase Change / Solubility / Phase Change Material / Thermogravimetry / polymer science and Engineering / CHEMICAL SCIENCES / Composite Structure / Thermal Analysis / Spectrum / Pressure Drop / Polyethylene Glycol / Fourier transform infrared spectroscopy / Thermal Properties / Flow Rate / Aqueous Solution / Industrial Chemistry/Chemical Engineering / Low molecular weight / Biochemistry and cell biology / Molecular Structure
Structural plasticity of Cid1 provides a basis for its distributive RNA terminal uridylyl transferase activity
Macromolecular X-Ray Crystallography / Biocatalysis / Biological Sciences / Environmental Sciences / Mutation / Nucleic Acids / Schizosaccharomyces Pombe / Rotation / Nucleic Acids / Schizosaccharomyces Pombe / Rotation
An Alternative Mechanism of Bicarbonate-mediated Peroxidation by Copper-Zinc Superoxide Dismutase: RATES ENHANCED VIA PROPOSED ENZYME-ASSOCIATED PEROXYCARBONATE INTERMEDIATE
Oxidative Stress / Biological Chemistry / Macromolecular X-Ray Crystallography / Amyotrophic Lateral Sclerosis / Biological Sciences / Humans / Mutation / Copper / Biological / Zinc / Superoxide Dismutase / Enzyme / CHEMICAL SCIENCES / Hydrogen Peroxide / Humans / Mutation / Copper / Biological / Zinc / Superoxide Dismutase / Enzyme / CHEMICAL SCIENCES / Hydrogen Peroxide
Pharmacological Characterization, Structural Studies, and In Vivo Activities of Anti-Chagas Disease Lead Compounds Derived from Tipifarnib
Microbiology / Medical Microbiology / Macromolecular X-Ray Crystallography / Humans / Mice / Female / Animals / Quinolones / Chagas disease / Trypanosoma Cruzi / Trypanocidal Agents / Triazoles / Structure activity Relationship / Female / Animals / Quinolones / Chagas disease / Trypanosoma Cruzi / Trypanocidal Agents / Triazoles / Structure activity Relationship
Ansa-Cycloheptatrienyl-Cyclopentadienyl Complexes
Titanium / Silicon / Magnetic Resonance Spectroscopy / Macromolecular X-Ray Crystallography / CHEMICAL SCIENCES / Organometallic Compounds / Ligands / Molecular Structure / Organometallic Compounds / Ligands / Molecular Structure
Cytotoxic Prenylxanthones from Garcinia bracteata
Natural Products / Mass Spectrometry / Enzyme Inhibitors / Medicinal Plants / Magnetic Resonance Spectroscopy / Macromolecular X-Ray Crystallography / Biological Sciences / Humans / CHEMICAL SCIENCES / Natural / KB cells / Plant Leaves / Macromolecular X-Ray Crystallography / Biological Sciences / Humans / CHEMICAL SCIENCES / Natural / KB cells / Plant Leaves
Bunyaviridae RNA Polymerases (L-Protein) Have an N-Terminal, Influenza-Like Endonuclease Domain, Essential for Viral Cap-Dependent Transcription
Microbiology / Immunology / Medical Microbiology / Crystallization / RNA polymerase / Macromolecular X-Ray Crystallography / Influenza virus / Protein Structure and Function / Crystal structure / Humans / Sequence alignment / Human Animation / Spectrum / Active site / Bunyaviridae / Plant Pathogen / Amino Acid Sequence / RNA Dependent RNA Polymerase / Full Length Movies / Functional Equivalence / Macromolecular X-Ray Crystallography / Influenza virus / Protein Structure and Function / Crystal structure / Humans / Sequence alignment / Human Animation / Spectrum / Active site / Bunyaviridae / Plant Pathogen / Amino Acid Sequence / RNA Dependent RNA Polymerase / Full Length Movies / Functional Equivalence
Supramolecular Stabilization of a Tris(imidazolyl) Zn−Aqua Complex Evidenced by X-ray Analysis: A Structural Model for Mono-Zinc Active Sites of Enzymes
Water / Macromolecular X-Ray Crystallography / Enzymes / X Rays / Zinc / Enzyme / Metalloproteins / CHEMICAL SCIENCES / Hydrogen Bonding / Active site / Molecular Mimicry / Imidazoles / Organometallic Compounds / Structural model / Molecular Structure / Calixarenes / The American / Enzyme / Metalloproteins / CHEMICAL SCIENCES / Hydrogen Bonding / Active site / Molecular Mimicry / Imidazoles / Organometallic Compounds / Structural model / Molecular Structure / Calixarenes / The American
N,N-dimethylbiguanide complexes displaying low cytotoxicity as potential large spectrum antimicrobial agents
Organic Chemistry / Electrochemistry / Fungi / Cyclic Voltammetry / Macromolecular X-Ray Crystallography / X Rays / Humans / Metformin / Antimicrobial activity / Bacteria / Staphylococcus aureus / Pseudomonas aeruginosa / European / Spectrum / Single Crystal / HeLa cells / Spectrum analysis / Pseudomonas Aeruginosa / Organometallic Compounds / Oxidation-Reduction / X Rays / Humans / Metformin / Antimicrobial activity / Bacteria / Staphylococcus aureus / Pseudomonas aeruginosa / European / Spectrum / Single Crystal / HeLa cells / Spectrum analysis / Pseudomonas Aeruginosa / Organometallic Compounds / Oxidation-Reduction
N,N-dimethylbiguanide complexes displaying low cytotoxicity as potential large spectrum antimicrobial agents
Organic Chemistry / Electrochemistry / Fungi / Cyclic Voltammetry / Macromolecular X-Ray Crystallography / X Rays / Humans / Metformin / Antimicrobial activity / Bacteria / Staphylococcus aureus / Pseudomonas aeruginosa / European / Spectrum / Single Crystal / HeLa cells / Spectrum analysis / Pseudomonas Aeruginosa / Organometallic Compounds / Oxidation-Reduction / X Rays / Humans / Metformin / Antimicrobial activity / Bacteria / Staphylococcus aureus / Pseudomonas aeruginosa / European / Spectrum / Single Crystal / HeLa cells / Spectrum analysis / Pseudomonas Aeruginosa / Organometallic Compounds / Oxidation-Reduction
Response to Copper Stress in Streptomyces lividans Extends beyond Genes under Direct Control of a Copper-sensitive Operon Repressor Protein (CsoR)
Biological Chemistry / Macromolecular X-Ray Crystallography / Biological Sciences / Copper / CHEMICAL SCIENCES / Physiological Stress Markers
A Stable Tetraalkyl Complex of Nickel(IV)
Macromolecular X-Ray Crystallography / Nickel / CHEMICAL SCIENCES / Cyclization / Molecular Conformation / Organometallic Compounds / Ligands / Organometallic Compounds / Ligands
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