Macromolecular X-Ray Crystallography

Novel amino-β-lactam derivatives as potent cholesterol absorption inhibitors

Organic Chemistry / Macromolecular X-Ray Crystallography / Dogs / Humans / Mice / Cholesterol / Animals / Beta Lactams / Molecular Structure / Cholesterol / Animals / Beta Lactams / Molecular Structure

Protein Sequences Yield a Proteomic Code

Caenorhabditis elegans / Protein Folding / Proteomics / Polymers / Macromolecular X-Ray Crystallography / Escherichia coli / Animals / Peptides / Protein structure / Proteins / Spatial Interaction / Protein Sequence Analysis / Spectrum / Protein Conformation / Amino Acid Sequence / Proteome / Biochemistry and cell biology / Escherichia coli / Animals / Peptides / Protein structure / Proteins / Spatial Interaction / Protein Sequence Analysis / Spectrum / Protein Conformation / Amino Acid Sequence / Proteome / Biochemistry and cell biology

Novel Cytotoxic Diterpenes from Casearia arborea

Natural Products / Medicinal Plants / Magnetic Resonance Spectroscopy / Macromolecular X-Ray Crystallography / Biological Sciences / Humans / High Pressure Liquid Chromatography / CHEMICAL SCIENCES / Diterpenes / Natural / Humans / High Pressure Liquid Chromatography / CHEMICAL SCIENCES / Diterpenes / Natural

Antiparasitic activities of novel ruthenium/lapachol complexes

Inorganic Chemistry / Leishmania / Macromolecular X-Ray Crystallography / Humans / Mice / Animals / Naphthoquinones / Plasmodium falciparum / Antimalarials / Molecular Conformation / Trypanocidal Agents / Inorganic Biochemistry / Animals / Naphthoquinones / Plasmodium falciparum / Antimalarials / Molecular Conformation / Trypanocidal Agents / Inorganic Biochemistry

Antiparasitic activities of novel ruthenium/lapachol complexes

Inorganic Chemistry / Leishmania / Macromolecular X-Ray Crystallography / Humans / Mice / Animals / Naphthoquinones / Plasmodium falciparum / Antimalarials / Molecular Conformation / Trypanocidal Agents / Inorganic Biochemistry / Animals / Naphthoquinones / Plasmodium falciparum / Antimalarials / Molecular Conformation / Trypanocidal Agents / Inorganic Biochemistry

An Alternative Mechanism of Bicarbonate-mediated Peroxidation by Copper-Zinc Superoxide Dismutase: RATES ENHANCED VIA PROPOSED ENZYME-ASSOCIATED PEROXYCARBONATE INTERMEDIATE

Oxidative Stress / Biological Chemistry / Macromolecular X-Ray Crystallography / Amyotrophic Lateral Sclerosis / Biological Sciences / Humans / Mutation / Copper / Biological / Zinc / Superoxide Dismutase / Enzyme / CHEMICAL SCIENCES / Hydrogen Peroxide / Humans / Mutation / Copper / Biological / Zinc / Superoxide Dismutase / Enzyme / CHEMICAL SCIENCES / Hydrogen Peroxide

A Common Single Nucleotide Polymorphism in Endoplasmic Reticulum Aminopeptidase 2 Induces a Specificity Switch That Leads to Altered Antigen Processing

Immunology / Immunology of the Gut / Macromolecular X-Ray Crystallography / Humans / Endoplasmic Reticulum / Antigen Presentation / HeLa cells / Substrate Specificity / Genetic variation / Amino Acid Sequence / Antigen Presentation / HeLa cells / Substrate Specificity / Genetic variation / Amino Acid Sequence

Statistical measures on residue-level protein structural properties

Algorithms / Data Mining / Statistical Analysis / Structural Bioinformatics / Macromolecular X-Ray Crystallography / Biological Sciences / Environmental Sciences / Computer Simulation / Protein structure / Proteins / Structure Analysis / Amino Acids / Statistical Potential / Protein Secondary Structure Prediction / Structural Properties / Experimental Data / Statistical Estimation / Structure Determination / Software Package / Biological Sciences / Environmental Sciences / Computer Simulation / Protein structure / Proteins / Structure Analysis / Amino Acids / Statistical Potential / Protein Secondary Structure Prediction / Structural Properties / Experimental Data / Statistical Estimation / Structure Determination / Software Package

A Mitochondria-Targeted Macrocyclic Mn(II) Superoxide Dismutase Mimetic

Organic Chemistry / Catalysis / Kinetics / Mitochondria / Manganese / Macromolecular X-Ray Crystallography / Animals / Superoxide Dismutase / Ascorbic Acid / Rats / Biomimetic materials / Molecular Conformation / Chemistry Biology / Organometallic Compounds / Oxidation-Reduction / Pulse Radiolysis / Superoxides / Biochemistry and cell biology / Macromolecular X-Ray Crystallography / Animals / Superoxide Dismutase / Ascorbic Acid / Rats / Biomimetic materials / Molecular Conformation / Chemistry Biology / Organometallic Compounds / Oxidation-Reduction / Pulse Radiolysis / Superoxides / Biochemistry and cell biology

Fluoroquinolone–metal complexes: A route to counteract bacterial resistance?

Inorganic Chemistry / Macromolecular X-Ray Crystallography / Copper / Escherichia coli / Microbial Sensitivity Tests / Inorganic Biochemistry / Fluoroquinolones / Inorganic Biochemistry / Fluoroquinolones

Preliminary pharmaceutical development of antimalarial-antibiotic cotherapy as a pre-referral paediatric treatment of fever in malaria endemic areas

Malaria / Pharmaceutical Technology / Powder Diffraction / Crystallization / Pharmaceutical Chemistry / Macromolecular X-Ray Crystallography / Pharmaceutics / Humans / Animals / Endemic Diseases / Solubility / Anti-Bacterial Agents / Antimalarials / Tablets / Age Factors / Rabbits / Azithromycin / Capsules / Excipients / Biological Availability / Macromolecular X-Ray Crystallography / Pharmaceutics / Humans / Animals / Endemic Diseases / Solubility / Anti-Bacterial Agents / Antimalarials / Tablets / Age Factors / Rabbits / Azithromycin / Capsules / Excipients / Biological Availability

5-Benzylidene 1,2-Dihydrochromeno[3,4- f ]quinolines, A Novel Class of Nonsteroidal Human Progesterone Receptor Agonists

Organic Chemistry / Medicinal Chemistry / Macromolecular X-Ray Crystallography / Progesterone / Humans / Female / Animals / Rats / Medicinal / Quinolines / Structure activity Relationship / Uterus / Ovariectomy / Female / Animals / Rats / Medicinal / Quinolines / Structure activity Relationship / Uterus / Ovariectomy

Copper (II) Complexes of [1,2,4]Triazolo [1,5-a]Pyrimidine Derivatives as Potential Anti-Parasitic Agents

Drug metabolism / Macrophages / Leishmania / Magnetic Resonance Spectroscopy / Macromolecular X-Ray Crystallography / Energy Metabolism / Cercopithecus aethiops / Copper / Mice / Animals / Drug Design / Trypanosoma Cruzi / Triazoles / NAD / Organometallic Compounds / Vero cells / Energy Metabolism / Cercopithecus aethiops / Copper / Mice / Animals / Drug Design / Trypanosoma Cruzi / Triazoles / NAD / Organometallic Compounds / Vero cells

Identification and Characterization of gamma-Glutamylamine Cyclotransferase, an Enzyme Responsible for gamma-Glutamyl-epsilon-lysine Catabolism

Catalysis / Biological Chemistry / Macromolecular X-Ray Crystallography / Biological Sciences / Humans / CHEMICAL SCIENCES / Molecular cloning / Protein Conformation / Amino Acid Sequence / CHEMICAL SCIENCES / Molecular cloning / Protein Conformation / Amino Acid Sequence

Bicyclic glutamic acid derivatives

Analytical Chemistry / Organic Chemistry / Macromolecular X-Ray Crystallography / Chirality / Circular Dichroism / Cyclization / Hydrolysis / Esters / Glutamic Acid / Hot Temperature / Molecular Structure / Solvents / Cyclization / Hydrolysis / Esters / Glutamic Acid / Hot Temperature / Molecular Structure / Solvents

An Iron Nitride Complex

Macromolecular X-Ray Crystallography / CHEMICAL SCIENCES / Electrons / Spectrum analysis / NITRIC ACID / Iron Compounds / Molecular Structure / Iron Compounds / Molecular Structure

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