In Vitro

In vivo active antimalarial isonitriles

Organic Chemistry / Treatment / Porifera / In Vitro / Nitriles / Mice / Multidrug Resistance / Animals / In Vivo / Plasmodium falciparum / Antimalarials / Microbial Sensitivity Tests / Biological activity / Plasmodium yoelii / Structure activity Relationship / Chemical Synthesis / Mice / Multidrug Resistance / Animals / In Vivo / Plasmodium falciparum / Antimalarials / Microbial Sensitivity Tests / Biological activity / Plasmodium yoelii / Structure activity Relationship / Chemical Synthesis

Dimethylarginine Dimethylaminohydrolase Regulates Nitric Oxide Synthesis: Genetic and Physiological Evidence

Genetics / Physiology / Metabolism / Cardiovascular / Control / Regulation / Cardiovascular Physiology / Transgenic Mice / In Vitro / Humans / Hemodynamics / Mice / Blood Pressure / Nitric oxide / Resistance / Animals / Cell / Plasma / Transgenic Animals / Volume / ATP synthase / Expression / Gene / Reduction / Risk factors / Vascular / Support / Enzyme / Clinical Sciences / Cultured meat / In Vivo / Activity / Nitric Oxide Synthase / Endothelial cell / Public health systems and services research / Endogenous / Circulation / Arginine / Risk Factors / Transfection / Transgenic / ENDOTHELIUM / Serum Asymmetric Dimethylarginine (ADMA) / Vasodilation / Level / Urinary / Gene Transfer / Systolic blood pressure / Vascular Resistance / Mm / Contractility / Regulation / Cardiovascular Physiology / Transgenic Mice / In Vitro / Humans / Hemodynamics / Mice / Blood Pressure / Nitric oxide / Resistance / Animals / Cell / Plasma / Transgenic Animals / Volume / ATP synthase / Expression / Gene / Reduction / Risk factors / Vascular / Support / Enzyme / Clinical Sciences / Cultured meat / In Vivo / Activity / Nitric Oxide Synthase / Endothelial cell / Public health systems and services research / Endogenous / Circulation / Arginine / Risk Factors / Transfection / Transgenic / ENDOTHELIUM / Serum Asymmetric Dimethylarginine (ADMA) / Vasodilation / Level / Urinary / Gene Transfer / Systolic blood pressure / Vascular Resistance / Mm / Contractility

Dimethylarginine Dimethylaminohydrolase Regulates Nitric Oxide Synthesis Genetic and Physiological Evidence

Genetics / Physiology / Metabolism / Cardiovascular / Control / Regulation / Cardiovascular Physiology / Transgenic Mice / In Vitro / Humans / Hemodynamics / Mice / Blood Pressure / Nitric oxide / Resistance / Animals / Cell / Plasma / Transgenic Animals / Volume / ATP synthase / Expression / Gene / Reduction / Risk factors / Vascular / Support / Enzyme / Clinical Sciences / Cultured meat / In Vivo / Activity / Nitric Oxide Synthase / Endothelial cell / Public health systems and services research / Endogenous / Circulation / Arginine / Risk Factors / Transfection / Transgenic / ENDOTHELIUM / Serum Asymmetric Dimethylarginine (ADMA) / Vasodilation / Level / Urinary / Gene Transfer / Systolic blood pressure / Vascular Resistance / Mm / Contractility / Regulation / Cardiovascular Physiology / Transgenic Mice / In Vitro / Humans / Hemodynamics / Mice / Blood Pressure / Nitric oxide / Resistance / Animals / Cell / Plasma / Transgenic Animals / Volume / ATP synthase / Expression / Gene / Reduction / Risk factors / Vascular / Support / Enzyme / Clinical Sciences / Cultured meat / In Vivo / Activity / Nitric Oxide Synthase / Endothelial cell / Public health systems and services research / Endogenous / Circulation / Arginine / Risk Factors / Transfection / Transgenic / ENDOTHELIUM / Serum Asymmetric Dimethylarginine (ADMA) / Vasodilation / Level / Urinary / Gene Transfer / Systolic blood pressure / Vascular Resistance / Mm / Contractility

Phospholipid Metabolism in Neural Microvascular Endothelial Cells after Exposure to Lead in Vitro

Phospholipids / Calcium / In Vitro / Brain / Toxicity / Capillaries / Permeability / Animals / Lead / Vascular endothelium / Terpenes / Marine Toxins / Cattle / Endothelial cell / Imidazoles / Amino Acid Sequence / Arachidonic Acid / Molecular Sequence Data / Inositol Phosphates / Capillaries / Permeability / Animals / Lead / Vascular endothelium / Terpenes / Marine Toxins / Cattle / Endothelial cell / Imidazoles / Amino Acid Sequence / Arachidonic Acid / Molecular Sequence Data / Inositol Phosphates

Indanylacetic acids as PPAR-δ activator insulin sensitizers

Organic Chemistry / Fluorescence Resonance Energy Transfer / Nuclear Receptor / Insulin Resistance / In Vitro / Insulin / In Vivo / Spectrum / PPAR / Acetic Acid / Bioorganic and medicinal Chemistry / Structure activity Relationship / Ligand / Chemical Synthesis / Selectivity / Activator / Insulin / In Vivo / Spectrum / PPAR / Acetic Acid / Bioorganic and medicinal Chemistry / Structure activity Relationship / Ligand / Chemical Synthesis / Selectivity / Activator

Indanylacetic acids as PPAR-δ activator insulin sensitizers

Organic Chemistry / Fluorescence Resonance Energy Transfer / Nuclear Receptor / Insulin Resistance / In Vitro / Insulin / In Vivo / Spectrum / PPAR / Acetic Acid / Bioorganic and medicinal Chemistry / Structure activity Relationship / Ligand / Chemical Synthesis / Selectivity / Activator / Insulin / In Vivo / Spectrum / PPAR / Acetic Acid / Bioorganic and medicinal Chemistry / Structure activity Relationship / Ligand / Chemical Synthesis / Selectivity / Activator

In vitro and in vivo comparison of two non-peptide tachykinin NK3 receptor antagonists: Improvements in efficacy achieved through enhanced brain penetration or altered pharmacological characteristics

Animal Behavior / Neurotransmission / Pharmacokinetics / Comparative Study / Prefrontal Cortex / Nucleus Accumbens / Dopamine / In Vitro / Brain / Humans / Cerebral Cortex / Animals / Male / Central Nervous System / Peptides / Habenula / Neurons / Efficiency / Haloperidol / European / Microdialysis / Molecular cloning / In Vivo / Rats / Neuronal Activity / Guinea Pig / Substance P / Quinolines / Extracellular Space / Pharmacokinetic / Medial Prefrontal Cortex / Clinical evaluation / Inositol Phosphates / Nucleus Accumbens / Dopamine / In Vitro / Brain / Humans / Cerebral Cortex / Animals / Male / Central Nervous System / Peptides / Habenula / Neurons / Efficiency / Haloperidol / European / Microdialysis / Molecular cloning / In Vivo / Rats / Neuronal Activity / Guinea Pig / Substance P / Quinolines / Extracellular Space / Pharmacokinetic / Medial Prefrontal Cortex / Clinical evaluation / Inositol Phosphates

Transformation of Cinchona Alkaloids into 1-N-Oxide Derivatives by Endophytic Xylaria sp. Isolated from Cinchona pubescens

Chemical / Fungi / In Vitro / Biotransformation / Oxidation / Oxides / Cinchona / Thallophyta / Oxides / Cinchona / Thallophyta

A semiparametric deconvolution model to establish in vivo-in vitro correlation applied to OROS oxybutynin

Modeling / Prediction / Pharmacokinetics / Pharmaceutical Chemistry / Dosage Form / In Vitro / Humans / Controlled release / Pharmaceutical Sciences / Estimation / Bioavailability / Mathematical Model / In Vivo / Linear Systems / Reproducibility of Results / Active Ingredient / Biological Availability / Enantiomer / Statistics as Topic / In Vitro / Humans / Controlled release / Pharmaceutical Sciences / Estimation / Bioavailability / Mathematical Model / In Vivo / Linear Systems / Reproducibility of Results / Active Ingredient / Biological Availability / Enantiomer / Statistics as Topic

Antioxidant activities of different tissue extract of faba bean (Vicia faba L.) containing phenolic compounds

Free Radicals / In Vitro / Polyphenols / Legume

Efecto del Ácido Giberélico dobre el Crecimiento de Explantes de Papa (Solanum Tuberosum L.)

In Vitro / regulador de crecimiento / yemas vegetativas

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