Transformation of Cinchona Alkaloids into 1-N-Oxide Derivatives by Endophytic Xylaria sp. Isolated from Cinchona pubescens

2003 Alkaloids U 0600

24- 181

Alkaloids

Transformation of Cinchona Alkaloids into 1-N-Oxide Derivatives by Endophytic Xylaria sp. Isolated from Cinchona pubescens. — Quinidine and cinchonine are also transformed to the corresponding N-oxides. — (SHIBUYA*, H.; KITAMURA, C.; MAEHARA, S.; NAGAHATA, M.; WINARNO, H.; SIMANJUNTAK, P.; KIM, H.-S.; WATAYA, Y.; OHASHI, K.; Chem. Pharm. Bull. 51 (2003) 1, 71-74; Fac. Pharm. Pharm. Sci., Fukuyama Univ., Fukuyama, Hiroshima 729-02, Japan; Eng.) — K. Schneider