In Vitro

Carbamoyloximes as novel non-competitive mGlu5 receptor antagonists

Organic Chemistry / In Vitro / Animals / Metabotropic Glutamate Receptors / Enzyme / Rats / Oximes / Substrate Specificity / Pyridines / Bioorganic and medicinal Chemistry / Affinity / Chemical Synthesis / Carbamates / Rats / Oximes / Substrate Specificity / Pyridines / Bioorganic and medicinal Chemistry / Affinity / Chemical Synthesis / Carbamates

Intracerebral microdialysis: I. Experimental studies of diffusion kinetics

Kinetics / Dialysis / Concentration / In Vitro / Diffusion / Animals / Method / Male / Temperature / Perfusion / Difusion / Experimental Study / High Pressure Liquid Chromatography / Microdialysis / In Vivo / Rats / Rat / Pharmacological / Brain Chemistry / Pharmacological Methods / Extracellular Space / Animals / Method / Male / Temperature / Perfusion / Difusion / Experimental Study / High Pressure Liquid Chromatography / Microdialysis / In Vivo / Rats / Rat / Pharmacological / Brain Chemistry / Pharmacological Methods / Extracellular Space

Novel 3-N-Aminoglycoside Acetyltransferase Gene, aac(3)Ic, from a Pseudomonas aeruginosa Integron

Microbiology / Medical Microbiology / In Vitro / Humans / Escherichia coli / Resistance / Bacteria / Gene / Pseudomonas aeruginosa / Molecular cloning / Integrons / Gen / Genotype / Pseudomonas Aeruginosa / Biological activity / Amino Acid Sequence / Beta Lactamases / Resistance / Bacteria / Gene / Pseudomonas aeruginosa / Molecular cloning / Integrons / Gen / Genotype / Pseudomonas Aeruginosa / Biological activity / Amino Acid Sequence / Beta Lactamases

Horseradish peroxidase transport across rat alveolar epithelial cell monolayers

Peroxidase / In Vitro / Tissue culture / Endocytosis / Pharmaceutical / Membrane transport / Mechanism / Proteins / Peroxidases / Rat / Membrane transport / Mechanism / Proteins / Peroxidases / Rat

Antimicrobial activity of Terminalia macroptera root

Complementary and Alternative Medicine / Plant Biology / Ethnopharmacology / Pharmacognosy / Medicinal Plants / In Vitro / ROOT / Infectious Disease / Escherichia coli / Vibrio cholerae / Antimicrobial activity / Bacteria / Ethanol / Candida albicans / Enterobacteriaceae / Plant Roots / Guinea Bissau / Anti-Bacterial Agents / Plant extracts / Microbial Sensitivity Tests / Biological activity / Extract / Medicinal Plant / Minimum inhibitory concentration / Thallophyta / In Vitro / ROOT / Infectious Disease / Escherichia coli / Vibrio cholerae / Antimicrobial activity / Bacteria / Ethanol / Candida albicans / Enterobacteriaceae / Plant Roots / Guinea Bissau / Anti-Bacterial Agents / Plant extracts / Microbial Sensitivity Tests / Biological activity / Extract / Medicinal Plant / Minimum inhibitory concentration / Thallophyta

2-Arylpyrimidines: Novel CRF-1 receptor antagonists

Organic Chemistry / Depression / Kinetics / Pharmacokinetics / Pharmaceutical Chemistry / In Vitro / Humans / Animals / Drug Design / Solubility / In Vivo / Rats / Rat / Ether / Molecular Conformation / Bioorganic and medicinal Chemistry / Affinity / Structure activity Relationship / Chemical Synthesis / Molecular Structure / In Vitro / Humans / Animals / Drug Design / Solubility / In Vivo / Rats / Rat / Ether / Molecular Conformation / Bioorganic and medicinal Chemistry / Affinity / Structure activity Relationship / Chemical Synthesis / Molecular Structure

PPARgamma regulates adipose triglyceride lipase in adipocytes in vitro and in vivo

Calcium / Membrane Proteins / Gene expression / Biological Sciences / In Vitro / Mice / Animals / Leptin / Brown Adipose Tissue / In Vivo / Adipocytes / Lipase / Protein Biosynthesis / Cycloheximide / Mice / Animals / Leptin / Brown Adipose Tissue / In Vivo / Adipocytes / Lipase / Protein Biosynthesis / Cycloheximide

Phase transfer catalyzed synthesis of bis-quinolines: Antileishmanial activity in experimental visceral leishmaniasis and in vitro antibacterial evaluation

Organic Chemistry / Catalysis / Treatment / Transmission Electron Microscopy / In Vitro / Mice / Animals / Visceral Leishmaniasis / Methane / European / Antibacterial activity / In Vivo / Anti-Bacterial Agents / Microbial Sensitivity Tests / Quinolines / Structure activity Relationship / Chemical Synthesis / Mice / Animals / Visceral Leishmaniasis / Methane / European / Antibacterial activity / In Vivo / Anti-Bacterial Agents / Microbial Sensitivity Tests / Quinolines / Structure activity Relationship / Chemical Synthesis

In Vitro and in Vivo Killing of Acute Lymphoblastic Leukemia Cells by L-Asparaginase1

Cancer / Flow Cytometry / Prediction / Treatment / Cytotoxicity / Cell Culture / In Vitro / Bone marrow / Enzyme / In Vivo / Biological activity / Cell Surface Markers / Propidium Iodide / Acute Lymphoblastic Leukemia / Cell Culture / In Vitro / Bone marrow / Enzyme / In Vivo / Biological activity / Cell Surface Markers / Propidium Iodide / Acute Lymphoblastic Leukemia

New vasorelaxant indole alkaloids, villocarines A–D from Uncaria villosa

Organic Chemistry / Calcium / Pharmacognosy / Magnetic Resonance Spectroscopy / Structural Analysis / In Vitro / Endothelial Cells / Nitric oxide / Animals / Calcium channels / Potassium / Isolation / Rats / Endothelial cell / Rat / Voltage-Gated Potassium Channels / Molecular Conformation / Bioorganic and medicinal Chemistry / Biological activity / Uncaria / Aorta / Indole Alkaloids / Plant Leaves / In Vitro / Endothelial Cells / Nitric oxide / Animals / Calcium channels / Potassium / Isolation / Rats / Endothelial cell / Rat / Voltage-Gated Potassium Channels / Molecular Conformation / Bioorganic and medicinal Chemistry / Biological activity / Uncaria / Aorta / Indole Alkaloids / Plant Leaves

In Vitro and in Vivo Killing of Acute Lymphoblastic Leukemia Cells by L-Asparaginase1

Cancer / Flow Cytometry / Prediction / Treatment / Cytotoxicity / Cell Culture / In Vitro / Bone marrow / Enzyme / In Vivo / Biological activity / Cell Surface Markers / Propidium Iodide / Acute Lymphoblastic Leukemia / Cell Culture / In Vitro / Bone marrow / Enzyme / In Vivo / Biological activity / Cell Surface Markers / Propidium Iodide / Acute Lymphoblastic Leukemia

A peptide sequence on carcinoembryonic antigen binds to a 80kD protein on kupffer cells

In Vitro / Endocytosis / Biochemical / Clearance / Rat / Biochemistry and cell biology

A semiparametric deconvolution model to establish in vivo-in vitro correlation applied to OROS oxybutynin

Modeling / Prediction / Pharmacokinetics / Pharmaceutical Chemistry / Dosage Form / In Vitro / Humans / Controlled release / Pharmaceutical Sciences / Estimation / Bioavailability / Mathematical Model / In Vivo / Linear Systems / Reproducibility of Results / Active Ingredient / Biological Availability / Enantiomer / In Vitro / Humans / Controlled release / Pharmaceutical Sciences / Estimation / Bioavailability / Mathematical Model / In Vivo / Linear Systems / Reproducibility of Results / Active Ingredient / Biological Availability / Enantiomer
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