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Down-Regulation
Down-Regulation
Apoptotic mimicry by an obligate intracellular parasite downregulates macrophage microbicidal activity
Macrophages / Leishmania / Apoptosis / Biological Sciences / Animals / Programmed cell death / Transforming Growth Factor Beta / Hydra / Down-Regulation / Transforming Growth Factor / Programmed cell death / Transforming Growth Factor Beta / Hydra / Down-Regulation / Transforming Growth Factor
Identification of amino acid residues critical for endonuclease and integration activities of HIV-1 IN protein in Vitro
Bacteriology / Catalysis / Flow Cytometry / Virology / Calcium / Biological Chemistry / Magnetic Resonance Spectroscopy / Gene expression / Cell separation / Biocatalysis / Signal Transduction / HIV / Biological Sciences / Cell line / Identification / Humans / Mutagenesis / Sequence alignment / Mutation / Placenta / Virus / Escherichia coli / Animals / Plants / Monoclonal Antibodies / Chemotaxis / Phosphorylation / Plasmids / Affinity chromatography / Phenotype / Phosphotyrosine / CHEMICAL SCIENCES / Molecular cloning / Amino Acids / Mycoplasma Genitalium / Lysine / Amino Acid Profile / Transfection / Protein Conformation / Amino Acid Sequence / Base Sequence / Amino Acid Substitution Rates / Chemokines / Structure activity Relationship / Newcastle Disease Virus / Recombinant Proteins / Protein Binding / Hydrolysis / DNA binding proteins / Site-directed Mutagenesis / Interleukin / Interferon Alpha / Down-Regulation / Molecular Sequence Data / Biological Chemistry / Magnetic Resonance Spectroscopy / Gene expression / Cell separation / Biocatalysis / Signal Transduction / HIV / Biological Sciences / Cell line / Identification / Humans / Mutagenesis / Sequence alignment / Mutation / Placenta / Virus / Escherichia coli / Animals / Plants / Monoclonal Antibodies / Chemotaxis / Phosphorylation / Plasmids / Affinity chromatography / Phenotype / Phosphotyrosine / CHEMICAL SCIENCES / Molecular cloning / Amino Acids / Mycoplasma Genitalium / Lysine / Amino Acid Profile / Transfection / Protein Conformation / Amino Acid Sequence / Base Sequence / Amino Acid Substitution Rates / Chemokines / Structure activity Relationship / Newcastle Disease Virus / Recombinant Proteins / Protein Binding / Hydrolysis / DNA binding proteins / Site-directed Mutagenesis / Interleukin / Interferon Alpha / Down-Regulation / Molecular Sequence Data
Identification of amino acid residues critical for endonuclease and integration activities of HIV1 IN protein in Vitro
Bacteriology / Catalysis / Flow Cytometry / Virology / Calcium / Biological Chemistry / Magnetic Resonance Spectroscopy / Gene expression / Cell separation / Biocatalysis / Signal Transduction / HIV / Biological Sciences / Cell line / Identification / Humans / Mutagenesis / Sequence alignment / Mutation / Placenta / Virus / Escherichia coli / Animals / Biological / Plants / Monoclonal Antibodies / Chemotaxis / Phosphorylation / Plasmids / Affinity chromatography / Phenotype / Phosphotyrosine / CHEMICAL SCIENCES / Molecular cloning / Amino Acids / Mycoplasma Genitalium / Lysine / Amino Acid Profile / Transfection / Protein Conformation / Amino Acid Sequence / Base Sequence / Amino Acid Substitution Rates / Chemokines / Structure activity Relationship / Newcastle Disease Virus / Recombinant Proteins / Protein Binding / Hydrolysis / DNA binding proteins / Site-directed Mutagenesis / Interleukin / Interferon Alpha / Down-Regulation / Molecular Sequence Data / Biological Chemistry / Magnetic Resonance Spectroscopy / Gene expression / Cell separation / Biocatalysis / Signal Transduction / HIV / Biological Sciences / Cell line / Identification / Humans / Mutagenesis / Sequence alignment / Mutation / Placenta / Virus / Escherichia coli / Animals / Biological / Plants / Monoclonal Antibodies / Chemotaxis / Phosphorylation / Plasmids / Affinity chromatography / Phenotype / Phosphotyrosine / CHEMICAL SCIENCES / Molecular cloning / Amino Acids / Mycoplasma Genitalium / Lysine / Amino Acid Profile / Transfection / Protein Conformation / Amino Acid Sequence / Base Sequence / Amino Acid Substitution Rates / Chemokines / Structure activity Relationship / Newcastle Disease Virus / Recombinant Proteins / Protein Binding / Hydrolysis / DNA binding proteins / Site-directed Mutagenesis / Interleukin / Interferon Alpha / Down-Regulation / Molecular Sequence Data
Epilobium angustifolium extract demonstrates multiple effects on dermal fibroblasts in vitro and skin photo-protection in vivo
Physiology / Adolescent / Extracellular Matrix / Humans / Child / Young Adult / Skin / Medical Physiology / Phenotype / Plant extracts / Epilobium / Adult / Skin Aging / Cell Survival / Sirtuin / Gene Expression Regulation / Cell Adhesion Molecules / Down-Regulation / Young Adult / Skin / Medical Physiology / Phenotype / Plant extracts / Epilobium / Adult / Skin Aging / Cell Survival / Sirtuin / Gene Expression Regulation / Cell Adhesion Molecules / Down-Regulation
MicroRNA-132 Potentiates Cholinergic Anti-Inflammatory Signaling by Targeting Acetylcholinesterase
Immunology / MicroRNA / Inflammation / Macrophages / Signal Transduction / Cell line / Humans / Mice / Immunity / Female / Animals / Acetylcholinesterase / Acetylcholine / microRNAs / Lipopolysaccharides / Base Sequence / Oligonucleotides / Bone Marrow Cells / Down-Regulation / Molecular Sequence Data / Cell line / Humans / Mice / Immunity / Female / Animals / Acetylcholinesterase / Acetylcholine / microRNAs / Lipopolysaccharides / Base Sequence / Oligonucleotides / Bone Marrow Cells / Down-Regulation / Molecular Sequence Data
Intracellular expression of antisense RNA transcripts complementary to the human immunodeficiency virus type-1 vif gene inhibits viral replication in infected T-lymphoblastoid cells
Gene Therapy / HIV / Cell line / Humans / Biochemical / T lymphocytes / Human immunodeficiency virus / Amino Acid Profile / Base Sequence / Antisense RNA / Biochemistry and cell biology / Nucleic Acid / Down-Regulation / T lymphocytes / Human immunodeficiency virus / Amino Acid Profile / Base Sequence / Antisense RNA / Biochemistry and cell biology / Nucleic Acid / Down-Regulation
Intracellular expression of antisense RNA transcripts complementary to the human immunodeficiency virus type-1 vif gene inhibits viral replication in infected T-lymphoblastoid cells
Gene Therapy / HIV / Cell line / Humans / Biochemical / T lymphocytes / Human immunodeficiency virus / Amino Acid Profile / Base Sequence / Antisense RNA / Biochemistry and cell biology / Nucleic Acid / Down-Regulation / T lymphocytes / Human immunodeficiency virus / Amino Acid Profile / Base Sequence / Antisense RNA / Biochemistry and cell biology / Nucleic Acid / Down-Regulation
Loss of Prion Protein in a Transgenic Model of Amyotrophic Lateral Sclerosis
Cognitive Science / Protein Folding / Skeletal muscle biology / Motor neuron / Transgenic Mice / Amyotrophic Lateral Sclerosis / Molecular chaperones / Molecular and cellular biology / Genetic Testing / Mutation / Mice / Animals / Spinal Cord / Superoxide Dismutase / Western blot / Sciatic Nerve / Cellular and Molecular Neuroscience / Enzymatic Activity / Neurosciences / Down-Regulation / Prion Protein / DNA mutational analysis / Amyotrophic Lateral Sclerosis / Molecular chaperones / Molecular and cellular biology / Genetic Testing / Mutation / Mice / Animals / Spinal Cord / Superoxide Dismutase / Western blot / Sciatic Nerve / Cellular and Molecular Neuroscience / Enzymatic Activity / Neurosciences / Down-Regulation / Prion Protein / DNA mutational analysis
Tapasin decreases immune responsiveness to a model tumor antigen
Immunology / Immune response / Pancreatic Cancer / Molecular chaperones / Clinical immunology / Humans / Clinical / Mucin / Antigen Presentation / Glycoproteins / Membrane transport proteins / Major histocompatibility complex / Transfection / Cell Surface Markers / Mucins / Antigens / Immunoglobulins / MHC class I / Down-Regulation / Humans / Clinical / Mucin / Antigen Presentation / Glycoproteins / Membrane transport proteins / Major histocompatibility complex / Transfection / Cell Surface Markers / Mucins / Antigens / Immunoglobulins / MHC class I / Down-Regulation
Apoptotic Mimicry by An Obligate Intracellular Parasite Downregulates Macrophage Microbicidal Activity
Macrophages / Leishmania / Apoptosis / Biological Sciences / Animals / Programmed cell death / Transforming Growth Factor Beta / Hydra / Down-Regulation / Transforming Growth Factor / Programmed cell death / Transforming Growth Factor Beta / Hydra / Down-Regulation / Transforming Growth Factor
Repression of glucocorticoid receptor gene transcription by c-Jun
Gene regulation / Gene expression / Signal Transduction / Biological Sciences / Molecular and cellular biology / Humans / Mice / Animals / T cells / Transcription Factor / Transfection / Glucocorticoids / Down-Regulation / Humans / Mice / Animals / T cells / Transcription Factor / Transfection / Glucocorticoids / Down-Regulation
Low expression of catecholamine-O-methyl-transferase gene in obsessive-compulsive disorder
Psychology / Anxiety Disorders / RNA / Gene expression / Anxiety / Humans / Female / Male / Gender Difference / Polymerase Chain Reaction / Obsessive Compulsive Disorder / Clinical Sciences / Adult / ANXIETY / Leukocytes / Down-Regulation / Humans / Female / Male / Gender Difference / Polymerase Chain Reaction / Obsessive Compulsive Disorder / Clinical Sciences / Adult / ANXIETY / Leukocytes / Down-Regulation
Posttranscriptional Inhibition of Interferon-Gamma Production by Lead
Innate immunity / Spleen / Cell line / Mice / Animals / Male / Lead / Time Factors / Zinc Compounds / Protein Biosynthesis / Interleukin / Down-Regulation / Interferon gamma / Chlorides / Male / Lead / Time Factors / Zinc Compounds / Protein Biosynthesis / Interleukin / Down-Regulation / Interferon gamma / Chlorides
Temporal gene expression profiling reveals CEBPD as a candidate regulator of brain disease in prosaposin deficient mice
Cognitive Science / Immunohistochemistry / Gene expression / Cerebellum / Mice / Animals / Cluster Analysis / Central Nervous System / Neurons / Transcription Factor / Spectrum / Microarray Analysis / Age Factors / Purkinje Cells / Neurosciences / Biochemistry and cell biology / Brain Diseases / Gene expression profiling / Purkinje cell / Down-Regulation / Motor activity / Animals / Cluster Analysis / Central Nervous System / Neurons / Transcription Factor / Spectrum / Microarray Analysis / Age Factors / Purkinje Cells / Neurosciences / Biochemistry and cell biology / Brain Diseases / Gene expression profiling / Purkinje cell / Down-Regulation / Motor activity
Oxidized-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine induces vascular endothelial superoxide production: implication of NADPH oxidase
Animals / Glutathione / Vascular endothelium / NADPH oxidase / Cattle / mRna expression levels / RT PCR / siRNA / Vascular Endothelial Function / SDS PAGE / Low Density Lipoprotein (LDL) / Superoxides / Biochemistry and cell biology / Matrix Metalloproteinase / Down-Regulation / Bovine Aortic Endothelial Cells / mRna expression levels / RT PCR / siRNA / Vascular Endothelial Function / SDS PAGE / Low Density Lipoprotein (LDL) / Superoxides / Biochemistry and cell biology / Matrix Metalloproteinase / Down-Regulation / Bovine Aortic Endothelial Cells
Oxidized1-palmitoyl-2-arachidonoyl- sn-glycero-3-phosphorylcholine induces vascular endothelial superoxide production: Implication of NADPH oxidase
Animals / Glutathione / Vascular endothelium / NADPH oxidase / Cattle / mRna expression levels / RT PCR / siRNA / Vascular Endothelial Function / SDS PAGE / Low Density Lipoprotein (LDL) / Superoxides / Biochemistry and cell biology / Matrix Metalloproteinase / Down-Regulation / Bovine Aortic Endothelial Cells / mRna expression levels / RT PCR / siRNA / Vascular Endothelial Function / SDS PAGE / Low Density Lipoprotein (LDL) / Superoxides / Biochemistry and cell biology / Matrix Metalloproteinase / Down-Regulation / Bovine Aortic Endothelial Cells
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