Down-Regulation - Page 6

Histone Deacetylase Inhibitors Decrease DNA Methyltransferase-3B Messenger RNA Stability and Down-regulate De novo DNA Methyltransferase Activity in Human Endometrial Cells

Molecular Biology / Cancer / Protein synthesis / Endometrial Cancer / Humans / Female / HIstone Deacetylase / DNA methylation / mRNA stability / Western blot / Protein Expression / Histone deacetylase inhibitor / Hydroxamic Acids / Histone Acetylation / Anticancer Drug / Histone deacetylase inhibitors / Down-Regulation / Female / HIstone Deacetylase / DNA methylation / mRNA stability / Western blot / Protein Expression / Histone deacetylase inhibitor / Hydroxamic Acids / Histone Acetylation / Anticancer Drug / Histone deacetylase inhibitors / Down-Regulation

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CD36 Deficiency Leads to Choroidal Involution via COX2 Down-Regulation in Rodents

Retinal Pigment Epithelium / Molecular Mechanics / Mice / Animals / Retinal Degeneration / Age related macular degeneration / Rats / Degeneration / Wistar Rats / Spontaneously Hypertensive Rat / Vascular Endothelial Growth Factor / Down-Regulation / Age related macular degeneration / Rats / Degeneration / Wistar Rats / Spontaneously Hypertensive Rat / Vascular Endothelial Growth Factor / Down-Regulation

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Hormone receptor loss in endometrial carcinoma curettage predicts lymph node metastasis and poor outcome in prospective multicentre trial

Treatment Outcome / Risk assessment / Biopsy / Prospective studies / Humans / Europe / Female / Risk factors / Aged / Middle Aged / Carcinoma / Adult / Time Factors / Odds ratio / Chi Square Distribution / Risk Factors / Risk Assessment / Proportional Hazards Models / Logistic Models / Predictive value of tests / Down-Regulation / Europe / Female / Risk factors / Aged / Middle Aged / Carcinoma / Adult / Time Factors / Odds ratio / Chi Square Distribution / Risk Factors / Risk Assessment / Proportional Hazards Models / Logistic Models / Predictive value of tests / Down-Regulation

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Human colonic intraepithelial lymphocytes suppress in vitro immunoglobulin synthesis by autologous peripheral blood lymphocytes and lamina propria lymphocytes

Adolescent / Cell Division / Humans / Female / Male / Clinical Sciences / T lymphocytes / Aged / Middle Aged / Epithelium / Adult / Gut / Colon / Immune Tolerance / Immunoglobulins / immunoglobulin G / Inflammatory Bowel Diseases / Down-Regulation / Clinical Sciences / T lymphocytes / Aged / Middle Aged / Epithelium / Adult / Gut / Colon / Immune Tolerance / Immunoglobulins / immunoglobulin G / Inflammatory Bowel Diseases / Down-Regulation

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Apoptotic mimicry by an obligate intracellular parasite downregulates macrophage microbicidal activity

Macrophages / Leishmania / Apoptosis / Biological Sciences / Animals / Programmed cell death / Transforming Growth Factor Beta / Hydra / Down-Regulation / Programmed cell death / Transforming Growth Factor Beta / Hydra / Down-Regulation

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Human Freud-2/CC2D1B: A Novel Repressor of Postsynaptic Serotonin-1A Receptor Expression

Polymorphism / Biological Sciences / Biological Psychiatry / Serotonin / Brain / Humans / Major Depressive Disorder / Male / Biological / Transcription Factor / Neuroblastoma / Middle Aged / Molecular cloning / Adult / Transfection / Protein Binding / DNA binding proteins / Down-Regulation / Humans / Major Depressive Disorder / Male / Biological / Transcription Factor / Neuroblastoma / Middle Aged / Molecular cloning / Adult / Transfection / Protein Binding / DNA binding proteins / Down-Regulation

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MicroRNA-132 Potentiates Cholinergic Anti-Inflammatory Signaling by Targeting Acetylcholinesterase

Immunology / MicroRNA / Inflammation / Macrophages / Signal Transduction / Cell line / Humans / Mice / Immunity / Female / Animals / Acetylcholinesterase / Acetylcholine / microRNAs / Lipopolysaccharides / Base Sequence / Oligonucleotides / Bone Marrow Cells / Down-Regulation / Cell line / Humans / Mice / Immunity / Female / Animals / Acetylcholinesterase / Acetylcholine / microRNAs / Lipopolysaccharides / Base Sequence / Oligonucleotides / Bone Marrow Cells / Down-Regulation

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Suppression of PC-1/ENPP-1 expression improves insulin sensitivity in vitro and in vivo

Type 2 Diabetes / Transgenic Mice / Signal Transduction / Cell line / Humans / Blood Glucose / Insulin / Fasting / Mice / Animals / Male / P-glycoprotein / Insulin signaling / Animal Model / Phosphorylation / European / Time Factors / Hepatocytes / Genetic Polymorphism / Transfection / Insulin Receptor / Tyrosine / Tyrosine Phosphorylation / Down-Regulation / Blood Glucose / Insulin / Fasting / Mice / Animals / Male / P-glycoprotein / Insulin signaling / Animal Model / Phosphorylation / European / Time Factors / Hepatocytes / Genetic Polymorphism / Transfection / Insulin Receptor / Tyrosine / Tyrosine Phosphorylation / Down-Regulation

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Suppression of PC-1/ENPP-1 expression improves insulin sensitivity in vitro and in vivo

Type 2 Diabetes / Transgenic Mice / Signal Transduction / Cell line / Humans / Blood Glucose / Insulin / Fasting / Mice / Animals / Male / P-glycoprotein / Insulin signaling / Animal Model / Phosphorylation / European / Time Factors / Hepatocytes / Genetic Polymorphism / Transfection / Insulin Receptor / Tyrosine / Tyrosine Phosphorylation / Down-Regulation / Blood Glucose / Insulin / Fasting / Mice / Animals / Male / P-glycoprotein / Insulin signaling / Animal Model / Phosphorylation / European / Time Factors / Hepatocytes / Genetic Polymorphism / Transfection / Insulin Receptor / Tyrosine / Tyrosine Phosphorylation / Down-Regulation

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Large intra- and inter-individual variability of genes expression levels limits potential predictive value of molecular diagnosis of dysplasia in Barrett’s esophagus

Molecular Biology / Molecular Medicine / Medicine / Gene expression / Levels of selection / Humans / Genetic Testing / Variability / Female / Male / Statistical Significance / Comparative Analysis / Risk factors / Phenotype / Genotype / Esophagus / Molecular Marker / Prognosis / Reproducibility of Results / Genetic variation / Disease Progression / Risk Factors / Boundary Value Problems / Molecular Diagnostic Techniques / Molecular Diagnosis / Genetic Markers / Predictive value of tests / Gene expression profiling / Esophagoscopy / Down-Regulation / Humans / Genetic Testing / Variability / Female / Male / Statistical Significance / Comparative Analysis / Risk factors / Phenotype / Genotype / Esophagus / Molecular Marker / Prognosis / Reproducibility of Results / Genetic variation / Disease Progression / Risk Factors / Boundary Value Problems / Molecular Diagnostic Techniques / Molecular Diagnosis / Genetic Markers / Predictive value of tests / Gene expression profiling / Esophagoscopy / Down-Regulation

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Antimicrobial peptides expression by ocular surface cells in response to Acanthamoeba castellanii: an in vitro study

British / Gene expression / real time PCR / Humans / Statistical Significance / Antimicrobial Peptide / Clinical Sciences / Antimicrobial Cationic Peptides / Optometry and Ophthalmology / Public health systems and services research / Viral Infection / Beta Defensins / In Vitro Studies / Blood Proteins / Down-Regulation / Acanthamoeba keratitis / Ribonucleases / Antimicrobial Peptide / Clinical Sciences / Antimicrobial Cationic Peptides / Optometry and Ophthalmology / Public health systems and services research / Viral Infection / Beta Defensins / In Vitro Studies / Blood Proteins / Down-Regulation / Acanthamoeba keratitis / Ribonucleases

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Tbx3 Represses E-Cadherin Expression and Enhances Melanoma Invasiveness

Cancer / Cell Adhesion / Humans / Melanoma / Calcium Signaling / Phase transition / Transcription Factor / Neoplasm Invasiveness / Cell Proliferation / Base Sequence / Protein Binding / Down-Regulation / Phase transition / Transcription Factor / Neoplasm Invasiveness / Cell Proliferation / Base Sequence / Protein Binding / Down-Regulation

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Repression of rac2 mRNA Expression by Anaplasma phagocytophila Is Essential to the Inhibition of Superoxide Production and Bacterial Proliferation

Immunology / Immunology of the Gut / Cell Division / Humans / The / NADPH oxidase / Neutrophils / mRna expression levels / Ehrlichiosis / Tretinoin / Transfection / Anaplasma Phagocytophilum / Superoxides / Gene expression profiling / Down-Regulation / NADPH oxidase / Neutrophils / mRna expression levels / Ehrlichiosis / Tretinoin / Transfection / Anaplasma Phagocytophilum / Superoxides / Gene expression profiling / Down-Regulation

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The Lifetime of UDP-galactose:Ceramide Galactosyltransferase Is Controlled by a Distinct Endoplasmic Reticulum-associated Degradation (ERAD) Regulated by Sigma-1 Receptor Chaperones

Membrane Proteins / Biological Chemistry / Biological Sciences / Molecular chaperones / Mice / Animals / CHEMICAL SCIENCES / Rats / Substrate Specificity / Subcellular Fractions / Down-Regulation / Animals / CHEMICAL SCIENCES / Rats / Substrate Specificity / Subcellular Fractions / Down-Regulation

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Epithelial-Matrix Interactions: Laminin Downregulates Enterocyte EGF Receptor and IGF-I Receptor Expression

Extracellular Matrix / Western blotting / Cell Division / Cell line / Intestinal Mucosa / Collagen / Animals / Jejunum / Clinical Sciences / Rats / Surgical / Growth Factor / EGF receptor / Growth factor receptor / Down-Regulation / Collagen / Animals / Jejunum / Clinical Sciences / Rats / Surgical / Growth Factor / EGF receptor / Growth factor receptor / Down-Regulation

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Large intra- and inter-individual variability of genes expression levels limits potential predictive value of molecular diagnosis of dysplasia in Barrett’s esophagus

Molecular Biology / Molecular Medicine / Medicine / Gene expression / Levels of selection / Humans / Genetic Testing / Variability / Female / Male / Statistical Significance / Comparative Analysis / Risk factors / Phenotype / Genotype / Esophagus / Molecular Marker / Prognosis / Reproducibility of Results / Genetic variation / Disease Progression / Risk Factors / Boundary Value Problems / Molecular Diagnostic Techniques / Molecular Diagnosis / Genetic Markers / Predictive value of tests / Gene expression profiling / Esophagoscopy / Down-Regulation / Humans / Genetic Testing / Variability / Female / Male / Statistical Significance / Comparative Analysis / Risk factors / Phenotype / Genotype / Esophagus / Molecular Marker / Prognosis / Reproducibility of Results / Genetic variation / Disease Progression / Risk Factors / Boundary Value Problems / Molecular Diagnostic Techniques / Molecular Diagnosis / Genetic Markers / Predictive value of tests / Gene expression profiling / Esophagoscopy / Down-Regulation

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