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Down-Regulation
Down-Regulation
Histone Deacetylase Inhibitors Decrease DNA Methyltransferase-3B Messenger RNA Stability and Down-regulate De novo DNA Methyltransferase Activity in Human Endometrial Cells
Molecular Biology / Cancer / Protein synthesis / Endometrial Cancer / Humans / Female / HIstone Deacetylase / DNA methylation / mRNA stability / Western blot / Protein Expression / Histone deacetylase inhibitor / Hydroxamic Acids / Histone Acetylation / Anticancer Drug / Histone deacetylase inhibitors / Down-Regulation / Female / HIstone Deacetylase / DNA methylation / mRNA stability / Western blot / Protein Expression / Histone deacetylase inhibitor / Hydroxamic Acids / Histone Acetylation / Anticancer Drug / Histone deacetylase inhibitors / Down-Regulation
Defective Regulation of MicroRNA Target Genes in Myoblasts from Facioscapulohumeral Dystrophy Patients
Biological Chemistry / Biological Sciences / Cell Differentiation / Humans / Female / Male / Young Adult / CHEMICAL SCIENCES / Middle Aged / microRNAs / Adult / Muscle development / Gene expression profiling / Down-Regulation / Male / Young Adult / CHEMICAL SCIENCES / Middle Aged / microRNAs / Adult / Muscle development / Gene expression profiling / Down-Regulation
STAT1-deficient mice spontaneously develop estrogen receptor α-positive luminal mammary carcinomas
Breast Cancer / Transcriptome / Humans / Mice / Female / Animals / Cluster Analysis / Epithelial cells / Retrospective Studies / DNA binding proteins / Adenocarcinoma / Down-Regulation / Estrogen receptor alpha / Animals / Cluster Analysis / Epithelial cells / Retrospective Studies / DNA binding proteins / Adenocarcinoma / Down-Regulation / Estrogen receptor alpha
Hypercapnic Acidosis Attenuates Endotoxin-induced Acute Lung Injury
Nonparametric Statistics / Cell Adhesion / Transcription Factors / Probability / Signal Transduction / Humans / Animals / Male / NF-kappa B / Acute respiratory distress syndrome / Vascular endothelium / Nitrogen / American / Acute Lung Injury / Neutrophils / Lipopolysaccharides / Rats / Analysis of Variance / Rat / Survival Rate / Rat Model / Lung Injury / Blood gas analysis / Sensitivity and Specificity / Ischemia–reperfusion / Primary Prevention / Endotoxins / Hypercapnia / Respiratory distress / Pulmonary Gas Exchange / Interleukin / Down-Regulation / Pulmonary Artery / Humans / Animals / Male / NF-kappa B / Acute respiratory distress syndrome / Vascular endothelium / Nitrogen / American / Acute Lung Injury / Neutrophils / Lipopolysaccharides / Rats / Analysis of Variance / Rat / Survival Rate / Rat Model / Lung Injury / Blood gas analysis / Sensitivity and Specificity / Ischemia–reperfusion / Primary Prevention / Endotoxins / Hypercapnia / Respiratory distress / Pulmonary Gas Exchange / Interleukin / Down-Regulation / Pulmonary Artery
Glycodelin reduces carcinoma-associated gene expression in endometrial adenocarcinoma cells
Immunohistochemistry / Gene expression / Humans / Female / Mucin / Glycoproteins / Transfection / Cell Proliferation / Mucins / Antigens / Adenocarcinoma / Down-Regulation / Glycoproteins / Transfection / Cell Proliferation / Mucins / Antigens / Adenocarcinoma / Down-Regulation
EphB receptor activity suppresses colorectal cancer progression
Pharmacology / Biochemistry / Bioinformatics / Evolutionary Biology / Genetics / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / Cancer / Biology / Metabolomics / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Nanotechnology / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Colorectal cancer / Signal Transduction / Astronomy / DNA / Humans / Mutation / Mice / Animals / Cell Signalling / Medical Research / Disease Progression / Adenoma / Earth Science / Down-Regulation / Marine Biology / Neuroscience / Environmental Science / Geophysics / Physics / Materials Science / Quantum Physics / Developmental Biology / Immunology / Climate Change / Molecular Biology / Structural Biology / Genomics / RNA / Computational Biology / Transcriptomics / Biotechnology / Systems Biology / Cancer / Biology / Metabolomics / Cell Cycle / Proteomics / Ecology / Drug Discovery / Evolution / Nanotechnology / Astrophysics / Neurobiology / Medicine / Multidisciplinary / Palaeobiology / Functional Genomics / Nature / Colorectal cancer / Signal Transduction / Astronomy / DNA / Humans / Mutation / Mice / Animals / Cell Signalling / Medical Research / Disease Progression / Adenoma / Earth Science / Down-Regulation
Hyperhomocysteinemia reduces glutamate uptake in parietal cortex of rats
Cognitive Science / Developmental neuroscience / Glutamate / Cerebral Cortex / Aggression / Animals / Male / Parietal Cortex / Homocysteine / Rats / Parietal Lobe / Wistar Rats / Neurosciences / Glutamic Acid / Glutamate Transporter / Down-Regulation / Animals / Male / Parietal Cortex / Homocysteine / Rats / Parietal Lobe / Wistar Rats / Neurosciences / Glutamic Acid / Glutamate Transporter / Down-Regulation
INCREASED SIZE EXCLUSION LIMIT2 Encodes a Putative DEVH Box RNA Helicase Involved in Plasmodesmata Function during Arabidopsis Embryogenesis
Genetics / Plant Biology / Plasmodesmata / Gene expression / Gene Silencing / Protein Structure and Function / Mutation / Arabidopsis / Phenotype / Molecular cloning / microRNAs / Embryonic Development / Seeds / Seedling / Biological markers / Plant cell / Subcellular Fractions / Cell Fate / Embryos / Protein Transport / Biochemistry and cell biology / Down-Regulation / Protein Structure and Function / Mutation / Arabidopsis / Phenotype / Molecular cloning / microRNAs / Embryonic Development / Seeds / Seedling / Biological markers / Plant cell / Subcellular Fractions / Cell Fate / Embryos / Protein Transport / Biochemistry and cell biology / Down-Regulation
Signatures of cinnamyl alcohol dehydrogenase deficiency in poplar lignins
Organic Chemistry / Phytochemistry / Biological Sciences / Populus / Wood / Lignin / Solubility / Phenotype / Enzyme / CHEMICAL SCIENCES / Room Temperature / Gas Chromatography/mass Spectrometry / Populus Deltoides / Sodium Hydroxide / Alcohol Dehydrogenase / Molecular Structure / Down-Regulation / acrolein / Lignin / Solubility / Phenotype / Enzyme / CHEMICAL SCIENCES / Room Temperature / Gas Chromatography/mass Spectrometry / Populus Deltoides / Sodium Hydroxide / Alcohol Dehydrogenase / Molecular Structure / Down-Regulation / acrolein
Knockdown of Cytosolic Glutaredoxin 1 Leads to Loss of Mitochondrial Membrane Potential: Implication in Neurodegenerative Diseases
Immunohistochemistry / Mitochondria / Multidisciplinary / Neurodegenerative Diseases / Antioxidants / Humans / Reactive Oxygen Species / Polymerase Chain Reaction / Animal Model / PLoS one / Mitochondrial dysfunction / Neurodegenerative Disease / Matrix Metalloproteinases / Mitochondrial Permeability Transition Pore / Base Sequence / Mitochondrial Membrane Potential / Outer Membrane Protein / Nucleotides / Down-Regulation / Humans / Reactive Oxygen Species / Polymerase Chain Reaction / Animal Model / PLoS one / Mitochondrial dysfunction / Neurodegenerative Disease / Matrix Metalloproteinases / Mitochondrial Permeability Transition Pore / Base Sequence / Mitochondrial Membrane Potential / Outer Membrane Protein / Nucleotides / Down-Regulation
Albumin suppresses vascular endothelial growth factor via alteration of hypoxia-inducible factor/hypoxia-responsive element pathway
Chronic kidney disease / Signal Transduction / Animals / Rats / Proximal Tubule / Enzyme Linked Immunosorbent Assay / Biochemistry and cell biology / Vascular Endothelial Growth Factor / PROTEASOME INHIBITOR / Down-Regulation / Serum albumin / Enzyme Linked Immunosorbent Assay / Biochemistry and cell biology / Vascular Endothelial Growth Factor / PROTEASOME INHIBITOR / Down-Regulation / Serum albumin
PPAR gamma Co-Activator-1 alpha (PGC-1 alpha) Reduces Amyloid-beta Generation Through a PPAR gamma-Dependent Mechanism
Cognitive Science / Transcription Factors / Humans / Mice / Female / Animals / Male / Clinical Sciences / Aged / Middle Aged / Heat Shock Proteins / Alzheimers Disease / Alzheimer Disease / Neurosciences / Down-Regulation / Animals / Male / Clinical Sciences / Aged / Middle Aged / Heat Shock Proteins / Alzheimers Disease / Alzheimer Disease / Neurosciences / Down-Regulation
Folate deficiency increases mtDNA and D-1 mtDNA deletion in aged brain of mice lacking uracil-DNA glycosylase
Psychology / Aging / DNA repair / Neurodegenerative Diseases / Mitochondrial DNA / Mice / Animals / Peroxisome proliferator-activated receptor / Transcription Factor / Clinical Sciences / Mitochondrial Diseases / mRna expression levels / Experimental / Experimental Neurology / Lactate dehydrogenase / Cognitive Decline / Neurosciences / Citrate Synthase / Brain Diseases / Uracil Dna Glycosylase / Down-Regulation / Mice / Animals / Peroxisome proliferator-activated receptor / Transcription Factor / Clinical Sciences / Mitochondrial Diseases / mRna expression levels / Experimental / Experimental Neurology / Lactate dehydrogenase / Cognitive Decline / Neurosciences / Citrate Synthase / Brain Diseases / Uracil Dna Glycosylase / Down-Regulation
Hypercapnic Acidosis Attenuates Endotoxin-induced Acute Lung Injury
Nonparametric Statistics / Cell Adhesion / Transcription Factors / Probability / Molecular Mechanics / Signal Transduction / Lipopolysaccharide / Humans / Animals / Male / NF-kappa B / Acute respiratory distress syndrome / Vascular endothelium / Nitrogen / American / Acute Lung Injury / Neutrophils / Lipopolysaccharides / Rats / Endothelial cell / Analysis of Variance / Rat / Survival Rate / Mechanical Ventilation / Rat Model / Lactate dehydrogenase / Lung Injury / Blood gas analysis / Sensitivity and Specificity / Ischemia–reperfusion / Primary Prevention / Endotoxins / Hypercapnia / Respiratory distress / Pulmonary Gas Exchange / Interleukin / Down-Regulation / Tidal volume / Pulmonary Artery / Signal Transduction / Lipopolysaccharide / Humans / Animals / Male / NF-kappa B / Acute respiratory distress syndrome / Vascular endothelium / Nitrogen / American / Acute Lung Injury / Neutrophils / Lipopolysaccharides / Rats / Endothelial cell / Analysis of Variance / Rat / Survival Rate / Mechanical Ventilation / Rat Model / Lactate dehydrogenase / Lung Injury / Blood gas analysis / Sensitivity and Specificity / Ischemia–reperfusion / Primary Prevention / Endotoxins / Hypercapnia / Respiratory distress / Pulmonary Gas Exchange / Interleukin / Down-Regulation / Tidal volume / Pulmonary Artery
MicroRNA Expression Profiling in HCV-Infected Human Hepatoma Cells Identifies Potential Anti-Viral Targets Induced by Interferon-α
Multidisciplinary / Humans / Liver / Hepatocellular Carcinoma / PLoS one / Antiviral Agents / Gene expression profiling / Interferon Alpha / Down-Regulation / Antiviral Agents / Gene expression profiling / Interferon Alpha / Down-Regulation
Signatures of cinnamyl alcohol dehydrogenase deficiency in poplar lignins
Organic Chemistry / Phytochemistry / Biological Sciences / Populus / Wood / Lignin / Solubility / Phenotype / Enzyme / CHEMICAL SCIENCES / Room Temperature / Gas Chromatography/mass Spectrometry / Populus Deltoides / Sodium Hydroxide / Alcohol Dehydrogenase / Molecular Structure / Down-Regulation / acrolein / Lignin / Solubility / Phenotype / Enzyme / CHEMICAL SCIENCES / Room Temperature / Gas Chromatography/mass Spectrometry / Populus Deltoides / Sodium Hydroxide / Alcohol Dehydrogenase / Molecular Structure / Down-Regulation / acrolein
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