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Pharmaceutical Chemistry
Pharmaceutical Chemistry
Enzymatic Erosion of Bioartificial Membranes to Control Drug Delivery
Biomedical Engineering / Water / Scanning Electron Microscopy / Drug delivery / Starch / Pharmaceutical Chemistry / Caffeine / Temperature / Drug Delivery Systems / Solubility / Theophylline / Buffers / Polyvinyl alcohol / Solutions / Biocompatible Materials / Drug Carriers / Delayed-Action Preparations / Hydrogen-Ion Concentration / Pharmaceutical Chemistry / Caffeine / Temperature / Drug Delivery Systems / Solubility / Theophylline / Buffers / Polyvinyl alcohol / Solutions / Biocompatible Materials / Drug Carriers / Delayed-Action Preparations / Hydrogen-Ion Concentration
Cyclodextrin complexed insulin encapsulated hydrogel microparticles: An oral delivery system for insulin
Biomedical Engineering / Kinetics / Chitosan / Pharmaceutical Technology / Hydrogels / Pharmaceutical Chemistry / Humans / Controlled release / Blood Glucose / Insulin / Permeability / Animals / Male / Animal Model / Solubility / Oral Delivery / Caco-2 cells / Polyethylene Glycol / Rats / Particle Size / Delivery System / Oral Hypoglycemic Agents / Wistar Rats / Streptozotocin / Polymethyl Methacrylates / Caco 2 Cell / Drug Carriers / Diabetic Rat / Drug Compounding / Polyethylene Glycols / Pharmaceutical Chemistry / Humans / Controlled release / Blood Glucose / Insulin / Permeability / Animals / Male / Animal Model / Solubility / Oral Delivery / Caco-2 cells / Polyethylene Glycol / Rats / Particle Size / Delivery System / Oral Hypoglycemic Agents / Wistar Rats / Streptozotocin / Polymethyl Methacrylates / Caco 2 Cell / Drug Carriers / Diabetic Rat / Drug Compounding / Polyethylene Glycols
Photosensitizer loaded HSA nanoparticles. I: Preparation and photophysical properties
Water / Pharmaceutical Technology / Scanning Electron Microscopy / Nanoparticles / Pharmaceutical Chemistry / Porphyrins / Adsorption / Pharmaceutics / Humans / Ethanol / Solubility / Photochemotherapy / Time Factors / Surface Properties / Freeze Drying / Singlet Oxygen / Bovine Serum Albumin / Drug Carriers / Drug Compounding / Drug Stability / Hydrogen-Ion Concentration / Solvents / Porphyrins / Adsorption / Pharmaceutics / Humans / Ethanol / Solubility / Photochemotherapy / Time Factors / Surface Properties / Freeze Drying / Singlet Oxygen / Bovine Serum Albumin / Drug Carriers / Drug Compounding / Drug Stability / Hydrogen-Ion Concentration / Solvents
Preliminary pharmaceutical development of antimalarial-antibiotic cotherapy as a pre-referral paediatric treatment of fever in malaria endemic areas
Malaria / Pharmaceutical Technology / Powder Diffraction / Crystallization / Pharmaceutical Chemistry / Macromolecular X-Ray Crystallography / Pharmaceutics / Humans / Animals / Endemic Diseases / Solubility / Anti-Bacterial Agents / Antimalarials / Tablets / Age Factors / Rabbits / Azithromycin / Capsules / Excipients / Biological Availability / Macromolecular X-Ray Crystallography / Pharmaceutics / Humans / Animals / Endemic Diseases / Solubility / Anti-Bacterial Agents / Antimalarials / Tablets / Age Factors / Rabbits / Azithromycin / Capsules / Excipients / Biological Availability
In vitro and in vivo profile of 5-[(4′-trifluoromethyl-biphenyl-2-carbonyl)-amino]-1H-indole-2-carboxylic acid benzylmethyl carbamoylamide (dirlotapide), a novel potent MTP inhibitor for obesity
Organic Chemistry / Medicinal Chemistry / Obesity / Pharmaceutical Chemistry / Dogs / Humans / Animals / Drug Design / Enzyme / Food intake / Rats / Carboxylic Acids / Molecular Conformation / Bioorganic and medicinal Chemistry / Hydrogen-Ion Concentration / Carbamates / Humans / Animals / Drug Design / Enzyme / Food intake / Rats / Carboxylic Acids / Molecular Conformation / Bioorganic and medicinal Chemistry / Hydrogen-Ion Concentration / Carbamates
Potential Antibacterial Activity of Carvacrol-Loaded Poly(DL-lactide-co-glycolide) (PLGA) Nanoparticles against Microbial Biofilm
Genetics / Biofilms / Kinetics / Nanoparticles / Pharmaceutical Chemistry / Humans / Drug Delivery Systems / Staphylococcus epidermidis / Molecular sciences / Anti-Bacterial Agents / Monoterpenes / Lactic Acid / Humans / Drug Delivery Systems / Staphylococcus epidermidis / Molecular sciences / Anti-Bacterial Agents / Monoterpenes / Lactic Acid
New 7,8-ethylenedioxy-2,3-benzodiazepines as noncompetitive AMPA receptor antagonists
Organic Chemistry / Pharmaceutical Chemistry / Humans / Mice / DBA / Animals / Drug Design / Benzodiazepines / Rats / Bioorganic and medicinal Chemistry / Structure activity Relationship / Protein Binding / Functional Testing / Animals / Drug Design / Benzodiazepines / Rats / Bioorganic and medicinal Chemistry / Structure activity Relationship / Protein Binding / Functional Testing
Synthesis and pharmacological characterization of 5-phenyl-2-[2-(1-piperidinylcarbonyl)phenyl]-2,3-dihydro-1 H-pyrrolo[1,2- c]imidazol-1-ones: A new class of Neuropeptide S antagonists
Inorganic Chemistry / Organic Chemistry / Medicinal Chemistry / Calcium / Pharmaceutical Chemistry / Macromolecular X-Ray Crystallography / Patch-clamp and imaging techniques / Dogs / Cell line / Adenosine / Brain / Humans / Discrimination Learning / Cerebral Cortex / Mice / Nicotine / Animals / Male / Nicotinic Acetylcholine Receptors / Organometallics / Neurons / CHEMICAL SCIENCES / Rats / Radioligand Assay / Pyridines / BIOCHEMICAL PHARMACOLOGY / Molecular Conformation / Protein Conformation / Alanine / Bioorganic and medicinal Chemistry / Radiopharmaceuticals / Rabbits / Structure activity Relationship / Recombinant Proteins / Ligands / Pain Measurement / Monte Carlo Method / Analgesics / Molecular Structure / Macromolecular X-Ray Crystallography / Patch-clamp and imaging techniques / Dogs / Cell line / Adenosine / Brain / Humans / Discrimination Learning / Cerebral Cortex / Mice / Nicotine / Animals / Male / Nicotinic Acetylcholine Receptors / Organometallics / Neurons / CHEMICAL SCIENCES / Rats / Radioligand Assay / Pyridines / BIOCHEMICAL PHARMACOLOGY / Molecular Conformation / Protein Conformation / Alanine / Bioorganic and medicinal Chemistry / Radiopharmaceuticals / Rabbits / Structure activity Relationship / Recombinant Proteins / Ligands / Pain Measurement / Monte Carlo Method / Analgesics / Molecular Structure
Complementarity Between Public and Commercial Databases: New Opportunities in Medicinal Chemistry Informatics
Computational Biology / Structural Bioinformatics / Pharmaceutical Chemistry / Protein Targeting / Humans / Standardisation / Data Collection / Biological Data / Standardisation / Data Collection / Biological Data
pH and dual redox responsive nanogel based on poly(l-glutamic acid) as potential intracellular drug carrier
Biomedical Engineering / Kinetics / Pharmaceutical Technology / Nanoparticles / Transmission Electron Microscopy / Nanotechnology / Magnetic Resonance Spectroscopy / Pharmaceutical Chemistry / Humans / Controlled release / Micelles / Glutathione / Selenium Compounds / Solubility / Gels / Doxorubicin / Fourier transform infrared spectroscopy / HeLa cells / Drug Carriers / Drug Compounding / Delayed-Action Preparations / Hydrogen-Ion Concentration / Oxidation-Reduction / Polyethylene Glycols / Nanotechnology / Magnetic Resonance Spectroscopy / Pharmaceutical Chemistry / Humans / Controlled release / Micelles / Glutathione / Selenium Compounds / Solubility / Gels / Doxorubicin / Fourier transform infrared spectroscopy / HeLa cells / Drug Carriers / Drug Compounding / Delayed-Action Preparations / Hydrogen-Ion Concentration / Oxidation-Reduction / Polyethylene Glycols
An efficient pH sensitive oral insulin delivery system enhanced by deoxycholic acid
Biomedical Engineering / Kinetics / Pharmaceutical Technology / Scanning Electron Microscopy / Nanoparticles / Transmission Electron Microscopy / Pharmaceutical Chemistry / Controlled release / Insulin / Solubility / Particle Size / Oral Hypoglycemic Agents / Microspheres / Drug Carriers / Drug Compounding / Delayed-Action Preparations / Hydrogen-Ion Concentration / Transmission Electron Microscopy / Pharmaceutical Chemistry / Controlled release / Insulin / Solubility / Particle Size / Oral Hypoglycemic Agents / Microspheres / Drug Carriers / Drug Compounding / Delayed-Action Preparations / Hydrogen-Ion Concentration
Novel artificial cell microencapsulation of a complex gliclazide-deoxycholic bile acid formulation: a characterization study
Rheology / Pharmaceutical Chemistry / Animals / Rats / Alginates / Particle Size / Oral Hypoglycemic Agents / Gliclazide / Type 2 Diabetes Mellitus / Capsules / Excipients / Artificial Cells / Particle Size / Oral Hypoglycemic Agents / Gliclazide / Type 2 Diabetes Mellitus / Capsules / Excipients / Artificial Cells
Probing insulin’s secondary structure after entrapment into alginate/chitosan nanoparticles
Kinetics / Nanoparticle / Chitosan / Pharmaceutical Technology / Nanoparticles / Structural Integrity / Pharmaceutical Chemistry / FTIR / Insulin / Circular Dichroism / Solubility / European / Oral Delivery / Secondary Structure / Protein Secondary Structure Prediction / Alginates / Particle Size / Fourier transform infrared spectroscopy / Oral Hypoglycemic Agents / Drug Carriers / Drug Compounding / Drug Stability / Delayed-Action Preparations / Hydrogen-Ion Concentration / Conformational Change / Fourier transform infrared / D-glucuronic acid / Structural Integrity / Pharmaceutical Chemistry / FTIR / Insulin / Circular Dichroism / Solubility / European / Oral Delivery / Secondary Structure / Protein Secondary Structure Prediction / Alginates / Particle Size / Fourier transform infrared spectroscopy / Oral Hypoglycemic Agents / Drug Carriers / Drug Compounding / Drug Stability / Delayed-Action Preparations / Hydrogen-Ion Concentration / Conformational Change / Fourier transform infrared / D-glucuronic acid
2-Arylpyrimidines: Novel CRF-1 receptor antagonists
Organic Chemistry / Depression / Kinetics / Pharmacokinetics / Pharmaceutical Chemistry / In Vitro / Humans / Animals / Drug Design / Solubility / In Vivo / Rats / Rat / Ether / Molecular Conformation / Bioorganic and medicinal Chemistry / Affinity / Structure activity Relationship / Chemical Synthesis / Molecular Structure / In Vitro / Humans / Animals / Drug Design / Solubility / In Vivo / Rats / Rat / Ether / Molecular Conformation / Bioorganic and medicinal Chemistry / Affinity / Structure activity Relationship / Chemical Synthesis / Molecular Structure
Soy polysaccharide as a novel superdisintegrant in sildenafil citrate sublingual tablets: preparation, characterization, and in vivo evaluation
Pharmaceutical Technology / Polysaccharides / Pharmaceutical Chemistry / Humans / Wettability / Male / Hardness / Solubility / Phosphodiesterase Inhibitors / Soybeans / Adult / Tablets / Excipients / Drug Stability / Biological Availability / Male / Hardness / Solubility / Phosphodiesterase Inhibitors / Soybeans / Adult / Tablets / Excipients / Drug Stability / Biological Availability
Constant size, variable density aerosol particles by ultrasonic spray freeze drying
Scanning Electron Microscopy / Nanoparticles / Pharmaceutical Chemistry / Aerosols / Pharmaceutics / Differential scanning calorimetry / Lasers / Ultrasonics / Temperature / Drug Delivery Systems / High Pressure Liquid Chromatography / X ray diffraction / Particle Size / Freeze Drying / Particulate Matter / Powders / Bovine Serum Albumin / Mannitol / Differential scanning calorimetry / Lasers / Ultrasonics / Temperature / Drug Delivery Systems / High Pressure Liquid Chromatography / X ray diffraction / Particle Size / Freeze Drying / Particulate Matter / Powders / Bovine Serum Albumin / Mannitol
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