Synthesis and pharmacological characterization of 5-phenyl-2-[2-(1-piperidinylcarbonyl)phenyl]-2,3-dihydro-1 H-pyrrolo[1,2- c]imidazol-1-ones: A new class of Neuropeptide S antagonists

June 16, 2017 | Autor: Fabrizio Micheli | Categoría: Inorganic Chemistry, Organic Chemistry, Medicinal Chemistry, Calcium, Pharmaceutical Chemistry, Macromolecular X-Ray Crystallography, Patch-clamp and imaging techniques, Dogs, Cell line, Adenosine, Brain, Humans, Discrimination Learning, Cerebral Cortex, Mice, Nicotine, Animals, Male, Nicotinic Acetylcholine Receptors, Organometallics, Neurons, CHEMICAL SCIENCES, Rats, Radioligand Assay, Pyridines, BIOCHEMICAL PHARMACOLOGY, Molecular Conformation, Protein Conformation, Alanine, Bioorganic and medicinal Chemistry, Radiopharmaceuticals, Rabbits, Structure activity Relationship, Recombinant Proteins, Ligands, Pain Measurement, Monte Carlo Method, Analgesics, Molecular Structure, Macromolecular X-Ray Crystallography, Patch-clamp and imaging techniques, Dogs, Cell line, Adenosine, Brain, Humans, Discrimination Learning, Cerebral Cortex, Mice, Nicotine, Animals, Male, Nicotinic Acetylcholine Receptors, Organometallics, Neurons, CHEMICAL SCIENCES, Rats, Radioligand Assay, Pyridines, BIOCHEMICAL PHARMACOLOGY, Molecular Conformation, Protein Conformation, Alanine, Bioorganic and medicinal Chemistry, Radiopharmaceuticals, Rabbits, Structure activity Relationship, Recombinant Proteins, Ligands, Pain Measurement, Monte Carlo Method, Analgesics, Molecular Structure

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