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Pharmaceutical Chemistry
Pharmaceutical Chemistry
diccionario de perforación español-ingles
Engineering / Earth Sciences / Analytical Chemistry / Nutrition and Dietetics / Kinetics / Mass Spectrometry / Pharmaceutical Chemistry / Multidisciplinary / Biological Sciences / Caspases / Brain / Humans / Diabetes mellitus / Permeability / Enzymatic hydrolysis / Calibration / Female / Animals / Male / Ethanol / Tandem Mass Spectrometry / Cost effectiveness / Gas Chromatography / Trypsin / Risk factors / PLoS one / High Performance Liquid Chromatography / Clinical Sciences / High Pressure Liquid Chromatography / CHEMICAL SCIENCES / Cattle / Intestines / Caco-2 cells / Liquid Chromatography / Electrospray Ionization Mass Spectrometry / Methadone / Hydrazones / Rats / Buffers / Liquid Chromatography / RNA-binding proteins / Reproducibility of Results / Wistar Rats / Risk Factors / Analytical and Bioanalytical Chemistry / Phospholipase D / Analytical Biochemistry / Amino Acid Sequence / Sensitivity and Specificity / Hydrolysis / Vitamin D Deficiency / Drug Stability / Ions / Area Under Curve / Arachidonic Acid / Biochemistry and cell biology / Molecular Sequence Data / Mass Spectrometry / Pharmaceutical Chemistry / Multidisciplinary / Biological Sciences / Caspases / Brain / Humans / Diabetes mellitus / Permeability / Enzymatic hydrolysis / Calibration / Female / Animals / Male / Ethanol / Tandem Mass Spectrometry / Cost effectiveness / Gas Chromatography / Trypsin / Risk factors / PLoS one / High Performance Liquid Chromatography / Clinical Sciences / High Pressure Liquid Chromatography / CHEMICAL SCIENCES / Cattle / Intestines / Caco-2 cells / Liquid Chromatography / Electrospray Ionization Mass Spectrometry / Methadone / Hydrazones / Rats / Buffers / Liquid Chromatography / RNA-binding proteins / Reproducibility of Results / Wistar Rats / Risk Factors / Analytical and Bioanalytical Chemistry / Phospholipase D / Analytical Biochemistry / Amino Acid Sequence / Sensitivity and Specificity / Hydrolysis / Vitamin D Deficiency / Drug Stability / Ions / Area Under Curve / Arachidonic Acid / Biochemistry and cell biology / Molecular Sequence Data
Novel artificial cell microencapsulation of a complex gliclazide-deoxycholic bile acid formulation: a characterization study
Rheology / Pharmaceutical Chemistry / Animals / Rats / Alginates / Particle Size / Oral Hypoglycemic Agents / Gliclazide / Type 2 Diabetes Mellitus / Capsules / Excipients / Artificial Cells / D-glucuronic acid / Particle Size / Oral Hypoglycemic Agents / Gliclazide / Type 2 Diabetes Mellitus / Capsules / Excipients / Artificial Cells / D-glucuronic acid
In vitro and in vivo profile of 5-[(4′-trifluoromethyl-biphenyl-2-carbonyl)-amino]-1H-indole-2-carboxylic acid benzylmethyl carbamoylamide (dirlotapide), a novel potent MTP inhibitor for obesity
Organic Chemistry / Medicinal Chemistry / Obesity / Pharmacokinetics / Pharmaceutical Chemistry / Dogs / Cell line / In Vitro / Humans / Models / Animals / Drug Design / Enzyme / Food intake / In Vivo / Rats / Rat / Carboxylic Acids / Molecular Conformation / Bioorganic and medicinal Chemistry / Hydrogen-Ion Concentration / Chemical Synthesis / Carbamates / Selectivity / Dogs / Cell line / In Vitro / Humans / Models / Animals / Drug Design / Enzyme / Food intake / In Vivo / Rats / Rat / Carboxylic Acids / Molecular Conformation / Bioorganic and medicinal Chemistry / Hydrogen-Ion Concentration / Chemical Synthesis / Carbamates / Selectivity
Complementary medicinal chemistry‐driven strategies toward new antitrypanosomal and antileishmanial lead drug candidates
Immunology / Medical Microbiology / Treatment / Drug Discovery / Leishmania / Pharmaceutical Chemistry / Leishmaniasis / Humans / Animals / Lead / Drug Design / Complementary Medicine / Trypanosoma / Trypanosomiasis / Trypanocidal Agents / Quinazolines / Pharmaceutical Chemistry / Leishmaniasis / Humans / Animals / Lead / Drug Design / Complementary Medicine / Trypanosoma / Trypanosomiasis / Trypanocidal Agents / Quinazolines
Zwitterionic uracil derivatives as potent GnRH receptor antagonists with improved pharmaceutical properties
Organic Chemistry / Kinetics / Pharmaceutical Chemistry / Humans / Drug Design / Peptides / Enzyme Inhibition / Gonadotropin Releasing Hormone / Bioorganic and medicinal Chemistry / Structure activity Relationship / Ions / Molecular Structure / Peptides / Enzyme Inhibition / Gonadotropin Releasing Hormone / Bioorganic and medicinal Chemistry / Structure activity Relationship / Ions / Molecular Structure
Soy polysaccharide as a novel superdisintegrant in sildenafil citrate sublingual tablets: preparation, characterization, and in vivo evaluation
Pharmaceutical Technology / Polysaccharides / Pharmaceutical Chemistry / Humans / Wettability / Male / Hardness / Solubility / Phosphodiesterase Inhibitors / Soybeans / Adult / Tablets / Excipients / Drug Stability / Biological Availability / Male / Hardness / Solubility / Phosphodiesterase Inhibitors / Soybeans / Adult / Tablets / Excipients / Drug Stability / Biological Availability
Micro-particle corrugation, adhesion and inhalation aerosol efficiency
Scanning Electron Microscopy / Nanoparticles / Pharmaceutical Chemistry / Atomic Force Microscopy / Adhesion / Aerosols / AFM / Colloids / Root-Mean Square Error / Surface Morphology / Efficiency / DPI / European / Particle / Powder / Particle Size / Bovine Serum Albumin / Fine Particles / Performance Measure / Aerosols / AFM / Colloids / Root-Mean Square Error / Surface Morphology / Efficiency / DPI / European / Particle / Powder / Particle Size / Bovine Serum Albumin / Fine Particles / Performance Measure
Novel artificial cell microencapsulation of a complex gliclazide-deoxycholic bile acid formulation: a characterization study
Rheology / Pharmaceutical Chemistry / Animals / Rats / Alginates / Particle Size / Oral Hypoglycemic Agents / Gliclazide / Type 2 Diabetes Mellitus / Capsules / Excipients / Artificial Cells / Particle Size / Oral Hypoglycemic Agents / Gliclazide / Type 2 Diabetes Mellitus / Capsules / Excipients / Artificial Cells
Novel composite core-shell nanoparticles as busulfan carriers
Biomedical Engineering / Complement activation / Pharmaceutical Technology / Drug delivery / Nanoparticles / Polymers / Pharmaceutical Chemistry / Controlled release / Solubility / Poly Ethylene Glycol / Surface Properties / Freeze Drying / Surface Charge / Chemical Composition / Liquid Scintillation Counting / Zeta Potential / Drug Carriers / Drug Release / Lactones / Cyanoacrylates / Polymers / Pharmaceutical Chemistry / Controlled release / Solubility / Poly Ethylene Glycol / Surface Properties / Freeze Drying / Surface Charge / Chemical Composition / Liquid Scintillation Counting / Zeta Potential / Drug Carriers / Drug Release / Lactones / Cyanoacrylates
Peptide stability in drug development: A comparison of peptide reactivity in different biological media
Rheumatoid Arthritis / Drug development / Pharmaceutical Chemistry / Humans / Liver / Mice / Pharmaceutical Sciences / Animals / Peptides / Cattle / Shell Half-Life / Molecular weight / Amino Acid Sequence / Structure activity Relationship / Drug Stability / Synovial-fluid / Mice / Pharmaceutical Sciences / Animals / Peptides / Cattle / Shell Half-Life / Molecular weight / Amino Acid Sequence / Structure activity Relationship / Drug Stability / Synovial-fluid
Peptide stability in drug development: A comparison of peptide reactivity in different biological media
Rheumatoid Arthritis / Drug development / Pharmaceutical Chemistry / Humans / Liver / Mice / Pharmaceutical Sciences / Animals / Peptides / Cattle / Shell Half-Life / Molecular weight / Amino Acid Sequence / Structure activity Relationship / Drug Stability / Synovial-fluid / Mice / Pharmaceutical Sciences / Animals / Peptides / Cattle / Shell Half-Life / Molecular weight / Amino Acid Sequence / Structure activity Relationship / Drug Stability / Synovial-fluid
Preparation and characterization of spironolactone-loaded nano-emulsions for extemporaneous applications
Scanning Electron Microscopy / Crystallization / Nanoparticles / Drug development / Pharmaceutical Chemistry / Oils / Pharmaceutics / Differential scanning calorimetry / Diuretics / Solubility / Chemical Precipitation / Particle Size / Fats / Surface Active Agents / Water soluble polymers / Solid Dispersion / Microspheres / Spray Drying / Drug Carriers / Excipients / Biological Availability / Polyethylene Glycols / Solvents / Oils / Pharmaceutics / Differential scanning calorimetry / Diuretics / Solubility / Chemical Precipitation / Particle Size / Fats / Surface Active Agents / Water soluble polymers / Solid Dispersion / Microspheres / Spray Drying / Drug Carriers / Excipients / Biological Availability / Polyethylene Glycols / Solvents
Synthesis and biological evaluation of unprecedented classes of spiro-β-lactams and azido-β-lactams as acyl-CoA:cholesterol acyltransferase inhibitors
Organic Chemistry / Catalysis / Kinetics / Enzyme Inhibitors / Pharmaceutical Chemistry / Humans / Cholesterol / Drug Design / Absorption / Beta Lactams / Molecular Conformation / Bioorganic and medicinal Chemistry / Humans / Cholesterol / Drug Design / Absorption / Beta Lactams / Molecular Conformation / Bioorganic and medicinal Chemistry
Novel design principle validated: Glucopyranosylidene-spiro-oxathiazole as new nanomolar inhibitor of glycogen phosphorylase, potential antidiabetic agent
Organic Chemistry / Kinetics / Pharmaceutical Chemistry / Glucose / Animals / Drug Design / Oral Hypoglycemic Agents / Bioorganic and medicinal Chemistry / Rabbits / Thiazoles / Glycogen / Drug Design / Oral Hypoglycemic Agents / Bioorganic and medicinal Chemistry / Rabbits / Thiazoles / Glycogen
Dendrosomal curcumin nanoformulation downregulates pluripotency genes via miR-145 activation in U87MG glioblastoma cells
Cancer / Cell Cycle / Nanomedicine / Cancer Biology / Nanotechnology / Transcription Factors / Pharmaceutical Chemistry / Apoptosis / Caspases / miRNA / Humans / Glioblastoma / Curcumin / Cell Death / microRNAs / Nanocapsules / Drug Carriers / Drug Stability / Molecular Targeted Therapy / Down-Regulation / Transcription Factors / Pharmaceutical Chemistry / Apoptosis / Caspases / miRNA / Humans / Glioblastoma / Curcumin / Cell Death / microRNAs / Nanocapsules / Drug Carriers / Drug Stability / Molecular Targeted Therapy / Down-Regulation
Enzymatic Erosion of Bioartificial Membranes to Control Drug Delivery
Biomedical Engineering / Water / Scanning Electron Microscopy / Drug delivery / Starch / Pharmaceutical Chemistry / Caffeine / Temperature / Drug Delivery Systems / Solubility / Theophylline / Buffers / Polyvinyl alcohol / Solutions / Biocompatible Materials / Drug Carriers / Delayed-Action Preparations / Hydrogen-Ion Concentration / Pharmaceutical Chemistry / Caffeine / Temperature / Drug Delivery Systems / Solubility / Theophylline / Buffers / Polyvinyl alcohol / Solutions / Biocompatible Materials / Drug Carriers / Delayed-Action Preparations / Hydrogen-Ion Concentration
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