Gene Silencing

Processing of Drosophila endo-siRNAs depends on a specific Loquacious isoform

RNA / Drosophila melanogaster / Gene Silencing / Germ Cells / Animals / Biochemistry and cell biology

NLRP3 gene silencing ameliorates diabetic cardiomyopathy in a type 2 diabetes rat model

Apoptosis / Multidisciplinary / Gene Silencing / Signal Transduction / Cell line / Reactive Oxygen Species / Animals / NF-kappa B / PLoS one / Caspase / Rats / Inflammasomes / Type 2 Diabetes Mellitus / Gene Expression Regulation / Reactive Oxygen Species / Animals / NF-kappa B / PLoS one / Caspase / Rats / Inflammasomes / Type 2 Diabetes Mellitus / Gene Expression Regulation

A Locked Nucleic Acid Antisense Oligonucleotide (LNA) Silences PCSK9 and Enhances LDLR Expression In Vitro and In Vivo

Flow Cytometry / Multidisciplinary / Gene Silencing / Metabolic syndrome / Cell line / Humans / Mice / Animals / Cell Death / Polymerase Chain Reaction / PLoS one / LDL-cholesterol / Cardiovascular Risk Factor / Alanine Aminotransferase / Antisense Oligonucleotide Drugs / Familial Hypercholesterolemia / Cell Survival / Low Density Lipoprotein (LDL) / Intracellular Space / Oligonucleotides / Humans / Mice / Animals / Cell Death / Polymerase Chain Reaction / PLoS one / LDL-cholesterol / Cardiovascular Risk Factor / Alanine Aminotransferase / Antisense Oligonucleotide Drugs / Familial Hypercholesterolemia / Cell Survival / Low Density Lipoprotein (LDL) / Intracellular Space / Oligonucleotides

Arl13b regulates endocytic recycling traffic

Multidisciplinary / Gene Silencing / Humans / Endocytosis / Cluster Analysis / Transferrin / Actin Cytoskeleton / HeLa cells / Protein Binding / Endosomes / Protein Transport / Transferrin / Actin Cytoskeleton / HeLa cells / Protein Binding / Endosomes / Protein Transport

Mammalian RNAi: a practical guide

Technology / Gene Silencing / Genetic Engineering / Biological Sciences / RNA interference / Humans / Animals / Gene Targeting / Transfection / Gene expression profiling / Humans / Animals / Gene Targeting / Transfection / Gene expression profiling

Mammalian RNAi: a practical guide

Technology / Gene Silencing / Genetic Engineering / Biological Sciences / RNA interference / Humans / Animals / Gene Targeting / Transfection / Gene expression profiling / Humans / Animals / Gene Targeting / Transfection / Gene expression profiling

Antivirulence Genes: Insights into Pathogen Evolution through Gene Loss

Molecular Evolution / Gene Silencing / Biological Sciences / Infection and immunity / Virulence / Humans / Mice / Animals / Bacteria / Humans / Mice / Animals / Bacteria

Gene loss and silencing in Tragopogon miscellus (Asteraceae): comparison of natural and synthetic allotetraploids

Evolutionary Biology / Genetics / Gene Silencing / Polyploidy / Heredity / Plant Genome Project

Adenosine modulates vascular endothelial growth factor expression via hypoxia-inducible factor-1 in human glioblastoma cells

Gene Silencing / Molecular Mechanics / Western blotting / Cell line / Adenosine / Humans / Glioblastoma / Mitogen Activated Protein Kinase / Protein Expression / BIOCHEMICAL PHARMACOLOGY / Triazoles / Enzyme Linked Immunosorbent Assay / Vascular Endothelial Growth Factor / Humans / Glioblastoma / Mitogen Activated Protein Kinase / Protein Expression / BIOCHEMICAL PHARMACOLOGY / Triazoles / Enzyme Linked Immunosorbent Assay / Vascular Endothelial Growth Factor

Transient Co-Expression of Post-Transcriptional Gene Silencing Suppressors for Increased in Planta Expression of a Recombinant Anthrax Receptor Fusion Protein

Genetics / Tobacco / Gene expression / Gene Silencing / von Willebrand factor / Molecular Farming / Transient / Molecular sciences / Fusion Protein / Plant Leaves / Molecular Farming / Transient / Molecular sciences / Fusion Protein / Plant Leaves

Comprehensive Protein-Based Artificial MicroRNA Screens for Effective Gene Silencing in Plants

Genetics / Plant Biology / Tobacco / Gene Silencing / Plants / Oryza Sativa / Arabidopsis / microRNAs / Zea mays / Protoplasts / Base Sequence / PLANT PROTEINS / Lycopersicon esculentum / Biochemistry and cell biology / Immunoblotting / Oryza Sativa / Arabidopsis / microRNAs / Zea mays / Protoplasts / Base Sequence / PLANT PROTEINS / Lycopersicon esculentum / Biochemistry and cell biology / Immunoblotting

Silencing of natural interferon producing cell activation by porcine circovirus type 2 DNA

Immunology / Cytokines / Gene Silencing / Signal Transduction / Toll Like Receptors / Animals / Capsid / Swine / Immune Tolerance / Interferon Alpha / Animals / Capsid / Swine / Immune Tolerance / Interferon Alpha

Recombinant mammalian DNA methyltransferase activity on model transcriptional gene silencing short RNA–DNA heteroduplex substrates

Gene Silencing / Biological Sciences / Methylation / DNA methyltransferases / DNA methylation / CpG islands / Post-Transcriptional Gene Regulation / Biochemical / CHEMICAL SCIENCES / Substrate Specificity / Recombinant Proteins / Sulfates / CpG islands / Post-Transcriptional Gene Regulation / Biochemical / CHEMICAL SCIENCES / Substrate Specificity / Recombinant Proteins / Sulfates

Farnesoid X receptor represses hepatic lipase gene expression

RNA / Transcription Factors / Gene expression / Gene Silencing / Cell line / Humans / Liver / Lipid metabolism / Lipoprotein(a) / Enzyme / Cell nucleus / Time Dependent / Time Factors / Hepatocytes / Lipoproteins / High Density Lipoprotein / Transfection / Lipid / Enzymatic Activity / DNA binding proteins / Lipase / Ligands / Biochemistry and cell biology / Down-Regulation / Humans / Liver / Lipid metabolism / Lipoprotein(a) / Enzyme / Cell nucleus / Time Dependent / Time Factors / Hepatocytes / Lipoproteins / High Density Lipoprotein / Transfection / Lipid / Enzymatic Activity / DNA binding proteins / Lipase / Ligands / Biochemistry and cell biology / Down-Regulation

Embryo-specific silencing of a transporter reduces phytic acid content of maize and soybean seeds

Multidisciplinary / Animal Nutrition / Gene Silencing / Nature / Genetic Engineering / Negative Affect / Maize / Soybean / Wild edible plants / Soybeans / Zea mays / Seeds / Base Sequence / Embryos / Molecular Sequence Data / Dry Weight / Negative Affect / Maize / Soybean / Wild edible plants / Soybeans / Zea mays / Seeds / Base Sequence / Embryos / Molecular Sequence Data / Dry Weight

Embryo-specific silencing of a transporter reduces phytic acid content of maize and soybean seeds

Multidisciplinary / Animal Nutrition / Gene Silencing / Nature / Genetic Engineering / Negative Affect / Maize / Soybean / Wild edible plants / Soybeans / Zea mays / Seeds / Base Sequence / Embryos / Molecular Sequence Data / Dry Weight / Negative Affect / Maize / Soybean / Wild edible plants / Soybeans / Zea mays / Seeds / Base Sequence / Embryos / Molecular Sequence Data / Dry Weight

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