Gene Silencing

TGF-β 1 Induces Human Alveolar Epithelial to Mesenchymal Cell Transition(EMT)

Gene Silencing / Epithelial-Mesenchymal Transition / Phase Contrast Microscopy / Respiratory / Western blot / Monoclonal Antibody / Idiopathic Pulmonary Fibrosis / Monoclonal Antibody / Idiopathic Pulmonary Fibrosis

Pyrrole-imidazole polyamide targeting transforming growth factor β1 ameliorates encapsulating peritoneal sclerosis

Extracellular Matrix / Gene Silencing / Animals / Male / Rats / Peritoneal Dialysis / Transforming Growth Factor Beta / Wistar Rats / Imidazoles / Peritoneum / Peritoneal Dialysis / Transforming Growth Factor Beta / Wistar Rats / Imidazoles / Peritoneum

Epigenetic Silencing of Gene Expression in Entamoeba histolytica

Gene Silencing / Animals / Entamoeba histolytica

Hydroxyproline-based DNA mimics provide an efficient gene silencing in vitro and in vivo

Confocal Microscopy / Gene Silencing / Biological Sciences / DNA / Xenopus / Environmental Sciences / Animals / Peptide Nucleic Acids / Nucleic Acids / Green Fluorescent Protein / Molecular Mimicry / Basic Research / Hydroxyproline / Cell free System / Embryos / Protein Biosynthesis / Environmental Sciences / Animals / Peptide Nucleic Acids / Nucleic Acids / Green Fluorescent Protein / Molecular Mimicry / Basic Research / Hydroxyproline / Cell free System / Embryos / Protein Biosynthesis

MYC translocation-negative classical Burkitt lymphoma cases: an alternative pathogenetic mechanism involving miRNA deregulation

Pathology / Micro Rna / Cancer / Adolescent / Gene expression / Gene Silencing / Cytogenetics / RNA interference / Humans / Child / Female / Male / Young Adult / Mechanism / The / Small RNA / Clinical Sciences / microRNAs / Adult / Immunoglobulin / Chromosome Translocation / Cell Growth / Gene Silencing / Cytogenetics / RNA interference / Humans / Child / Female / Male / Young Adult / Mechanism / The / Small RNA / Clinical Sciences / microRNAs / Adult / Immunoglobulin / Chromosome Translocation / Cell Growth

In Vivo Release of Mitotic Silencing of Ribosomal Gene Transcription Does Not Give Rise to Precursor Ribosomal RNA Processing

Cell Cycle / Cell Biology / RNA polymerase / Gene Silencing / Biological Sciences / Mitosis / Humans / ribosomal RNA / Colchicine / HeLa cells / Isoenzymes / The cell / Ribosomal DNA / Okadaic acid / Mitosis / Humans / ribosomal RNA / Colchicine / HeLa cells / Isoenzymes / The cell / Ribosomal DNA / Okadaic acid

Intracellular Insulin-like Growth Factor-1 Induces Bcl-2 Expression in Airway Epithelial Cells

Immunology / Cystic Fibrosis / Immunology of the Gut / Gene Silencing / Humans / Mice / Chronic Disease / Animals / Male / Lipopolysaccharides / Rats / Epithelial cells / Protein Binding / Gene Expression Regulation / Gene expression profiling / Mice / Chronic Disease / Animals / Male / Lipopolysaccharides / Rats / Epithelial cells / Protein Binding / Gene Expression Regulation / Gene expression profiling

Nephrin Deficiency Activates NF- B and Promotes Glomerular Injury

Nephrology / Urology / Membrane Proteins / Gene Silencing / Dogs / Cell line / Humans / Mice / Animals / NF-kappa B / The / Clinical Sciences / Deficiency / Proteinuria / Deficit / Cytoplasm / Podocytes / Glomerulonephritis / Cell line / Humans / Mice / Animals / NF-kappa B / The / Clinical Sciences / Deficiency / Proteinuria / Deficit / Cytoplasm / Podocytes / Glomerulonephritis

Epigenetic Silencing of Host Cell Defense Genes Enhances Intracellular Survival of the Rickettsial Pathogen Anaplasma phagocytophilum

Microbiology / Immunology / Medical Microbiology / Gene Silencing / Humans / HIstone Deacetylase / Chromatin / Ehrlichiosis / Host Pathogen Interactions / Anaplasma Phagocytophilum / Gene Expression Regulation / Histone deacetylases / Host Defense / HIstone Deacetylase / Chromatin / Ehrlichiosis / Host Pathogen Interactions / Anaplasma Phagocytophilum / Gene Expression Regulation / Histone deacetylases / Host Defense

A Locked Nucleic Acid Antisense Oligonucleotide (LNA) Silences PCSK9 and Enhances LDLR Expression In Vitro and In Vivo

Flow Cytometry / Multidisciplinary / Gene Silencing / Metabolic syndrome / Cell line / Humans / Mice / Animals / Cell Death / Polymerase Chain Reaction / PLoS one / LDL-cholesterol / Cardiovascular Risk Factor / Alanine Aminotransferase / Antisense Oligonucleotide Drugs / Familial Hypercholesterolemia / Cell Survival / Low Density Lipoprotein (LDL) / Intracellular Space / Oligonucleotides / Humans / Mice / Animals / Cell Death / Polymerase Chain Reaction / PLoS one / LDL-cholesterol / Cardiovascular Risk Factor / Alanine Aminotransferase / Antisense Oligonucleotide Drugs / Familial Hypercholesterolemia / Cell Survival / Low Density Lipoprotein (LDL) / Intracellular Space / Oligonucleotides

shRNA Expression Constructs Designed Directly from siRNA Oligonucleotide Sequences

Algorithms / Technology / RNA / Gene expression / Gene Silencing / Biological Sciences / RNA interference / Cell line / Humans / Polymerase Chain Reaction / Molecular Biotechnology / Base Sequence / Structure activity Relationship / Biological Sciences / RNA interference / Cell line / Humans / Polymerase Chain Reaction / Molecular Biotechnology / Base Sequence / Structure activity Relationship

Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy

Multidisciplinary / Gene Silencing / Nature / Genetic Engineering / Gene Targeting / Transfection / Gene Expression Regulation / Transfection / Gene Expression Regulation

Design of siRNAs producing unstructured guide-RNAs results in improved RNA interference efficiency

Algorithms / Thermodynamics / RNA / Biotechnology / RNA silencing / Multidisciplinary / Gene Silencing / Nature / RNA interference / Cell line / Humans / Plasmids / microRNAs / Secondary Structure / Degeneration / RNA Structure / Structure Determination / RNA Secondary Structure / Nucleic Acid Conformation / Nucleotides / Multidisciplinary / Gene Silencing / Nature / RNA interference / Cell line / Humans / Plasmids / microRNAs / Secondary Structure / Degeneration / RNA Structure / Structure Determination / RNA Secondary Structure / Nucleic Acid Conformation / Nucleotides

Control of specific gene expression in mammalian cells by co-expression of long complementary RNAs

Gene expression / Gene Silencing / Cell line / Humans / Animals / Gene Function / Cytoplasm / double-stranded RNA / Biochemistry and cell biology / Gene Function / Cytoplasm / double-stranded RNA / Biochemistry and cell biology

Control of specific gene expression in mammalian cells by co-expression of long complementary RNAs

Gene expression / Gene Silencing / Cell line / Humans / Animals / Gene Function / Cytoplasm / double-stranded RNA / Biochemistry and cell biology / Gene Function / Cytoplasm / double-stranded RNA / Biochemistry and cell biology

Differential fates of biomolecules delivered to target cells via extracellular vesicles

Flow Cytometry / Fluorescence Microscopy / Confocal Microscopy / Atomic Force Microscopy / Apoptosis / Multidisciplinary / Gene Silencing / DNA / Lipids / Humans / Mice / Animals / Exosomes / Plasmids / Cell communication / Polyethylene Glycols / Multidisciplinary / Gene Silencing / DNA / Lipids / Humans / Mice / Animals / Exosomes / Plasmids / Cell communication / Polyethylene Glycols

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