DNA damage

Integrin activation suppresses etoposide-induced DNA strand breakage in cultured murine tumor-derived endothelial cells

Cancer / Cell Adhesion / DNA damage / Antibodies / Basement Membrane / Mice / Animals / Vascular endothelium / Fibrosarcoma / Gelatin / Integrins / Lipopolysaccharides / Cell Survival / Extracellular Matrix Proteins / Mice / Animals / Vascular endothelium / Fibrosarcoma / Gelatin / Integrins / Lipopolysaccharides / Cell Survival / Extracellular Matrix Proteins

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Long-term XPC Silencing Reduces DNA Double-Strand Break Repair

Genetics / Cancer / DNA replication / Gamma Rays / DNA damage / DNA repair / Gene expression / Gene Silencing / RNA interference / Humans / Nuclear Structure / Nucleotide Excision Repair / Spectrum / HeLa cells / DNA binding proteins / DNA repair / Gene expression / Gene Silencing / RNA interference / Humans / Nuclear Structure / Nucleotide Excision Repair / Spectrum / HeLa cells / DNA binding proteins

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Extract from Armoracia rusticana and Its Flavonoid Components Protect Human Lymphocytes against Oxidative Damage Induced by Hydrogen Peroxide

Organic Chemistry / Oxidative Stress / Flavonoids / DNA damage / Humans / Hydrogen Peroxide / Molecules / Plant extracts / Lymphocytes / Hydrogen Peroxide / Molecules / Plant extracts / Lymphocytes

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PIGA (N,N-Di-n-butyl-5-chloro-2-(4-chlorophenyl)indol-3-ylglyoxylamide), a New Mitochondrial Benzodiazepine-Receptor Ligand, Induces Apoptosis in C6 glioma Cells

Mitochondria / DNA damage / Apoptosis / Caspases / Glioma / Animals / Caspase / Rats / Time Factors / Antineoplastic Agents / Ligands / Biochemistry and cell biology / Animals / Caspase / Rats / Time Factors / Antineoplastic Agents / Ligands / Biochemistry and cell biology

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Decreased Mitochondrial DNA Mutagenesis in Human Colorectal Cancer

Genetics / Oxidative Stress / DNA damage / Colorectal cancer / Mitochondrial DNA / Humans / Mutagenesis / Glucose / Glucose Metabolism / Reactive Oxygen Species / Female / Male / Glycolysis / Mitochondrial Genome / Aged / Middle Aged / Oxidative Damage / Oxidative phosphorylation / Experimental Tests / Genomic instability / PLoS Genetics / Humans / Mutagenesis / Glucose / Glucose Metabolism / Reactive Oxygen Species / Female / Male / Glycolysis / Mitochondrial Genome / Aged / Middle Aged / Oxidative Damage / Oxidative phosphorylation / Experimental Tests / Genomic instability / PLoS Genetics

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Oxygen Free Radical Damage to DNA. TRANSLESION SYNTHESIS BY HUMAN DNA POLYMERASE eta AND RESISTANCE TO EXONUCLEASE ACTION AT CYCLOPURINE DEOXYNUCLEOSIDE RESIDUES

Free Radicals / DNA replication / Biological Chemistry / DNA damage / DNA repair / Biological Sciences / Humans / Reactive Oxygen Species / CHEMICAL SCIENCES / Oligonucleotides / Molecular Structure / Biological Sciences / Humans / Reactive Oxygen Species / CHEMICAL SCIENCES / Oligonucleotides / Molecular Structure

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Biomonitoring human exposure to environmental carcinogenic chemicals

Petroleum / Environmental Monitoring / DNA damage / Humans / Mutagenesis / Polycyclic aromatic hydrocarbons (PAHs) / Occupational Exposure / Nitrogen Oxides / Mutagens / Environmental Exposure / Styrene / Blood Proteins / Case Control Studies / Polycyclic aromatic hydrocarbons (PAHs) / Occupational Exposure / Nitrogen Oxides / Mutagens / Environmental Exposure / Styrene / Blood Proteins / Case Control Studies

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p16(INK) (4a) deficiency promotes DNA hyper-replication and genetic instability in melanocytes

DNA replication / DNA damage / Biological Sciences / Humans / Histones / Genomic instability / Cell cycle checkpoints / Melanocytes / Cell Proliferation / retinoblastoma protein (RB1). / Genomic instability / Cell cycle checkpoints / Melanocytes / Cell Proliferation / retinoblastoma protein (RB1).

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Environmental and chemical carcinogenesis

Genetics / Life Style / Tobacco / DNA damage / Molecular Epidemiology / Lung Cancer / Humans / Tobacco Use / Animals / Laboratory Animals / Glutathione / Detoxification / Carcinogens / Enzyme / Aflatoxins / Colon cancer / Neoplasms / Genetic Polymorphism / Meat products / North American / Liver cancer / Hepatitis B virus / Weight of Evidence / Epidemiologic Studies / Environment / Cancer Risk / Environmental Exposure / Tumor Progression / Nucleotides / Lung Cancer / Humans / Tobacco Use / Animals / Laboratory Animals / Glutathione / Detoxification / Carcinogens / Enzyme / Aflatoxins / Colon cancer / Neoplasms / Genetic Polymorphism / Meat products / North American / Liver cancer / Hepatitis B virus / Weight of Evidence / Epidemiologic Studies / Environment / Cancer Risk / Environmental Exposure / Tumor Progression / Nucleotides

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Environmental and chemical carcinogenesis

Genetics / Life Style / Tobacco / DNA damage / Molecular Epidemiology / Lung Cancer / Humans / Tobacco Use / Animals / Laboratory Animals / Glutathione / Detoxification / Carcinogens / Enzyme / Aflatoxins / Colon cancer / Neoplasms / Genetic Polymorphism / Meat products / North American / Liver cancer / Hepatitis B virus / Weight of Evidence / Epidemiologic Studies / Environment / Cancer Risk / Environmental Exposure / Tumor Progression / Nucleotides / Lung Cancer / Humans / Tobacco Use / Animals / Laboratory Animals / Glutathione / Detoxification / Carcinogens / Enzyme / Aflatoxins / Colon cancer / Neoplasms / Genetic Polymorphism / Meat products / North American / Liver cancer / Hepatitis B virus / Weight of Evidence / Epidemiologic Studies / Environment / Cancer Risk / Environmental Exposure / Tumor Progression / Nucleotides

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Amsacta moorei entomopoxvirus encodes a functional DNA photolyase (AMV025)

Zoology / DNA damage / DNA repair / Phylogeny / Escherichia coli / Animals / Invertebrate Pathology / UV irradiation / Moths / Lymantria Dispar / Amino Acid Sequence / Invertebrate / C-DNA Synthesis / Transient Expression / Animals / Invertebrate Pathology / UV irradiation / Moths / Lymantria Dispar / Amino Acid Sequence / Invertebrate / C-DNA Synthesis / Transient Expression

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In Vivo and In Vitro Evidence for Placental DNA Damage in Preeclampsia

Immunohistochemistry / Confocal Microscopy / DNA damage / Multidisciplinary / Western blotting / Pregnancy / Humans / Reactive Oxygen Species / Female / PLoS one / Histones / Cell nucleus / Adult / Analysis of Variance / Stromal Cells / Pre Eclampsia / Pregnancy / Humans / Reactive Oxygen Species / Female / PLoS one / Histones / Cell nucleus / Adult / Analysis of Variance / Stromal Cells / Pre Eclampsia

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Uracil-DNA glycosylase activities in hyperthermophilic micro-organisms

Enzyme Inhibitors / DNA damage / DNA repair / Biological Sciences / Archaea / Sulfolobus / Hydrolysis / Hot Temperature / Sulfolobus / Hydrolysis / Hot Temperature

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Beneficial effects of Mn(III)tetrakis (4-benzoic acid) porphyrin (MnTBAP), a superoxide dismutase mimetic, in zymosan-induced shock

Immunohistochemistry / DNA damage / Energy Metabolism / Peroxidase / Nitric oxide / Shock / Animals / Male / Nitrates / Bilirubin / Lung / Alkaline phosphatase / Superoxide Dismutase / Neutrophils / Rats / Benzoic Acid / Carrageenan / NAD / Malondialdehyde / Superoxides / Tyrosine / Biochemistry and cell biology / Alanine Transaminase / Shock / Animals / Male / Nitrates / Bilirubin / Lung / Alkaline phosphatase / Superoxide Dismutase / Neutrophils / Rats / Benzoic Acid / Carrageenan / NAD / Malondialdehyde / Superoxides / Tyrosine / Biochemistry and cell biology / Alanine Transaminase

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DNA repair mechanisms in eukaryotes: Special focus in Entamoeba histolytica and related protozoan parasites

Genetics / DNA damage / DNA repair / DNA / Humans / Animals / Cell Viability / Nucleotide Excision Repair / Information Loss / Entamoeba histolytica / Cdna Microarray / Genome sequence / Base Excision Repair / Nucleotides / Animals / Cell Viability / Nucleotide Excision Repair / Information Loss / Entamoeba histolytica / Cdna Microarray / Genome sequence / Base Excision Repair / Nucleotides

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ICSI in cases of sperm DNA damage: beneficial effect of oral antioxidant treatment

DNA damage / Human / Antioxidants / Pregnancy / Humans / vitamin C / Female / Male / Vitamin E / Incidence / Male Infertility / Human reproduction / Ascorbic Acid / Adult / Spermatozoa / Embryos / Pregnancy Outcome / DNA fragmentation / vitamin C / Female / Male / Vitamin E / Incidence / Male Infertility / Human reproduction / Ascorbic Acid / Adult / Spermatozoa / Embryos / Pregnancy Outcome / DNA fragmentation

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Organic Chemistry / Oxidative Stress / Flavonoids / DNA damage / Humans / Hydrogen Peroxide / Molecules / Plant extracts / Lymphocytes / Hydrogen Peroxide / Molecules / Plant extracts / Lymphocytes

Mitochondria / DNA damage / Apoptosis / Caspases / Glioma / Animals / Caspase / Rats / Time Factors / Antineoplastic Agents / Ligands / Biochemistry and cell biology / Animals / Caspase / Rats / Time Factors / Antineoplastic Agents / Ligands / Biochemistry and cell biology

DNA replication / DNA damage / Biological Sciences / Humans / Histones / Genomic instability / Cell cycle checkpoints / Melanocytes / Cell Proliferation / retinoblastoma protein (RB1). / Genomic instability / Cell cycle checkpoints / Melanocytes / Cell Proliferation / retinoblastoma protein (RB1).

Enzyme Inhibitors / DNA damage / DNA repair / Biological Sciences / Archaea / Sulfolobus / Hydrolysis / *Hot Temperature / Sulfolobus / Hydrolysis / *Hot Temperature

Enzyme Inhibitors / DNA damage / DNA repair / Biological Sciences / Archaea / Sulfolobus / Hydrolysis / Hot Temperature / Sulfolobus / Hydrolysis / Hot Temperature