DNA damage - Page 2

Differential mtDNA Damage Patterns in a Transgenic Mouse Model of Machado–Joseph Disease (MJD/SCA3)

Neuroscience / Cognitive Science / Molecular Neuroscience / DNA damage / Transcription Factors / Hippocampus / mtDNA / Neurodegenrative diseases / Mitochondrial DNA / Mice / Animals / Transgenic Mouse Technology / Neurosciences / Polyglutamine Disorders / Machado-Joseph Disease / Hippocampus / mtDNA / Neurodegenrative diseases / Mitochondrial DNA / Mice / Animals / Transgenic Mouse Technology / Neurosciences / Polyglutamine Disorders / Machado-Joseph Disease

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Mitochondrial DNA damage in lymphocytes: a role in immunosenescence?

Genetics / Aging / DNA damage / Cell line / Mitochondrial DNA / Humans / Female / Male / Polymerase Chain Reaction / T lymphocytes / Aged / Middle Aged / High Resolution / Experimental / Adult / Conformational Analysis / Mutation Rate / Blood cells / Control Group / Humans / Female / Male / Polymerase Chain Reaction / T lymphocytes / Aged / Middle Aged / High Resolution / Experimental / Adult / Conformational Analysis / Mutation Rate / Blood cells / Control Group

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Lactoferrin decreases LPS-induced mitochondrial dysfunction in cultured cells and in animal endotoxemia model

Immune response / Oxidative Stress / Mitochondria / DNA damage / Innate immunity / Lipopolysaccharide / Humans / Reactive Oxygen Species / Mice / Animals / Siderophores / P-glycoprotein / Iron / Innate / Hydrogen Peroxide / Mitochondrial dysfunction / Lipopolysaccharides / ENDOTOXEMIA / Epithelial cells / Monocytes / Oxidative Damage / Deferoxamine / Lipopolysaccharide / Humans / Reactive Oxygen Species / Mice / Animals / Siderophores / P-glycoprotein / Iron / Innate / Hydrogen Peroxide / Mitochondrial dysfunction / Lipopolysaccharides / ENDOTOXEMIA / Epithelial cells / Monocytes / Oxidative Damage / Deferoxamine

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Lactoferrin decreases LPS-induced mitochondrial dysfunction in cultured cells and in animal endotoxemia model

Immune response / Oxidative Stress / Mitochondria / DNA damage / Innate immunity / Lipopolysaccharide / Humans / Reactive Oxygen Species / Mice / Animals / Siderophores / P-glycoprotein / Iron / Innate / Hydrogen Peroxide / Mitochondrial dysfunction / Lipopolysaccharides / ENDOTOXEMIA / Epithelial cells / Monocytes / Oxidative Damage / Deferoxamine / Lipopolysaccharide / Humans / Reactive Oxygen Species / Mice / Animals / Siderophores / P-glycoprotein / Iron / Innate / Hydrogen Peroxide / Mitochondrial dysfunction / Lipopolysaccharides / ENDOTOXEMIA / Epithelial cells / Monocytes / Oxidative Damage / Deferoxamine

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Biomonitoring human exposure to environmental carcinogenic chemicals

Petroleum / Environmental Monitoring / DNA damage / Humans / Mutagenesis / Polycyclic aromatic hydrocarbons (PAHs) / Occupational Exposure / Nitrogen Oxides / Mutagens / Environmental Exposure / Styrene / Blood Proteins / Case Control Studies / Polycyclic aromatic hydrocarbons (PAHs) / Occupational Exposure / Nitrogen Oxides / Mutagens / Environmental Exposure / Styrene / Blood Proteins / Case Control Studies

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The protective effects of guaraná extract (Paullinia cupana) on fibroblast NIH-3T3 cells exposed to sodium nitroprusside

Oxidative Stress / DNA damage / Antioxidants / Caffeine / Mice / Nitric oxide / Animals / High Pressure Liquid Chromatography / Comet Assay / Plant extracts / Food Sciences / Human Fibroblasts / Food and Chemical Toxicology / Catechin / Theobromine / Nitric oxide / Animals / High Pressure Liquid Chromatography / Comet Assay / Plant extracts / Food Sciences / Human Fibroblasts / Food and Chemical Toxicology / Catechin / Theobromine

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Biological roles of translesion synthesis DNA polymerases in eubacteria

DNA replication / Molecular Microbiology / DNA damage / Biological Sciences / Bacteria / DNA Polymerase

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New antibodies recognizing p73: Comparison with commercial antibodies

DNA damage / Western blotting / Antibodies / Cell line / Humans / Alternative splicing / Immunoprecipitation / Western blot / Alternative Splicing / DNA binding proteins / Biochemistry and cell biology / Alternative splicing / Immunoprecipitation / Western blot / Alternative Splicing / DNA binding proteins / Biochemistry and cell biology

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PARP-1 Inhibition Increases Mitochondrial Metabolism through SIRT1 Activation

Skeletal muscle biology / Oxidative Stress / Mitochondria / DNA damage / Energy Metabolism / RNA interference / Mice / Animals / Cell Death / Phenotype / Brown Adipose Tissue / NAD / Sirtuin / Biochemistry and cell biology / RNA interference / Mice / Animals / Cell Death / Phenotype / Brown Adipose Tissue / NAD / Sirtuin / Biochemistry and cell biology

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PARP1 Inhibition Increases Mitochondrial Metabolism through SIRT1 Activation

Skeletal muscle biology / Oxidative Stress / Mitochondria / DNA damage / Energy Metabolism / RNA interference / Mice / Animals / Cell Death / Phenotype / Brown Adipose Tissue / NAD / Sirtuin / Biochemistry and cell biology / RNA interference / Mice / Animals / Cell Death / Phenotype / Brown Adipose Tissue / NAD / Sirtuin / Biochemistry and cell biology

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DNA repair efficiency in transgenic mice over expressing ribosomal protein S3

Oxidative Stress / DNA damage / DNA repair / Transgenic Mice / Protein synthesis / Humans / Mutation / Mice / Female / Animals / Male / Ribosomal proteins / Oxidative Damage / In Vitro Studies / Oxidative Dna Damage / Ribosomal Protein / Binding affinity / Humans / Mutation / Mice / Female / Animals / Male / Ribosomal proteins / Oxidative Damage / In Vitro Studies / Oxidative Dna Damage / Ribosomal Protein / Binding affinity

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Intracellular iron, but not copper, plays a critical role in hydrogen peroxide-induced DNA Damage

Calcium / DNA damage / Transition-Metal Oxides / Humans / Copper / Iron / Hydrogen Peroxide / Comet Assay / Time Factors / Chelating Agents / Oxidation-Reduction / Biochemistry and cell biology / Glucose Oxidase / Iron / Hydrogen Peroxide / Comet Assay / Time Factors / Chelating Agents / Oxidation-Reduction / Biochemistry and cell biology / Glucose Oxidase

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Mitochondrial disease in superoxide dismutase 2 mutant mice

Mitochondria / DNA damage / Multidisciplinary / Brain / Reactive Oxygen Species / Mice / Female / Animals / Male / Mitochondrial Respiratory Chain / Superoxide Dismutase / Enzyme / Oxidative phosphorylation / Carboxylic Acids / Oxidative Dna Damage / Succinate Dehydrogenase / Tissue Specificity / Mice / Female / Animals / Male / Mitochondrial Respiratory Chain / Superoxide Dismutase / Enzyme / Oxidative phosphorylation / Carboxylic Acids / Oxidative Dna Damage / Succinate Dehydrogenase / Tissue Specificity

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Genotoxic Evaluation of Mikania laevigata Extract on DNA Damage Caused by Acute Coal Dust Exposure

Nutrition and Dietetics / Coal / DNA damage / Liver / Femur / Animals / Blood / Male / Bone marrow / Comet Assay / Plant extracts / Rats / Hepatocytes / Medicinal / Group / Wistar Rats / Food Sciences / Medicinal Food / Dust / Organic Compound / Environmental Exposure / Control Group / Animals / Blood / Male / Bone marrow / Comet Assay / Plant extracts / Rats / Hepatocytes / Medicinal / Group / Wistar Rats / Food Sciences / Medicinal Food / Dust / Organic Compound / Environmental Exposure / Control Group

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Biomonitoring human exposure to environmental carcinogenic chemicals

Petroleum / Environmental Monitoring / DNA damage / Humans / Mutagenesis / Polycyclic aromatic hydrocarbons (PAHs) / Occupational Exposure / Nitrogen Oxides / Mutagens / Environmental Exposure / Styrene / Blood Proteins / Case Control Studies / Polycyclic aromatic hydrocarbons (PAHs) / Occupational Exposure / Nitrogen Oxides / Mutagens / Environmental Exposure / Styrene / Blood Proteins / Case Control Studies

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Genotoxic Evaluation of Mikania laevigata Extract on DNA Damage Caused by Acute Coal Dust Exposure

Nutrition and Dietetics / Coal / DNA damage / Liver / Femur / Animals / Blood / Male / Bone marrow / Comet Assay / Plant extracts / Rats / Hepatocytes / Medicinal / Group / Wistar Rats / Food Sciences / Medicinal Food / Dust / Organic Compound / Environmental Exposure / Control Group / Animals / Blood / Male / Bone marrow / Comet Assay / Plant extracts / Rats / Hepatocytes / Medicinal / Group / Wistar Rats / Food Sciences / Medicinal Food / Dust / Organic Compound / Environmental Exposure / Control Group

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