DNA damage

Mitochondrial DNA oxidation and manganese superoxide dismutase activity in peripheral blood mononuclear cells from type 2 diabetic patients

Diabetes / Oxidative Stress / DNA damage / Type 2 Diabetes / Mitochondrial DNA / Humans / Insulin / Female / Male / Superoxide Dismutase / Clinical Sciences / Aged / Middle Aged / Oral Hypoglycemic Agents / Combination drug therapy / Type 2 Diabetes Mellitus / Reference Values / Humans / Insulin / Female / Male / Superoxide Dismutase / Clinical Sciences / Aged / Middle Aged / Oral Hypoglycemic Agents / Combination drug therapy / Type 2 Diabetes Mellitus / Reference Values

Human Glutathione 5\"Transferase Deficiency as a Marker of Susceptibility to Epoxide-induced Cytogenetic Damage1

Genetics / DNA damage / Lung Cancer / Glutathione / Enzyme / Peripheral blood lymphocyte / Genetic Polymorphism / High Sensitivity / Cancer Risk / Peripheral blood lymphocyte / Genetic Polymorphism / High Sensitivity / Cancer Risk

La restricción de metionina en la dieta disminuye el estrés oxidativo en mitocondrias de corazón

DNA damage / Free Radical / Mitochondrial DNA / Oxidative Damage / Caloric Restriction

DNA Integrity Is Compromised in Protamine-Deficient Human Sperm

Andrology / DNA damage / Humans / Male / Male Infertility / Chromatin / Clinical Sciences / Reproducibility of Results / Spermatozoa / DNA fragmentation / Chromatin / Clinical Sciences / Reproducibility of Results / Spermatozoa / DNA fragmentation

ICSI in cases of sperm DNA damage: beneficial effect of oral antioxidant treatment

DNA damage / Human / Antioxidants / Pregnancy / Humans / vitamin C / Female / Male / Vitamin E / Incidence / Male Infertility / Human reproduction / Ascorbic Acid / Adult / Spermatozoa / Embryos / Pregnancy Outcome / DNA fragmentation / vitamin C / Female / Male / Vitamin E / Incidence / Male Infertility / Human reproduction / Ascorbic Acid / Adult / Spermatozoa / Embryos / Pregnancy Outcome / DNA fragmentation

Mcl1p Is a Polymerase   Replication Accessory Factor Important for S-Phase DNA Damage Survival

DNA damage / Biological Sciences / DNA / Mutation / Temperature / Sucrose / Phenotype / Chromatin / Schizosaccharomyces Pombe / Genotype / Glutathione Transferase / Two-Dimensional Gel Electrophoresis / Cell Cycle Proteins / Protein Binding / Eukaryotic Cell / Sucrose / Phenotype / Chromatin / Schizosaccharomyces Pombe / Genotype / Glutathione Transferase / Two-Dimensional Gel Electrophoresis / Cell Cycle Proteins / Protein Binding / Eukaryotic Cell

Translational Control of TOP2A Influences Doxorubicin Efficacy

Cellular Biology / DNA damage / Biological Sciences / DNA / RNA interference / Molecular and cellular biology / Humans / microRNAs / Doxorubicin / RNA-binding proteins / HeLa cells / DNA binding proteins / Protein Biosynthesis / Gene Expression Regulation / Molecular and cellular biology / Humans / microRNAs / Doxorubicin / RNA-binding proteins / HeLa cells / DNA binding proteins / Protein Biosynthesis / Gene Expression Regulation

Donor cornea transfer from Optisol GS to organ culture storage: a two-step procedure to increase donor tissue lifespan

Stem Cells / Oxidative Stress / Cornea / Cryopreservation / DNA damage / Humans / Female / Male / Differentiation / Organ Preservation / Lipid peroxidation / Clinical Sciences / Comet Assay / Middle Aged / Optometry and Ophthalmology / Time Factors / Organ Culture / Biological markers / Cell Proliferation / Neurosciences / Enzyme Linked Immunosorbent Assay / Organ Preservation Solutions / Humans / Female / Male / Differentiation / Organ Preservation / Lipid peroxidation / Clinical Sciences / Comet Assay / Middle Aged / Optometry and Ophthalmology / Time Factors / Organ Culture / Biological markers / Cell Proliferation / Neurosciences / Enzyme Linked Immunosorbent Assay / Organ Preservation Solutions

Sequential assembly of translesion DNA polymerases at UV-induced DNA damage sites

Molecular Biology / DNA replication / DNA damage / Biological Sciences / Humans / Cell nucleus / DNA binding proteins / Cell nucleus / DNA binding proteins

Rad21-cohesin haploinsufficiency impedes DNA repair and enhances gastrointestinal radiosensitivity in mice

Stem Cells / DNA damage / DNA repair / Stem Cell / Multidisciplinary / Mitosis / Cell line / Mice / Animals / Bone marrow / PLoS one / Epithelial cells / Radiation Dose / DNA damage response / Gene Targeting / Chromosome segregation / Gastrointestinal Tract / Homologous Recombination / Human Fibroblasts / Cell Cycle Proteins / Cell Survival / Radiation Tolerance / Whole Body / Functional Status / Bone Marrow Cells / Mitomycin / Mitosis / Cell line / Mice / Animals / Bone marrow / PLoS one / Epithelial cells / Radiation Dose / DNA damage response / Gene Targeting / Chromosome segregation / Gastrointestinal Tract / Homologous Recombination / Human Fibroblasts / Cell Cycle Proteins / Cell Survival / Radiation Tolerance / Whole Body / Functional Status / Bone Marrow Cells / Mitomycin

Molecular epidemiology studies of carcinogenic environmental pollutants

Genetics / Polymorphism / Environmental Monitoring / Air pollution / DNA damage / DNA repair / Environmental Pollution / Czech Republic / Molecular Epidemiology / Humans / Mutation / Polycyclic Aromatic Hydrocarbon / Carcinogens / Enzyme / Reviews / Comet Assay / Polycyclic aromatic hydrocarbons (PAHs) / Fluorescent In-Situ Hybridisation / Neoplasms / Particulate Matter / Biological markers / Environmental Pollutants / Oxidative Dna Damage / Genetic Susceptibility / Cancer Risk / Organic Compound / Environmental Exposure / DNA repair / Environmental Pollution / Czech Republic / Molecular Epidemiology / Humans / Mutation / Polycyclic Aromatic Hydrocarbon / Carcinogens / Enzyme / Reviews / Comet Assay / Polycyclic aromatic hydrocarbons (PAHs) / Fluorescent In-Situ Hybridisation / Neoplasms / Particulate Matter / Biological markers / Environmental Pollutants / Oxidative Dna Damage / Genetic Susceptibility / Cancer Risk / Organic Compound / Environmental Exposure

Depressive symptoms and oxidative DNA damage in Japanese municipal employees

Psychiatry / Depression / Japanese / Japan / DNA damage / Humans / Female / Male / Aged / Prevalence / Middle Aged / Adult / Sex Factors / Humans / Female / Male / Aged / Prevalence / Middle Aged / Adult / Sex Factors

Transient OGG1, APE1, PARP1 and Polβ expression in an Alzheimer\'s disease mouse model

Oxidative Stress / DNA damage / DNA repair / Brain / Humans / Mice / Animals / Clinical Sciences / Alzheimer Disease / Mice / Animals / Clinical Sciences / Alzheimer Disease

Tetraciclinas, sulfamidas y metronidazol

Medical Microbiology / DNA damage / Protein synthesis / Humans / Anaerobic Bacteria / Spectrum / Anti-Bacterial Agents / World Health Organization / Bacterial infections / Parasitic Diseases / Metronidazole / Bactericidal Activity / Molecular Structure / Spectrum / Anti-Bacterial Agents / World Health Organization / Bacterial infections / Parasitic Diseases / Metronidazole / Bactericidal Activity / Molecular Structure

Preclinical Evaluation of a Potent Novel DNA-Dependent Protein Kinase Inhibitor NU7441

Cancer / Flow Cytometry / Cell Cycle / DNA damage / Cell line / Humans / Mice / Female / Animals / Phosphorylation / Histones / Colon cancer / Protein Kinase / Ionizing Radiation / Cell Cycle Arrest / Chromones / Tumor Growth / Therapeutic Use / Protein Kinase Inhibitors / Humans / Mice / Female / Animals / Phosphorylation / Histones / Colon cancer / Protein Kinase / Ionizing Radiation / Cell Cycle Arrest / Chromones / Tumor Growth / Therapeutic Use / Protein Kinase Inhibitors

Loss of dE2F Compromises Mitochondrial Function

Cell Cycle / Drosophila melanogaster / Mitochondria / Gamma Rays / DNA damage / Apoptosis / Western blotting / Biological Sciences / Humans / Animals / Osteosarcoma / Phenotype / Fluorescent Antibody Technique / Chromatin Immunoprecipitation / Cell Proliferation / Apoptosis / Western blotting / Biological Sciences / Humans / Animals / Osteosarcoma / Phenotype / Fluorescent Antibody Technique / Chromatin Immunoprecipitation / Cell Proliferation
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