Biotransformation

Preclinical drug metabolism and pharmacokinetic evaluation of GW844520, a novel anti-malarial mitochondrial electron transport inhibitor

Metabolism / Evaluation / Pharmacokinetics / Drug metabolism / Mitochondria / Dogs / Cell line / Transport / Humans / Permeability / Mice / Pharmaceutical Sciences / Female / Animals / Male / Electron Transport / Bioavailability / Clearance / Rats / Hepatocytes / Antimalarials / Biotransformation / Macaca fascicularis / Protein Binding / Dogs / Cell line / Transport / Humans / Permeability / Mice / Pharmaceutical Sciences / Female / Animals / Male / Electron Transport / Bioavailability / Clearance / Rats / Hepatocytes / Antimalarials / Biotransformation / Macaca fascicularis / Protein Binding

EVALUACIÓN DE LA BIOTRANSFORMACIÓN DE GERANIOL Y (R)-(+)-a-PINENO EMPLEANDO CÉLULAS DE Rhodococcus opacus DSM 44313 EVALUATION OF THE BIOTRANSFORMATION OF GERANIOL AND (R)-(+)-a-PINENE USING CELL OF Rhodococcus opacus DSM 44313

J. R. R. Tolkien / Biotransformation / Geraniol

Microbial Conversion of Partheniol by Calonectria decora

Fungi / Magnetic Resonance Spectroscopy / Bacteria / Sesquiterpenes / Fermentation / Liquid Chromatography / Electrospray Ionization Mass Spectrometry / Biotransformation / Gas Chromatography/mass Spectrometry / Molecular Conformation / Molecular Structure / Liquid Chromatography / Electrospray Ionization Mass Spectrometry / Biotransformation / Gas Chromatography/mass Spectrometry / Molecular Conformation / Molecular Structure

Clinical Pharmacokinetics and Pharmacodynamics of Desloratadine, Fexofenadine and Levocetirizine: A Comparative Review

Nonlinear dynamics / Membrane Proteins / Drug interactions / Therapeutic drug monitoring / Stroke / Pregnancy / Humans / Autoimmune diseases / Clinical Pharmacokinetics / Pharmacogenetics / Female / Organ Transplantation / Intestinal absorption / Myocardial Infarction / Adult / Isoenzymes / Biotransformation / Pyrazoles / Area Under Curve / Pregnancy / Humans / Autoimmune diseases / Clinical Pharmacokinetics / Pharmacogenetics / Female / Organ Transplantation / Intestinal absorption / Myocardial Infarction / Adult / Isoenzymes / Biotransformation / Pyrazoles / Area Under Curve

Myeloperoxidase - 463A variant reduces benzo(a)pyrene diol epoxide DNA adducts in skin of coal tar treated patients

Adolescent / DNA / Peroxidase / Humans / Female / Male / Skin / Middle Aged / Carcinogenesis / Adult / Biotransformation / Coal Tar / Mutagens / Myeloperoxidase / Male / Skin / Middle Aged / Carcinogenesis / Adult / Biotransformation / Coal Tar / Mutagens / Myeloperoxidase

Pharmacokinetic evaluation of indomethacin ethyl ester-loaded nanoencapsules

Pharmaceutics / Prodrugs / Animals / Male / Nanocapsules / Rats / Biotransformation / Wistar Rats / Drug Compounding / Indomethacin / Rats / Biotransformation / Wistar Rats / Drug Compounding / Indomethacin

Plasmid-Encoded Degradation ofp-Nitrophenol byPseudomonas cepacia

Mutagenesis / Nitrogen / Zinc / Gas Chromatography / Plasmids / Biotransformation / Burkholderia Cepacia / Thin Layer Chromatography / Biochemistry and cell biology / Mitomycin / Parathion / Biotransformation / Burkholderia Cepacia / Thin Layer Chromatography / Biochemistry and cell biology / Mitomycin / Parathion

Trophic Distribution of Cd, Pb, and Zn in a Food Web from Altata-Ensenada del Pabellón Subtropical Lagoon, SE Gulf of California

Multidisciplinary / Mexico / Heavy metals / Food web / Birds / Animals / Fishes / Trophic Level / Ecosystem / Fresh water / Biotransformation / Shellfish / Gulf of California / MEXICO / Trophic Interaction / Food Chain / Environmental Exposure / Penaeidae / Animals / Fishes / Trophic Level / Ecosystem / Fresh water / Biotransformation / Shellfish / Gulf of California / MEXICO / Trophic Interaction / Food Chain / Environmental Exposure / Penaeidae

Colorectal Cancer-Specific Cytochrome P450 2W1: Intracellular Localization, Glycosylation, and Catalytic Activity

Molecular Pharmacology / Colorectal cancer / Humans / Glycosylation / Caco-2 cells / Biotransformation / Asparagine / Neurosciences / Catalytic Activity / Biotransformation / Asparagine / Neurosciences / Catalytic Activity

Colorectal Cancer-Specific Cytochrome P450 2W1: Intracellular Localization, Glycosylation, and Catalytic Activity

Molecular Pharmacology / Colorectal cancer / Humans / Glycosylation / Caco-2 cells / Biotransformation / Asparagine / Neurosciences / Catalytic Activity / Biotransformation / Asparagine / Neurosciences / Catalytic Activity

Comparison of two compartmental models for describing ranitidine\'s plasmatic profiles

Humans / Animals / Male / Statistical Significance / High Pressure Liquid Chromatography / Intestinal absorption / Rats / Adult / Biotransformation / Gastrointestinal Tract / Wistar Rats / Pharmacological / Statistical Test / Ranitidine / Biological Availability / Area Under the Curve / Area Under Curve / Bile / Intestinal absorption / Rats / Adult / Biotransformation / Gastrointestinal Tract / Wistar Rats / Pharmacological / Statistical Test / Ranitidine / Biological Availability / Area Under the Curve / Area Under Curve / Bile

Preclinical drug metabolism and pharmacokinetic evaluation of GW844520, a novel anti-malarial mitochondrial electron transport inhibitor

Drug metabolism / Dogs / Cell line / Humans / Mice / Pharmaceutical Sciences / Female / Animals / Male / Electron Transport / Rats / Hepatocytes / Antimalarials / Biotransformation / Macaca fascicularis / Protein Binding / Pharmaceutical Sciences / Female / Animals / Male / Electron Transport / Rats / Hepatocytes / Antimalarials / Biotransformation / Macaca fascicularis / Protein Binding

Design, synthesis and melatoninergic potency of new N-acyl 8,9-dihydro-4-methoxy-7H-2-benzo[de]quinolinalkanamines

Organic Chemistry / Magnetic Resonance Spectroscopy / Melatonin / Bioorganic Chemistry / Humans / Mice / Animals / Drug Design / Xenopus laevis / Biotransformation / Quinolines / Melanophores / Binding Site / Bioorganic / Mice / Animals / Drug Design / Xenopus laevis / Biotransformation / Quinolines / Melanophores / Binding Site / Bioorganic

Boronic acids—A novel class of bacterial mutagen

Environmental Biotechnology / Humans / Mutation / Escherichia coli / Animals / Salmonella Typhimurium / Boronic Acids / Biotransformation / Mechanism of action / Mutagens / Salmonella Typhimurium / Boronic Acids / Biotransformation / Mechanism of action / Mutagens

Enhancement of a pentacyclic tyrosine kinase inhibitor production in Cladosporium cf. cladosporioides by Cladosporol

Enzyme Inhibitors / Multidisciplinary / Applied Microbiology and Biotechnology / Tyrosine Kinase Inhibitor / Biotransformation / Chromones / Molecular Structure / Cladosporium / Chromones / Molecular Structure / Cladosporium

Enhancement of a pentacyclic tyrosine kinase inhibitor production in Cladosporium cf. cladosporioides by Cladosporol

Enzyme Inhibitors / Multidisciplinary / Applied Microbiology and Biotechnology / Tyrosine Kinase Inhibitor / Biotransformation / Chromones / Molecular Structure / Cladosporium / Chromones / Molecular Structure / Cladosporium

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