Tubulin

The Synergistic Combination of the Farnesyl Transferase Inhibitor Lonafarnib and Paclitaxel Enhances Tubulin Acetylation and Requires a Functional Tubulin Deacetylase

Cancer / Mitosis / Cell line / Humans / Low Dose / Mice / Animals / HIstone Deacetylase / Cell Death / Paclitaxel / Microtubules / Acetylation / Pyridines / Tubulin / Histone deacetylase inhibitors / Histone deacetylases / Piperidines / Synergistic effect / Mice / Animals / HIstone Deacetylase / Cell Death / Paclitaxel / Microtubules / Acetylation / Pyridines / Tubulin / Histone deacetylase inhibitors / Histone deacetylases / Piperidines / Synergistic effect

Paclitaxel ameliorates renal fibrosis

Drug development / Drug Design / Paclitaxel / Tubulin

Target proteins of ganoderic acid DM provides clues to various pharmacological mechanisms

Kinetics / Humans / Male / Cell Fractionation / Ganoderma / High Pressure Liquid Chromatography / Tubulin / Structure activity Relationship / Protein Binding / Cell Survival / Antineoplastic Agents / Vinblastine / Triterpenes / High Pressure Liquid Chromatography / Tubulin / Structure activity Relationship / Protein Binding / Cell Survival / Antineoplastic Agents / Vinblastine / Triterpenes

Human fetal cortical and striatal neural stem cells generate region-specific neurons in vitro and differentiate extensively to neurons after intrastriatal transplantation in neonatal rats

Neuroscience / Psychology / Stem Cells / Immunohistochemistry / Stem Cell Transplantation / Cell Differentiation / Humans / Animals / Neurons / Rats / Time Factors / Tubulin / Fetus / Cell Proliferation / Somatic Cell Count / Neurosciences / Vimentin / Glutamic Acid / Gamma-Aminobutyric Acid / Cell Differentiation / Humans / Animals / Neurons / Rats / Time Factors / Tubulin / Fetus / Cell Proliferation / Somatic Cell Count / Neurosciences / Vimentin / Glutamic Acid / Gamma-Aminobutyric Acid

Combined extrinsic and intrinsic manipulations exert complementary neuronal enrichment in embryonic rat neural precursor cultures: An in vitro and in vivo analysis

Zoology / Stem Cell Transplantation / Cell Differentiation / Animals / Spinal Cord / Male / The / Medical Physiology / Fibroblast Growth Factor / Rats / Tubulin / Biological markers / Cell Proliferation / Neurosciences / Interneurons / Gamma-Aminobutyric Acid / Male / The / Medical Physiology / Fibroblast Growth Factor / Rats / Tubulin / Biological markers / Cell Proliferation / Neurosciences / Interneurons / Gamma-Aminobutyric Acid

Parthenolide Inhibits Tubulin Carboxypeptidase Activity

Principal Component Analysis / Cancer / Drug interactions / Cell Division / Humans / NF-kappa B / Paclitaxel / Sesquiterpenes / HeLa cells / Tubulin / Carboxypeptidases / Structure activity Relationship / Tumor Progression / NF-kappa B / Paclitaxel / Sesquiterpenes / HeLa cells / Tubulin / Carboxypeptidases / Structure activity Relationship / Tumor Progression

Direct measurement of energy fluxes from mitochondria into cytoplasm in permeabilized cardiac cells in situ: some evidence for mitochondrial interactosome

Bioenergetics / Energy Metabolism / Pyruvate Kinase / Animals / Creatine Kinase / High Pressure Liquid Chromatography / Rats / Tubulin / Adenine Nucleotide Translocase / Energy Flux / Mitochondrial Membrane Potential / Oxygen Consumption / Creatinine / Biochemistry and cell biology / Adenosine Triphosphate / High Pressure Liquid Chromatography / Rats / Tubulin / Adenine Nucleotide Translocase / Energy Flux / Mitochondrial Membrane Potential / Oxygen Consumption / Creatinine / Biochemistry and cell biology / Adenosine Triphosphate

Ectopic A-lattice seams destabilize microtubules

Multidisciplinary / Animals / Microtubules / Kinesin / Rats / Guanosine Triphosphate / Surface Properties / Tubulin / Molecular Conformation / Sus Scrofa / Nature Communications / Protein Transport / Guanosine Triphosphate / Surface Properties / Tubulin / Molecular Conformation / Sus Scrofa / Nature Communications / Protein Transport

Glutathione S-Transferase Omega 1 Activity Is Sufficient to Suppress Neurodegeneration in a Drosophila Model of Parkinson Disease

Drosophila melanogaster / Oxidative Stress / Biological Chemistry / Signal Transduction / Biological Sciences / Animals / Male / Unfolded Protein Response / Paraquat / Phenotype / Herbicides / CHEMICAL SCIENCES / Tubulin / Glutathione Transferase / Animals / Male / Unfolded Protein Response / Paraquat / Phenotype / Herbicides / CHEMICAL SCIENCES / Tubulin / Glutathione Transferase

The Synergistic Combination of the Farnesyl Transferase Inhibitor Lonafarnib and Paclitaxel Enhances Tubulin Acetylation and Requires a Functional Tubulin Deacetylase

Cancer / Mitosis / Cell line / Humans / Low Dose / Mice / Animals / HIstone Deacetylase / Cell Death / Paclitaxel / Microtubules / Acetylation / Pyridines / Tubulin / Histone deacetylase inhibitors / Histone deacetylases / Piperidines / Synergistic effect / Mice / Animals / HIstone Deacetylase / Cell Death / Paclitaxel / Microtubules / Acetylation / Pyridines / Tubulin / Histone deacetylase inhibitors / Histone deacetylases / Piperidines / Synergistic effect

MAP Kinase Kinase 6 -p38 MAP Kinase Signaling Cascade Regulates Cyclooxygenase-2 Expression in Cardiac Myocytes In Vitro and In Vivo

Enzyme Inhibitors / Gene expression / Transgenic Mice / Protein synthesis / Animals / Phosphorylation / Clinical Sciences / mRna expression levels / Rats / Isoenzymes / Pyridines / Circulation / Tubulin / Imidazoles / Recombinant Protein / MAP Kinase / Heart Ventricles / Prostaglandin E2 / Interleukin / Phosphorylation / Clinical Sciences / mRna expression levels / Rats / Isoenzymes / Pyridines / Circulation / Tubulin / Imidazoles / Recombinant Protein / MAP Kinase / Heart Ventricles / Prostaglandin E2 / Interleukin

MAP Kinase Kinase 6-p38 MAP Kinase Signaling Cascade Regulates Cyclooxygenase-2 Expression in Cardiac Myocytes In Vitro and In Vivo

Enzyme Inhibitors / Gene expression / Transgenic Mice / Protein synthesis / Animals / Phosphorylation / Clinical Sciences / mRna expression levels / Rats / Isoenzymes / Pyridines / Circulation / Tubulin / Imidazoles / Recombinant Protein / MAP Kinase / Heart Ventricles / Prostaglandin E2 / Interleukin / Phosphorylation / Clinical Sciences / mRna expression levels / Rats / Isoenzymes / Pyridines / Circulation / Tubulin / Imidazoles / Recombinant Protein / MAP Kinase / Heart Ventricles / Prostaglandin E2 / Interleukin

An Essential Quality Control Mechanism at the Eukaryotic Basal Body Prior to Intraflagellar Transport

Quality Control / Phylogeny / Cell line / Humans / Retinitis pigmentosa / Animals / Flagella / Traffic / Trypanosoma brucei brucei / Tubulin / Biochemistry and cell biology / Dimerization / Animals / Flagella / Traffic / Trypanosoma brucei brucei / Tubulin / Biochemistry and cell biology / Dimerization

New tubulins in protozoal parasites

Biological Sciences / Animals / Burns / Current / Trypanosoma brucei brucei / Tubulin / Protozoan Proteins / Amino Acid Sequence / Leishmania Major / Tubulin / Protozoan Proteins / Amino Acid Sequence / Leishmania Major

The Synergistic Combination of the Farnesyl Transferase Inhibitor Lonafarnib and Paclitaxel Enhances Tubulin Acetylation and Requires a Functional Tubulin Deacetylase

Cancer / Mitosis / Cell line / Humans / Low Dose / Mice / Animals / HIstone Deacetylase / Cell Death / Paclitaxel / Microtubules / Acetylation / Pyridines / Tubulin / Histone deacetylase inhibitors / Histone deacetylases / Piperidines / Synergistic effect / Mice / Animals / HIstone Deacetylase / Cell Death / Paclitaxel / Microtubules / Acetylation / Pyridines / Tubulin / Histone deacetylase inhibitors / Histone deacetylases / Piperidines / Synergistic effect

Direct measurement of energy fluxes from mitochondria into cytoplasm in permeabilized cardiac cells in situ: some evidence for mitochondrial interactosome

Mitochondria / Bioenergetics / Energy Metabolism / Pyruvate Kinase / Animals / Respiration / Creatine Kinase / High Pressure Liquid Chromatography / Rats / Tubulin / Adenine Nucleotide Translocase / Energy Flux / Mitochondrial Membrane Potential / Oxygen Consumption / Creatinine / Biochemistry and cell biology / Adenosine Triphosphate / Phosphocreatine / Respiration / Creatine Kinase / High Pressure Liquid Chromatography / Rats / Tubulin / Adenine Nucleotide Translocase / Energy Flux / Mitochondrial Membrane Potential / Oxygen Consumption / Creatinine / Biochemistry and cell biology / Adenosine Triphosphate / Phosphocreatine
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