Signal Transduction

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

Genomics / Cancer / Adolescent / DNA repair / Gene expression / Multidisciplinary / Nature / Signal Transduction / Humans / Mutation / Glioblastoma / Female / Male / DNA methylation / Gene Dosage / Aged / Middle Aged / Human Genome / Adult / Retrospective Studies / Large Scale / DNA Copy Number / Multi Dimensional / Pilot project / Brain Neoplasms / Multidisciplinary / Nature / Signal Transduction / Humans / Mutation / Glioblastoma / Female / Male / DNA methylation / Gene Dosage / Aged / Middle Aged / Human Genome / Adult / Retrospective Studies / Large Scale / DNA Copy Number / Multi Dimensional / Pilot project / Brain Neoplasms

Bradykinin receptor 1 activation exacerbates experimental focal and segmental glomerulosclerosis

Membrane Proteins / Macrophages / Signal Transduction / Glomerular Diseases / Psicología / Kidney / Mice / Animals / End Stage Renal Failure / Male / Heme Oxygenase / Clinical Sciences / Doxorubicin / Mouse Model / Time Factors / Body Weight / Albuminuria / Renal Fibrosis / Podocytes / Renal Dysfunction / Gene Expression Regulation / Matrix Metalloproteinase / Bradykinin / Focal Segmental Glomerulosclerosis / Kidney / Mice / Animals / End Stage Renal Failure / Male / Heme Oxygenase / Clinical Sciences / Doxorubicin / Mouse Model / Time Factors / Body Weight / Albuminuria / Renal Fibrosis / Podocytes / Renal Dysfunction / Gene Expression Regulation / Matrix Metalloproteinase / Bradykinin / Focal Segmental Glomerulosclerosis

Ventral midbrain glia express region-specific transcription factors and regulate dopaminergic neurogenesis through Wnt-5a secretion

Cognitive Science / Transcription Factors / Signal Transduction / Neural Development / Dopamine / Antibodies / Cell Differentiation / Molecular and cellular biology / Cerebral Cortex / Animals / Astrocyte / Glial Cell / Transcription Factor / Tyrosine Hydroxylase / Rats / Radial Glia / Cellular and Molecular Neuroscience / DNA binding proteins / Neurosciences / Antibodies / Cell Differentiation / Molecular and cellular biology / Cerebral Cortex / Animals / Astrocyte / Glial Cell / Transcription Factor / Tyrosine Hydroxylase / Rats / Radial Glia / Cellular and Molecular Neuroscience / DNA binding proteins / Neurosciences

Murine central and peripheral nervous system transcriptomes: Comparative gene expression

Genetics / Cognitive Science / Computational Biology / Gene expression / Real-time RT-PCR / Signal Transduction / Brain / Mice / Animals / Spinal Cord / Peripheral Nervous System / Male / Potassium / Synaptic Transmission / Sodium channel / Nervous System / G protein / Cell Surface Markers / Neurosciences / Organic Acid / Gene expression profiling / Signal Transduction / Brain / Mice / Animals / Spinal Cord / Peripheral Nervous System / Male / Potassium / Synaptic Transmission / Sodium channel / Nervous System / G protein / Cell Surface Markers / Neurosciences / Organic Acid / Gene expression profiling

Upregulation of MG53 Induces Diabetic Cardiomyopathy via Transcriptional Activation of PPAR-α

Signal Transduction / Insulin Resistance / Mice / Animals / Male / Lipid metabolism / Clinical Sciences / Rats / Public health systems and services research / Circulation / Lipid metabolism / Clinical Sciences / Rats / Public health systems and services research / Circulation

PDGF signal transduction inhibition ameliorates experimental mesangial proliferative glomerulonephritis1

Enzyme Inhibitors / Extracellular Matrix / Cell Division / Signal Transduction / Cell line / Smooth muscle / Kidney / Collagen / Animals / Male / Fibroblast Growth Factor / Clinical Sciences / Rats / Wistar Rats / Cell Proliferation / Growth Factor / Renal disease / Benzamides / Receptor Tyrosine Kinase / Smooth muscle / Kidney / Collagen / Animals / Male / Fibroblast Growth Factor / Clinical Sciences / Rats / Wistar Rats / Cell Proliferation / Growth Factor / Renal disease / Benzamides / Receptor Tyrosine Kinase

Mineralocorticoid Receptor Antagonism in Experimental Atherosclerosis

Signal Transduction / Nitric oxide / Animals / Male / New Zealand / Vascular endothelium / Acetylcholine / Real Time / NADPH oxidase / Clinical Sciences / Endothelial Function / Public health systems and services research / Circulation / Multienzyme complexes / Rabbits / Angiotensin II / Aorta / Mineralocorticoid Receptor / Superoxides / Radioimmunoassay / Vascular endothelium / Acetylcholine / Real Time / NADPH oxidase / Clinical Sciences / Endothelial Function / Public health systems and services research / Circulation / Multienzyme complexes / Rabbits / Angiotensin II / Aorta / Mineralocorticoid Receptor / Superoxides / Radioimmunoassay

Identification and characterization of endoglucanases for fungicidal activity in Anabaena laxa (Cyanobacteria)

Electrophysiology / Immune response / Kinetics / MicroRNA / Mass Spectrometry / Flow Cytometry / Calcium / Biological Chemistry / Fluorescent Dyes and Reagents / RNA silencing / Dendritic Cells / Signal Transduction / Polyamines / Biological Sciences / RNA interference / Dogs / Plant Genome Project / Cell line / Environmental Sciences / Humans / Sequence alignment / Protein Kinases / Applied / Applied Phycology / Animals / Monoclonal Antibodies / Oryza Sativa / Peptides / Dendritic cell / Chemotaxis / Nucleic Acids / Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis / Small RNA / Mitogen Activated Protein Kinase / CHEMICAL SCIENCES / Molecular cloning / Rats / Experimental Medicine / Genomic Library / Amino Acid Profile / SIGNAL PEPTIDE / Amino Acid Sequence / Benzoxazoles / Cell Wall / Open Reading Frame / Recombinant Proteins / Protein Binding / Bacterial Infection / Ligands / Cyclic nucleotide / Protein Kinase Inhibitors / cDNA library / Nucleotides / Gene Expression Regulation / Adenosine Triphosphate / Intracellular Calcium / Tissue Specificity / Host Defense / Flow Cytometry / Calcium / Biological Chemistry / Fluorescent Dyes and Reagents / RNA silencing / Dendritic Cells / Signal Transduction / Polyamines / Biological Sciences / RNA interference / Dogs / Plant Genome Project / Cell line / Environmental Sciences / Humans / Sequence alignment / Protein Kinases / Applied / Applied Phycology / Animals / Monoclonal Antibodies / Oryza Sativa / Peptides / Dendritic cell / Chemotaxis / Nucleic Acids / Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis / Small RNA / Mitogen Activated Protein Kinase / CHEMICAL SCIENCES / Molecular cloning / Rats / Experimental Medicine / Genomic Library / Amino Acid Profile / SIGNAL PEPTIDE / Amino Acid Sequence / Benzoxazoles / Cell Wall / Open Reading Frame / Recombinant Proteins / Protein Binding / Bacterial Infection / Ligands / Cyclic nucleotide / Protein Kinase Inhibitors / cDNA library / Nucleotides / Gene Expression Regulation / Adenosine Triphosphate / Intracellular Calcium / Tissue Specificity / Host Defense

A Lymphotoxin-Driven Pathway to Hepatocellular Carcinoma

Hospitality Management / Signal Transduction / Humans / Liver / Mice / Animals / Male / Hepatocellular Carcinoma / Hepatocytes / Tumor necrosis factor-alpha / Cancer Cell / Lymphocytes / Chemokines / Recombinant Proteins / Ligands / Neurosciences / Case Control Studies / Animals / Male / Hepatocellular Carcinoma / Hepatocytes / Tumor necrosis factor-alpha / Cancer Cell / Lymphocytes / Chemokines / Recombinant Proteins / Ligands / Neurosciences / Case Control Studies

Cytotoxic immunological synapses

Immunology / Apoptosis / Signal Transduction / Humans / Natural Killer cells / Animals

Compartmentalization of NO signaling cascade in skeletal muscles

Electron Microscopy / Skeletal muscle biology / Immunohistochemistry / Signal Transduction / Nitric oxide / Animals / Polymerase Chain Reaction / Biochemical / Enzyme / Phosphodiesterase Inhibitors / Skeletal Muscle / Rats / Nitric Oxide Synthase / Base Sequence / Biochemistry and cell biology / Sarcoplasmic reticulum / Animals / Polymerase Chain Reaction / Biochemical / Enzyme / Phosphodiesterase Inhibitors / Skeletal Muscle / Rats / Nitric Oxide Synthase / Base Sequence / Biochemistry and cell biology / Sarcoplasmic reticulum

Ceramide kinase deficiency impairs microendothelial cell angiogenesis in vitro

Enzyme Inhibitors / Signal Transduction / Microvascular Physiology / Capillaries / Mice / Animals / Vascular endothelium / Fibroblast Growth Factor / Clinical Sciences / Endothelial cell / Dermis / Cell Proliferation / Tumor Necrosis Factor–α (TNF) / Sphingosine 1-phosphate / Ceramides / Vascular Endothelial Growth Factor / Animals / Vascular endothelium / Fibroblast Growth Factor / Clinical Sciences / Endothelial cell / Dermis / Cell Proliferation / Tumor Necrosis Factor–α (TNF) / Sphingosine 1-phosphate / Ceramides / Vascular Endothelial Growth Factor

A microRNA-1280/JAG2 network comprises a novel biological target in high-risk medulloblastoma

Computational Biology / Membrane Proteins / Signal Transduction / RNA interference / Humans / Medulloblastoma / Cell Death / microRNAs / Neoplasm Invasiveness / Prognosis / Transfection / Cell Proliferation / Antineoplastic Agents / Molecular Targeted Therapy / RNAi Therapeutics / Gene expression profiling / Medulloblastoma / Cell Death / microRNAs / Neoplasm Invasiveness / Prognosis / Transfection / Cell Proliferation / Antineoplastic Agents / Molecular Targeted Therapy / RNAi Therapeutics / Gene expression profiling

Mdm2 haplo-insufficiency profoundly inhibits Myc-induced lymphomagenesis

Biochemistry / Genetics / Neuroscience / Immunology / Structural Biology / Structure / RNA / Plant Biology / Cell Cycle / Cell Biology / Apoptosis / Signal Transduction / Biological Sciences / Longevity / Mice / Animals / Cell Signalling / Proteins / Diffuse Large B-Cell Lymphoma / B Lymphocytes / Cell Survival / Structure / RNA / Plant Biology / Cell Cycle / Cell Biology / Apoptosis / Signal Transduction / Biological Sciences / Longevity / Mice / Animals / Cell Signalling / Proteins / Diffuse Large B-Cell Lymphoma / B Lymphocytes / Cell Survival

GCC signaling in colorectal cancer: Is colorectal cancer a paracrine deficiency syndrome?

Colorectal cancer / Signal Transduction / Humans / Mice / Animals / Natriuretic Peptides / Drug Delivery Systems / Hormone Replacement Therapy / Guanylate Cyclase / Colorectal Neoplasms / Natriuretic Peptides / Drug Delivery Systems / Hormone Replacement Therapy / Guanylate Cyclase / Colorectal Neoplasms
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