Signal Transduction

MicroRNA-132 Potentiates Cholinergic Anti-Inflammatory Signaling by Targeting Acetylcholinesterase

Immunology / MicroRNA / Inflammation / Macrophages / Signal Transduction / Cell line / Humans / Mice / Immunity / Female / Animals / Acetylcholinesterase / Acetylcholine / microRNAs / Lipopolysaccharides / Base Sequence / Oligonucleotides / Bone Marrow Cells / Down-Regulation / Cell line / Humans / Mice / Immunity / Female / Animals / Acetylcholinesterase / Acetylcholine / microRNAs / Lipopolysaccharides / Base Sequence / Oligonucleotides / Bone Marrow Cells / Down-Regulation

Antimicrobial peptides and pregnancy

Physiology / Reproduction / Inflammation / Signal Transduction / Pregnancy / Humans / Female / Animals / Risk factors / Clinical Sciences / Antimicrobial Cationic Peptides / Risk Factors / Humans / Female / Animals / Risk factors / Clinical Sciences / Antimicrobial Cationic Peptides / Risk Factors

Leptin induces, via ERK1/ERK2 signal, functional activation of estrogen receptor alpha in MCF-7 cells

RNA / Immunohistochemistry / Enzyme Inhibitors / Biological Chemistry / Flavonoids / Signal Transduction / Biological Sciences / Adipose tissue / Humans / Biological / Leptin / Mitogen Activated Protein Kinase / CHEMICAL SCIENCES / Cell nucleus / HeLa cells / Disease Progression / Transfection / Ligands / Down-Regulation / Estrogen receptor alpha / Signal Transduction / Biological Sciences / Adipose tissue / Humans / Biological / Leptin / Mitogen Activated Protein Kinase / CHEMICAL SCIENCES / Cell nucleus / HeLa cells / Disease Progression / Transfection / Ligands / Down-Regulation / Estrogen receptor alpha

AKT Participates in Endothelial Dysfunction in Hypertension

Signal Transduction / Humans / Hypertension / Insulin / Endothelial Cells / Doppler Ultrasound / Nitric oxide / Animals / Vascular endothelium / Acetylcholine / Gene Selection / Endothelial dysfunction / Clinical Sciences / Rats / Nitric Oxide Synthase / Endothelial cell / Public health systems and services research / Blood Flow / Circulation / Primary Culture / Spontaneously Hypertensive Rats / Aorta / Vasodilation / Spontaneously Hypertensive Rat / Protein Transport / Gene Transfer / Isoproterenol / Doppler Ultrasound / Nitric oxide / Animals / Vascular endothelium / Acetylcholine / Gene Selection / Endothelial dysfunction / Clinical Sciences / Rats / Nitric Oxide Synthase / Endothelial cell / Public health systems and services research / Blood Flow / Circulation / Primary Culture / Spontaneously Hypertensive Rats / Aorta / Vasodilation / Spontaneously Hypertensive Rat / Protein Transport / Gene Transfer / Isoproterenol

MDA5 assembles into a polar helical filament on dsRNA

Multidisciplinary / Signal Transduction / Humans / Mice / Animals / Protein Secondary Structure Prediction / Adenosine Triphosphate / Protein Secondary Structure Prediction / Adenosine Triphosphate

Pituitary development: a complex, temporal regulated process dependent on specific transcriptional factors

Endocrinology / Transcription Factors / Animal Production / Signal Transduction / Humans / Mutation / Animals / Clinical Sciences / Pituitary Gland / Veterinary Sciences / Mutation / Animals / Clinical Sciences / Pituitary Gland / Veterinary Sciences

Membrane-bound methyltransferase complex VapA-VipC-VapB guides epigenetic control of fungal development

Transcription Factors / Signal Transduction / Biological Sciences / DNA methylation / Aspergillus Nidulans / Histones / Cell nucleus / DNA binding proteins / Protein Transport / Heterochromatin / Histones / Cell nucleus / DNA binding proteins / Protein Transport / Heterochromatin

Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans

Genomics / Multidisciplinary / Signal Transduction / Humans / Mutation / Cluster Analysis / Candida albicans / Host Pathogen Interactions / Candidemia / Nature Communications / Gene Expression Regulation / Case Control Studies / Cluster Analysis / Candida albicans / Host Pathogen Interactions / Candidemia / Nature Communications / Gene Expression Regulation / Case Control Studies

Structural and mechanistic comparison of prokaryotic and eukaryotic phosphoinositide-specific phospholipases C

Molecular Biology / Protein Folding / Catalysis / Phospholipids / Signal Transduction / Catalytic Mechanism / Crystal structure / Humans / Sequence alignment / Animals / Enzyme / Active site / Rats / Substrate Specificity / Bacillus Cereus / Virulence factor / Amino Acid Sequence / Structural Similarity Index / Second Messengers / Myo-inositol / Pathogenic Bacteria / Biochemistry and cell biology / Phospholipase C / Catalytic Mechanism / Crystal structure / Humans / Sequence alignment / Animals / Enzyme / Active site / Rats / Substrate Specificity / Bacillus Cereus / Virulence factor / Amino Acid Sequence / Structural Similarity Index / Second Messengers / Myo-inositol / Pathogenic Bacteria / Biochemistry and cell biology / Phospholipase C

Endothelin-1 induces connective tissue growth factor expression in cardiomyocytes

Apoptosis / Cardiovascular disease / Extracellular Matrix / Signal Transduction / Molecular / real time PCR / Tissue repair / Cell line / Humans / Mice / Animals / Male / Epidermal Growth Factor Receptor / Proteoglycans / Rats / Model System / Endothelin-1 / Cardiovascular Diseases / Wistar Rats / Cell Proliferation / Decorin / Intracellular Signaling / Gene Expression Regulation / Extracellular Matrix Proteins / real time PCR / Tissue repair / Cell line / Humans / Mice / Animals / Male / Epidermal Growth Factor Receptor / Proteoglycans / Rats / Model System / Endothelin-1 / Cardiovascular Diseases / Wistar Rats / Cell Proliferation / Decorin / Intracellular Signaling / Gene Expression Regulation / Extracellular Matrix Proteins

Characterization of a Designed Vascular Endothelial Growth Factor Receptor Antagonist Helical Peptide with Antiangiogenic Activity in Vivo

Organic Chemistry / Water / Medicinal Chemistry / Magnetic Resonance Spectroscopy / Signal Transduction / Humans / Endothelial Cells / Circular Dichroism / Mice / Animals / Peptides / Protein Secondary Structure Prediction / Medicinal / Cell Proliferation / Cell Survival / Humans / Endothelial Cells / Circular Dichroism / Mice / Animals / Peptides / Protein Secondary Structure Prediction / Medicinal / Cell Proliferation / Cell Survival

Characterization of a Designed Vascular Endothelial Growth Factor Receptor Antagonist Helical Peptide with Antiangiogenic Activity in Vivo

Organic Chemistry / Water / Medicinal Chemistry / Magnetic Resonance Spectroscopy / Signal Transduction / Humans / Endothelial Cells / Circular Dichroism / Mice / Animals / Peptides / Protein Secondary Structure Prediction / Medicinal / Cell Proliferation / Cell Survival / Humans / Endothelial Cells / Circular Dichroism / Mice / Animals / Peptides / Protein Secondary Structure Prediction / Medicinal / Cell Proliferation / Cell Survival

Endometrial progesterone resistance and PCOS

Signal Transduction / Biological Sciences / Progesterone / Humans / Biomedical science / Female / Polycystic Ovary Syndrome / Endometrium / Gene Expression Regulation / Endometrial Hyperplasia / Female / Polycystic Ovary Syndrome / Endometrium / Gene Expression Regulation / Endometrial Hyperplasia

Cell-Permeable Gomesin Peptide Promotes Cell Death by Intracellular Ca 2+ Overload

Calcium / Mitochondria / Signal Transduction / Cell line / Reactive Oxygen Species / Animals / Cell Death / Endoplasmic Reticulum / Antimicrobial Cationic Peptides / Cytoplasm / Molecular Pharmaceutics / Animals / Cell Death / Endoplasmic Reticulum / Antimicrobial Cationic Peptides / Cytoplasm / Molecular Pharmaceutics

Vascular Endothelial Growth Factor-B Promotes In Vivo Angiogenesis

Cell Division / Signal Transduction / Capillaries / Collagen / Ischemia / Mice / Nitric oxide / Female / Animals / Male / Phosphorylation / Clinical Sciences / Mouse Model / Proteoglycans / Nitric Oxide Synthase / Western blot / Circulation / Matrix Metalloproteinases / Somatic Cell Count / Biological Assay / Methyl Ester / Neutralizing antibodies / Vascular Endothelial Growth Factor / Vascular endothelial growth factor receptor / Laminin / Mice / Nitric oxide / Female / Animals / Male / Phosphorylation / Clinical Sciences / Mouse Model / Proteoglycans / Nitric Oxide Synthase / Western blot / Circulation / Matrix Metalloproteinases / Somatic Cell Count / Biological Assay / Methyl Ester / Neutralizing antibodies / Vascular Endothelial Growth Factor / Vascular endothelial growth factor receptor / Laminin

Canonical Transient Receptor Potential 3 Channel Triggers Vascular Endothelial Growth Factor-Induced Intracellular Ca 2+ Oscillations in Endothelial Progenitor Cells Isolated from Umbilical Cord Blood

Physiology / Technology / Stem Cells / Calcium / Signal Transduction / Biological Sciences / RNA interference / Humans / Endothelial Cells / Female / Young Adult / Medical Physiology / Anti-inflammatory agents / Middle Aged / Adult / Cell Proliferation / Pyrazoles / Ion Transport / Biochemistry and cell biology / Biological Sciences / RNA interference / Humans / Endothelial Cells / Female / Young Adult / Medical Physiology / Anti-inflammatory agents / Middle Aged / Adult / Cell Proliferation / Pyrazoles / Ion Transport / Biochemistry and cell biology
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