Protein Binding

Ciprofloxacin penetration into extravascular spaces in a rabbit model

Microbiology / Medical Microbiology / Female / Animals / Ciprofloxacin / Rabbits / Quinolines / Protein Binding / Extracellular Space / Blood Proteins / Rabbits / Quinolines / Protein Binding / Extracellular Space / Blood Proteins

N-Arylalkylpiperidine urea derivatives as CC chemokine receptor-3 (CCR3) antagonists

Organic Chemistry / Drug interactions / Chemokines and chemokine receptors / Humans / Calcium Signaling / Urea / Eosinophils / Bioorganic and medicinal Chemistry / Structure activity Relationship / Protein Binding / Piperidines / Urea / Eosinophils / Bioorganic and medicinal Chemistry / Structure activity Relationship / Protein Binding / Piperidines

An AP endonuclease 1-DNA polymerase beta complex: theoretical prediction of interacting surfaces

Weak interaction / Biological Sciences / DNA / Crystal structure / Computer Simulation / Mathematical Sciences / Enzyme / Complexity Analysis / Binding Energy / Study design / Protein Conformation / Metabolic pathway / Protein Binding / MD Simulation / Molecular Dynamic Simulation / Nucleic Acid Conformation / Base Excision Repair / DNA Polymerase / Nucleotides / Visual Inspection / Mathematical Sciences / Enzyme / Complexity Analysis / Binding Energy / Study design / Protein Conformation / Metabolic pathway / Protein Binding / MD Simulation / Molecular Dynamic Simulation / Nucleic Acid Conformation / Base Excision Repair / DNA Polymerase / Nucleotides / Visual Inspection

The MTIP–Myosin A Complex in Blood Stage Malaria Parasites

Molecular Biology / Calcium / Membrane Proteins / Molecular / Motility / Animals / Blood / Myosin / Plasmodium falciparum / Protozoan Proteins / Protein Binding / Biochemistry and cell biology / Animals / Blood / Myosin / Plasmodium falciparum / Protozoan Proteins / Protein Binding / Biochemistry and cell biology

Gamma Interferon and Cadmium Treatments Modulate Eukaryotic Initiation Factor 4E-Dependent mRNA Transport of Cyclin D1 in a PML-Dependent Manner

Transcription Factors / Biological Sciences / Organelles / Molecular and cellular biology / Humans / Mutation / Mice / Animals / T cells / Transfection / Physiological Stress Markers / Recombinant Proteins / Protein Binding / Interferon gamma / Mutation / Mice / Animals / T cells / Transfection / Physiological Stress Markers / Recombinant Proteins / Protein Binding / Interferon gamma

Individual Timp Deficiencies Differentially Impact Pro-MMP-2 Activation

Biological Chemistry / Western blotting / Biological Sciences / Cell line / Humans / Mice / Animals / Biological / Proteins / Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis / CHEMICAL SCIENCES / Time Factors / Matrix Metalloproteinases / Human Fibroblasts / Recombinant Proteins / Protein Binding / Matrix Metalloproteinase / Mice / Animals / Biological / Proteins / Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis / CHEMICAL SCIENCES / Time Factors / Matrix Metalloproteinases / Human Fibroblasts / Recombinant Proteins / Protein Binding / Matrix Metalloproteinase

T84-Intestinal Epithelial Exosomes Bear MHC Class II/Peptide Complexes Potentiating Antigen Presentation by Dendritic Cells

Gastroenterology / Dendritic Cells / Cell line / Humans / Intestinal Mucosa / Antigen Presentation / Dendritic cell / Clinical Sciences / MHC class II / Protein Binding / Neurosciences / Gene Expression Regulation / Hybridomas / Serum albumin / Antigen Presentation / Dendritic cell / Clinical Sciences / MHC class II / Protein Binding / Neurosciences / Gene Expression Regulation / Hybridomas / Serum albumin

4E-BP Extends Lifespan upon Dietary Restriction by Enhancing Mitochondrial Activity in Drosophila

Drosophila melanogaster / Mitochondria / Gene expression / Biological Sciences / Longevity / Dietary Restriction / Animals / Cell / Caloric Restriction / Protein Binding / Life Span / Translation initiation / Protein Biosynthesis / Dietary Restriction / Animals / Cell / Caloric Restriction / Protein Binding / Life Span / Translation initiation / Protein Biosynthesis

Arabidopsis thaliana and Saccharomyces cerevisiae NHX1 genes encode amiloride sensitive electroneutral Na+/H+ exchangers

Hydrogen / Arabidopsis thaliana / Biological Sciences / Saccharomyces cerevisiae / Diuretics / Biochemical / Arabidopsis / Phenotype / CHEMICAL SCIENCES / Molecular cloning / Sodium / Ion Transport / Salts / Protein Binding / Hydrogen-Ion Concentration / PLANT PROTEINS / Vacuoles / Biochemical / Arabidopsis / Phenotype / CHEMICAL SCIENCES / Molecular cloning / Sodium / Ion Transport / Salts / Protein Binding / Hydrogen-Ion Concentration / PLANT PROTEINS / Vacuoles

Imidazopyridines as VLA-4 integrin antagonists

Organic Chemistry / Pharmaceutical Chemistry / Humans / Mice / Animals / Drug Design / Rats / Phenylalanine / Pyridines / Molecular Conformation / Bioorganic and medicinal Chemistry / Structure activity Relationship / Protein Binding / Drug Design / Rats / Phenylalanine / Pyridines / Molecular Conformation / Bioorganic and medicinal Chemistry / Structure activity Relationship / Protein Binding

Interactome Analyses of Mature  -Secretase Complexes Reveal Distinct Molecular Environments of Presenilin (PS) Paralogs and Preferential Binding of Signal Peptide Peptidase to PS2

Membrane Proteins / Biological Chemistry / Biological Sciences / Humans / Mutation / Mice / Animals / CHEMICAL SCIENCES / Presenilin-2 / Protein Binding / Alzheimer Disease / Mice / Animals / CHEMICAL SCIENCES / Presenilin-2 / Protein Binding / Alzheimer Disease

Allosteric  1-Adrenoreceptor Antagonism by the Conopeptide  -TIA

Kinetics / Fluorescence Microscopy / Biological Chemistry / Biological Sciences / Smooth muscle / Animals / Male / Peptides / CHEMICAL SCIENCES / Rats / Time Factors / Arginine / Wistar Rats / Protein Conformation / Alanine / Amino Acid Sequence / Structure activity Relationship / Protein Binding / Binding Site / Full Length Movies / Animals / Male / Peptides / CHEMICAL SCIENCES / Rats / Time Factors / Arginine / Wistar Rats / Protein Conformation / Alanine / Amino Acid Sequence / Structure activity Relationship / Protein Binding / Binding Site / Full Length Movies

Arl13b regulates endocytic recycling traffic

Multidisciplinary / Gene Silencing / Humans / Endocytosis / Cluster Analysis / Transferrin / Actin Cytoskeleton / HeLa cells / Protein Binding / Endosomes / Protein Transport / Transferrin / Actin Cytoskeleton / HeLa cells / Protein Binding / Endosomes / Protein Transport

Functional characterization of B class MADS-box transcription factors in Gerbera hybrida

Botany / Plant Biology / Flower Development / DNA / Phylogeny / Experimental Botany / Flowers / Phylogenetic analysis / Tomato / Asteraceae / Phenotype / Transcription Factor / Evo Devo / Gene Function / Protein Binding / Expression analysis / Gene expression profiling / Plant Epidermis / Down-Regulation / Experimental Botany / Flowers / Phylogenetic analysis / Tomato / Asteraceae / Phenotype / Transcription Factor / Evo Devo / Gene Function / Protein Binding / Expression analysis / Gene expression profiling / Plant Epidermis / Down-Regulation

An amplified DNA element in Leishmania encodes potential integral membrane and nucleotide-binding proteins

Membrane Proteins / Biological Sciences / Molecular / Animals / Guanosine Triphosphate / Protozoan Proteins / Leishmania infantum / Amino Acid Sequence / Base Sequence / Protein Binding / Nucleotides / Adenosine Triphosphate / Protozoan Proteins / Leishmania infantum / Amino Acid Sequence / Base Sequence / Protein Binding / Nucleotides / Adenosine Triphosphate

Functional characterization of B class MADS-box transcription factors in Gerbera hybrida

Botany / Plant Biology / Flower Development / DNA / Phylogeny / Experimental Botany / Flowers / Phylogenetic analysis / Tomato / Asteraceae / Phenotype / Transcription Factor / Evo Devo / Gene Function / Protein Binding / Expression analysis / Gene expression profiling / Plant Epidermis / Down-Regulation / Experimental Botany / Flowers / Phylogenetic analysis / Tomato / Asteraceae / Phenotype / Transcription Factor / Evo Devo / Gene Function / Protein Binding / Expression analysis / Gene expression profiling / Plant Epidermis / Down-Regulation
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