Protein Binding

Differential sensitivities of transcription factor target genes underlie cell type-specific gene expression profiles

Multidisciplinary / Cell line / Transcription Factor / Clinical Sciences / Protein Binding / Gene Expression Regulation / Gene expression profiling / Gene Expression Regulation / Gene expression profiling

Human Freud-2/CC2D1B: A Novel Repressor of Postsynaptic Serotonin-1A Receptor Expression

Polymorphism / Biological Sciences / Biological Psychiatry / Serotonin / Brain / Humans / Major Depressive Disorder / Male / Biological / Transcription Factor / Neuroblastoma / Middle Aged / Molecular cloning / Adult / Transfection / Protein Binding / DNA binding proteins / Down-Regulation / Humans / Major Depressive Disorder / Male / Biological / Transcription Factor / Neuroblastoma / Middle Aged / Molecular cloning / Adult / Transfection / Protein Binding / DNA binding proteins / Down-Regulation

Amino acid preferences at protein binding sites

Macromolecular X-Ray Crystallography / Enzymes / Proteins / Amino Acids / Amino Acid Profile / Protein Conformation / Structure activity Relationship / Protein Binding / Ligands / Biochemistry and cell biology / Protein Conformation / Structure activity Relationship / Protein Binding / Ligands / Biochemistry and cell biology

Antitopes Define Preferential Proteasomal Cleavage Site Usage

Mass Spectrometry / Biological Chemistry / Biological Sciences / Mice / Animals / Biological / Peptides / CHEMICAL SCIENCES / Substrate Specificity / Multienzyme complexes / Amino Acid Sequence / Protein Binding / Epitopes / Enterovirus / Biological / Peptides / CHEMICAL SCIENCES / Substrate Specificity / Multienzyme complexes / Amino Acid Sequence / Protein Binding / Epitopes / Enterovirus

A non-glycosylated extracellular superoxide dismutase variant

Biological Sciences / Heparin / Animals / Biochemical / Solubility / Superoxide Dismutase / Glycosylation / High Pressure Liquid Chromatography / CHEMICAL SCIENCES / Molecular weight / Rabbits / Structure activity Relationship / Recombinant Proteins / Protein Binding / Extracellular Space / Superoxide Dismutase / Glycosylation / High Pressure Liquid Chromatography / CHEMICAL SCIENCES / Molecular weight / Rabbits / Structure activity Relationship / Recombinant Proteins / Protein Binding / Extracellular Space

Structures of RNA polymerase–antibiotic complexes

RNA polymerase / Bacteria / Anti-Bacterial Agents / Protein Binding / Biochemistry and cell biology

[ 177 Lu]Bz-DTPA-EGF: Preclinical Characterization of a Potential Radionuclide Targeting Agent Against Glioma

Humans / Mice / Glioblastoma / Animals / Epidermal Growth Factor / Radiopharmaceuticals / Sensitivity and Specificity / Radioisotopes / Protein Binding / Chelating Agents / Radiopharmaceuticals / Sensitivity and Specificity / Radioisotopes / Protein Binding / Chelating Agents

Evidence in oyster of a plasma extracellular superoxide dismutase which binds LPS

Lipopolysaccharide / Escherichia coli / Animals / Connective tissue / Superoxide Dismutase / Lipopolysaccharides / Crassostrea gigas / Biological activity / Species Specificity / Amino Acid Sequence / Protein Binding / Blood Vessel / Biochemistry and cell biology / Lipopolysaccharides / Crassostrea gigas / Biological activity / Species Specificity / Amino Acid Sequence / Protein Binding / Blood Vessel / Biochemistry and cell biology

Substituted 3-amino biaryl propionic acids as potent VLA-4 antagonists

Organic Chemistry / Humans / Propionic Acid / Alanine / Bioorganic and medicinal Chemistry / Structure activity Relationship / Protein Binding / Biological Availability / Structure activity Relationship / Protein Binding / Biological Availability

Heparan Sulfate Plays a Central Role in a Dynamic in Vitro Model of Protein-losing Enteropathy

Flow Cytometry / Cytokines / Inflammation / Biological Chemistry / Confocal Microscopy / Biological Sciences / Cell line / Humans / Heparin / CHEMICAL SCIENCES / Hydrogen Peroxide / Pressure / Intestines / Epithelial cells / Time Factors / Tumor necrosis factor-alpha / Protein Conformation / Protein Binding / Interferon gamma / Biological Sciences / Cell line / Humans / Heparin / CHEMICAL SCIENCES / Hydrogen Peroxide / Pressure / Intestines / Epithelial cells / Time Factors / Tumor necrosis factor-alpha / Protein Conformation / Protein Binding / Interferon gamma

Peptide chemical ligation inside living cells: in vivo generation of a circular protein domain

Organic Chemistry / Mass Spectrometry / Protein Engineering / Escherichia coli / Mice / Animals / Magnetic Resonance / Cyclic peptides / Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis / High Pressure Liquid Chromatography / Protein Domains / Liquid Chromatography / Quantum correlations / Cyclization / Amino Acid Profile / Bioorganic and medicinal Chemistry / Biological activity / Protein Binding / Animals / Magnetic Resonance / Cyclic peptides / Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis / High Pressure Liquid Chromatography / Protein Domains / Liquid Chromatography / Quantum correlations / Cyclization / Amino Acid Profile / Bioorganic and medicinal Chemistry / Biological activity / Protein Binding

Structural dynamics as a contributor to error-prone replication by an RNA-dependent RNA polymerase

Molecular Dynamics Simulation / Kinetics / Biological Chemistry / Macromolecular X-Ray Crystallography / Biological Sciences / Mutation / CHEMICAL SCIENCES / Protein Secondary Structure Prediction / Protein Binding / Nucleotides / Poliovirus / Mutation / CHEMICAL SCIENCES / Protein Secondary Structure Prediction / Protein Binding / Nucleotides / Poliovirus

Tbx3 Represses E-Cadherin Expression and Enhances Melanoma Invasiveness

Cancer / Cell Adhesion / Humans / Melanoma / Calcium Signaling / Phase transition / Transcription Factor / Neoplasm Invasiveness / Cell Proliferation / Base Sequence / Protein Binding / Down-Regulation / Phase transition / Transcription Factor / Neoplasm Invasiveness / Cell Proliferation / Base Sequence / Protein Binding / Down-Regulation

The Epithelial-Mesenchymal Transition Factor SNAIL Paradoxically Enhances Reprogramming

Cellular Reprogramming / Confocal Microscopy / Transcription Factors / Gene expression / Epithelial-Mesenchymal Transition / RNA interference / Cell Differentiation / Humans / Keratinocytes / Animals / microRNAs / Induced Pluripotent Stem Cells / Human Fibroblasts / Protein Binding / RNA interference / Cell Differentiation / Humans / Keratinocytes / Animals / microRNAs / Induced Pluripotent Stem Cells / Human Fibroblasts / Protein Binding

Intracellular Insulin-like Growth Factor-1 Induces Bcl-2 Expression in Airway Epithelial Cells

Immunology / Cystic Fibrosis / Immunology of the Gut / Gene Silencing / Humans / Mice / Chronic Disease / Animals / Male / Lipopolysaccharides / Rats / Epithelial cells / Protein Binding / Gene Expression Regulation / Gene expression profiling / Mice / Chronic Disease / Animals / Male / Lipopolysaccharides / Rats / Epithelial cells / Protein Binding / Gene Expression Regulation / Gene expression profiling

Motif D of Viral RNA-Dependent RNA Polymerases Determines Efficiency and Fidelity of Nucleotide Addition

Structure / Magnetic Resonance Spectroscopy / Biocatalysis / Biological Sciences / CHEMICAL SCIENCES / Hydrogen Bonding / Base Sequence / Protein Binding / Nucleotides / Poliovirus / Hydrogen Bonding / Base Sequence / Protein Binding / Nucleotides / Poliovirus

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