Protein Binding - Page 15

New 7,8-ethylenedioxy-2,3-benzodiazepines as noncompetitive AMPA receptor antagonists

Organic Chemistry / Pharmaceutical Chemistry / Humans / Mice / DBA / Animals / Drug Design / Benzodiazepines / Rats / Bioorganic and medicinal Chemistry / Structure activity Relationship / Protein Binding / Functional Testing / Animals / Drug Design / Benzodiazepines / Rats / Bioorganic and medicinal Chemistry / Structure activity Relationship / Protein Binding / Functional Testing

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Phenylalanyl-tRNA synthetase of Escherichia coli K 10. Multiple enzyme.cntdot.aminoacyl-tRNA complexes as a consequence of substrate specificity

Biochemistry / Mathematics / Kinetics / Escherichia coli / Zinc / Substrate Specificity / Protein Conformation / Protein Binding / Biochemistry and cell biology / Substrate Specificity / Protein Conformation / Protein Binding / Biochemistry and cell biology

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A luminal flavoprotein in endoplasmic reticulum-associated degradation

Multidisciplinary / Molecular chaperones / Cell line / Humans / Sequence alignment / Endoplasmic Reticulum / Lectins / Proteins / Glycosylation / Amino Acid Sequence / Protein Binding / Ubiquitination / Endoplasmic Reticulum / Lectins / Proteins / Glycosylation / Amino Acid Sequence / Protein Binding / Ubiquitination

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Stearoyl-Coenzyme A Desaturase 1 Deficiency Protects against Hypertriglyceridemia and Increases Plasma High-Density Lipoprotein Cholesterol Induced by Liver X Receptor Activation

Transcription Regulation / Biological Sciences / Lipids / Molecular and cellular biology / Humans / Mice / Animals / Lipid metabolism / Lipoprotein(a) / Enzyme / Orphan Nuclear Receptors / Base Sequence / Protein Binding / DNA binding proteins / Response Elements / Stearoyl-CoA desaturase / Mice / Animals / Lipid metabolism / Lipoprotein(a) / Enzyme / Orphan Nuclear Receptors / Base Sequence / Protein Binding / DNA binding proteins / Response Elements / Stearoyl-CoA desaturase

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Human infection with Trypanosoma cruzi induces parasite antigen-specific cytotoxic T lymphocyte responses

Membrane Proteins / Cell line / Humans / Animals / Clinical / Immunization / Chagas disease / Neuraminidase / Trypanosoma Cruzi / Protein Binding / Clinical Investigation / Epitopes / Immunization / Chagas disease / Neuraminidase / Trypanosoma Cruzi / Protein Binding / Clinical Investigation / Epitopes

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A multicopper ferroxidase involved in iron binding to transferrins in Dunaliella salina plasma membranes

Biological Chemistry / Biological Sciences / Transferrin / Iron / CHEMICAL SCIENCES / Molecular cloning / Ceruloplasmin / Autoradiography / Amino Acid Sequence / Base Sequence / Protein Binding / Oxidation-Reduction / Molecular cloning / Ceruloplasmin / Autoradiography / Amino Acid Sequence / Base Sequence / Protein Binding / Oxidation-Reduction

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Ero1α Regulates Ca 2+ Fluxes at the Endoplasmic Reticulum–Mitochondria Interface (MAM)

Calcium / Membrane Proteins / Mitochondria / Signal Transduction / Molecular chaperones / Cell line / Humans / Oxidoreductases / Endoplasmic Reticulum / Homeostasis / Protein Binding / Oxidation-Reduction / Cell line / Humans / Oxidoreductases / Endoplasmic Reticulum / Homeostasis / Protein Binding / Oxidation-Reduction

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Structural Insights into Antibody Recognition of Mycobacterial Polysaccharides

Molecular Biology / Macromolecular X-Ray Crystallography / Molecular / Tuberculosis / Mycobacterium / Mice / Animals / Monoclonal Antibodies / Lipopolysaccharides / Amino Acid Sequence / Protein Binding / Biochemistry and cell biology / Branch point / Mice / Animals / Monoclonal Antibodies / Lipopolysaccharides / Amino Acid Sequence / Protein Binding / Biochemistry and cell biology / Branch point

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Ero1α Regulates Ca 2+ Fluxes at the Endoplasmic Reticulum–Mitochondria Interface (MAM)

Calcium / Membrane Proteins / Mitochondria / Signal Transduction / Molecular chaperones / Cell line / Humans / Oxidoreductases / Endoplasmic Reticulum / Homeostasis / Protein Binding / Oxidation-Reduction / Cell line / Humans / Oxidoreductases / Endoplasmic Reticulum / Homeostasis / Protein Binding / Oxidation-Reduction

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New 7,8-ethylenedioxy-2,3-benzodiazepines as noncompetitive AMPA receptor antagonists

Organic Chemistry / Pharmaceutical Chemistry / Humans / Mice / DBA / Animals / Drug Design / Benzodiazepines / Rats / Bioorganic and medicinal Chemistry / Structure activity Relationship / Protein Binding / Functional Testing / Animals / Drug Design / Benzodiazepines / Rats / Bioorganic and medicinal Chemistry / Structure activity Relationship / Protein Binding / Functional Testing

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Reduced parahippocampal and lateral temporal GABAA-[11C]flumazenil binding in major depression: preliminary results

Treatment Outcome / Positron Emission Tomography / Corticotropin Releasing Hormone / Temporal Lobe / Dexamethasone / Humans / Major Depressive Disorder / Female / Male / HPA axis / Depressive Disorder / Clinical Sciences / European / Major Depression / Butyric Acid / Adult / Parahippocampal Gyrus / Protein Binding / Region of Interest / Gamma-Aminobutyric Acid / Case Control Studies / Dorsolateral Prefrontal Cortex / Flumazenil / Humans / Major Depressive Disorder / Female / Male / HPA axis / Depressive Disorder / Clinical Sciences / European / Major Depression / Butyric Acid / Adult / Parahippocampal Gyrus / Protein Binding / Region of Interest / Gamma-Aminobutyric Acid / Case Control Studies / Dorsolateral Prefrontal Cortex / Flumazenil

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CDK13, a New Potential Human Immunodeficiency Virus Type 1 Inhibitory Factor Regulating Viral mRNA Splicing

Virology / Gene expression / HIV / Biological Sciences / Humans / Chromatin remodeling / Immunoprecipitation / Enzyme / Human immunodeficiency virus / HeLa cells / Protein Binding / Chromatin remodeling / Immunoprecipitation / Enzyme / Human immunodeficiency virus / HeLa cells / Protein Binding

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Major human γ-aminobutyrate transporter: In silico prediction of substrate efficacy

Molecular Dynamics / Homology Modeling / Crystal structure / Humans / Computer Simulation / Ligand Binding / Substrate Specificity / Protein Conformation / In Silico / Protein Binding / Antiepileptic Drug / Molecular Dynamic Simulation / Gamma-Aminobutyric Acid / Biochemistry and cell biology / Ligand Binding / Substrate Specificity / Protein Conformation / In Silico / Protein Binding / Antiepileptic Drug / Molecular Dynamic Simulation / Gamma-Aminobutyric Acid / Biochemistry and cell biology

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A chicken c-Rel-estrogen receptor chimeric protein shows conditional nuclear localization, DNA binding, transformation and transcriptional activation

Gene expression / Estrogen Receptor / DNA / Humans / Animals / Oncogene / NF-kappa B / Phenotype / Clinical Sciences / Cell nucleus / HeLa cells / DNA binding / Base Sequence / Quail / Human Fibroblasts / Subcellular Fractions / Protein Binding / DNA binding proteins / Cell Cycle Control / Nuclear Localization / Cell Growth / Oncogene / NF-kappa B / Phenotype / Clinical Sciences / Cell nucleus / HeLa cells / DNA binding / Base Sequence / Quail / Human Fibroblasts / Subcellular Fractions / Protein Binding / DNA binding proteins / Cell Cycle Control / Nuclear Localization / Cell Growth

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Intramolecular loop/tail interactions are essential for connexin 43-hemichannel activity

Physiology / Calcium / Cornea / Ion Channels / Cell line / Thrombin / Humans / Endothelial Cells / Animals / Medical Physiology / Cattle / Rats / HeLa cells / Xenopus laevis / Connexin / Oocytes / Protein Binding / Intracellular Space / Biochemistry and cell biology / Adenosine Triphosphate / Thrombin / Humans / Endothelial Cells / Animals / Medical Physiology / Cattle / Rats / HeLa cells / Xenopus laevis / Connexin / Oocytes / Protein Binding / Intracellular Space / Biochemistry and cell biology / Adenosine Triphosphate

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Major human γ-aminobutyrate transporter: In silico prediction of substrate efficacy

Molecular Dynamics / Homology Modeling / Crystal structure / Humans / Computer Simulation / Ligand Binding / Substrate Specificity / Protein Conformation / In Silico / Protein Binding / Antiepileptic Drug / Molecular Dynamic Simulation / Gamma-Aminobutyric Acid / Biochemistry and cell biology / Ligand Binding / Substrate Specificity / Protein Conformation / In Silico / Protein Binding / Antiepileptic Drug / Molecular Dynamic Simulation / Gamma-Aminobutyric Acid / Biochemistry and cell biology

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