Neuropharmacology

3-Aminocyclopentyl)methylphosphinic acids: Novel GABA C receptor antagonists

Psychology / Neuropharmacology / Drug interactions / Patch-clamp and imaging techniques / Humans / GABA receptors / Female / Animals / Central Nervous System / Organophosphorus Compounds / Xenopus laevis / Oocytes / Neurosciences / Gamma-Aminobutyric Acid / GABA receptors / Female / Animals / Central Nervous System / Organophosphorus Compounds / Xenopus laevis / Oocytes / Neurosciences / Gamma-Aminobutyric Acid

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The in vitro and in vivo enantioselectivity of etomidate implicates the GABA A receptor in general anaesthesia

Psychology / Neuropharmacology / Cell line / Evoked Potentials / Humans / Thalamus / Mice / Female / Animals / Male / Acetylcholine / Rat Brain / Synaptic Transmission / Rats / Radioligand Assay / Larva / Reflex / Xenopus laevis / Locomotor Activity / Oocytes / Structure activity Relationship / Neurosciences / GABA receptor / Glutamate Receptor / Etomidate / Thalamus / Mice / Female / Animals / Male / Acetylcholine / Rat Brain / Synaptic Transmission / Rats / Radioligand Assay / Larva / Reflex / Xenopus laevis / Locomotor Activity / Oocytes / Structure activity Relationship / Neurosciences / GABA receptor / Glutamate Receptor / Etomidate

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A novel multi-target ligand (JM-20) protects mitochondrial integrity, inhibits brain excitatory amino acid release and reduces cerebral ischemia injury in vitro and in vivo

Psychology / Neuropharmacology / Mitochondria / Neuroprotection / Brain / Glucose / Animals / Plant tissue Culture Techniques / Male / Cell Death / Benzodiazepines / Brain Ischemia / Wistar Rats / Neurosciences / Excitatory Amino Acids / Neuroprotective Agents / Random Allocation / Glucose / Animals / Plant tissue Culture Techniques / Male / Cell Death / Benzodiazepines / Brain Ischemia / Wistar Rats / Neurosciences / Excitatory Amino Acids / Neuroprotective Agents / Random Allocation

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DREADDs: NUEVAS HERRAMIENTAS FARMACOLÓGICAS PARA EL CONTROL NEURONAL REMOTO ACTIVADO POR LIGANDOS SINTÉTICOS - (DREADDs: New pharmacological tools for remote neuronal control activated by synthetic ligands).

Neuroscience / Neuropharmacology / Optogenetics / DREADDs

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Retinoic acid negatively regulates neuropeptide Y expression in human neuroblastoma cells

Psychology / Neuropharmacology / Gene expression / Cell line / Cell Differentiation / Humans / Transcription Factor / Neuroblastoma / Neuropeptide Y / Retinoic Acid / Tretinoin / Nervous System / Neurosciences / Phorbol ester / Humans / Transcription Factor / Neuroblastoma / Neuropeptide Y / Retinoic Acid / Tretinoin / Nervous System / Neurosciences / Phorbol ester

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A novel multi-target ligand (JM-20) protects mitochondrial integrity, inhibits brain excitatory amino acid release and reduces cerebral ischemia injury in vitro and in vivo

Psychology / Neuropharmacology / Mitochondria / Neuroprotection / Brain / Glucose / Animals / Plant tissue Culture Techniques / Male / Cell Death / Benzodiazepines / Brain Ischemia / Wistar Rats / Neurosciences / Excitatory Amino Acids / Neuroprotective Agents / Glucose / Animals / Plant tissue Culture Techniques / Male / Cell Death / Benzodiazepines / Brain Ischemia / Wistar Rats / Neurosciences / Excitatory Amino Acids / Neuroprotective Agents

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(3-Aminocyclopentyl)methylphosphinic acids: Novel GABA C receptor antagonists

Psychology / Neuropharmacology / Drug interactions / Patch-clamp and imaging techniques / Humans / GABA receptors / Female / Animals / Central Nervous System / Organophosphorus Compounds / Xenopus laevis / Oocytes / Neurosciences / Gamma-Aminobutyric Acid / GABA receptors / Female / Animals / Central Nervous System / Organophosphorus Compounds / Xenopus laevis / Oocytes / Neurosciences / Gamma-Aminobutyric Acid

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Antisense ‘knockdowns’ of M1 receptors induces transient anterograde amnesia in mice

Psychology / Neuropharmacology / Memory / Hippocampus / Cerebral Cortex / Mice / Animals / Amnesia / Male / Reaction Time / Time Factors / Degeneration / Antisense Oligonucleotide Drugs / Neurosciences / Control Group / Mice / Animals / Amnesia / Male / Reaction Time / Time Factors / Degeneration / Antisense Oligonucleotide Drugs / Neurosciences / Control Group

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N-desalkylquetiapine activates ERK1/2 to induce GDNF release in C6 glioma cells: A putative cellular mechanism for quetiapine as antidepressant

Psychology / Neuropharmacology / Glioma / Animals / Mitogen Activated Protein Kinase / Rats / Pyridines / Transfection / GDNF / Neurosciences / Enzyme Linked Immunosorbent Assay / Rats / Pyridines / Transfection / GDNF / Neurosciences / Enzyme Linked Immunosorbent Assay

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5-HT receptor agonists modify epileptic seizures in three experimental models in rats

Psychology / Neuropharmacology / Status Epilepticus / Neurosciences / Mortality rate / Experimental Model

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Intracellular cholesterol changes induced by translocator protein (18 kDa) TSPO/PBR ligands

Psychology / Neuropharmacology / Membrane Proteins / Cell line / Mice / GABA receptors / Cholesterol / Animals / Astrocyte / Astrocytes / Time Factors / Exocytosis / Human Fibroblasts / Antineoplastic Agents / Ligands / Neurosciences / GABA receptor / GABA receptors / Cholesterol / Animals / Astrocyte / Astrocytes / Time Factors / Exocytosis / Human Fibroblasts / Antineoplastic Agents / Ligands / Neurosciences / GABA receptor

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Intracellular cholesterol changes induced by translocator protein (18 kDa) TSPO/PBR ligands

Psychology / Neuropharmacology / Membrane Proteins / Cell line / Mice / GABA receptors / Cholesterol / Animals / Astrocyte / Astrocytes / Time Factors / Exocytosis / Human Fibroblasts / Antineoplastic Agents / Ligands / Neurosciences / GABA receptor / GABA receptors / Cholesterol / Animals / Astrocyte / Astrocytes / Time Factors / Exocytosis / Human Fibroblasts / Antineoplastic Agents / Ligands / Neurosciences / GABA receptor

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Transient Receptor Potential Vanilloid 1 Agonists Cause Endoplasmic Reticulum Stress and Cell Death in Human Lung Cells

Pharmacology / Psychology / Long Term Potentiation / Neuropharmacology / Calcium / Enzyme Inhibitors / Endoplasmic Reticulum Stress / Gene expression / Low Frequency / Synaptic Plasticity / Cell line / Learning and Memory / Humans / Animals / Male / Cell Death / Endoplasmic Reticulum / Phosphorylation / Lung / Capsaicin / Long Term Depression / Thiourea / Rats / Epithelial cells / Diterpenes / Transfection / Endocannabinoids / Cell Survival / Neurosciences / Low Frequency Stimulation / Gamma-Aminobutyric Acid / Enzyme Inhibitors / Endoplasmic Reticulum Stress / Gene expression / Low Frequency / Synaptic Plasticity / Cell line / Learning and Memory / Humans / Animals / Male / Cell Death / Endoplasmic Reticulum / Phosphorylation / Lung / Capsaicin / Long Term Depression / Thiourea / Rats / Epithelial cells / Diterpenes / Transfection / Endocannabinoids / Cell Survival / Neurosciences / Low Frequency Stimulation / Gamma-Aminobutyric Acid

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Antisense ‘knockdowns’ of M1 receptors induces transient anterograde amnesia in mice

Psychology / Neuropharmacology / Memory / Hippocampus / Cerebral Cortex / Mice / Animals / Amnesia / Male / Reaction Time / Time Factors / Degeneration / Antisense Oligonucleotide Drugs / Neurosciences / Control Group / Mice / Animals / Amnesia / Male / Reaction Time / Time Factors / Degeneration / Antisense Oligonucleotide Drugs / Neurosciences / Control Group

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The in vitro and in vivo enantioselectivity of etomidate implicates the GABAA receptor in general anaesthesia

Psychology / Neuropharmacology / Cell line / Evoked Potentials / Humans / Thalamus / Mice / Female / Animals / Male / Acetylcholine / Rat Brain / Synaptic Transmission / Rats / Radioligand Assay / Larva / Reflex / Xenopus laevis / Locomotor Activity / Oocytes / Structure activity Relationship / Neurosciences / GABA receptor / Glutamate Receptor / Etomidate / Thalamus / Mice / Female / Animals / Male / Acetylcholine / Rat Brain / Synaptic Transmission / Rats / Radioligand Assay / Larva / Reflex / Xenopus laevis / Locomotor Activity / Oocytes / Structure activity Relationship / Neurosciences / GABA receptor / Glutamate Receptor / Etomidate

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Hippocampal extracellular amino acids and EEG spectral analysis in a genetic rat model of absence epilepsy

Genetics / Psychology / Neuropharmacology / Electroencephalography / Learning / Hippocampus / Glutamate / Absence epilepsy / Spectral analysis / Female / Animals / Cognitive Process / Oscillations / Microdialysis / Amino Acids / Baclofen / Rats / Wistar Rats / Amino Acid Profile / Rat Model / Neurosciences / Extracellular Space / Hippocampus / Glutamate / Absence epilepsy / Spectral analysis / Female / Animals / Cognitive Process / Oscillations / Microdialysis / Amino Acids / Baclofen / Rats / Wistar Rats / Amino Acid Profile / Rat Model / Neurosciences / Extracellular Space

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