Mouse Model

Gene expression profiling of mouse p53-deficient epidermal carcinoma defines molecular determinants of human cancer malignancy

Breast Cancer / Cell Cycle / Human embryonic stem cell / Gene expression / Molecular Biology Cancer / Molecular / Humans / Mice / Animals / Multiple Myeloma / Cervical Cancer / Mouse Model / Microarray Analysis / Neoplasms / Targeted Therapy / Chromosomal Instability / Gene expression profiling / Skin Neoplasms / Molecular / Humans / Mice / Animals / Multiple Myeloma / Cervical Cancer / Mouse Model / Microarray Analysis / Neoplasms / Targeted Therapy / Chromosomal Instability / Gene expression profiling / Skin Neoplasms

Gene expression profiling of mouse p53-deficient epidermal carcinoma defines molecular determinants of human cancer malignancy

Breast Cancer / Cell Cycle / Human embryonic stem cell / Gene expression / Molecular Biology Cancer / Molecular / Humans / Mice / Animals / Multiple Myeloma / Cervical Cancer / Mouse Model / Microarray Analysis / Neoplasms / Targeted Therapy / Chromosomal Instability / Gene expression profiling / Skin Neoplasms / Molecular / Humans / Mice / Animals / Multiple Myeloma / Cervical Cancer / Mouse Model / Microarray Analysis / Neoplasms / Targeted Therapy / Chromosomal Instability / Gene expression profiling / Skin Neoplasms

TRAIL shows potential cardioprotective activity

Clinical Trial / Apoptosis / Mice / Animals / Male / Fibrosis / Mouse Model / Type 2 Diabetes Mellitus / Recombinant Proteins / Fibrosis / Mouse Model / Type 2 Diabetes Mellitus / Recombinant Proteins

Credentialing a Preclinical Mouse Model of Alveolar Rhabdomyosarcoma

Cancer / Humans / Mice / Animals / Mouse Model / Disease Progression

Tesaglitazar, a dual peroxisome proliferator-activated receptor alpha/gamma agonist, reduces atherosclerosis in female low density lipoprotein receptor deficient mice

Atherosclerosis / Lipids / Blood Glucose / Mice / Cholesterol / Female / Animals / Male / Peroxisome proliferator-activated receptor / Transcription Factor / Clinical Sciences / Mouse Model / Alkanesulfonates / Female / Animals / Male / Peroxisome proliferator-activated receptor / Transcription Factor / Clinical Sciences / Mouse Model / Alkanesulfonates

Myristoyl-CoA:Protein N-Myristoyltransferase, an Essential Enzyme and Potential Drug Target in Kinetoplastid Parasites

Kinetics / Drug development / Biological Chemistry / Leishmania / Cell Division / Biological Sciences / Saccharomyces cerevisiae / Molecular / RNA interference / Virulence / Cell line / Humans / Mice / Endocytosis / Animals / Cell Death / Biological / Polymerase Chain Reaction / Capsid / Phenotype / Enzyme / CHEMICAL SCIENCES / Mouse Model / Rats / Trypanosoma / Trypanosoma brucei / Time Factors / Trypanosoma brucei brucei / Isoenzymes / Fatty Acid / Protozoan Proteins / Species Specificity / Amino Acid Sequence / Subcellular Fractions / Golgi Apparatus / Recombinant Proteins / Drug Targeting / Cell Survival / Leishmania Major / Biochemistry and cell biology / Poliovirus / Immunoblotting / Biological Sciences / Saccharomyces cerevisiae / Molecular / RNA interference / Virulence / Cell line / Humans / Mice / Endocytosis / Animals / Cell Death / Biological / Polymerase Chain Reaction / Capsid / Phenotype / Enzyme / CHEMICAL SCIENCES / Mouse Model / Rats / Trypanosoma / Trypanosoma brucei / Time Factors / Trypanosoma brucei brucei / Isoenzymes / Fatty Acid / Protozoan Proteins / Species Specificity / Amino Acid Sequence / Subcellular Fractions / Golgi Apparatus / Recombinant Proteins / Drug Targeting / Cell Survival / Leishmania Major / Biochemistry and cell biology / Poliovirus / Immunoblotting

Myristoyl CoA: protein N-myristoyltransferase: an essential enzyme and potential drug target in kinetoplastid parasites

Kinetics / Drug development / Biological Chemistry / Leishmania / Cell Division / Biological Sciences / Saccharomyces cerevisiae / Molecular / RNA interference / Virulence / Cell line / Humans / Mice / Endocytosis / Animals / Cell Death / Biological / Polymerase Chain Reaction / Capsid / Phenotype / Enzyme / CHEMICAL SCIENCES / Mouse Model / Rats / Trypanosoma / Trypanosoma brucei / Time Factors / Trypanosoma brucei brucei / Isoenzymes / Fatty Acid / Protozoan Proteins / Species Specificity / Amino Acid Sequence / Subcellular Fractions / Golgi Apparatus / Recombinant Proteins / Drug Targeting / Cell Survival / Leishmania Major / Biochemistry and cell biology / Poliovirus / Immunoblotting / Biological Sciences / Saccharomyces cerevisiae / Molecular / RNA interference / Virulence / Cell line / Humans / Mice / Endocytosis / Animals / Cell Death / Biological / Polymerase Chain Reaction / Capsid / Phenotype / Enzyme / CHEMICAL SCIENCES / Mouse Model / Rats / Trypanosoma / Trypanosoma brucei / Time Factors / Trypanosoma brucei brucei / Isoenzymes / Fatty Acid / Protozoan Proteins / Species Specificity / Amino Acid Sequence / Subcellular Fractions / Golgi Apparatus / Recombinant Proteins / Drug Targeting / Cell Survival / Leishmania Major / Biochemistry and cell biology / Poliovirus / Immunoblotting

Disease Progression Despite Early Loss of Polyglutamine Protein Expression in SCA7 Mouse Model

Neuroscience / Gene expression / Transgenic Mice / Mice / Animals / Spinocerebellar ataxia / Retinal Degeneration / Protein Aggregation / Peptides / The / Mouse Model / Protein Expression / Neurodegenerative Disease / Age Factors / Disease Progression / Huntington disease / Recombinant Proteins / Rhodopsin / Full Length Movies / Down-Regulation / Spinocerebellar ataxia / Retinal Degeneration / Protein Aggregation / Peptides / The / Mouse Model / Protein Expression / Neurodegenerative Disease / Age Factors / Disease Progression / Huntington disease / Recombinant Proteins / Rhodopsin / Full Length Movies / Down-Regulation

Bone mineralization proceeds through intracellular calcium phosphate loaded vesicles: A cryo-electron microscopy study

Structural Biology / Hydroxyapatite / Electron Diffraction / Biomineralization / Extracellular Matrix / Mice / Animals / Skull / Fishes / Calcium Phosphates / Calcium Phosphate / Mouse Model / Cryo Electron Microscopy / Durapatite / X ray Computed Tomography / Bone and Bones / Biochemistry and cell biology / Intracellular Calcium / Mice / Animals / Skull / Fishes / Calcium Phosphates / Calcium Phosphate / Mouse Model / Cryo Electron Microscopy / Durapatite / X ray Computed Tomography / Bone and Bones / Biochemistry and cell biology / Intracellular Calcium

A diet-induced mouse model for glutaric aciduria type I

Magnetic Resonance Imaging / Diet / Survival Analysis / Brain / Mice / Blood brain barrier / Female / Animals / Plant tissue Culture Techniques / Male / Astrocyte / Animal Model / Neurons / Mouse Model / Lysine / Subarachnoid haemorrhage / Human Disease / Dietary Protein / High-protein Diet / Autosomal Recessive / White Matter Lesions / Blood brain barrier / Female / Animals / Plant tissue Culture Techniques / Male / Astrocyte / Animal Model / Neurons / Mouse Model / Lysine / Subarachnoid haemorrhage / Human Disease / Dietary Protein / High-protein Diet / Autosomal Recessive / White Matter Lesions

Neurobehavioral mutants identified in an ENU-mutagenesis project

Genetics / Animal Behavior / Fear / Learning and Memory / Prepulse Inhibition / Mutagenesis / Mice / High throughput screening / Female / Animals / Male / Open Field / Genetic Map / Central Nervous System / Mental Disorders / Pedigree / Mental Disorder / Mouse Model / Large Scale / Nervous System Diseases / Mutagenesis / Mice / High throughput screening / Female / Animals / Male / Open Field / Genetic Map / Central Nervous System / Mental Disorders / Pedigree / Mental Disorder / Mouse Model / Large Scale / Nervous System Diseases

Gastrointestinal Hyperplasia with Altered Expression of DNA Polymerase β

Engineering / Physics / Chemistry / Biology / DNA repair / Medicine / Multidisciplinary / Mice / Animals / Hyperplasia / PLoS one / Mouse Model / Protein Expression / Gastrointestinal Tract / Transgenic Mouse Technology / Base Excision Repair / DNA Polymerase / Medicine / Multidisciplinary / Mice / Animals / Hyperplasia / PLoS one / Mouse Model / Protein Expression / Gastrointestinal Tract / Transgenic Mouse Technology / Base Excision Repair / DNA Polymerase

Antifungal Therapy of Experimental Cerebral Phaeohyphomycosis Due to Cladophialophora bantiana

Microbiology / Medical Microbiology / Survival Analysis / Brain / Mice / Female / Animals / Immunosuppression / Central Nervous System / Sterilization / Fungal Pathogens / Spectrum / Mouse Model / Antifungal Agents / Soft Tissue / Ascomycota / Female / Animals / Immunosuppression / Central Nervous System / Sterilization / Fungal Pathogens / Spectrum / Mouse Model / Antifungal Agents / Soft Tissue / Ascomycota

3,3′-Diindolylmethane attenuates experimental arthritis and osteoclastogenesis

Cytokines / Mice / Female / Animals / Skull / Male / Osteoclasts / Animal Model / Biochemical / Mouse Model / Lipopolysaccharides / Rats / Edema / In vitro culture / BIOCHEMICAL PHARMACOLOGY / Rat Model / Bone Resorption / Male / Osteoclasts / Animal Model / Biochemical / Mouse Model / Lipopolysaccharides / Rats / Edema / In vitro culture / BIOCHEMICAL PHARMACOLOGY / Rat Model / Bone Resorption

Mouse Model for Human Arginase Deficiency

Cellular Biology / Gene Therapy / Biological Sciences / Molecular and cellular biology / Humans / Kidney / Liver / Mice / Female / Animals / Male / Nitrogen / Detoxification / Enzyme / Human Genome / Mouse Model / Mammary gland / Enzyme activity / Homologous Recombination / Quaternary Ammonium Compounds / Knockout Mice / Glutamic Acid / Growth Retardation / Kidney / Liver / Mice / Female / Animals / Male / Nitrogen / Detoxification / Enzyme / Human Genome / Mouse Model / Mammary gland / Enzyme activity / Homologous Recombination / Quaternary Ammonium Compounds / Knockout Mice / Glutamic Acid / Growth Retardation

An increase in superoxide dismutase ameliorates oxygen-induced retinopathy in transgenic mice

Immunology / Transgenic Mice / Humans / Copper / Mice / Animals / Zinc / Risk factors / Superoxide Dismutase / Enzyme / Clinical Sciences / Eye / Newborn Infant / Mouse Model / Optometry and Ophthalmology / Oxygen / Retinopathy of prematurity / Risk Factors / Retinal Diseases / Blood Vessel / Control Group / Animals / Zinc / Risk factors / Superoxide Dismutase / Enzyme / Clinical Sciences / Eye / Newborn Infant / Mouse Model / Optometry and Ophthalmology / Oxygen / Retinopathy of prematurity / Risk Factors / Retinal Diseases / Blood Vessel / Control Group
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