Mouse Model - Page 4

PARP inhibition or gene deficiency counteracts intraepidermal nerve fiber loss and neuropathic pain in advanced diabetic neuropathy

Immunohistochemistry / Enzyme Inhibitors / Type 2 Diabetes / Free Radical / Neuropathic pain / Mice / Animals / Male / Drinking Water / Skin / Diabetic Neuropathy / Mouse Model / Rats / Degeneration / Peripheral nerves / Peripheral Nerve / Wistar Rats / Combination drug therapy / Streptozotocin / Diabetic Rat / Organic Chemicals / Biochemistry and cell biology / Mice / Animals / Male / Drinking Water / Skin / Diabetic Neuropathy / Mouse Model / Rats / Degeneration / Peripheral nerves / Peripheral Nerve / Wistar Rats / Combination drug therapy / Streptozotocin / Diabetic Rat / Organic Chemicals / Biochemistry and cell biology

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Mitogenic Component in Polar Lipid-Enriched Anaplasma phagocytophilum Membranes

Immunology / Innate immunity / Toll like receptor signaling / Lipopolysaccharide / Spleen / Virulence / Humans / Intact polar lipids / Mice / Adaptive Immunity / Animals / Membrane Lipids / Lipoprotein(a) / Mouse Model / Cell Proliferation / Membrane Protein / Anaplasma Phagocytophilum / Virulence / Humans / Intact polar lipids / Mice / Adaptive Immunity / Animals / Membrane Lipids / Lipoprotein(a) / Mouse Model / Cell Proliferation / Membrane Protein / Anaplasma Phagocytophilum

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Endothelial-to-mesenchymal transition contributes to cardiac fibrosis

Extracellular Matrix / Bone Morphogenetic Proteins / Cell line / Cell Differentiation / Humans / Endothelial Cells / Mice / Chronic Disease / Animals / Heart Disease / Mouse Model / Endothelial cell / Transforming Growth Factor Beta / Mesenchymal Stromal Cells / Bone Marrow Cells / Transforming Growth Factor / Endothelial Cells / Mice / Chronic Disease / Animals / Heart Disease / Mouse Model / Endothelial cell / Transforming Growth Factor Beta / Mesenchymal Stromal Cells / Bone Marrow Cells / Transforming Growth Factor

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Mitochondrial bioenergetic deficit precedes Alzheimer\'s pathology in female mouse model of Alzheimer\'s disease

Immunohistochemistry / Oxidative Stress / Mitochondria / Multidisciplinary / Western blotting / Amyloid / Hippocampus / Brain / Humans / Mice / Female / Animals / Temporal Correlation / Amyloid Beta / Lipid peroxidation / Hydrogen Peroxide / Mitochondrial dysfunction / Mouse Model / Time Factors / Neurodegenerative Disease / Alzheimer Disease / Oxygen Consumption / Alcohol Dehydrogenase / Amyloid / Hippocampus / Brain / Humans / Mice / Female / Animals / Temporal Correlation / Amyloid Beta / Lipid peroxidation / Hydrogen Peroxide / Mitochondrial dysfunction / Mouse Model / Time Factors / Neurodegenerative Disease / Alzheimer Disease / Oxygen Consumption / Alcohol Dehydrogenase

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Recombinant Adeno-Associated Virus Serotype 9 Leads to Preferential Cardiac Transduction In Vivo

Genetics / Gene Therapy / Electrocardiography / Mice / Animals / Heart / Adeno-associated virus / Heart Disease / Clinical Sciences / Gene Delivery / Mouse Model / Skeletal Muscle / Circulation / Genetic Recombination / Gene Transfer / Serotyping / Heart / Adeno-associated virus / Heart Disease / Clinical Sciences / Gene Delivery / Mouse Model / Skeletal Muscle / Circulation / Genetic Recombination / Gene Transfer / Serotyping

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EFFICACY COMPARISON BETWEEN INTRAPORTAL AND SUBCAPSULAR ISLETS IN MURINE DIABETIC MODELS

Transplantation / Kidney / Blood Glucose / Mice / Female / Animals / Islet Transplantation / Mouse Model / Postoperative Period / Animals / Islet Transplantation / Mouse Model / Postoperative Period

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A viable mouse model of factor X deficiency provides evidence for maternal transfer of factor X

Genomic Imprinting / Humans / Mice / Female / Animals / Male / Haemostasis and Thrombosis / Fibrosis / Behavioral Animal Models / Clinical Sciences / Mouse Model / Genotype / Myocardium / Gene Targeting / Cardiomyopathies / Amino Acid Substitution Rates / Fetal death / Male / Haemostasis and Thrombosis / Fibrosis / Behavioral Animal Models / Clinical Sciences / Mouse Model / Genotype / Myocardium / Gene Targeting / Cardiomyopathies / Amino Acid Substitution Rates / Fetal death

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Cystatin C Deficiency Promotes Epidermal Dysplasia in K14-HPV16 Transgenic Mice

Engineering / Physics / Chemistry / Biology / Apoptosis / Medicine / Multidisciplinary / Transgenic Mice / HUMAN PAPILLOMAVIRUS / real time PCR / Humans / Mice / Female / Animals / Male / Active Control / Animal Model / Keratin / Hyperplasia / Epidermis / PLoS one / Mouse Model / cystatin C / Disease Progression / Cell Proliferation / Tumor Progression / Extracellular Matrix Proteins / Immunoblotting / Skin Neoplasms / Medicine / Multidisciplinary / Transgenic Mice / HUMAN PAPILLOMAVIRUS / real time PCR / Humans / Mice / Female / Animals / Male / Active Control / Animal Model / Keratin / Hyperplasia / Epidermis / PLoS one / Mouse Model / cystatin C / Disease Progression / Cell Proliferation / Tumor Progression / Extracellular Matrix Proteins / Immunoblotting / Skin Neoplasms

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FTY720 demonstrates promising preclinical activity for chronic lymphocytic leukemia and lymphoblastic leukemia/lymphoma

Apoptosis / Signal Transduction / Caspases / Cell line / Humans / Chronic Lymphocytic Leukemia / Mice / Animals / Blood / Organ Transplantation / Clinical Sciences / Mouse Model / Cysteine endopeptidases / B Lymphocytes / Okadaic acid / Sphingosine / Down-Regulation / Chronic Lymphocytic Leukemia / Mice / Animals / Blood / Organ Transplantation / Clinical Sciences / Mouse Model / Cysteine endopeptidases / B Lymphocytes / Okadaic acid / Sphingosine / Down-Regulation

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The Novel Deacetylase Inhibitor AR-42 Demonstrates Pre-Clinical Activity in B-Cell Malignancies In Vitro and In Vivo

Apoptosis / Multidisciplinary / Cell line / Humans / Chronic Lymphocytic Leukemia / PLoS one / Mouse Model / Time Dependent / Stromal Cells / MANTLE CELL LYMPHOMA / Acute Lymphoblastic Leukemia / Histone deacetylase inhibitors / PLoS one / Mouse Model / Time Dependent / Stromal Cells / MANTLE CELL LYMPHOMA / Acute Lymphoblastic Leukemia / Histone deacetylase inhibitors

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Non-viral delivery of the porphobilinogen deaminase cDNA into a mouse model of acute intermittent porphyria

Molecular Genetics / Transgenic Mice / Brain / Kidney / Liver / Mice / Female / Animals / Inborn errors of metabolism / Gene transfer techniques / Male / Liposomes / Luciferase / Lung / Enzyme / Clinical Sciences / Gene Delivery / Mouse Model / Blood Flow / Abdominal Pain / Polyethylenimine / Polyethyleneimine / Portal vein / Mice / Female / Animals / Inborn errors of metabolism / Gene transfer techniques / Male / Liposomes / Luciferase / Lung / Enzyme / Clinical Sciences / Gene Delivery / Mouse Model / Blood Flow / Abdominal Pain / Polyethylenimine / Polyethyleneimine / Portal vein

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Anti-recombinant V antigen serum promotes uptake of Yersinia enterocolitica serotype O8 by macrophages

Immunology / Medical Microbiology / Cell Culture / Mice / Animals / Male / Mouse Model / Phagocytosis / Amino Acid Profile / Rabbits / Recombinant Proteins / Outer Membrane Protein / Medical Microbiology and Immunology / Yersinia Enterocolitica / Serotyping / Male / Mouse Model / Phagocytosis / Amino Acid Profile / Rabbits / Recombinant Proteins / Outer Membrane Protein / Medical Microbiology and Immunology / Yersinia Enterocolitica / Serotyping

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Comparative efficacies of levofloxacin and ciprofloxacin against Streptococcus pneumoniae in a mouse model of experimental septicaemia

Statistical Analysis / Medical Microbiology / Acute kidney injury / Survival Analysis / Streptococcus pneumoniae / Drug Use / Humans / Mice / Animals / Microbial genetic and drug resistance / Mouse Model / Time Factors / Antimicrobial agents / Bacteremia / Microbial Sensitivity Tests / Ciprofloxacin / Lethal Dose / Ofloxacin / Levofloxacin / Drug Use / Humans / Mice / Animals / Microbial genetic and drug resistance / Mouse Model / Time Factors / Antimicrobial agents / Bacteremia / Microbial Sensitivity Tests / Ciprofloxacin / Lethal Dose / Ofloxacin / Levofloxacin

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Efficacy of systemic administration of SDF-1 in a model of vascular insufficiency: Support for an endothelium-dependent mechanism

Cardiovascular / Immunohistochemistry / Cornea / Animals / Vehicle dynamic control / Vascular endothelium / Behavioral Animal Models / Mouse Model / Rats / Endothelial cell / Blood Flow / DR-AR Model / Biological markers / Rat Model / Aorta / Cell Survival / Blood Vessel / Vascular Endothelial Growth Factor / Vascular endothelium / Behavioral Animal Models / Mouse Model / Rats / Endothelial cell / Blood Flow / DR-AR Model / Biological markers / Rat Model / Aorta / Cell Survival / Blood Vessel / Vascular Endothelial Growth Factor

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Fentanyl–trazodone–paracetamol triple drug combination: Multimodal analgesia in a mouse model of visceral pain

Pharmacology / Pain / Chronic Pain / Mice / Animals / Motor Coordination / Male / Synergy / Mouse Model / Acetic Acid / Acetaminophen / Mechanism of action / Opioid Receptor / Drug Interaction / Fixed Ratio / Fentanyl / Analgesics / Drug treatment / Motor Coordination / Male / Synergy / Mouse Model / Acetic Acid / Acetaminophen / Mechanism of action / Opioid Receptor / Drug Interaction / Fixed Ratio / Fentanyl / Analgesics / Drug treatment

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Cortical Glutamic Acid Decarboxylase 67 Deficiency Results in Lower Cannabinoid 1 Receptor Messenger RNA Expression: Implications for Schizophrenia

Schizophrenia / Working Memory / Gene expression / Prefrontal Cortex / In Situ Hybridization / Biological Sciences / Biological Psychiatry / Humans / Mice / Female / Animals / Male / Biological / Mouse Model / Glutamate decarboxylase / Biological Sciences / Biological Psychiatry / Humans / Mice / Female / Animals / Male / Biological / Mouse Model / Glutamate decarboxylase

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