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Influência do biofármaco DNA-hsp65 na lesão pulmonar induzida por bleomicina
Pulmonary fibrosis / Mice / Animals / Male / DNA vaccines / Bleomycin / Chaperonins / Bleomycin / Chaperonins
Characterization of Membrane Potential Dependency of Mitochondrial Ca2+ Uptake by an Improved Biophysical Model of Mitochondrial Ca2+ Uniporter
Biophysics / Calcium / Mitochondria / Multidisciplinary / Humans / Mice / Animals / Calcium channels / Organophosphorus Compounds / Non small cell carcinoma / PLoS one / Clinical Sciences / Theoretical Models / Mice / Animals / Calcium channels / Organophosphorus Compounds / Non small cell carcinoma / PLoS one / Clinical Sciences / Theoretical Models
Environmental influences on antibody-enhanced dengue disease outcomes
Medical Microbiology / Ecology / Dengue Virus / Mice / Female / Animals / Dengue / T lymphocytes / B Lymphocytes / Antibody dependent enhancement / Animals / Dengue / T lymphocytes / B Lymphocytes / Antibody dependent enhancement
Environmental influences on antibody-enhanced dengue disease outcomes
Medical Microbiology / Ecology / Dengue Virus / Mice / Female / Animals / Dengue / T lymphocytes / B Lymphocytes / Antibody dependent enhancement / Animals / Dengue / T lymphocytes / B Lymphocytes / Antibody dependent enhancement
Perinatal Maternal Administration of Lactobacillus paracasei NCC 2461 Prevents Allergic Inflammation in a Mouse Model of Birch Pollen Allergy
Immune response / Probiotics / Lactation / Multidisciplinary / Cell Culture / Toll like receptor signaling / Pregnancy / Pollen / Mice / Female / Animals / Lactobacillus / Drinking Water / Immunoglobulin E / Lung / PLoS one / mRna expression levels / Mouse Model / Betula / Mechanism of action / Cell Proliferation / Maternal-fetal exchange / immunoglobulin G / Bronchoalveolar lavage / Airway Inflammation / Toll like receptor signaling / Pregnancy / Pollen / Mice / Female / Animals / Lactobacillus / Drinking Water / Immunoglobulin E / Lung / PLoS one / mRna expression levels / Mouse Model / Betula / Mechanism of action / Cell Proliferation / Maternal-fetal exchange / immunoglobulin G / Bronchoalveolar lavage / Airway Inflammation
Neural progenitor genes
Genetics / Functional Analysis / Developmental Biology / Stem Cells / Gene regulation / Stem Cell / Stratification / Gene expression / In Situ Hybridization / Biological Sciences / Hematopoietic Stem Cells / Neural stem cell / Brain / Mice / Animals / Embryonic Stem Cell / Central Nervous System / Neurons / Developmental / Microarray Analysis / Subventricular Zone / Microarray Data / Hematopoietic Stem Cell / Gene expression profiling / Stem Cell / Stratification / Gene expression / In Situ Hybridization / Biological Sciences / Hematopoietic Stem Cells / Neural stem cell / Brain / Mice / Animals / Embryonic Stem Cell / Central Nervous System / Neurons / Developmental / Microarray Analysis / Subventricular Zone / Microarray Data / Hematopoietic Stem Cell / Gene expression profiling
Progressive Endoplasmic Reticulum Stress Contributes to Hepatocarcinogenesis in Fatty Acyl-CoA Oxidase 1–Deficient Mice
Endoplasmic Reticulum Stress / Humans / Liver / Mice / Animals / Endoplasmic Reticulum / Genotype / Hepatocytes / DNA binding proteins / Gene Expression Regulation / Endoplasmic Reticulum / Genotype / Hepatocytes / DNA binding proteins / Gene Expression Regulation
Ptychopetalum olacoides, a traditional Amazonian “nerve tonic”, possesses anticholinesterase activity
Pharmacology / Brazil / Medicinal Plants / Brain / Mice / Animals / Male / Acetylcholinesterase / Frontal Cortex / Central Nervous System / Memory Retrieval / Plant Roots / Cholinesterase inhibitors / Time Dependent / Side Effect / Cognitive Decline / Alzheimer Disease / Cognition disorders / Animals / Male / Acetylcholinesterase / Frontal Cortex / Central Nervous System / Memory Retrieval / Plant Roots / Cholinesterase inhibitors / Time Dependent / Side Effect / Cognitive Decline / Alzheimer Disease / Cognition disorders
Interferon-gamma is causatively involved in experimental inflammatory bowel disease in mice
Immunology / Disease susceptibility / Peroxidase / Mice / Weight Loss / Animals / Clinical / Colitis / Colon / Interferon gamma / Animals / Clinical / Colitis / Colon / Interferon gamma
Profibrogenic transforming growth factor-β/activin receptor-like kinase 5 signaling via connective tissue growth factor expression in hepatocytes
Hepatology / Signal Transduction / Humans / Liver Cirrhosis / Mice / Female / Animals / Male / Clinical Sciences / Hepatocytes / Transforming Growth Factor Beta / Antiviral Agents / Interferon gamma / Transforming Growth Factor / Female / Animals / Male / Clinical Sciences / Hepatocytes / Transforming Growth Factor Beta / Antiviral Agents / Interferon gamma / Transforming Growth Factor
A hydrogel derived from decellularized dermal extracellular matrix
Viscoelasticity / Biomaterials / Kinetics / Rheology / Hydrogels / Multidisciplinary / Extracellular Matrix / Elasticity / Cell line / Mice / Animals / Hydrogel / Viscosity / Scaffold / Surface topography / Cell Viability / T cells / Glycosaminoglycans / Surface Properties / Dermis / Biocompatible Materials / Cell Survival / Multidisciplinary / Extracellular Matrix / Elasticity / Cell line / Mice / Animals / Hydrogel / Viscosity / Scaffold / Surface topography / Cell Viability / T cells / Glycosaminoglycans / Surface Properties / Dermis / Biocompatible Materials / Cell Survival
Biologically Active Dibenzofurans fromPilidiostigma glabrum, an Endemic Australian Myrtaceae
Natural Products / Australia / Macrophages / Biological Sciences / Mice / Nitric oxide / Animals / Myrtaceae / Anti-inflammatory agents / CHEMICAL SCIENCES / Anti-Bacterial Agents / Tumor necrosis factor-alpha / Structure activity Relationship / Molecular Structure / Plant Leaves / Nitric oxide / Animals / Myrtaceae / Anti-inflammatory agents / CHEMICAL SCIENCES / Anti-Bacterial Agents / Tumor necrosis factor-alpha / Structure activity Relationship / Molecular Structure / Plant Leaves
Leishmania amazonensis: Biological and biochemical characterization of ecto-nucleoside triphosphate diphosphohydrolase activities
Microbiology / Flow Cytometry / Western blotting / Experimental parasitology / Humans / Mice / Female / Animals / Enzyme / Experimental / Western blot / Cutaneous Leishmaniasis / Veterinary Sciences / Mouse Peritoneal-Macrophages / Adenosine Triphosphate / Adenosine monophosphate / Adenosine Diphosphate / Mice / Female / Animals / Enzyme / Experimental / Western blot / Cutaneous Leishmaniasis / Veterinary Sciences / Mouse Peritoneal-Macrophages / Adenosine Triphosphate / Adenosine monophosphate / Adenosine Diphosphate
Hierarchical scaffolds via combined macro- and micro-phase separation
Thermodynamics / Biomaterials / Tissue Engineering / Scanning Electron Microscopy / Self Assembly / Nanotechnology / Polymers / Atomic Force Microscopy / Multidisciplinary / Block Copolymer / Surface modification / Mice / Animals / Thin Film / Temperature / Dimensional / Phase Separation / Biological Process / Copolymer / Nanotechnology / Polymers / Atomic Force Microscopy / Multidisciplinary / Block Copolymer / Surface modification / Mice / Animals / Thin Film / Temperature / Dimensional / Phase Separation / Biological Process / Copolymer
PARP-1 Inhibition Increases Mitochondrial Metabolism through SIRT1 Activation
Skeletal muscle biology / Oxidative Stress / Mitochondria / DNA damage / Energy Metabolism / RNA interference / Mice / Animals / Cell Death / Phenotype / Brown Adipose Tissue / NAD / Sirtuin / Biochemistry and cell biology / RNA interference / Mice / Animals / Cell Death / Phenotype / Brown Adipose Tissue / NAD / Sirtuin / Biochemistry and cell biology
PARP1 Inhibition Increases Mitochondrial Metabolism through SIRT1 Activation
Skeletal muscle biology / Oxidative Stress / Mitochondria / DNA damage / Energy Metabolism / RNA interference / Mice / Animals / Cell Death / Phenotype / Brown Adipose Tissue / NAD / Sirtuin / Biochemistry and cell biology / RNA interference / Mice / Animals / Cell Death / Phenotype / Brown Adipose Tissue / NAD / Sirtuin / Biochemistry and cell biology
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