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Mycolactones: immunosuppressive and cytotoxic polyketides produced by aquatic mycobacteria
Biological Sciences / Humans / Mice / Animals / Natural Product / Fishes / Anura / CHEMICAL SCIENCES / Water Microbiology / Mycobacterium Ulcerans / Structure activity Relationship / Lactones / Cytotoxins / Molecular Structure / Macrolides / Fishes / Anura / CHEMICAL SCIENCES / Water Microbiology / Mycobacterium Ulcerans / Structure activity Relationship / Lactones / Cytotoxins / Molecular Structure / Macrolides
The complex portal - an encyclopaedia of macromolecular complexes
Biological Sciences / Environmental Sciences / Humans / Mice / Animals / Nucleic Acids / Proteins / Protein Binding / Internet / Nucleic Acids / Proteins / Protein Binding / Internet
Characterization of a Designed Vascular Endothelial Growth Factor Receptor Antagonist Helical Peptide with Antiangiogenic Activity in Vivo
Organic Chemistry / Water / Medicinal Chemistry / Magnetic Resonance Spectroscopy / Signal Transduction / Humans / Endothelial Cells / Circular Dichroism / Mice / Animals / Peptides / Protein Secondary Structure Prediction / Medicinal / Cell Proliferation / Cell Survival / Humans / Endothelial Cells / Circular Dichroism / Mice / Animals / Peptides / Protein Secondary Structure Prediction / Medicinal / Cell Proliferation / Cell Survival
Poly(lactic acid-glycolic acid) nanoparticles markedly improve immunological protection provided by peptide P10 against murine paracoccidioidomycosis
British / Nanobiotechnology / Treatment / Nanoparticle / Nanoparticles / Nanotechnology / Poly (lactic acid) / Mice / Animals / Male / Biodegradable Polymers / Glycoproteins / Combination drug therapy / Drug Carriers / Lactic Acid / Delayed-Action Preparations / Paracoccidioides / Nanotechnology / Poly (lactic acid) / Mice / Animals / Male / Biodegradable Polymers / Glycoproteins / Combination drug therapy / Drug Carriers / Lactic Acid / Delayed-Action Preparations / Paracoccidioides
Therapeutic DNA Vaccine Encoding Peptide P10 against Experimental Paracoccidioidomycosis
Biological Sciences / Mice / Animals / Male / Immunotherapy / DNA vaccines / Plasmids / Glycoproteins / Lung / Paracoccidioides / DNA vaccines / Plasmids / Glycoproteins / Lung / Paracoccidioides
Effects of Anabaena spiroides (cyanobacteria) aqueous extracts on the acetylcholinesterase activity of aquatic species
Algorithms / Kinetics / Aging / Biological Sciences / Environmental Sciences / Mice / Animals / Fishes / Acetylcholinesterase / EELS / Cholinesterase inhibitors / Brachyura / CHEMICAL SCIENCES / Plant extracts / Malathion / Environmental Toxicology and Chemistry / Anabaena / Forensic Chemistry and Toxicology / Aqueous Extract / Mice / Animals / Fishes / Acetylcholinesterase / EELS / Cholinesterase inhibitors / Brachyura / CHEMICAL SCIENCES / Plant extracts / Malathion / Environmental Toxicology and Chemistry / Anabaena / Forensic Chemistry and Toxicology / Aqueous Extract
Prostate targeting: PSP94 gene promoter/enhancer region directed prostate tissue-specific expression in a transgenic mouse prostate cancer model
Clinical Trial / Gene Therapy / Immunohistochemistry / Prostate Cancer / Cell Culture / Transgenic Mice / Biological Sciences / Mice / Animals / Male / Gene Targeting / Disease Progression / Amino Acid Profile / Transgenic Mouse Technology / Tumor Progression / Tissue Specificity / Transgenic Mice / Biological Sciences / Mice / Animals / Male / Gene Targeting / Disease Progression / Amino Acid Profile / Transgenic Mouse Technology / Tumor Progression / Tissue Specificity
Characterization of a Designed Vascular Endothelial Growth Factor Receptor Antagonist Helical Peptide with Antiangiogenic Activity in Vivo
Organic Chemistry / Water / Medicinal Chemistry / Magnetic Resonance Spectroscopy / Signal Transduction / Humans / Endothelial Cells / Circular Dichroism / Mice / Animals / Peptides / Protein Secondary Structure Prediction / Medicinal / Cell Proliferation / Cell Survival / Humans / Endothelial Cells / Circular Dichroism / Mice / Animals / Peptides / Protein Secondary Structure Prediction / Medicinal / Cell Proliferation / Cell Survival
Bone sialoprotein deficiency impairs osteoclastogenesis and mineral resorption in vitro
Engineering / Minerals / Apoptosis / Biological Sciences / Spleen / In Vitro / Cell Differentiation / Humans / Mice / Bone / Animals / Osteoclasts / Osteopontin / Bone Mineral Density / Dentin / Biological markers / Osteogenesis / Cell Proliferation / BSP / Durapatite / Somatic Cell Count / Recombinant Proteins / Resorption / Bone Resorption / Gene expression profiling / In Vitro / Cell Differentiation / Humans / Mice / Bone / Animals / Osteoclasts / Osteopontin / Bone Mineral Density / Dentin / Biological markers / Osteogenesis / Cell Proliferation / BSP / Durapatite / Somatic Cell Count / Recombinant Proteins / Resorption / Bone Resorption / Gene expression profiling
RGD: A comparative genomics platform
Obesity / Human / Humans / Metabolic diseases / Mice / Animals / Genome / Phenotype / Online Systems / Rats / Neoplasms / Quantitative Trait Loci / Cardiovascular Diseases / Human Genomics / Nervous System Diseases / Animals / Genome / Phenotype / Online Systems / Rats / Neoplasms / Quantitative Trait Loci / Cardiovascular Diseases / Human Genomics / Nervous System Diseases
Vascular Endothelial Growth Factor-B Promotes In Vivo Angiogenesis
Cell Division / Signal Transduction / Capillaries / Collagen / Ischemia / Mice / Nitric oxide / Female / Animals / Male / Phosphorylation / Clinical Sciences / Mouse Model / Proteoglycans / Nitric Oxide Synthase / Western blot / Circulation / Matrix Metalloproteinases / Somatic Cell Count / Biological Assay / Methyl Ester / Neutralizing antibodies / Vascular Endothelial Growth Factor / Vascular endothelial growth factor receptor / Laminin / Mice / Nitric oxide / Female / Animals / Male / Phosphorylation / Clinical Sciences / Mouse Model / Proteoglycans / Nitric Oxide Synthase / Western blot / Circulation / Matrix Metalloproteinases / Somatic Cell Count / Biological Assay / Methyl Ester / Neutralizing antibodies / Vascular Endothelial Growth Factor / Vascular endothelial growth factor receptor / Laminin
Steatosis-Induced Proteomic Changes in Liver Mitochondria Evidenced by Two-Dimensional Differential In-Gel Electrophoresis
Mass Spectrometry / Proteomics / Oxidative Stress / Mitochondria / Biological Sciences / Liver / Fatty acids / Mice / Animals / Male / Lipid peroxidation / High Pressure Liquid Chromatography / CHEMICAL SCIENCES / Fatty Liver / Hepatocytes / Peroxisomes / Gel electrophoresis / Two-Dimensional Gel Electrophoresis / Proteome / Adenosine Triphosphate / Liver / Fatty acids / Mice / Animals / Male / Lipid peroxidation / High Pressure Liquid Chromatography / CHEMICAL SCIENCES / Fatty Liver / Hepatocytes / Peroxisomes / Gel electrophoresis / Two-Dimensional Gel Electrophoresis / Proteome / Adenosine Triphosphate
Periplasmic Cu,Zn superoxide dismutase and cytoplasmic Dps concur in protecting Salmonella enterica serovar Typhimurium from extracellular reactive oxygen species
Biological Sciences / Mutation / Bacterial resistance / Reactive Oxygen Species / Mice / Animals / Salmonella Typhimurium / Physical sciences / Detoxification / Superoxide Dismutase / NADPH oxidase / Hydrogen Peroxide / Antioxidant enzyme / Phagocytosis / Oxidative Damage / Cytoplasm / DNA binding proteins / Superoxides / Respiratory Burst / Biochemistry and cell biology / Animals / Salmonella Typhimurium / Physical sciences / Detoxification / Superoxide Dismutase / NADPH oxidase / Hydrogen Peroxide / Antioxidant enzyme / Phagocytosis / Oxidative Damage / Cytoplasm / DNA binding proteins / Superoxides / Respiratory Burst / Biochemistry and cell biology
HDAC Inhibitors Correct Frataxin Deficiency in a Friedreich Ataxia Mouse Model
Enzyme Inhibitors / Gene expression / Multidisciplinary / Cerebellum / Mice / Animals / Histone Modification / PLoS one / Chromatin / Introns / Histones / Mouse Model / Microarray Analysis / Myocardium / Chromatin Immunoprecipitation / Western blot / Acetylation / Neurodegenerative Disease / Histone deacetylase inhibitor / Nervous System / Autosomal Recessive / Acute Toxicity / Cardiac Disease / Friedreich Ataxia / Gene expression profiling / Histone deacetylase inhibitors / Iron binding proteins / Animals / Histone Modification / PLoS one / Chromatin / Introns / Histones / Mouse Model / Microarray Analysis / Myocardium / Chromatin Immunoprecipitation / Western blot / Acetylation / Neurodegenerative Disease / Histone deacetylase inhibitor / Nervous System / Autosomal Recessive / Acute Toxicity / Cardiac Disease / Friedreich Ataxia / Gene expression profiling / Histone deacetylase inhibitors / Iron binding proteins
Experimental selection of long-term intracellular mycobacteria
Microbiology / Medical Microbiology / Macrophages / Cellular microbiology / Mycobacterium / Mice / Female / Animals / Glycolipids / Mycobacterium bovis / Mice / Female / Animals / Glycolipids / Mycobacterium bovis
Hyperleucinemia causes hippocampal retromer deficiency linking diabetes to Alzheimer\'s disease
Neurobiology Of Disease / Hippocampus / Humans / Mice / Animals / Male / Leptin / Clinical Sciences / Neuroblastoma / Analysis of Variance / Disease Progression / Glucose Tolerance Test / Type 2 Diabetes Mellitus / Alzheimer Disease / Neurosciences / Enzyme Linked Immunosorbent Assay / Male / Leptin / Clinical Sciences / Neuroblastoma / Analysis of Variance / Disease Progression / Glucose Tolerance Test / Type 2 Diabetes Mellitus / Alzheimer Disease / Neurosciences / Enzyme Linked Immunosorbent Assay
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