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Mice
Mice
NMDA Preconditioning Attenuates Cortical and Hippocampal Seizures Induced by Intracerebroventricular Quinolinic Acid Infusion
Hippocampus / Cerebral Cortex / Mice / Animals / Male / Neurotoxicity / Brain Waves / Clinical Sciences / Seizures / Neurosciences / Biochemistry and cell biology / Neuroprotective Agents / Neurotoxicity / Brain Waves / Clinical Sciences / Seizures / Neurosciences / Biochemistry and cell biology / Neuroprotective Agents
Nedd9 restrains renal cystogenesis in Pkd1-/- mice
Multidisciplinary / Kidney / Mice / Female / Animals / Male / Calcium Signaling / Epithelial cells / Primary Cell Culture / Cilia / Triazoles / Male / Calcium Signaling / Epithelial cells / Primary Cell Culture / Cilia / Triazoles
Rapamycin doses sufficient to extend lifespan do not compromise muscle mitochondrial content or endurance
Skeletal muscle biology / Aging / Mice / Animals / Male / Sirolimus / Gene Expression Regulation / Physical Endurance / Motor activity / Sirolimus / Gene Expression Regulation / Physical Endurance / Motor activity
Oxidative Phosphorylation, Ca2+ Transport, and Fatty Acid-induced Uncoupling in Malaria Parasites Mitochondria
Calcium / Membrane Proteins / Mitochondria / Biological Chemistry / Ion Channels / Biological Sciences / Fatty acids / Mice / Animals / Male / Biological / CHEMICAL SCIENCES / Oxidative phosphorylation / Fatty Acid / Ion Transport / Plasmodium berghei / Mitochondrial Proteins / Biological Sciences / Fatty acids / Mice / Animals / Male / Biological / CHEMICAL SCIENCES / Oxidative phosphorylation / Fatty Acid / Ion Transport / Plasmodium berghei / Mitochondrial Proteins
Transgenic expression of human acetylcholinesterase induces progressive cognitive deterioration in mice
Aging / Molecular Mechanics / Transgenic Mice / Biological Sciences / Learning and Memory / Humans / Mice / Animals / Cell Death / Acetylcholinesterase / Open Field / Central Nervous System / Animal Model / Acetylcholine / Spatial Learning / Neurons / Cholinesterase inhibitors / Structural Change / Enzyme / Locomotor Activity / Neuromuscular Junction / Transgene Expression / Cognition disorders / Water maze / Humans / Mice / Animals / Cell Death / Acetylcholinesterase / Open Field / Central Nervous System / Animal Model / Acetylcholine / Spatial Learning / Neurons / Cholinesterase inhibitors / Structural Change / Enzyme / Locomotor Activity / Neuromuscular Junction / Transgene Expression / Cognition disorders / Water maze
MicroRNA-132 Potentiates Cholinergic Anti-Inflammatory Signaling by Targeting Acetylcholinesterase
Immunology / MicroRNA / Inflammation / Macrophages / Signal Transduction / Cell line / Humans / Mice / Immunity / Female / Animals / Acetylcholinesterase / Acetylcholine / microRNAs / Lipopolysaccharides / Base Sequence / Oligonucleotides / Bone Marrow Cells / Down-Regulation / Cell line / Humans / Mice / Immunity / Female / Animals / Acetylcholinesterase / Acetylcholine / microRNAs / Lipopolysaccharides / Base Sequence / Oligonucleotides / Bone Marrow Cells / Down-Regulation
Lactoferrin decreases LPS-induced mitochondrial dysfunction in cultured cells and in animal endotoxemia model
Immune response / Oxidative Stress / Mitochondria / DNA damage / Innate immunity / Lipopolysaccharide / Humans / Reactive Oxygen Species / Mice / Animals / Siderophores / P-glycoprotein / Iron / Innate / Hydrogen Peroxide / Mitochondrial dysfunction / Lipopolysaccharides / ENDOTOXEMIA / Epithelial cells / Monocytes / Oxidative Damage / Deferoxamine / Lipopolysaccharide / Humans / Reactive Oxygen Species / Mice / Animals / Siderophores / P-glycoprotein / Iron / Innate / Hydrogen Peroxide / Mitochondrial dysfunction / Lipopolysaccharides / ENDOTOXEMIA / Epithelial cells / Monocytes / Oxidative Damage / Deferoxamine
Lactoferrin decreases LPS-induced mitochondrial dysfunction in cultured cells and in animal endotoxemia model
Immune response / Oxidative Stress / Mitochondria / DNA damage / Innate immunity / Lipopolysaccharide / Humans / Reactive Oxygen Species / Mice / Animals / Siderophores / P-glycoprotein / Iron / Innate / Hydrogen Peroxide / Mitochondrial dysfunction / Lipopolysaccharides / ENDOTOXEMIA / Epithelial cells / Monocytes / Oxidative Damage / Deferoxamine / Lipopolysaccharide / Humans / Reactive Oxygen Species / Mice / Animals / Siderophores / P-glycoprotein / Iron / Innate / Hydrogen Peroxide / Mitochondrial dysfunction / Lipopolysaccharides / ENDOTOXEMIA / Epithelial cells / Monocytes / Oxidative Damage / Deferoxamine
Myeloid mineralocorticoid receptor deficiency inhibits aortic constriction-induced cardiac hypertrophy in mice
Macrophages / Multidisciplinary / Reactive Oxygen Species / Mice / Animals / Male / PLoS one / Gene Expression Regulation / Male / PLoS one / Gene Expression Regulation
Transcriptional competence in pluripotency
Induced Pluripotent Stem Cells (I Psc) / Cellular Reprogramming / Transcription Factors / Biological Sciences / Mice / Animals / Embryonic Stem Cells / Chromatin / Animals / Embryonic Stem Cells / Chromatin
‘Working’ cardiomyocytes exhibiting plateau action potentials from human placenta-derived extraembryonic mesodermal cells
Immunohistochemistry / Stem Cell / Heart Failure / Cell Differentiation / Humans / Placenta / Mice / Female / Animals / Embryonic Stem Cell / Male / Mesenchymal Stem Cell / Cell Transplantation / Clinical Sciences / Action potential / Connexin / Primary Culture / Action Potentials / Sex Chromosome / Clinical Application / Troponin I / Bone Marrow Cells / Biochemistry and cell biology / Gene expression profiling / Placenta / Mice / Female / Animals / Embryonic Stem Cell / Male / Mesenchymal Stem Cell / Cell Transplantation / Clinical Sciences / Action potential / Connexin / Primary Culture / Action Potentials / Sex Chromosome / Clinical Application / Troponin I / Bone Marrow Cells / Biochemistry and cell biology / Gene expression profiling
Leishmania amazonensis: Biological and biochemical characterization of ecto-nucleoside triphosphate diphosphohydrolase activities
Microbiology / Flow Cytometry / Western blotting / Experimental parasitology / Humans / Mice / Female / Animals / Enzyme / Experimental / Western blot / Cutaneous Leishmaniasis / Veterinary Sciences / Mouse Peritoneal-Macrophages / Adenosine Triphosphate / Adenosine monophosphate / Adenosine Diphosphate / Mice / Female / Animals / Enzyme / Experimental / Western blot / Cutaneous Leishmaniasis / Veterinary Sciences / Mouse Peritoneal-Macrophages / Adenosine Triphosphate / Adenosine monophosphate / Adenosine Diphosphate
H3 Relaxin Demonstrates Antifibrotic Properties via the RXFP1 Receptor
Biochemistry / Humans / Collagen / Mice / G protein-coupled receptors / Animals / Male / Fibrosis / Rats / Matrix Metalloproteinases / Transforming Growth Factor Beta / Human Fibroblasts / Heart Ventricles / Biochemistry and cell biology / Relaxin / Animals / Male / Fibrosis / Rats / Matrix Metalloproteinases / Transforming Growth Factor Beta / Human Fibroblasts / Heart Ventricles / Biochemistry and cell biology / Relaxin
Serelaxin is a more efficacious antifibrotic than enalapril in an experimental model of heart disease
Treatment Outcome / Enalapril / Hypertension / Mice / Blood Pressure / Renin Angiotensin Aldosterone System / Animals / Male / Heart / Fibrosis / Clinical Sciences / Myocardium / Recombinant Proteins / Relaxin / Heart Diseases / Renin Angiotensin Aldosterone System / Animals / Male / Heart / Fibrosis / Clinical Sciences / Myocardium / Recombinant Proteins / Relaxin / Heart Diseases
Molecular Characterization of NAD+-Dependent DNA Ligase from Wolbachia Endosymbiont of Lymphatic Filarial Parasite Brugia malayi
Engineering / Physics / Chemistry / Catalysis / Biology / Confocal Microscopy / Medicine / Multidisciplinary / Western blotting / Phylogeny / Circular Dichroism / Mice / Female / Animals / Male / Wolbachia / PLoS one / Amino Acid Sequence / Recombinant Proteins / Immunoblotting / Confocal Microscopy / Medicine / Multidisciplinary / Western blotting / Phylogeny / Circular Dichroism / Mice / Female / Animals / Male / Wolbachia / PLoS one / Amino Acid Sequence / Recombinant Proteins / Immunoblotting
The protective effects of guaraná extract (Paullinia cupana) on fibroblast NIH-3T3 cells exposed to sodium nitroprusside
Oxidative Stress / DNA damage / Antioxidants / Caffeine / Mice / Nitric oxide / Animals / High Pressure Liquid Chromatography / Comet Assay / Plant extracts / Food Sciences / Human Fibroblasts / Food and Chemical Toxicology / Catechin / Theobromine / Nitric oxide / Animals / High Pressure Liquid Chromatography / Comet Assay / Plant extracts / Food Sciences / Human Fibroblasts / Food and Chemical Toxicology / Catechin / Theobromine
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