Hyperalgesia

Massage Reduces Pain Perception and Hyperalgesia in Experimental Muscle Pain: A Randomized, Controlled Trial

Pain / Skeletal muscle biology / Treatment / Treatment Outcome / Manual Therapy / Pain Management / Massage / Humans / Female / Male / Pain Perception / Exercise / Adult / Analysis of Variance / Randomized Controlled Trial / Pain Measurement / Wrist / Hyperalgesia / Pain Threshold / Control Group / Delayed onset muscle soreness / Pain Management / Massage / Humans / Female / Male / Pain Perception / Exercise / Adult / Analysis of Variance / Randomized Controlled Trial / Pain Measurement / Wrist / Hyperalgesia / Pain Threshold / Control Group / Delayed onset muscle soreness

Transient receptor potential ankyrin-1 participates in visceral hyperalgesia following experimental colitis

Psychology / Cognitive Science / Transient receptor potential channels / Animals / Calcium channels / Male / Electromyography / Colitis / Dorsal root ganglia / Rats / Gastrointestinal motility / Wistar Rats / Colon / Neurosciences / Pain Measurement / Inflammatory Pain / Hyperalgesia / Pain Threshold / Male / Electromyography / Colitis / Dorsal root ganglia / Rats / Gastrointestinal motility / Wistar Rats / Colon / Neurosciences / Pain Measurement / Inflammatory Pain / Hyperalgesia / Pain Threshold

Alcohol consumption enhances antiretroviral painful peripheral neuropathy by mitochondrial mechanisms

Psychology / Cognitive Science / Drug interactions / Mitochondria / Animals / Male / Ethanol / Rats / Neurosciences / Hyperalgesia / Male / Ethanol / Rats / Neurosciences / Hyperalgesia

Tingenone, a pentacyclic triterpene, induces peripheral antinociception due to opioidergic activation

Complementary and Alternative Medicine / Plant Biology / Mice / Animals / Male / Analgesics / Hyperalgesia / Triterpenes / Maytenus / Analgesics / Hyperalgesia / Triterpenes / Maytenus

JNJ-20788560 [9-(8-Azabicyclo[3.2.1]oct-3-ylidene)-9H-xanthene-3-carboxylic Acid Diethylamide], a Selective Delta Opioid Receptor Agonist, Is a Potent and Efficacious Antihyperalgesic Agent That Does Not Produce Respiratory Depression, Pharmacologic Tolerance, or Physical Dependence

Pharmacology / Mice / Animals / Male / Self-administration / Rats / Gastrointestinal motility / Wistar Rats / Seizures / Opioid Receptor / Pain Measurement / Substance-Related Disorders / Hyperalgesia / *Hot Temperature / Drug Tolerance / Rats / Gastrointestinal motility / Wistar Rats / Seizures / Opioid Receptor / Pain Measurement / Substance-Related Disorders / Hyperalgesia / *Hot Temperature / Drug Tolerance

Gabapentin Prevents Delayed and Long-lasting Hyperalgesia Induced by Fentanyl in Rats

Anesthesiology / TIME / Amines / Animals / Male / Clinical Sciences / Rats / Time / Fentanyl / Pain Measurement / Hyperalgesia / Gamma-Aminobutyric Acid / Clinical Sciences / Rats / Time / Fentanyl / Pain Measurement / Hyperalgesia / Gamma-Aminobutyric Acid

Prostaglandin E 2 glycerol ester, an endogenous COX2 metabolite of 2-arachidonoylglycerol, induces hyperalgesia and modulates NFκB activity

Pain / Mass Spectrometry / British / Macrophages / Cell line / Mice / Animals / Male / NF-kappa B / Rats / Endocannabinoids / Pain Measurement / Hyperalgesia / *Hot Temperature / Prostaglandin E2 / Mice / Animals / Male / NF-kappa B / Rats / Endocannabinoids / Pain Measurement / Hyperalgesia / *Hot Temperature / Prostaglandin E2

Olive (Olea europaea L.) leaf extract elicits antinociceptive activity, potentiates morphine analgesia and suppresses morphine hyperalgesia in rats

Pain / Complementary and Alternative Medicine / Traditional Medicine / Plant Biology / Ethnopharmacology / Olea europaea / Animals / Male / Analgesia / Morphine / Plant extracts / Rats / Wistar Rats / Pain Measurement / Olea / Analgesics / Hyperalgesia / Pain Threshold / Calcium Channel Blocker / Plant Leaves / Formalin Test / Olea europaea / Animals / Male / Analgesia / Morphine / Plant extracts / Rats / Wistar Rats / Pain Measurement / Olea / Analgesics / Hyperalgesia / Pain Threshold / Calcium Channel Blocker / Plant Leaves / Formalin Test

Central Sensitization: A Generator of Pain Hypersensitivity by Central Neural Plasticity

Pain / Humans / Neuropathic pain / Animals / Neuronal Plasticity / Central Nervous System / Synaptic Transmission / Neural plasticity / Nervous System / Action potential / Central Sensitization / Inflammatory Pain / Hyperalgesia / Pain Threshold / Nociceptors / Central Nervous System / Synaptic Transmission / Neural plasticity / Nervous System / Action potential / Central Sensitization / Inflammatory Pain / Hyperalgesia / Pain Threshold / Nociceptors

Prior exposure to glucocorticoids potentiates lipopolysaccharide induced mechanical allodynia and spinal neuroinflammation

Psychology / Immunology / Inflammation / Inflammatory Immune Response / Lipopolysaccharide / Animals / Spinal Cord / Corticosterone / Male / Lipopolysaccharides / Rats / Neurosciences / Pain Measurement / Glucocorticoids / Hyperalgesia / Pain Threshold / Interleukin / Animals / Spinal Cord / Corticosterone / Male / Lipopolysaccharides / Rats / Neurosciences / Pain Measurement / Glucocorticoids / Hyperalgesia / Pain Threshold / Interleukin

Vaginal hyperalgesia in a rat model of endometriosis

Psychology / Cognitive Science / Catheterization / Adipose tissue / Female / Animals / Vagina / Pressure / Rats / Endometriosis / Rat Model / Uterus / Neurosciences / Hyperalgesia / Animals / Vagina / Pressure / Rats / Endometriosis / Rat Model / Uterus / Neurosciences / Hyperalgesia

Spinal transient receptor potential ankyrin 1 channel contributes to central pain hypersensitivity in various pathophysiological conditions in the rat

Pain / Sleep Deprivation / Transient receptor potential channels / Animals / Calcium channels / Spinal Cord / Male / Capsaicin / Rats / Analysis of Variance / Wistar Rats / Rem Sleep / Formaldehyde / Cholecystokinin / Pain Measurement / Hyperalgesia / Dorsal Horn / Experimental Model / Spinal Cord / Male / Capsaicin / Rats / Analysis of Variance / Wistar Rats / Rem Sleep / Formaldehyde / Cholecystokinin / Pain Measurement / Hyperalgesia / Dorsal Horn / Experimental Model

Identification of 2-hydroxymethyl-4-[5-(4-methoxyphenyl)-3-trifluoromethyl-pyrazol-1-yl]-N-propionylbenzenesulfonamide sodium as a potential COX-2 inhibitor for oral and parenteral administration

Organic Chemistry / Enzyme Inhibitors / Prodrugs / Humans / Animals / Male / Solubility / Rats / Edema / Fever / Foot / Wistar Rats / Carrageenan / Water soluble polymers / Bioorganic and medicinal Chemistry / Structure activity Relationship / Hyperalgesia / Endotoxins / Molecular Structure / Male / Solubility / Rats / Edema / Fever / Foot / Wistar Rats / Carrageenan / Water soluble polymers / Bioorganic and medicinal Chemistry / Structure activity Relationship / Hyperalgesia / Endotoxins / Molecular Structure

Poly(ADP-Ribose) Polymerase Inhibition Alleviates Experimental Diabetic Sensory Neuropathy

Diabetes / Immunohistochemistry / Oxidative Stress / Apoptosis / Blood Glucose / Animals / Male / Neurons / Rats / Body Weight / Wistar Rats / Quinolines / Hyperalgesia / Tyrosine / Animals / Male / Neurons / Rats / Body Weight / Wistar Rats / Quinolines / Hyperalgesia / Tyrosine

Linalool and linalool complexed in β-cyclodextrin produce anti-hyperalgesic activity and increase Fos protein expression in animal model for fibromyalgia

Mice / Fibromyalgia / Animals / Male / Combination drug therapy / Monoterpenes / Pain Measurement / Hyperalgesia / Gene Expression Regulation / Monoterpenes / Pain Measurement / Hyperalgesia / Gene Expression Regulation

Trigeminal antihyperalgesic effect of intranasal carbon dioxide

Animal Behavior / Carbon Dioxide / Life Sciences / Animals / Male / Capsaicin / Rats / Voltage-Gated Sodium Channels / Intranasal Administration / Hydrogen-Ion Concentration / Trigeminal / Trigeminal Nerve / Pain Measurement / Hyperalgesia / Nasal Mucosa / Biochemistry and cell biology / Capsaicin / Rats / Voltage-Gated Sodium Channels / Intranasal Administration / Hydrogen-Ion Concentration / Trigeminal / Trigeminal Nerve / Pain Measurement / Hyperalgesia / Nasal Mucosa / Biochemistry and cell biology
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