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Hyperalgesia
Hyperalgesia
Massage Reduces Pain Perception and Hyperalgesia in Experimental Muscle Pain: A Randomized, Controlled Trial
Pain / Skeletal muscle biology / Treatment Outcome / Manual Therapy / Pain Management / Massage / Humans / Female / Male / Pain Perception / Exercise / Adult / Analysis of Variance / Randomized Controlled Trial / Pain Measurement / Wrist / Hyperalgesia / Pain Threshold / Control Group / Delayed onset muscle soreness / Massage / Humans / Female / Male / Pain Perception / Exercise / Adult / Analysis of Variance / Randomized Controlled Trial / Pain Measurement / Wrist / Hyperalgesia / Pain Threshold / Control Group / Delayed onset muscle soreness
Hyperalgesia, nerve infiltration and nerve growth factor expression in deep adenomyotic nodules, peritoneal and ovarian endometriosis
Immunohistochemistry / Humans / Tyrosine Kinase Receptor / Female / Human reproduction / Adult / Endometriosis / Group / Physical examination / Nervous System / Nerve Growth Factor / Hyperalgesia / Adult / Endometriosis / Group / Physical examination / Nervous System / Nerve Growth Factor / Hyperalgesia
Lipopolysaccharide-induced hyperalgesia of intracranial capsaicin sensitive afferents in conscious rats
Animal Behavior / Pain / Lipopolysaccharide / Brain / Animals / Male / Capsaicin / Immune system / Lipopolysaccharides / Rats / Grooming / Wistar Rats / Exploratory Behavior / Trigeminal / Hyperalgesia / Male / Capsaicin / Immune system / Lipopolysaccharides / Rats / Grooming / Wistar Rats / Exploratory Behavior / Trigeminal / Hyperalgesia
TRPA1 contributes to capsaicin-induced facial cold hyperalgesia in rats
Dentistry / Animal Behavior / Face / Animals / Male / Electromyography / Synaptic Transmission / Neurons / Capsaicin / Rats / Reflex / Hyperalgesia / *Hot Temperature / Electromyography / Synaptic Transmission / Neurons / Capsaicin / Rats / Reflex / Hyperalgesia / *Hot Temperature
Low-Dose Lidocaine Reduces Secondary Hyperalgesia by a Central Mode of Action
Pain / Humans / Low Dose / Neuropathic pain / Female / Male / Central Nervous System / The / Capsaicin / Middle Aged / Mode of action / Adult / Sodium channel / Lidocaine / Mechanism of action / Axons / Neurosciences / Pain Measurement / Time Course / Hyperalgesia / Laser Doppler Flowmetry / Male / Central Nervous System / The / Capsaicin / Middle Aged / Mode of action / Adult / Sodium channel / Lidocaine / Mechanism of action / Axons / Neurosciences / Pain Measurement / Time Course / Hyperalgesia / Laser Doppler Flowmetry
A Randomized, Controlled Trial Validates a Peripheral Supra-Additive Antihyperalgesic Effect of a Paracetamol-Ketorolac Combination
Pain / Inflammation / Humans / Male / Young Adult / Middle Aged / Adult / Gas Chromatography/mass Spectrometry / Acetaminophen / Ketorolac / Cross-Over Studies / Radiodermatitis / Analgesics / Hyperalgesia / Middle Aged / Adult / Gas Chromatography/mass Spectrometry / Acetaminophen / Ketorolac / Cross-Over Studies / Radiodermatitis / Analgesics / Hyperalgesia
JNJ-20788560 [9-(8-Azabicyclo[3.2.1]oct-3-ylidene)-9H-xanthene-3-carboxylic Acid Diethylamide], a Selective Delta Opioid Receptor Agonist, Is a Potent and Efficacious Antihyperalgesic Agent That Does Not Produce Respiratory Depression, Pharmacologic Tolerance, or Physical Dependence
Mice / Animals / Male / Self-administration / Rats / Gastrointestinal motility / Wistar Rats / Seizures / Opioid Receptor / Pain Measurement / Substance-Related Disorders / Hyperalgesia / *Hot Temperature / Drug Tolerance / Gastrointestinal motility / Wistar Rats / Seizures / Opioid Receptor / Pain Measurement / Substance-Related Disorders / Hyperalgesia / *Hot Temperature / Drug Tolerance
Opioid-Induced Hyperalgesia (OIH): A Real Clinical Problem or Just an Experimental Phenomenon?
Addiction / Pain / Humans / Postoperative pain / Neoplasms / Hyperalgesia
Orally Efficacious NR2B-Selective NMDA Receptor Antagonists
Organic Chemistry / Pain / Animals / Motor Coordination / Rats / Carrageenan / Side Effect / Bioorganic and medicinal Chemistry / Structure activity Relationship / Hyperalgesia / Psychomotor Performance / Carrageenan / Side Effect / Bioorganic and medicinal Chemistry / Structure activity Relationship / Hyperalgesia / Psychomotor Performance
Poly(ADP-Ribose) Polymerase Inhibition Alleviates Experimental Diabetic Sensory Neuropathy
Diabetes / Immunohistochemistry / Oxidative Stress / Apoptosis / Blood Glucose / Animals / Male / Neurons / Rats / Body Weight / Wistar Rats / Quinolines / Hyperalgesia / Tyrosine / Animals / Male / Neurons / Rats / Body Weight / Wistar Rats / Quinolines / Hyperalgesia / Tyrosine
Prostaglandin E2 glycerol ester, an endogenous COX-2 metabolite of 2-arachidonoylglycerol, induces hyperalgesia and modulates NFκB activity
Pain / Mass Spectrometry / British / Macrophages / Cell line / Mice / Animals / Male / NF-kappa B / Rats / Endocannabinoids / Pain Measurement / Hyperalgesia / *Hot Temperature / Prostaglandin E2 / Mice / Animals / Male / NF-kappa B / Rats / Endocannabinoids / Pain Measurement / Hyperalgesia / *Hot Temperature / Prostaglandin E2
JNJ-20788560 [9-(8-Azabicyclo[3.2.1]oct-3-ylidene)-9H-xanthene-3-carboxylic Acid Diethylamide], a Selective Delta Opioid Receptor Agonist, Is a Potent and Efficacious Antihyperalgesic Agent That Does Not Produce Respiratory Depression, Pharmacologic Tolerance, or Physical Dependence
Mice / Animals / Male / Self-administration / Rats / Gastrointestinal motility / Wistar Rats / Seizures / Opioid Receptor / Pain Measurement / Substance-Related Disorders / Hyperalgesia / *Hot Temperature / Drug Tolerance / Alfentanil / Gastrointestinal motility / Wistar Rats / Seizures / Opioid Receptor / Pain Measurement / Substance-Related Disorders / Hyperalgesia / *Hot Temperature / Drug Tolerance / Alfentanil
Tingenone, a Pentacyclic Triterpene, Induces Peripheral Antinociception Due to Opioidergic Activation
Complementary and Alternative Medicine / Plant Biology / Mice / Animals / Male / Analgesics / Hyperalgesia / Triterpenes / Maytenus / Analgesics / Hyperalgesia / Triterpenes / Maytenus
Soluble epoxide hydrolase limits mechanical hyperalgesia during inflammation
Inflammation / Calcium / Immunohistochemistry / Western blotting / Molecular / Mice / Transient receptor potential channels / Animals / Tandem Mass Spectrometry / High Performance Liquid Chromatography / Neurosciences / Hyperalgesia / Calcitonin Gene-Related Peptide / Mice / Transient receptor potential channels / Animals / Tandem Mass Spectrometry / High Performance Liquid Chromatography / Neurosciences / Hyperalgesia / Calcitonin Gene-Related Peptide
Hyperalgesia, nerve infiltration and nerve growth factor expression in deep adenomyotic nodules, peritoneal and ovarian endometriosis
Immunohistochemistry / Humans / Tyrosine Kinase Receptor / Female / Human reproduction / Adult / Endometriosis / Group / Physical examination / Nervous System / Nerve Growth Factor / Hyperalgesia / Adult / Endometriosis / Group / Physical examination / Nervous System / Nerve Growth Factor / Hyperalgesia
Olive (Olea europaea L.) leaf extract elicits antinociceptive activity, potentiates morphine analgesia and suppresses morphine hyperalgesia in rats
Pain / Complementary and Alternative Medicine / Traditional Medicine / Plant Biology / Interaction / Ethnopharmacology / Pharmacognosy / Olea europaea / Animals / Male / Analgesia / Morphine / Plant extracts / Rats / Rat / Wistar Rats / Extract / Pain Measurement / Olea / Analgesics / Hyperalgesia / Pain Threshold / Calcium Channel Blocker / Plant Leaves / Formalin Test / Ethnopharmacology / Pharmacognosy / Olea europaea / Animals / Male / Analgesia / Morphine / Plant extracts / Rats / Rat / Wistar Rats / Extract / Pain Measurement / Olea / Analgesics / Hyperalgesia / Pain Threshold / Calcium Channel Blocker / Plant Leaves / Formalin Test
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