Clinical Investigation

Enhanced coronary vasa vasorum neovascularization in experimental hypercholesterolemia

Female / Animals / Clinical / Hypercholesterolemia / Time Factors / Swine / X ray Computed Tomography / Clinical Investigation / Swine / X ray Computed Tomography / Clinical Investigation

MHC-restricted fratricide of human lymphocytes expressing survivin-specific transgenic T cell receptors

Cell line / Humans / Animals / Cell Death / T lymphocytes / Major histocompatibility complex / Lymphocytes / Clinical Investigation / Major histocompatibility complex / Lymphocytes / Clinical Investigation

Alzheimer disease β-amyloid activity mimics cholesterol oxidase

Brain / Humans / Copper / Mice / Cholesterol / Animals / Clinical / Male / Neurons / Aged / Adult / Chelating Agents / Alzheimer Disease / Clinical Investigation / Oxidation-Reduction / Molecular Structure / Animals / Clinical / Male / Neurons / Aged / Adult / Chelating Agents / Alzheimer Disease / Clinical Investigation / Oxidation-Reduction / Molecular Structure

Mesenchymal gene program–expressing ovarian cancer spheroids exhibit enhanced mesothelial clearance

Transcription Factors / Epithelial-Mesenchymal Transition / Transcriptome / Humans / Female / Neoplasm Invasiveness / Epithelium / Clinical Investigation / Neoplasm Invasiveness / Epithelium / Clinical Investigation

Heterogeneous response to calcium by individual parathyroid cells

Calcium / Immunohistochemistry / In Situ Hybridization / Animals / Parathyroid Hormone / Cattle / Adrenocorticotropic Hormone / Clinical Investigation / Cell Survival / Cattle / Adrenocorticotropic Hormone / Clinical Investigation / Cell Survival

Fatty acid amide hydrolase deficiency limits early pregnancy events

Pregnancy / Mice / Female / Animals / Clinical / Endocannabinoids / Clinical Investigation / Endocannabinoids / Clinical Investigation

Glutathione deficiency in type 2 diabetes impairs cytokine responses and control of intracellular bacteria

Disease susceptibility / Toll Like Receptors / Humans / Mice / Female / Animals / Male / Glutathione / Aged / Adult / Diabetes complications / Melioidosis / Type 2 Diabetes Mellitus / Clinical Investigation / Interleukin / Interferon gamma / Animals / Male / Glutathione / Aged / Adult / Diabetes complications / Melioidosis / Type 2 Diabetes Mellitus / Clinical Investigation / Interleukin / Interferon gamma

Toll-like receptor 4 deficiency causes pulmonary emphysema

Toll like receptor signaling / Antioxidants / Mice / Animals / Clinical / NADPH oxidase / Elastin / Clinical Investigation / Oxidants / NADPH oxidase / Elastin / Clinical Investigation / Oxidants

Antigen-specific CD4+ T cells drive airway smooth muscle remodeling in experimental asthma

Asthma / Apoptosis / Humans / Smooth muscle / Animals / Rats / Cell Proliferation / Cell communication / Clinical Investigation / Rats / Cell Proliferation / Cell communication / Clinical Investigation

Nuclear DNA origin of mitochondrial complex I deficiency in fatal infantile lactic acidosis evidenced by transnuclear complementation of cultured fibroblasts

Electron Microscopy / DNA / Mitochondrial DNA / Humans / Clinical / Male / Infant / Electron Transport / nuclear DNA / Newborn Infant / Cell nucleus / Hybrid Solar Cells / Clinical Investigation / DNA mutational analysis / Complex I / fibroblasts / genetic heterogeneity / Male / Infant / Electron Transport / nuclear DNA / Newborn Infant / Cell nucleus / Hybrid Solar Cells / Clinical Investigation / DNA mutational analysis / Complex I / fibroblasts / genetic heterogeneity

Mitochondrial respiration scavenges extramitochondrial superoxide anion via a nonenzymatic mechanism

Oxidative Stress / Mitochondria / Saccharomyces cerevisiae / Animals / Clinical / Electron Transport / Lung / Anions / Rats / Superoxide Anion / Clinical Investigation / Oxygen Consumption / Protons / Superoxides / Xanthine Oxidase / Electron Transport / Lung / Anions / Rats / Superoxide Anion / Clinical Investigation / Oxygen Consumption / Protons / Superoxides / Xanthine Oxidase

Germinal center dysregulation by histone methyltransferase EZH2 promotes lymphomagenesis

Cell Cycle / DNA damage / Transcription Factors / Apoptosis / Gene Silencing / Mice / Methylation / Animals / B Lymphocytes / Clinical Investigation / Germinal Center / Lymphopoiesis / Mice / Methylation / Animals / B Lymphocytes / Clinical Investigation / Germinal Center / Lymphopoiesis

M-CSF neutralization and Egr-1 deficiency prevent ovariectomy-induced bone loss

Transcription Factors / Antibodies / X Rays / Mice / Female / Animals / Clinical / Osteoclasts / Bone Density / Osteocalcin / Amino Acids / Bone Loss / Densitometry / Somatic Cell Count / Clinical Investigation / DNA binding proteins / Estradiol / Bone Resorption / Ovariectomy / Neutralization tests / Animals / Clinical / Osteoclasts / Bone Density / Osteocalcin / Amino Acids / Bone Loss / Densitometry / Somatic Cell Count / Clinical Investigation / DNA binding proteins / Estradiol / Bone Resorption / Ovariectomy / Neutralization tests

Lymphocyte adaptor protein LNK deficiency exacerbates hypertension and end-organ inflammation

Oxidative Stress / Kidney / Hypertension / Vasculitis / Animals / T lymphocytes / Clinical Investigation / Interferon gamma / Nephritis / T lymphocytes / Clinical Investigation / Interferon gamma / Nephritis

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