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Clinical Investigation
Clinical Investigation
Endothelial epsin deficiency decreases tumor growth by enhancing VEGF signaling
Signal Transduction / Humans / Mice / Endocytosis / Animals / Male / Cell Proliferation / Clinical Investigation / Vascular endothelial growth factor receptor / Male / Cell Proliferation / Clinical Investigation / Vascular endothelial growth factor receptor
Glucagon deficiency and hyperaminoacidemia after total pancreatectomy
Humans / Glucose / Blood Glucose / Insulin / Glucagon / Fasting / Female / Male / Middle Aged / Amino Acids / Adult / Arginine / Clinical Investigation / Fasting / Female / Male / Middle Aged / Amino Acids / Adult / Arginine / Clinical Investigation
Germinal center dysregulation by histone methyltransferase EZH2 promotes lymphomagenesis
Cell Cycle / DNA damage / Transcription Factors / Apoptosis / Gene Silencing / Mice / Methylation / Animals / B Lymphocytes / Clinical Investigation / Germinal Center / Mice / Methylation / Animals / B Lymphocytes / Clinical Investigation / Germinal Center
Human infection with Trypanosoma cruzi induces parasite antigen-specific cytotoxic T lymphocyte responses
Membrane Proteins / Cell line / Humans / Animals / Clinical / Immunization / Chagas disease / Neuraminidase / Trypanosoma Cruzi / Protein Binding / Clinical Investigation / Epitopes / Immunization / Chagas disease / Neuraminidase / Trypanosoma Cruzi / Protein Binding / Clinical Investigation / Epitopes
Paradoxical resistance to diet-induced obesity in UCP1-deficient mice
Obesity / Membrane Proteins / Ion Channels / Mice / Animal Feed / Telemetry / Animals / Temperature / Body Temperature / Time Factors / Calorimetry / Clinical Investigation / Oxygen Consumption / Telemetry / Animals / Temperature / Body Temperature / Time Factors / Calorimetry / Clinical Investigation / Oxygen Consumption
Disease expression and molecular genotype in congenital adrenal hyperplasia due to 21-hydroxylase deficiency
Humans / Mutation / Clinical / Pedigree / Phenotype / Congenital Adrenal Hyperplasia / Base Sequence / Clinical Investigation / Congenital Adrenal Hyperplasia / Base Sequence / Clinical Investigation
Lymphocyte adaptor protein LNK deficiency exacerbates hypertension and end-organ inflammation
Oxidative Stress / Kidney / Hypertension / Vasculitis / Animals / T lymphocytes / Clinical Investigation / Interferon gamma / T lymphocytes / Clinical Investigation / Interferon gamma
Lymphocyte adaptor protein LNK deficiency exacerbates hypertension and end-organ inflammation
Oxidative Stress / Kidney / Hypertension / Vasculitis / Animals / T lymphocytes / Clinical Investigation / Interferon gamma / T lymphocytes / Clinical Investigation / Interferon gamma
In vivo correction of ZAP-70 immunodeficiency by intrathymic gene transfer
Hematopoietic Stem Cells / Humans / Mice / Animals / Clinical / Lentivirus / T lymphocytes / Clinical Investigation / Severe combined immunodeficiency / Gene Transfer / Hematopoietic Stem Cell Transplantation / Lymphopoiesis / Lentivirus / T lymphocytes / Clinical Investigation / Severe combined immunodeficiency / Gene Transfer / Hematopoietic Stem Cell Transplantation / Lymphopoiesis
Lymphocyte adaptor protein LNK deficiency exacerbates hypertension and end-organ inflammation
Oxidative Stress / Kidney / Hypertension / Vasculitis / Animals / T lymphocytes / Clinical Investigation / Interferon gamma / T lymphocytes / Clinical Investigation / Interferon gamma
Lymphocyte adaptor protein LNK deficiency exacerbates hypertension and end-organ inflammation
Oxidative Stress / Kidney / Hypertension / Vasculitis / Animals / T lymphocytes / Clinical Investigation / Interferon gamma / T lymphocytes / Clinical Investigation / Interferon gamma
Endothelial mitochondrial oxidative stress determines podocyte depletion in segmental glomerulosclerosis
Oxidative Stress / Mitochondria / Signal Transduction / Cell line / Humans / Mice / Animals / Male / Vascular endothelium / Transforming Growth Factor Beta / Endothelin-1 / Clinical Investigation / Podocytes / Mice / Animals / Male / Vascular endothelium / Transforming Growth Factor Beta / Endothelin-1 / Clinical Investigation / Podocytes
Apolipoprotein C-II deficiency syndrome. Clinical features, lipoprotein characterization, lipase activity, and correction of hypertriglyceridemia after apolipoprotein C-II administration in two affected patients
Humans / Female / Clinical / Male / Lipoprotein(a) / Triglycerides / Adult / Lipoproteins / Genetic variation / Clinical Investigation / Lipase / Triglycerides / Adult / Lipoproteins / Genetic variation / Clinical Investigation / Lipase
TACI deficiency enhances antibody avidity and clearance of an intestinal pathogen
Apoptosis / Animals / T lymphocytes / B Lymphocytes / Cell Proliferation / Clinical Investigation / Germinal Center / Adoptive Transfer / Clinical Investigation / Germinal Center / Adoptive Transfer
Retinoic acid prevents experimental Cushing syndrome
Transcription Factors / Humans / Mice / Animals / Clinical / Retinoic Acid / Adrenocorticotropic Hormone / Tretinoin / Clinical Investigation / DNA binding proteins / Neuroendocrine Tumors / Cushing Syndrome / Pituitary Neoplasms / Retinoic Acid / Adrenocorticotropic Hormone / Tretinoin / Clinical Investigation / DNA binding proteins / Neuroendocrine Tumors / Cushing Syndrome / Pituitary Neoplasms
Vascular expression of extracellular superoxide dismutase in atherosclerosis
Immunohistochemistry / Macrophages / Mice / Animals / Clinical / Superoxide Dismutase / Molecular cloning / Recombinant Proteins / Aorta / Clinical Investigation / Extracellular Space / Superoxide Dismutase / Molecular cloning / Recombinant Proteins / Aorta / Clinical Investigation / Extracellular Space
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