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Cell Death
Cell Death
Differential distribution of presenilin-1, Bax, and Bcl-X L in Alzheimer\'s disease and frontotemporal dementia
Dementia / Membrane Proteins / Immunohistochemistry / Temporal Lobe / Humans / Cerebral Cortex / Female / Male / Cell Death / Clinical Sciences / Aged / ACTA / Frontotemporal Dementia / Presenilin-2 / Reference Values / Alzheimer Disease / Neurosciences / Frontal Lobe / Cerebral Cortex / Female / Male / Cell Death / Clinical Sciences / Aged / ACTA / Frontotemporal Dementia / Presenilin-2 / Reference Values / Alzheimer Disease / Neurosciences / Frontal Lobe
Apoptosis bcl-2 and nitrotyrosine expression in an angioplasty-restenosis rabbit: An experimental model
Surgery / Nonparametric Statistics / Cell Migration / Membrane Proteins / Apoptosis / Nitric oxide / Animals / Male / Cell Death / Recurrence / Clinical Sciences / Cell Proliferation / Rabbits / Tyrosine / Experimental Model / Nitric oxide / Animals / Male / Cell Death / Recurrence / Clinical Sciences / Cell Proliferation / Rabbits / Tyrosine / Experimental Model
Chronic Traumatic Encephalopathy in Athletes
Traumatic Brain Injury / Football / Sports / Brain / Humans / Female / Male / Cell Death / Astrocyte / Apolipoprotein E / Neurons / Tauopathies / Clinical Sciences / Aged / Middle Aged / Head injury / Adult / Degeneration / Disease Progression / Medial Temporal Lobe / Brain Chemistry / Neurosciences / Female / Male / Cell Death / Astrocyte / Apolipoprotein E / Neurons / Tauopathies / Clinical Sciences / Aged / Middle Aged / Head injury / Adult / Degeneration / Disease Progression / Medial Temporal Lobe / Brain Chemistry / Neurosciences
Circadian clock protein BMAL1 regulates cellular senescence in vivo
Cell Cycle / Oxidative Stress / DNA damage / Reactive Oxygen Species / Mice / Animals / Cell Death / Hydrogen Peroxide / Homeostasis / Time Factors / Primary Cell Culture / Human Fibroblasts / Antineoplastic Agents / Biochemistry and cell biology / Circadian Clocks / Animals / Cell Death / Hydrogen Peroxide / Homeostasis / Time Factors / Primary Cell Culture / Human Fibroblasts / Antineoplastic Agents / Biochemistry and cell biology / Circadian Clocks
Injurious Mechanical Compression of Bovine Articular Cartilage Induces Chondrocyte Apoptosis
Kinetics / Apoptosis / Collagen / Nitric oxide / Animals / Cell Death / Programmed cell death / Glycosaminoglycan / Cattle / Mechanical Stress / Articular Cartilage Wear / Chondrocytes / Articular Cartilage / Biochemistry and cell biology / Cell Death / Programmed cell death / Glycosaminoglycan / Cattle / Mechanical Stress / Articular Cartilage Wear / Chondrocytes / Articular Cartilage / Biochemistry and cell biology
Genetic expression in pancreatic adenocarcinoma cells predicts metastatic potential and response to oxidative stress
Genetics / Gene expression / Inflammatory Immune Response / Cell Death / Glutathione / Shear Stress / Superoxide Dismutase / Enzyme / Clinical Sciences / Hydrogen Peroxide / Endothelial cell / High Density Concrete / In Vitro Studies / Cell Proliferation / Surgical / MTT assay / Shear Stress / Superoxide Dismutase / Enzyme / Clinical Sciences / Hydrogen Peroxide / Endothelial cell / High Density Concrete / In Vitro Studies / Cell Proliferation / Surgical / MTT assay
Myristoyl-CoA:Protein N-Myristoyltransferase, an Essential Enzyme and Potential Drug Target in Kinetoplastid Parasites
Kinetics / Drug development / Biological Chemistry / Leishmania / Cell Division / Biological Sciences / Saccharomyces cerevisiae / Molecular / RNA interference / Virulence / Cell line / Humans / Mice / Endocytosis / Animals / Cell Death / Biological / Polymerase Chain Reaction / Capsid / Phenotype / Enzyme / CHEMICAL SCIENCES / Mouse Model / Rats / Trypanosoma / Trypanosoma brucei / Time Factors / Trypanosoma brucei brucei / Isoenzymes / Fatty Acid / Protozoan Proteins / Species Specificity / Amino Acid Sequence / Subcellular Fractions / Golgi Apparatus / Recombinant Proteins / Drug Targeting / Cell Survival / Leishmania Major / Biochemistry and cell biology / Poliovirus / Immunoblotting / Biological Sciences / Saccharomyces cerevisiae / Molecular / RNA interference / Virulence / Cell line / Humans / Mice / Endocytosis / Animals / Cell Death / Biological / Polymerase Chain Reaction / Capsid / Phenotype / Enzyme / CHEMICAL SCIENCES / Mouse Model / Rats / Trypanosoma / Trypanosoma brucei / Time Factors / Trypanosoma brucei brucei / Isoenzymes / Fatty Acid / Protozoan Proteins / Species Specificity / Amino Acid Sequence / Subcellular Fractions / Golgi Apparatus / Recombinant Proteins / Drug Targeting / Cell Survival / Leishmania Major / Biochemistry and cell biology / Poliovirus / Immunoblotting
Myristoyl CoA: protein N-myristoyltransferase: an essential enzyme and potential drug target in kinetoplastid parasites
Kinetics / Drug development / Biological Chemistry / Leishmania / Cell Division / Biological Sciences / Saccharomyces cerevisiae / Molecular / RNA interference / Virulence / Cell line / Humans / Mice / Endocytosis / Animals / Cell Death / Biological / Polymerase Chain Reaction / Capsid / Phenotype / Enzyme / CHEMICAL SCIENCES / Mouse Model / Rats / Trypanosoma / Trypanosoma brucei / Time Factors / Trypanosoma brucei brucei / Isoenzymes / Fatty Acid / Protozoan Proteins / Species Specificity / Amino Acid Sequence / Subcellular Fractions / Golgi Apparatus / Recombinant Proteins / Drug Targeting / Cell Survival / Leishmania Major / Biochemistry and cell biology / Poliovirus / Immunoblotting / Biological Sciences / Saccharomyces cerevisiae / Molecular / RNA interference / Virulence / Cell line / Humans / Mice / Endocytosis / Animals / Cell Death / Biological / Polymerase Chain Reaction / Capsid / Phenotype / Enzyme / CHEMICAL SCIENCES / Mouse Model / Rats / Trypanosoma / Trypanosoma brucei / Time Factors / Trypanosoma brucei brucei / Isoenzymes / Fatty Acid / Protozoan Proteins / Species Specificity / Amino Acid Sequence / Subcellular Fractions / Golgi Apparatus / Recombinant Proteins / Drug Targeting / Cell Survival / Leishmania Major / Biochemistry and cell biology / Poliovirus / Immunoblotting
A Locked Nucleic Acid Antisense Oligonucleotide (LNA) Silences PCSK9 and Enhances LDLR Expression In Vitro and In Vivo
Flow Cytometry / Multidisciplinary / Gene Silencing / Metabolic syndrome / Cell line / Humans / Mice / Animals / Cell Death / Polymerase Chain Reaction / PLoS one / LDL-cholesterol / Cardiovascular Risk Factor / Alanine Aminotransferase / Antisense Oligonucleotide Drugs / Familial Hypercholesterolemia / Cell Survival / Low Density Lipoprotein (LDL) / Intracellular Space / Oligonucleotides / Humans / Mice / Animals / Cell Death / Polymerase Chain Reaction / PLoS one / LDL-cholesterol / Cardiovascular Risk Factor / Alanine Aminotransferase / Antisense Oligonucleotide Drugs / Familial Hypercholesterolemia / Cell Survival / Low Density Lipoprotein (LDL) / Intracellular Space / Oligonucleotides
cGMP stimulates endoplasmic reticulum Ca2+-ATPase in vascular endothelial cells
Life Sciences / Enzyme Inhibitors / Animals / Male / Cell Death / Endoplasmic Reticulum / Vascular endothelium / Calcium Signaling / Alkaloids / Rats / Endothelial cell / cyclic GMP / Biochemistry and cell biology / Adenosine Triphosphate / Cell Growth / Sarcoplasmic reticulum / Endoplasmic Reticulum / Vascular endothelium / Calcium Signaling / Alkaloids / Rats / Endothelial cell / cyclic GMP / Biochemistry and cell biology / Adenosine Triphosphate / Cell Growth / Sarcoplasmic reticulum
Corresponding decrease in neuronal markers signals progressive parvalbumin neuron loss in MAM schizophrenia model
Schizophrenia / Hippocampus / Animals / Cell Death / Neurons / Neurotoxins / Rats / Analysis of Variance / Age Factors / Gene Expression Regulation / Neurotoxins / Rats / Analysis of Variance / Age Factors / Gene Expression Regulation
A DinB variant reveals diverse physiological consequences of incomplete TLS extension by a Y-family DNA polymerase
DNA repair / Multidisciplinary / Cell Death / Anti-Bacterial Agents / DNA Polymerase
Traumatic spinal cord injury induces nuclear factor-kappaB activation
Gene regulation / Immunohistochemistry / Macrophages / Spinal Cord Injury / Western blotting / Inflammatory Immune Response / Female / Animals / Spinal Cord / Microglia / Cell Death / NF-kappa B / The / Neurons / Transcription Factor / Electrophoresis / Rats / Nitric Oxide Synthase / Western blot / Monoclonal Antibody / Spinal Cord Injuries / Inflammatory Immune Response / Female / Animals / Spinal Cord / Microglia / Cell Death / NF-kappa B / The / Neurons / Transcription Factor / Electrophoresis / Rats / Nitric Oxide Synthase / Western blot / Monoclonal Antibody / Spinal Cord Injuries
A Permissive Apoptotic Environment: Function of a Decrease in Intracellular Superoxide Anion and Cytosolic Acidification
Apoptosis / Humans / Reactive Oxygen Species / Animals / Cell Death / Hydrogen Peroxide / Superoxide Anion / Hydrogen-Ion Concentration / Superoxides / Biochemistry and cell biology / Hydrogen Peroxide / Superoxide Anion / Hydrogen-Ion Concentration / Superoxides / Biochemistry and cell biology
Biochemical alteration in cerebrospinal fluid precedes behavioral deficits in Parkinsonian rats induced by 6-hydroxydopamine
Dopamine / Cerebrospinal Fluid / Animals / Male / Cell Death / Substantia nigra / Neurons / Tyrosine Hydroxylase / Clinical Sciences / Rats / Biological markers / Hypokinesia / Somatic Cell Count / Neurosciences / Movement Disorder / Substantia nigra / Neurons / Tyrosine Hydroxylase / Clinical Sciences / Rats / Biological markers / Hypokinesia / Somatic Cell Count / Neurosciences / Movement Disorder
The Synergistic Combination of the Farnesyl Transferase Inhibitor Lonafarnib and Paclitaxel Enhances Tubulin Acetylation and Requires a Functional Tubulin Deacetylase
Cancer / Mitosis / Cell line / Humans / Low Dose / Mice / Animals / HIstone Deacetylase / Cell Death / Paclitaxel / Microtubules / Acetylation / Pyridines / Tubulin / Histone deacetylase inhibitors / Histone deacetylases / Piperidines / Synergistic effect / Mice / Animals / HIstone Deacetylase / Cell Death / Paclitaxel / Microtubules / Acetylation / Pyridines / Tubulin / Histone deacetylase inhibitors / Histone deacetylases / Piperidines / Synergistic effect
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