Cell Death - Page 2

Multiple, Parallel Cellular Suicide Mechanisms Participate In Photoreceptor Cell Death

Complement activation / Metabolism / Oxidative Stress / Autophagy / Apoptosis / Gene expression / Glucose Metabolism / Laser Capture Microdissection / Mice / Animals / Cell Death / Retinal Degeneration / Animal Model / Caspase / Optometry and Ophthalmology / Time Factors / Degeneration / Environmental Stress / Complement / Temporal Analysis / Genetic Markers / Neurosciences / Time Course / Gene Expression Regulation / Gene expression / Glucose Metabolism / Laser Capture Microdissection / Mice / Animals / Cell Death / Retinal Degeneration / Animal Model / Caspase / Optometry and Ophthalmology / Time Factors / Degeneration / Environmental Stress / Complement / Temporal Analysis / Genetic Markers / Neurosciences / Time Course / Gene Expression Regulation

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Antiserum to activity-dependent neurotrophic factor produces neuronal cell death in CNS cultures: immunological and biological specificity

Cognitive Science / Comparative Study / Neuronal cell death / Antibodies / Neuropeptides / Cerebral Cortex / Mice / Animals / Spinal Cord / Cell Death / Central Nervous System / Neurons / Astrocytes / Neurotoxins / Epidermal Growth Factor / Rats / Vasoactive Intestinal Peptide / Neuronal Death / Tetrodotoxin / Nerve Growth Factor / Amino Acid Sequence / Growth Factor / Epitopes / Neurosciences / Size Exclusion Chromatography / Insulin Like Growth Factor / Terminal Deoxynucleotidyl Transferase / Neuroprotective Agents / Choline Acetyltransferase / Molecular Sequence Data / Cerebral Cortex / Mice / Animals / Spinal Cord / Cell Death / Central Nervous System / Neurons / Astrocytes / Neurotoxins / Epidermal Growth Factor / Rats / Vasoactive Intestinal Peptide / Neuronal Death / Tetrodotoxin / Nerve Growth Factor / Amino Acid Sequence / Growth Factor / Epitopes / Neurosciences / Size Exclusion Chromatography / Insulin Like Growth Factor / Terminal Deoxynucleotidyl Transferase / Neuroprotective Agents / Choline Acetyltransferase / Molecular Sequence Data

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Multiple, Parallel Cellular Suicide Mechanisms Participate In Photoreceptor Cell Death

Complement activation / Metabolism / Oxidative Stress / Autophagy / Apoptosis / Gene expression / Glucose Metabolism / Laser Capture Microdissection / Mice / Animals / Cell Death / Retinal Degeneration / Animal Model / Caspase / Optometry and Ophthalmology / Time Factors / Degeneration / Environmental Stress / Complement / Temporal Analysis / Genetic Markers / Neurosciences / Time Course / Gene Expression Regulation / Gene expression / Glucose Metabolism / Laser Capture Microdissection / Mice / Animals / Cell Death / Retinal Degeneration / Animal Model / Caspase / Optometry and Ophthalmology / Time Factors / Degeneration / Environmental Stress / Complement / Temporal Analysis / Genetic Markers / Neurosciences / Time Course / Gene Expression Regulation

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Hyperoxic Treatment Induces Mesenchymal-to-Epithelial Transition in a Rat Adenocarcinoma Model

Immunohistochemistry / Gene expression / Multidisciplinary / Tumor Hypoxia / Female / Animals / Cell Death / PLoS one / Rats / Epithelial cells / Hyperbaric Oxygen / Hyperoxia / Tumor Growth / Blood Vessel / Epithelial to Mesenchymal Transition / Control Group / Adenocarcinoma / Treatment Effect / Animals / Cell Death / PLoS one / Rats / Epithelial cells / Hyperbaric Oxygen / Hyperoxia / Tumor Growth / Blood Vessel / Epithelial to Mesenchymal Transition / Control Group / Adenocarcinoma / Treatment Effect

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Gene expression profiling in vLINCL CLN6-deficient fibroblasts: Insights into pathobiology

Membrane Proteins / Extracellular Matrix / Molecular Mechanics / Biological Sciences / Humans / Cell Mechanics / Cholesterol / Cell Death / Physical sciences / Statistical Significance / Signal Transduction Pathway Models / Clinical Sciences / Lipid Raft / Neurodegenerative Disease / Cdna Microarray / Human Fibroblasts / Structure Function / Biochemistry and cell biology / Gene expression profiling / Inflammatory response / Cell Mechanics / Cholesterol / Cell Death / Physical sciences / Statistical Significance / Signal Transduction Pathway Models / Clinical Sciences / Lipid Raft / Neurodegenerative Disease / Cdna Microarray / Human Fibroblasts / Structure Function / Biochemistry and cell biology / Gene expression profiling / Inflammatory response

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Intramembrane proteolytic cleavage by human signal peptide peptidase like 3 and malaria signal peptide peptidase

Physiology / Membrane Proteins / Enzyme Inhibitors / Humans / Animals / Cell Death / Hepatitis C Virus / Medical Physiology / Molecular cloning / Active site / Plasmodium falciparum / Protozoan Proteins / MHC class I / Biochemistry and cell biology / Proteolytic activity / Cell Death / Hepatitis C Virus / Medical Physiology / Molecular cloning / Active site / Plasmodium falciparum / Protozoan Proteins / MHC class I / Biochemistry and cell biology / Proteolytic activity

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Partial mitochondrial complex I inhibition induces oxidative damage and perturbs glutamate transport in primary retinal cultures

Neurobiology Of Disease / Free Radicals / Oxidative Stress / Mitochondria / Neurobiology / Energy Metabolism / Free Radical / Glutamate / Mitochondrial DNA / Animals / Cell Death / Retina / Glial Cell / Neurons / Lipid peroxidation / Clinical Sciences / Rats / Oxidative Damage / Degeneration / Retinal Ganglion Cells / Wistar Rats / Neurosciences / Glutamic Acid / Glutamate Transporter / Energy Metabolism / Free Radical / Glutamate / Mitochondrial DNA / Animals / Cell Death / Retina / Glial Cell / Neurons / Lipid peroxidation / Clinical Sciences / Rats / Oxidative Damage / Degeneration / Retinal Ganglion Cells / Wistar Rats / Neurosciences / Glutamic Acid / Glutamate Transporter

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Transgenic expression of human acetylcholinesterase induces progressive cognitive deterioration in mice

Aging / Molecular Mechanics / Transgenic Mice / Biological Sciences / Learning and Memory / Humans / Mice / Animals / Cell Death / Acetylcholinesterase / Open Field / Central Nervous System / Animal Model / Acetylcholine / Spatial Learning / Neurons / Cholinesterase inhibitors / Structural Change / Enzyme / Locomotor Activity / Neuromuscular Junction / Transgene Expression / Cognition disorders / Water maze / Humans / Mice / Animals / Cell Death / Acetylcholinesterase / Open Field / Central Nervous System / Animal Model / Acetylcholine / Spatial Learning / Neurons / Cholinesterase inhibitors / Structural Change / Enzyme / Locomotor Activity / Neuromuscular Junction / Transgene Expression / Cognition disorders / Water maze

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MK-954 (losartan potassium) exerts endothelial protective effects against reperfusion injury: evidence of an e-NOS mRNA overexpression after global ischemia

Atherosclerosis / Internal Control / Renin Angiotensin Aldosterone System / Nitric oxide / Animals / Male / Cell Death / Vascular endothelium / Potassium / Endothelial dysfunction / Creatine Kinase / Clinical Sciences / mRna expression levels / Rats / Nitric Oxide Synthase / Myocardium / Wistar Rats / Coronary Circulation / Losartan / Reperfusion injury / Ischemia–reperfusion / Male / Cell Death / Vascular endothelium / Potassium / Endothelial dysfunction / Creatine Kinase / Clinical Sciences / mRna expression levels / Rats / Nitric Oxide Synthase / Myocardium / Wistar Rats / Coronary Circulation / Losartan / Reperfusion injury / Ischemia–reperfusion

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Amyloid beta peptide 1–42 disturbs intracellular calcium homeostasis through activation of GluN2B-containing N-methyl-d-aspartate receptors in cortical cultures

Physiology / Calcium / Cerebral Cortex / Animals / Cell Death / Synaptic Transmission / Medical Physiology / Neurons / Rats / Homeostasis / Alzheimer Disease / Biochemistry and cell biology / Synaptic Transmission / Medical Physiology / Neurons / Rats / Homeostasis / Alzheimer Disease / Biochemistry and cell biology

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Myristoyl-CoA:Protein N-Myristoyltransferase, an Essential Enzyme and Potential Drug Target in Kinetoplastid Parasites

Kinetics / Drug development / Biological Chemistry / Leishmania / Cell Division / Biological Sciences / Saccharomyces cerevisiae / Molecular / RNA interference / Virulence / Cell line / Humans / Mice / Endocytosis / Animals / Cell Death / Biological / Polymerase Chain Reaction / Capsid / Phenotype / Enzyme / CHEMICAL SCIENCES / Mouse Model / Rats / Trypanosoma / Trypanosoma brucei / Time Factors / Trypanosoma brucei brucei / Isoenzymes / Fatty Acid / Protozoan Proteins / Species Specificity / Amino Acid Sequence / Subcellular Fractions / Golgi Apparatus / Recombinant Proteins / Drug Targeting / Cell Survival / Leishmania Major / Biochemistry and cell biology / Poliovirus / Immunoblotting / Biological Sciences / Saccharomyces cerevisiae / Molecular / RNA interference / Virulence / Cell line / Humans / Mice / Endocytosis / Animals / Cell Death / Biological / Polymerase Chain Reaction / Capsid / Phenotype / Enzyme / CHEMICAL SCIENCES / Mouse Model / Rats / Trypanosoma / Trypanosoma brucei / Time Factors / Trypanosoma brucei brucei / Isoenzymes / Fatty Acid / Protozoan Proteins / Species Specificity / Amino Acid Sequence / Subcellular Fractions / Golgi Apparatus / Recombinant Proteins / Drug Targeting / Cell Survival / Leishmania Major / Biochemistry and cell biology / Poliovirus / Immunoblotting

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Myristoyl-CoA:protein N-myristoyltransferase, an essential enzyme and potential drug target in kinetoplastid parasites

Kinetics / Drug development / Biological Chemistry / Leishmania / Cell Division / Biological Sciences / Saccharomyces cerevisiae / Molecular / RNA interference / Virulence / Cell line / Humans / Mice / Endocytosis / Animals / Cell Death / Biological / Polymerase Chain Reaction / Capsid / Phenotype / Enzyme / CHEMICAL SCIENCES / Mouse Model / Rats / Trypanosoma / Trypanosoma brucei / Time Factors / Trypanosoma brucei brucei / Isoenzymes / Fatty Acid / Protozoan Proteins / Species Specificity / Amino Acid Sequence / Subcellular Fractions / Golgi Apparatus / Recombinant Proteins / Drug Targeting / Cell Survival / Leishmania Major / Biochemistry and cell biology / Poliovirus / Immunoblotting / Biological Sciences / Saccharomyces cerevisiae / Molecular / RNA interference / Virulence / Cell line / Humans / Mice / Endocytosis / Animals / Cell Death / Biological / Polymerase Chain Reaction / Capsid / Phenotype / Enzyme / CHEMICAL SCIENCES / Mouse Model / Rats / Trypanosoma / Trypanosoma brucei / Time Factors / Trypanosoma brucei brucei / Isoenzymes / Fatty Acid / Protozoan Proteins / Species Specificity / Amino Acid Sequence / Subcellular Fractions / Golgi Apparatus / Recombinant Proteins / Drug Targeting / Cell Survival / Leishmania Major / Biochemistry and cell biology / Poliovirus / Immunoblotting

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The DUX4 gene at the FSHD1A locus encodes a pro-apoptotic protein

Membrane Proteins / Apoptosis / Gene expression / Cell line / Humans / Muscular Dystrophy / Cell Death / Rhabdomyosarcoma / Medical Physiology / Chromatin structure / Clinical Sciences / Nuclear envelope / Neuromuscular Disorders / Amino Acid Sequence / Neuromuscular / Neurosciences / Muscular Dystrophy / Cell Death / Rhabdomyosarcoma / Medical Physiology / Chromatin structure / Clinical Sciences / Nuclear envelope / Neuromuscular Disorders / Amino Acid Sequence / Neuromuscular / Neurosciences

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Cell-Permeable Gomesin Peptide Promotes Cell Death by Intracellular Ca 2+ Overload

Calcium / Mitochondria / Signal Transduction / Cell line / Reactive Oxygen Species / Animals / Cell Death / Endoplasmic Reticulum / Antimicrobial Cationic Peptides / Cytoplasm / Molecular Pharmaceutics / Animals / Cell Death / Endoplasmic Reticulum / Antimicrobial Cationic Peptides / Cytoplasm / Molecular Pharmaceutics

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Cell cooperation in coelomocyte cytotoxic activity of Paracentrotus lividus coelomocytes

Physiology / Zoology / Innate immunity / Cell separation / Cell line / Humans / Animals / Cell Death / Density gradient / Cytotoxic Activity / Sea Urchin / Paracentrotus lividus / Rabbits / Cell communication / Erythrocytes / Biochemistry and cell biology / Humans / Animals / Cell Death / Density gradient / Cytotoxic Activity / Sea Urchin / Paracentrotus lividus / Rabbits / Cell communication / Erythrocytes / Biochemistry and cell biology

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PARP-1 Inhibition Increases Mitochondrial Metabolism through SIRT1 Activation

Skeletal muscle biology / Oxidative Stress / Mitochondria / DNA damage / Energy Metabolism / RNA interference / Mice / Animals / Cell Death / Phenotype / Brown Adipose Tissue / NAD / Sirtuin / Biochemistry and cell biology / RNA interference / Mice / Animals / Cell Death / Phenotype / Brown Adipose Tissue / NAD / Sirtuin / Biochemistry and cell biology

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